NO20076003L - TGF-beta 1 spesifikke antistoffer - Google Patents
TGF-beta 1 spesifikke antistofferInfo
- Publication number
- NO20076003L NO20076003L NO20076003A NO20076003A NO20076003L NO 20076003 L NO20076003 L NO 20076003L NO 20076003 A NO20076003 A NO 20076003A NO 20076003 A NO20076003 A NO 20076003A NO 20076003 L NO20076003 L NO 20076003L
- Authority
- NO
- Norway
- Prior art keywords
- tgf
- beta
- specific antibodies
- compositions
- methods
- Prior art date
Links
- 102000004887 Transforming Growth Factor beta Human genes 0.000 title abstract 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 title abstract 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67408205P | 2005-04-22 | 2005-04-22 | |
| PCT/US2006/014943 WO2006116002A2 (fr) | 2005-04-22 | 2006-04-20 | Compositions de liaison; reactifs connexes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076003L true NO20076003L (no) | 2008-01-22 |
Family
ID=37192643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076003A NO20076003L (no) | 2005-04-22 | 2007-11-21 | TGF-beta 1 spesifikke antistoffer |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7619069B2 (fr) |
| EP (1) | EP1874818B1 (fr) |
| JP (1) | JP5070200B2 (fr) |
| KR (1) | KR100978684B1 (fr) |
| CN (1) | CN101163719A (fr) |
| AT (1) | ATE505489T1 (fr) |
| AU (1) | AU2006240056B2 (fr) |
| BR (1) | BRPI0608376A8 (fr) |
| CA (1) | CA2607448C (fr) |
| CY (1) | CY1111518T1 (fr) |
| DE (1) | DE602006021292D1 (fr) |
| DK (1) | DK1874818T3 (fr) |
| EA (1) | EA016038B1 (fr) |
| ES (1) | ES2361269T3 (fr) |
| HR (1) | HRP20110334T1 (fr) |
| IL (1) | IL186775A (fr) |
| NO (1) | NO20076003L (fr) |
| PL (1) | PL1874818T3 (fr) |
| PT (1) | PT1874818E (fr) |
| RS (1) | RS51845B (fr) |
| SI (1) | SI1874818T1 (fr) |
| UA (1) | UA93201C2 (fr) |
| WO (1) | WO2006116002A2 (fr) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2334330A4 (fr) * | 2008-09-29 | 2013-05-15 | Janssen Biotech Inc | Anticorps anti-cd147, procédés, et utilisations |
| ES2528799T3 (es) * | 2008-11-22 | 2015-02-12 | Astute Medical, Inc. | Métodos para el pronóstico de insuficiencia renal aguda |
| US8685932B2 (en) * | 2008-12-16 | 2014-04-01 | Option Pharmaceuticals, Llc | Targeted transforming growth factor-beta-bound IgG for Treatment of Diseases |
| CA3150199C (fr) | 2009-01-09 | 2025-07-22 | Seagen Inc | Regimes posologiques hebdomadaires pour des conjugues anticorps anti-cd30 vc-pab-mmae - medicament |
| WO2012129330A1 (fr) | 2011-03-23 | 2012-09-27 | Option Pharmaceutical, Llc | Cytokine ciblée pour le traitement de maladies musculosquelettiques |
| AU2012261933B2 (en) * | 2011-06-03 | 2017-06-15 | Xoma Technology Ltd. | Antibodies specific for TGF-beta |
| SG11201401360XA (en) | 2011-10-25 | 2014-05-29 | Onclave Therapeutics Ltd | Antibody formulations and methods |
| DK2822592T3 (en) | 2012-03-08 | 2018-10-15 | Ludwig Institute For Cancer Res Limited | TGF-1-SPECIFIC ANTIBODIES AND PROCEDURES AND APPLICATIONS THEREOF |
| US10259626B2 (en) | 2012-03-08 | 2019-04-16 | Selig Sealing Products, Inc. | Container sealing member with protected security component and removal tab |
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| CA2911514A1 (fr) | 2013-05-06 | 2014-11-13 | Scholar Rock, Inc. | Compositions et procedes de modulation du facteur de croissance |
| PT3107573T (pt) * | 2014-02-19 | 2019-01-10 | Merck Patent Gmbh | Imunoterapia com il-12 visada ao cancro |
| WO2016115345A1 (fr) | 2015-01-14 | 2016-07-21 | The Brigham And Women's Hospital, | Traitement du cancer avec des anticorps monoclonaux anti-lap |
