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NO20081934L - Diaryleterderivater som antitumor midler - Google Patents

Diaryleterderivater som antitumor midler

Info

Publication number
NO20081934L
NO20081934L NO20081934A NO20081934A NO20081934L NO 20081934 L NO20081934 L NO 20081934L NO 20081934 A NO20081934 A NO 20081934A NO 20081934 A NO20081934 A NO 20081934A NO 20081934 L NO20081934 L NO 20081934L
Authority
NO
Norway
Prior art keywords
group
formula
antitumor agents
ether derivatives
hydrogen atom
Prior art date
Application number
NO20081934A
Other languages
English (en)
Norwegian (no)
Inventor
Takashi Nakagawa
Hironori Matsuyama
Kenji Ohnishi
Hideki Takasu
Makoto Sakamoto
Kumi Higuchi
Keisuke Miyajima
Satoshi Yamada
Masaaki Motoyama
Yutaka Kojima
Koichi Yasumura
Takeshi Kodama
Shun Otsuji
Keizo Kan
Takumi Sumida
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO20081934L publication Critical patent/NO20081934L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20081934A 2005-12-05 2008-04-23 Diaryleterderivater som antitumor midler NO20081934L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005351255 2005-12-05
PCT/JP2006/324610 WO2007066784A2 (fr) 2005-12-05 2006-12-04 Substance medicamenteuse

Publications (1)

Publication Number Publication Date
NO20081934L true NO20081934L (no) 2008-08-13

Family

ID=38051953

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081934A NO20081934L (no) 2005-12-05 2008-04-23 Diaryleterderivater som antitumor midler

Country Status (21)

Country Link
US (1) US8236826B2 (fr)
EP (1) EP1957073B1 (fr)
KR (1) KR101157004B1 (fr)
CN (1) CN101321529B (fr)
AR (1) AR056885A1 (fr)
AU (1) AU2006323700B2 (fr)
BR (1) BRPI0619349A2 (fr)
CA (1) CA2630468C (fr)
CY (1) CY1115171T1 (fr)
DK (1) DK1957073T3 (fr)
ES (1) ES2463450T3 (fr)
IL (1) IL191544A0 (fr)
MY (1) MY146514A (fr)
NO (1) NO20081934L (fr)
PL (1) PL1957073T3 (fr)
PT (1) PT1957073E (fr)
RU (1) RU2444362C2 (fr)
SI (1) SI1957073T1 (fr)
TW (1) TWI332838B (fr)
WO (1) WO2007066784A2 (fr)
ZA (1) ZA200804445B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0514150A (pt) 2004-08-06 2007-11-27 Otsuka Pharma Co Ltd composto aromático ou um sal do mesmo, método para produzir o mesmo, e, composição farmacêutica para tratar a fibrose
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
CN101597278B (zh) 2008-06-04 2013-04-17 中国中化股份有限公司 酰胺类化合物及其制备与应用
KR20110088575A (ko) 2008-11-21 2011-08-03 하이 포인트 파마슈티칼스, 엘엘씨 아다만틸 벤즈아미드 화합물
WO2010122980A1 (fr) * 2009-04-20 2010-10-28 田辺三菱製薬株式会社 Nouvel agoniste du récepteur ss de l'hormone thyroïdienne
WO2011047156A1 (fr) 2009-10-15 2011-04-21 Hercules Technology Management Co V, Inc. Inhibiteurs de sépiaptérine réductase pour le traitement de la douleur
NZ601794A (en) * 2010-01-29 2014-04-30 Otsuka Pharma Co Ltd Di - substituted pyridine derivatives as anticancers
WO2012015715A1 (fr) 2010-07-27 2012-02-02 High Point Pharmaceuticals, Llc Dérivés de thiazol-2-ylamine substitués, compositions pharmaceutiques et procédés d'utilisation en tant que modulateurs de 11-bêta-hsd1
MX2013003589A (es) 2010-10-04 2013-06-24 Otsuka Pharmaceuticals Co Ltd Derivados de 4-(metilaminofenoxi)piridin-3-il-benzamida para tratar cancer.
WO2012090177A2 (fr) * 2010-12-30 2012-07-05 Lupin Limited Modulateurs des récepteurs cannabinoïdes
WO2013005168A2 (fr) * 2011-07-05 2013-01-10 Lupin Limited Modulateurs des récepteurs de cannabinoïdes
TW201329025A (zh) 2011-11-01 2013-07-16 Astex Therapeutics Ltd 醫藥化合物
CA2859842C (fr) 2012-03-14 2016-11-08 Sinochem Corporation Composes de diphenylamine substitues et leur utilisation en tant qu'agents antitumoraux
JP6066806B2 (ja) * 2012-04-03 2017-01-25 大塚製薬株式会社 医薬
US9463192B2 (en) 2013-02-19 2016-10-11 Ono Pharmaceutical Co., Ltd. Trk-inhibiting compound
EP3417852B1 (fr) * 2013-09-09 2020-02-19 Peloton Therapeutics, Inc. Éthers d'aryle et leurs utilisations
ES2842592T3 (es) * 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
TW201617314A (zh) * 2014-09-10 2016-05-16 第一三共股份有限公司 羧酸衍生物
CN107098884A (zh) * 2016-02-19 2017-08-29 中国科学院上海药物研究所 一类取代的氨基吡啶类化合物及其制备和用途
WO2020059841A1 (fr) * 2018-09-21 2020-03-26 国立大学法人 長崎大学 Agent thérapeutique pour maladies à prions
CN118765280A (zh) * 2022-02-28 2024-10-11 维泰瑞隆有限公司 Rip1调节剂、其制备及用途

