NO20074722L - Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienter - Google Patents
Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienterInfo
- Publication number
- NO20074722L NO20074722L NO20074722A NO20074722A NO20074722L NO 20074722 L NO20074722 L NO 20074722L NO 20074722 A NO20074722 A NO 20074722A NO 20074722 A NO20074722 A NO 20074722A NO 20074722 L NO20074722 L NO 20074722L
- Authority
- NO
- Norway
- Prior art keywords
- kinase inhibitor
- egrr
- growth factor
- factor receptor
- epidermal growth
- Prior art date
Links
- 239000005411 L01XE02 - Gefitinib Substances 0.000 title abstract 3
- XGALLCVXEZPNRQ-UHFFFAOYSA-N gefitinib Chemical compound C=12C=C(OCCCN3CCOCC3)C(OC)=CC2=NC=NC=1NC1=CC=C(F)C(Cl)=C1 XGALLCVXEZPNRQ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960002584 gefitinib Drugs 0.000 title abstract 2
- 102000001301 EGF receptor Human genes 0.000 title 1
- 108060006698 EGF receptor Proteins 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000002254 cytotoxic agent Substances 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 229940121647 egfr inhibitor Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940084651 iressa Drugs 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67128705P | 2005-04-14 | 2005-04-14 | |
| PCT/US2006/012877 WO2006113151A2 (en) | 2005-04-14 | 2006-04-07 | Use of an epidermal growth factor receptor kinase inhibitor (egfr) in gefitinib resistant patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074722L true NO20074722L (no) | 2007-11-12 |
Family
ID=36791648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074722A NO20074722L (no) | 2005-04-14 | 2007-09-17 | Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienter |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20060235046A1 (es) |
| EP (1) | EP1871371A2 (es) |
| JP (1) | JP2008536847A (es) |
| KR (1) | KR20080002826A (es) |
| CN (1) | CN101160129A (es) |
| AR (1) | AR053357A1 (es) |
| AU (1) | AU2006236940A1 (es) |
| BR (1) | BRPI0610574A2 (es) |
| CA (1) | CA2646257A1 (es) |
| CR (1) | CR9415A (es) |
| GT (1) | GT200600146A (es) |
| IL (1) | IL186302A0 (es) |
| MX (1) | MX2007012662A (es) |
| NO (1) | NO20074722L (es) |
| PE (1) | PE20061396A1 (es) |
| RU (1) | RU2007134908A (es) |
| TW (1) | TW200718421A (es) |
| WO (1) | WO2006113151A2 (es) |
| ZA (1) | ZA200708755B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1848414T3 (da) * | 2005-02-03 | 2011-07-25 | Gen Hospital Corp | Fremgangsmåde til behandling af gefitinib-resistent cancer |
| AU2006311877A1 (en) * | 2005-11-04 | 2007-05-18 | Wyeth Llc | Antineoplastic combinations with mTOR inhibitor, herceptin, and/orHKI-272 |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| SI2310011T1 (sl) | 2008-06-17 | 2013-10-30 | Wyeth Llc | Antineoplastične kombinacije, ki vsebujejo HKI-272 in vinorelbin |
| BRPI0916694B1 (pt) * | 2008-08-04 | 2021-06-08 | Wyeth Llc | uso de neratinibe em combinação com capecitabina para tratar câncer de mama metastático de erbb-2 positivo, kit e produto compreendendo os mesmos |
| CN102405284B (zh) * | 2008-09-05 | 2016-01-20 | 新基阿维罗米克斯研究公司 | 设计不可逆抑制剂的算法 |
| WO2010086382A1 (en) * | 2009-01-30 | 2010-08-05 | Pronota N.V. | Target for treatment of acute heart failure |
| CA2755789C (en) | 2009-04-06 | 2016-01-19 | Wyeth Llc | Treatment regimen utilizing neratinib for breast cancer |