| TWI726870B (zh) * | 2015-03-04 | 2021-05-11 | 美商健臻公司 | 具有高親和性、結合性及專一性之結合轉形生長因子-β1的scFv-Fc二聚體 |
| TWI733661B (zh) | 2015-03-04 | 2021-07-21 | 美商健臻公司 | 以高親合性、結合性及特異性結合轉化生長因子-β1的經修飾IgG抗體 |
| SG11201805941WA (en) | 2016-02-17 | 2018-09-27 | Novartis Ag | Tgfbeta 2 antibodies |
| AU2017222928A1 (en) * | 2016-02-26 | 2018-09-20 | Eli Lilly And Company | Anti-CD11d antibodies and uses thereof |
| EP4169942A1 (fr) * | 2016-03-11 | 2023-04-26 | Scholar Rock, Inc. | Immunoglobulines se liant à tgfbeta1 et leur utilisation |
| CA3024465A1 (fr) | 2016-05-17 | 2017-11-23 | Genentech, Inc. | Signatures genetiques stromales destinees au diagnostic et a l'utilisation en immunotherapie |
| AU2017268469C1 (en) * | 2016-05-20 | 2025-01-02 | President And Fellows Of Harvard College | Gene therapy methods for age-related diseases and conditions |
| CA3029003A1 (fr) | 2016-06-27 | 2018-01-04 | The Regents Of The University Of California | Associations medicamenteuses pour le traitement du cancer |
| WO2018043734A1 (fr) * | 2016-09-05 | 2018-03-08 | Chugai Seiyaku Kabushiki Kaisha | Anticorps anti-tgf-beta 1 et leurs procédés d'utilisation |
| CN109071656B (zh) | 2017-01-05 | 2021-05-18 | 璟尚生物制药公司 | 检查点调节物拮抗剂 |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| SG11201909955XA (en) | 2017-05-02 | 2019-11-28 | Merck Sharp & Dohme | Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies |
| WO2019045086A1 (fr) * | 2017-08-29 | 2019-03-07 | 林化成株式会社 | UTILISATION D'UN ANTICORPS SPÉCIFIQUE POUR TGF-β1 ACTIF OU LATENT |
| EP3694552A1 (fr) | 2017-10-10 | 2020-08-19 | Tilos Therapeutics, Inc. | Anticorps anti-lap et leurs utilisations |
| AU2018359967A1 (en) | 2017-11-06 | 2020-04-23 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
| WO2020006516A1 (fr) | 2018-06-29 | 2020-01-02 | Gensun Biopharma, Inc. | Antagonistes des régulateurs de points de contrôle immunitaires antitumoraux |
| WO2020076969A2 (fr) | 2018-10-10 | 2020-04-16 | Tilos Therapeutics, Inc. | Variants d'anticorps anti-lap et leurs utilisations |
| EP3876990A4 (fr) | 2018-11-07 | 2023-09-06 | Merck Sharp & Dohme LLC | Co-formulations d'anticorps anti-lag3 et d'anticorps anti-pd-1 |
| EA202192130A1 (ru) | 2019-01-30 | 2021-12-28 | Сколар Рок, Инк. | Специфичные к ltbp-комплексу ингибиторы tgf и их применение |
| WO2020263312A1 (fr) | 2019-06-28 | 2020-12-30 | Gensun Biopharma, Inc. | ANTAGONISTE ANTITUMORAL COMPOSÉ D'UN DOMAINE EXTRACELLULAIRE TGFβ1 - RII MUTÉ ET D'UN ÉCHAFAUDAGE D'IMMUNOGLOBULINE |
| JP2023511255A (ja) | 2020-01-11 | 2023-03-17 | スカラー ロック インコーポレイテッド | TGF-β阻害剤及びその使用 |
| CN115190812A (zh) | 2020-01-11 | 2022-10-14 | 供石公司 | TGFβ抑制剂及其用途 |
| WO2022204581A2 (fr) | 2021-03-26 | 2022-09-29 | Scholar Rock, Inc. | Inhibiteurs de tgf-bêta et leur utilisation |
| WO2022256723A2 (fr) | 2021-06-03 | 2022-12-08 | Scholar Rock, Inc. | Inhibiteurs de tgf-bêta et leur utilisation thérapeutique |
| WO2022266510A1 (fr) * | 2021-06-18 | 2022-12-22 | Genzyme Corporation | Formulations d'anticorps anti-tgf-bêta et leur utilisation |
| EP4370148A1 (fr) | 2021-07-14 | 2024-05-22 | Scholar Rock, Inc. | Inhibiteurs spécifiques du complexe ltbp de tgf bêta1 et leurs utilisations |
| WO2023080900A1 (fr) | 2021-11-05 | 2023-05-11 | Genentech, Inc. | Procédés et compositions pour classer et traiter le cancer rénal |
| EP4599089A1 (fr) | 2022-10-05 | 2025-08-13 | Genentech, Inc. | Méthodes et compositions de classification et de traitement du cancer de la vessie |
| EP4599088A1 (fr) | 2022-10-05 | 2025-08-13 | Genentech, Inc. | Procédés et compositions pour la classification et le traitement du cancer du poumon |
| WO2024187051A1 (fr) | 2023-03-07 | 2024-09-12 | Scholar Rock, Inc. | Inhibiteurs de tgf-bêta destinés à être utilisés pour traiter un cancer résistant ou réfractaire chez des patients |
| WO2025240343A1 (fr) | 2024-05-13 | 2025-11-20 | Scholar Rock, Inc. | Inhibiteurs de tgf-bêta pour le traitement du cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| GB9601081D0 (en) | 1995-10-06 | 1996-03-20 | Cambridge Antibody Tech | Specific binding members for human transforming growth factor beta;materials and methods |
| US7368111B2 (en) * | 1995-10-06 | 2008-05-06 | Cambridge Antibody Technology Limited | Human antibodies specific for TGFβ2 |
| CA2358400C (fr) | 1999-01-05 | 2012-05-15 | Nancy A. Noble | Procedes de traitement d'etats associes a l'accumulation d'un excedent de matrice extracellulaire |
| US7763580B2 (en) * | 1999-01-05 | 2010-07-27 | University Of Utah Research Foundation | Methods for treating conditions associated with the accumulation of excess extracellular matrix |
| US6492497B1 (en) * | 1999-04-30 | 2002-12-10 | Cambridge Antibody Technology Limited | Specific binding members for TGFbeta1 |
| WO2004098637A1 (fr) | 2003-04-30 | 2004-11-18 | Genzyme Corporation | Antagonistes du tgf-beta combine avec des antagonistes du systeme renine-angiotensine-aldosterone pour le traitement de l'insuffisance renale |
| EP1646655A2 (fr) * | 2003-07-09 | 2006-04-19 | Eli Lilly And Company | Ligands de tgf-beta1 |
| US20070148170A1 (en) * | 2005-10-03 | 2007-06-28 | Desjarlais John R | Fc Variants With Optimized Fc Receptor Binding Properties |
| CA2561686C (fr) | 2004-03-31 | 2014-12-02 | Genentech, Inc. | Anticorps anti-tgf-beta humanises |
| AU2005251764A1 (en) | 2004-06-04 | 2005-12-22 | Genentech, Inc. | Method for treating lupus |
-
2006
- 2006-04-20 ES ES06750860T patent/ES2361269T3/es active Active
- 2006-04-20 CN CNA2006800135110A patent/CN101163719A/zh active Pending
- 2006-04-20 RS RS20110195A patent/RS51845B/sr unknown
- 2006-04-20 PL PL06750860T patent/PL1874818T3/pl unknown
- 2006-04-20 WO PCT/US2006/014943 patent/WO2006116002A2/fr not_active Ceased
- 2006-04-20 HR HR20110334T patent/HRP20110334T1/hr unknown
- 2006-04-20 DK DK06750860.6T patent/DK1874818T3/da active
- 2006-04-20 EP EP06750860A patent/EP1874818B1/fr active Active
- 2006-04-20 AT AT06750860T patent/ATE505489T1/de active
- 2006-04-20 DE DE602006021292T patent/DE602006021292D1/de active Active
- 2006-04-20 EA EA200702278A patent/EA016038B1/ru not_active IP Right Cessation
- 2006-04-20 AU AU2006240056A patent/AU2006240056B2/en not_active Ceased
- 2006-04-20 JP JP2008507883A patent/JP5070200B2/ja not_active Expired - Fee Related
- 2006-04-20 SI SI200631049T patent/SI1874818T1/sl unknown
- 2006-04-20 KR KR1020077024149A patent/KR100978684B1/ko not_active Expired - Fee Related
- 2006-04-20 CA CA2607448A patent/CA2607448C/fr not_active Expired - Fee Related
- 2006-04-20 BR BRPI0608376A patent/BRPI0608376A8/pt not_active IP Right Cessation
- 2006-04-20 UA UAA200711364A patent/UA93201C2/ru unknown
- 2006-04-20 PT PT06750860T patent/PT1874818E/pt unknown
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2007
- 2007-10-18 IL IL186775A patent/IL186775A/en not_active IP Right Cessation
- 2007-10-19 US US11/874,952 patent/US7619069B2/en not_active Expired - Fee Related
- 2007-11-21 NO NO20076003A patent/NO20076003L/no not_active Application Discontinuation
-
2009
- 2009-10-15 US US12/579,447 patent/US8128927B2/en not_active Expired - Fee Related
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2011
- 2011-05-13 CY CY20111100455T patent/CY1111518T1/el unknown
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