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629102A (fr) 1961-03-29
US3715375A (en) 1970-09-17 1973-02-06 Merck & Co Inc New diphenyl sulfones
NL7111711A (fr) 1970-09-17 1972-03-21
GB1494117A (en) 1974-11-02 1977-12-07 Bayer Ag Process for the preparation of acid amides
DE2707660C2 (de) 1977-02-23 1985-12-19 Bayer Ag, 5090 Leverkusen Abspalter- und Diolrest enthaltende Diisocyanat-Addukte, ihre Herstellung und Verwendung
DE2707659A1 (de) 1977-02-23 1978-08-24 Bayer Ag Selbstvernetzbare polyurethane
DE2812252A1 (de) 1978-03-21 1979-10-04 Bayer Ag 1,2,4-triazol-blockierte polyisocyanate als vernetzer fuer lackbindemittel
US4978672A (en) 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
EP0500495A3 (en) 1991-02-21 1993-04-07 Ciba-Geigy Ag Thermosetting composition
DK0580550T3 (da) 1992-07-21 1998-02-02 Ciba Geigy Ag Oxamidsyrederivater som hypercholesterolæmiske midler
IL110159A0 (en) 1993-06-30 1994-10-07 Wellcome Found Diaryl compounds, their preparation and pharmaceutical compositions containing them
CA2223948A1 (fr) 1995-06-07 1996-12-19 Rui Han Retinoides de chalcone et leurs procedes d'utilisation
US6022884A (en) 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
WO1999040073A2 (fr) 1998-02-06 1999-08-12 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibiteurs de la tryptase
EP1060175B1 (fr) 1998-02-06 2004-11-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibiteurs de la tryptase
AR015733A1 (es) 1998-03-25 2001-05-16 Otsuka Pharma Co Ltd DERIVADO DE PIRIDINA, EL PRODUCTO Y LA COMPOSICIoN FARMACEUTICA QUE CONTIENE DICHO DERIVADO.
TWI245035B (en) 1998-06-26 2005-12-11 Ono Pharmaceutical Co Amino acid derivatives and a pharmaceutical composition comprising the derivatives
DE69920923T2 (de) * 1998-07-24 2005-10-20 Teijin Ltd. Anthranilsäurederivate
WO2000042012A1 (fr) 1999-01-13 2000-07-20 Bayer Corporation DIPHENYLUREES A SUBSTITUANTS φ-CARBOXYARYLES, INHIBITRICES DE KINASE RAF
US20020065296A1 (en) 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
MXPA01007957A (es) 1999-02-04 2002-07-30 Millennium Pharm Inc Receptor helicoidal acoplado a la proteina-g que une compuestos y metodos para el uso del mismo.
CO5160290A1 (es) 1999-03-29 2002-05-30 Novartis Ag Derivados de acido fenoxifeniloxamico sustituido .
US6159694A (en) 1999-04-08 2000-12-12 Isis Pharmaceuticals Inc. Antisense modulation of stat3 expression
CN1372548A (zh) 1999-07-01 2002-10-02 味之素株式会社 杂环化合物及其医药用途
JP2001089412A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
JP2001089450A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ピリジン誘導体含有医薬製剤
WO2001060354A1 (fr) * 2000-02-15 2001-08-23 Teijin Limited Medicament anticancereux comprenant un derive d'acide anthranilique en tant qu'ingredient actif
DZ3347A1 (fr) 2000-05-22 2001-11-29 Aventis Pharma Inc Dérivés d'arylméthylamine pour leur utilisation comme inhibiteurs de la tryptase
GB0015205D0 (en) 2000-06-21 2000-08-09 Karobio Ab Bioisosteric thyroid receptor ligands and method
AU2001282874A1 (en) 2000-08-18 2002-03-04 Pharmacia And Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
EP1379127B1 (fr) 2000-09-28 2013-04-17 Nanocyte Inc. Procedes, compositions et dispositifs utilisant des cellules/capsules urticantes pour administrer un agent therapeutique ou cosmetique dans un tissu
AU2002223626A1 (en) 2000-10-20 2002-04-29 Novartis Ag Combinations of a thyromimetic compound and a statin
EP1211235A3 (fr) 2000-11-30 2004-01-02 JFE Chemical Corporation Procédé de préparation d'éthers d'acide diphényldicarboxylique et ses dérivés
JP2004269356A (ja) 2000-12-27 2004-09-30 Ajinomoto Co Inc 創傷部癒着防止剤
GB2374009A (en) 2001-02-12 2002-10-09 Novartis Ag Method of treating hair loss
OA12623A (en) 2001-06-20 2006-06-12 Pfizer Prod Inc Novel sulfonic acid derivatives.
WO2003018586A1 (fr) 2001-08-24 2003-03-06 Pharmacia & Upjohn Company Aryl 7-aza[2.2.1]bicycloheptanes substitues utiles dans le traitement de maladies
ATE456559T1 (de) 2001-10-22 2010-02-15 Pfizer Prod Inc Piperazinderivate mit ccr1-rezeptor- antagonistischer wirkung
WO2003035602A1 (fr) 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
AU2003210730A1 (en) 2002-02-15 2003-09-09 Pharmacia And Upjohn Company Azabicyclo-substituted benzoylamides and thioamides for treatment of cns-related disorders
FR2836917B1 (fr) 2002-03-11 2006-02-24 Lipha Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif
JP2004035475A (ja) 2002-07-03 2004-02-05 Ajinomoto Co Inc TGFβ作用抑制剤
EP2385040A1 (fr) * 2003-03-14 2011-11-09 ONO Pharmaceutical Co., Ltd. Dérivés hétérocycliques renfermant de l'azote et médicaments contenant ces dérivés comme principe actif
WO2005007621A2 (fr) 2003-05-30 2005-01-27 Rigel Pharmaceuticals, Inc. Inhibiteurs de ligase d'ubiquitine
BRPI0412893A (pt) 2003-07-24 2006-10-03 Leo Pharma As composto, composição farmacêutica, uso de um composto, e, métodos de prevenção, tratamento ou melhora de doenças ou condições inflamatórias, ou doenças ou condições oftálmicas, de tratamento ou melhora de cáncer e para a produção de um composto
BRPI0514150A (pt) * 2004-08-06 2007-11-27 Otsuka Pharma Co Ltd composto aromático ou um sal do mesmo, método para produzir o mesmo, e, composição farmacêutica para tratar a fibrose
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
TWI440638B (zh) * 2007-10-30 2014-06-11 Otsuka Pharma Co Ltd 雜環化合物及其藥學組成物