| EP2478361A4 (en) * | 2009-09-16 | 2014-05-21 | Celgene Avilomics Res Inc | CONJUGATES AND INHIBITORS OF PROTEIN KINASE |
| CN102812167A (zh) | 2009-12-30 | 2012-12-05 | 阿维拉制药公司 | 蛋白的配体-介导的共价修饰 |
| RU2021109549A (ru) | 2014-08-29 | 2021-05-13 | Тес Фарма С.Р.Л. | ИНГИБИТОРЫ α-АМИНО-β-КАРБОКСИМУКОНАТ ε-СЕМИАЛЬДЕГИД-ДЕКАРБОКСИЛАЗЫ |
| US9364469B1 (en) * | 2015-08-26 | 2016-06-14 | Macau University Of Science And Technology | Identification of a new AMPK activator for treatment of lung cancer |
| EP3849538A4 (en) | 2018-09-10 | 2022-06-29 | Mirati Therapeutics, Inc. | Combination therapies |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| RU2006106267A (ru) * | 2003-08-01 | 2006-07-27 | Уайт Холдингз Корпорейшн (Us) | Применение комбинации ингибитора киназы рецептора эпидермального фактора роста и цитотоксических средств для лечения и ингибирования рака |
| US7399865B2 (en) * | 2003-09-15 | 2008-07-15 | Wyeth | Protein tyrosine kinase enzyme inhibitors |
| EP1733056B1 (en) * | 2004-03-31 | 2013-05-22 | The General Hospital Corporation | Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments |
| DK1848414T3 (da) * | 2005-02-03 | 2011-07-25 | Gen Hospital Corp | Fremgangsmåde til behandling af gefitinib-resistent cancer |
-
2006
- 2006-04-07 RU RU2007134908/14A patent/RU2007134908A/ru not_active Application Discontinuation
- 2006-04-07 EP EP06740650A patent/EP1871371A2/en not_active Withdrawn
- 2006-04-07 WO PCT/US2006/012877 patent/WO2006113151A2/en not_active Ceased
- 2006-04-07 CN CNA2006800123594A patent/CN101160129A/zh active Pending
- 2006-04-07 AU AU2006236940A patent/AU2006236940A1/en not_active Abandoned
- 2006-04-07 BR BRPI0610574-2A patent/BRPI0610574A2/pt not_active IP Right Cessation
- 2006-04-07 MX MX2007012662A patent/MX2007012662A/es unknown
- 2006-04-07 CA CA002646257A patent/CA2646257A1/en not_active Abandoned
- 2006-04-07 JP JP2008506526A patent/JP2008536847A/ja not_active Withdrawn
- 2006-04-07 KR KR1020077023472A patent/KR20080002826A/ko not_active Withdrawn
- 2006-04-10 TW TW095112747A patent/TW200718421A/zh unknown
- 2006-04-10 GT GT200600146A patent/GT200600146A/es unknown
- 2006-04-12 AR ARP060101468A patent/AR053357A1/es unknown
- 2006-04-12 US US11/403,170 patent/US20060235046A1/en not_active Abandoned
- 2006-04-17 PE PE2006000400A patent/PE20061396A1/es not_active Application Discontinuation
-
2007
- 2007-09-17 NO NO20074722A patent/NO20074722L/no not_active Application Discontinuation
- 2007-09-25 IL IL186302A patent/IL186302A0/en unknown
- 2007-10-04 CR CR9415A patent/CR9415A/es not_active Application Discontinuation
- 2007-10-12 ZA ZA200708755A patent/ZA200708755B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006113151A3 (en) | 2007-01-11 |
| ZA200708755B (en) | 2008-10-29 |
| EP1871371A2 (en) | 2008-01-02 |
| TW200718421A (en) | 2007-05-16 |
| AR053357A1 (es) | 2007-05-02 |
| WO2006113151A2 (en) | 2006-10-26 |
| MX2007012662A (es) | 2008-04-04 |
| BRPI0610574A2 (pt) | 2010-07-06 |
| CN101160129A (zh) | 2008-04-09 |
| AU2006236940A1 (en) | 2006-10-26 |
| IL186302A0 (en) | 2008-08-07 |
| JP2008536847A (ja) | 2008-09-11 |
| CA2646257A1 (en) | 2006-10-26 |
| CR9415A (es) | 2008-01-21 |
| US20060235046A1 (en) | 2006-10-19 |
| RU2007134908A (ru) | 2009-05-20 |
| KR20080002826A (ko) | 2008-01-04 |
| PE20061396A1 (es) | 2007-01-12 |
| GT200600146A (es) | 2006-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |