NO20081036L - Fremgangsmater for oppnaelse av fenylkarbamater - Google Patents
Fremgangsmater for oppnaelse av fenylkarbamaterInfo
- Publication number
- NO20081036L NO20081036L NO20081036A NO20081036A NO20081036L NO 20081036 L NO20081036 L NO 20081036L NO 20081036 A NO20081036 A NO 20081036A NO 20081036 A NO20081036 A NO 20081036A NO 20081036 L NO20081036 L NO 20081036L
- Authority
- NO
- Norway
- Prior art keywords
- phenylcarbamates
- obtaining
- reaction
- ethyl
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- PWXJULSLLONQHY-UHFFFAOYSA-N phenylcarbamic acid Chemical class OC(=O)NC1=CC=CC=C1 PWXJULSLLONQHY-UHFFFAOYSA-N 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- -1 carbamoyl halide Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 102000003914 Cholinesterases Human genes 0.000 abstract 1
- 108090000322 Cholinesterases Proteins 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- XSVMFMHYUFZWBK-NSHDSACASA-N Rivastigmine Chemical compound CCN(C)C(=O)OC1=CC=CC([C@H](C)N(C)C)=C1 XSVMFMHYUFZWBK-NSHDSACASA-N 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000005576 amination reaction Methods 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229940048961 cholinesterase Drugs 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 229960004136 rivastigmine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/50—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200501969A ES2267399B1 (es) | 2005-08-04 | 2005-08-04 | Procedimiento para la obtencion de carbamatos de fenilo. |
| PCT/ES2006/000459 WO2007014973A2 (es) | 2005-08-04 | 2006-08-03 | Procedimiento para la obtención de carbamatos de fenilo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20081036L true NO20081036L (no) | 2008-04-23 |
Family
ID=37709657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20081036A NO20081036L (no) | 2005-08-04 | 2008-02-27 | Fremgangsmater for oppnaelse av fenylkarbamater |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1939172B1 (ru) |
| JP (1) | JP2009503036A (ru) |
| KR (1) | KR20080046176A (ru) |
| CN (1) | CN101277929A (ru) |
| AU (1) | AU2006274824A1 (ru) |
| BR (1) | BRPI0614395A2 (ru) |
| CA (1) | CA2618452A1 (ru) |
| ES (2) | ES2267399B1 (ru) |
| NO (1) | NO20081036L (ru) |
| RU (1) | RU2008108169A (ru) |
| WO (1) | WO2007014973A2 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7884121B2 (en) | 2007-06-11 | 2011-02-08 | Apotex Pharmachem Inc. | Process for the preparation of phenylcarbamates |
| CN101910110B (zh) | 2008-01-10 | 2013-05-22 | 上海医药工业研究院 | 利凡斯的明的制备方法、其中间体以及中间体的制备方法 |
| EP2349976B1 (en) * | 2008-08-25 | 2012-12-26 | Jubilant Life Sciences Limited | A process for producing (s)-3-[(1-dimethylamino)ethyl]phenyl-n-ethyl-n-methyl-carbamate via novel intermediates |
| CN104151176B (zh) * | 2014-08-29 | 2016-08-24 | 大连韦德生化科技有限公司 | 一种卡巴拉汀手性中间体及其制备方法 |
| JP7688348B2 (ja) * | 2020-06-05 | 2025-06-04 | 国立研究開発法人産業技術総合研究所 | カルバミン酸エステルの製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6504208A (ru) * | 1964-04-03 | 1965-10-04 | ||
| IL74497A (en) | 1985-03-05 | 1990-02-09 | Proterra Ag | Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives |
| NL195004C (nl) | 1987-03-04 | 2003-11-04 | Novartis Ag | Fenylcarbamaat bevattend farmaceutisch preparaat. |
| AU2003263574A1 (en) | 2002-05-31 | 2003-12-19 | Patel, Hetalkumar, Virendrabhai | A process for the preparation of phenylcarbamates |
| CZ293014B6 (cs) * | 2002-10-24 | 2004-01-14 | Léčiva, A.S. | Způsob výroby (-)-(S)-3-[1-(dimethylamino)ethyl]fenyl-N-ethyl-N-methylkarbamátu |
| EP1856036B1 (en) * | 2004-11-08 | 2016-12-14 | Emcure Pharmaceuticals Limited | An efficient method for preparation of (s)-3-[(1-dimethyl amino)ethyl]-phenyl-n-ethyl-n-methyl-carbamate |
| KR20060072326A (ko) * | 2004-12-23 | 2006-06-28 | 동국제약 주식회사 | 페닐카바메이트 유도체의 새로운 합성 방법 |
-
2005
- 2005-08-04 ES ES200501969A patent/ES2267399B1/es not_active Expired - Fee Related
-
2006
- 2006-08-03 EP EP06807907A patent/EP1939172B1/en active Active
- 2006-08-03 AU AU2006274824A patent/AU2006274824A1/en not_active Abandoned
- 2006-08-03 KR KR1020087005395A patent/KR20080046176A/ko not_active Withdrawn
- 2006-08-03 BR BRPI0614395-4A patent/BRPI0614395A2/pt not_active Application Discontinuation
- 2006-08-03 ES ES06807907T patent/ES2391032T3/es active Active
- 2006-08-03 RU RU2008108169/04A patent/RU2008108169A/ru not_active Application Discontinuation
- 2006-08-03 CN CNA2006800368801A patent/CN101277929A/zh active Pending
- 2006-08-03 JP JP2008524534A patent/JP2009503036A/ja active Pending
- 2006-08-03 WO PCT/ES2006/000459 patent/WO2007014973A2/es not_active Ceased
- 2006-08-03 CA CA002618452A patent/CA2618452A1/en not_active Abandoned
-
2008
- 2008-02-27 NO NO20081036A patent/NO20081036L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101277929A (zh) | 2008-10-01 |
| WO2007014973A2 (es) | 2007-02-08 |
| JP2009503036A (ja) | 2009-01-29 |
| EP1939172A4 (en) | 2011-03-23 |
| RU2008108169A (ru) | 2009-09-10 |
| WO2007014973A3 (es) | 2007-05-03 |
| EP1939172A2 (en) | 2008-07-02 |
| BRPI0614395A2 (pt) | 2011-03-29 |
| AU2006274824A1 (en) | 2007-02-08 |
| ES2267399A1 (es) | 2007-03-01 |
| ES2391032T3 (es) | 2012-11-20 |
| CA2618452A1 (en) | 2007-02-08 |
| KR20080046176A (ko) | 2008-05-26 |
| ES2267399B1 (es) | 2008-02-01 |
| EP1939172B1 (en) | 2012-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |