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NO20081595L - Raf-inhibitorforbindelser og fremgangsmater for anvendelse derav - Google Patents

Raf-inhibitorforbindelser og fremgangsmater for anvendelse derav

Info

Publication number
NO20081595L
NO20081595L NO20081595A NO20081595A NO20081595L NO 20081595 L NO20081595 L NO 20081595L NO 20081595 A NO20081595 A NO 20081595A NO 20081595 A NO20081595 A NO 20081595A NO 20081595 L NO20081595 L NO 20081595L
Authority
NO
Norway
Prior art keywords
methods
inhibitor compounds
compounds
raf inhibitor
formula
Prior art date
Application number
NO20081595A
Other languages
English (en)
Inventor
Joseph P Lyssikatos
Greg Miknis
Ellen Laird
Eugene Tarlton
Alexandre J Buckmelter
Li Ren
Bryson Rast
Stephen T Schlachter
Steven Mark Wenglowsky
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of NO20081595L publication Critical patent/NO20081595L/no

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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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Abstract

Forbindelser med formel I er anvendbare til inhibering av Raf-kinase og til behandling av forstyrrelser formidlet ved den. Fremgangsmåte for anvendelse av forbindelser med formel I og stereoisomerer, geometriske isomerer, tautomerer, solvater og farmasøytisk akseptable salter derav, for in vitro, in situ og in vivo diagnose, profylakse eller behandling av slike forstyrrelser i pattedyrceller, eller assosierte patologiske tilstander, er beskrevet.
NO20081595A 2005-09-01 2008-03-31 Raf-inhibitorforbindelser og fremgangsmater for anvendelse derav NO20081595L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71363005P 2005-09-01 2005-09-01
PCT/US2006/033976 WO2007027855A2 (en) 2005-09-01 2006-08-31 Raf inhibitor compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
NO20081595L true NO20081595L (no) 2008-06-02

Family

ID=37744290

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081595A NO20081595L (no) 2005-09-01 2008-03-31 Raf-inhibitorforbindelser og fremgangsmater for anvendelse derav

Country Status (13)

Country Link
US (1) US20070049603A1 (no)
EP (1) EP1934228A2 (no)
JP (1) JP2009507024A (no)
KR (1) KR20080052630A (no)
CN (1) CN101305010A (no)
AU (1) AU2006284751A1 (no)
BR (1) BRPI0615781A2 (no)
CA (1) CA2620864A1 (no)
IL (1) IL189771A0 (no)
NO (1) NO20081595L (no)
RU (1) RU2008112313A (no)
WO (1) WO2007027855A2 (no)
ZA (1) ZA200802822B (no)

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WO2007027855A3 (en) 2007-05-03
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KR20080052630A (ko) 2008-06-11
IL189771A0 (en) 2008-08-07
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