Also Published As

Publication number Publication date
CN101321529B (zh) 2012-09-05
US20100004438A1 (en) 2010-01-07
RU2008127325A (ru) 2010-01-20
KR20080070054A (ko) 2008-07-29
US8236826B2 (en) 2012-08-07
RU2444362C2 (ru) 2012-03-10
AU2006323700A1 (en) 2007-06-14
CA2630468A1 (fr) 2007-06-14
AU2006323700B2 (en) 2011-02-17
PT1957073E (pt) 2014-05-12
SI1957073T1 (sl) 2014-08-29
CN101321529A (zh) 2008-12-10
TWI332838B (en) 2010-11-11
AR056885A1 (es) 2007-10-31
WO2007066784A3 (fr) 2007-10-25
EP1957073A2 (fr) 2008-08-20
WO2007066784A2 (fr) 2007-06-14
EP1957073B1 (fr) 2014-04-23
ES2463450T3 (es) 2014-05-28
BRPI0619349A2 (pt) 2011-11-08
TW200800200A (en) 2008-01-01
KR101157004B1 (ko) 2012-07-09
HK1123219A1 (en) 2009-06-12
MY146514A (en) 2012-08-15
CA2630468C (fr) 2015-01-20
PL1957073T3 (pl) 2014-09-30
CY1115171T1 (el) 2016-12-14
ZA200804445B (en) 2009-11-25
IL191544A0 (en) 2008-12-29
DK1957073T3 (da) 2014-05-12

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