NO20072934L - Anvendelse av Ranolazon i kombinasjon med minst ett remodelleringsmiddel for a reversere remodellering av venstre ventikkel ved behandlingen av hjertesvikt - Google Patents
Anvendelse av Ranolazon i kombinasjon med minst ett remodelleringsmiddel for a reversere remodellering av venstre ventikkel ved behandlingen av hjertesviktInfo
- Publication number
- NO20072934L NO20072934L NO20072934A NO20072934A NO20072934L NO 20072934 L NO20072934 L NO 20072934L NO 20072934 A NO20072934 A NO 20072934A NO 20072934 A NO20072934 A NO 20072934A NO 20072934 L NO20072934 L NO 20072934L
- Authority
- NO
- Norway
- Prior art keywords
- remodeling
- treatment
- heart failure
- left ventricular
- ranolazon
- Prior art date
Links
- 206010019280 Heart failures Diseases 0.000 title abstract 2
- 208000033774 Ventricular Remodeling Diseases 0.000 title abstract 2
- 238000007634 remodeling Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- XKLMZUWKNUAPSZ-UHFFFAOYSA-N N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide Chemical compound COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC=2C(=CC=CC=2C)C)CC1 XKLMZUWKNUAPSZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 239000002876 beta blocker Substances 0.000 abstract 1
- 229940097320 beta blocking agent Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960000213 ranolazine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Foreliggende oppfinnelse vedrører en fremgangsmåte for å reversere venstre ventrikkelremodellering ved kombinert administrering av terapeutisk effektive mengder av ranolazin og minst ett samtidig remodellerende middel, som kan være en ACEinhibitor, en ARB eller en betablokker. Fremgangsmåten finner anvendelse i behandlingen av hjertesvikt. Denne oppfinnelsen vedrører også farmasøytiske forrnuleringer som er passende for slike kombinerte administreringer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62615404P | 2004-11-09 | 2004-11-09 | |
| PCT/US2005/040824 WO2006053161A1 (en) | 2004-11-09 | 2005-11-09 | Use ranolazine in combination with at least one remodeling agent for reversing left ventricular remodeling in the treatment of heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072934L true NO20072934L (no) | 2007-08-08 |
Family
ID=35892429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072934A NO20072934L (no) | 2004-11-09 | 2007-06-08 | Anvendelse av Ranolazon i kombinasjon med minst ett remodelleringsmiddel for a reversere remodellering av venstre ventikkel ved behandlingen av hjertesvikt |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20060111361A1 (no) |
| EP (1) | EP1809289A1 (no) |
| JP (1) | JP2008519770A (no) |
| KR (1) | KR20070084063A (no) |
| CN (1) | CN101072562A (no) |
| AU (1) | AU2005304421A1 (no) |
| BR (1) | BRPI0517650A (no) |
| CA (1) | CA2586840A1 (no) |
| IL (1) | IL183056A0 (no) |
| MX (1) | MX2007005367A (no) |
| NO (1) | NO20072934L (no) |
| RU (1) | RU2007121707A (no) |
| SG (1) | SG156681A1 (no) |
| WO (1) | WO2006053161A1 (no) |
| ZA (1) | ZA200703697B (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040063717A1 (en) * | 2002-05-21 | 2004-04-01 | Andrew Wolff | Method of treating diabetes |
| JP5522663B2 (ja) * | 2006-09-08 | 2014-06-18 | カーディオポリマーズ, インコーポレイテッド | 全体的な心臓のサイズ変更および再形成のための心筋内パターン形成 |
| US20090012413A1 (en) * | 2006-09-08 | 2009-01-08 | Sabbah Hani N | Cardiac patterning for improving diastolic function |
| WO2008080012A1 (en) * | 2006-12-21 | 2008-07-03 | Cv Therapeutics, Inc. | Reduction of cardiovascular symptoms |
| US20080248112A1 (en) * | 2007-02-13 | 2008-10-09 | Brent Blackburn | Use of ranolazine for the treatment of coronary microvascular diseases |
| US20090111826A1 (en) * | 2007-02-13 | 2009-04-30 | Louis Lange | Use of ranolazine for the treatment of cardiovascular diseases |
| WO2008101012A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of non-coronary microvascular diseases |
| JP2010518169A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 心血管疾患の処置のためのラノラジンの使用 |
| US20080233191A1 (en) * | 2007-03-22 | 2008-09-25 | Brent Blackburn | Use of ranolazine for elevated brain-type natriuretic peptide |
| JP2010523264A (ja) * | 2007-04-11 | 2010-07-15 | ヘンリー フォード ヘルス システム | 心臓の静脈系を用いた心臓の修復、リサイジング、およびリシェイピング |
| CN101896181A (zh) * | 2007-05-31 | 2010-11-24 | 吉利德帕洛阿尔托股份有限公司 | 用于升高的脑钠肽的雷诺嗪 |
| US20090012103A1 (en) * | 2007-07-05 | 2009-01-08 | Matthew Abelman | Substituted heterocyclic compounds |
| WO2010132696A1 (en) * | 2009-05-14 | 2010-11-18 | Gilead Palo Alto, Inc. | Ranolazine for the treatment of cns disorders |
| AU2009202685B1 (en) | 2009-06-30 | 2010-08-19 | Ino Therapeutics Llc | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
| JP6998942B2 (ja) * | 2016-09-19 | 2022-01-18 | アビオメド インコーポレイテッド | 心機能を定量化し、心臓の回復を促進する心血管補助システム |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0719558T3 (da) * | 1989-06-23 | 2002-10-07 | Syntex Llc | Ranolzin og beslægtede piperazin til anvendelse ved behandling af chocktilstande |
| US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
| US6323226B1 (en) * | 1999-10-19 | 2001-11-27 | Texas Heart Institute | Treatment of heart disease with cox-2 inhibitors |
| MXPA02007639A (es) * | 2000-02-18 | 2004-08-23 | Cv Therapeutics Inc | Inhibidores de la oxidacion parcial de los acidos grasos en el tratamiento de la falla cardiaca congestiva. |
| US20020052377A1 (en) * | 2000-07-21 | 2002-05-02 | Wolff Andrew A. | Method for treating angina |
| US20030220344A1 (en) * | 2002-04-04 | 2003-11-27 | Luiz Belardinelli | Method of treating arrhythmias |
-
2005
- 2005-11-09 RU RU2007121707/14A patent/RU2007121707A/ru not_active Application Discontinuation
- 2005-11-09 KR KR1020077010435A patent/KR20070084063A/ko not_active Withdrawn
- 2005-11-09 WO PCT/US2005/040824 patent/WO2006053161A1/en not_active Ceased
- 2005-11-09 AU AU2005304421A patent/AU2005304421A1/en not_active Abandoned
- 2005-11-09 CN CNA2005800380175A patent/CN101072562A/zh active Pending
- 2005-11-09 MX MX2007005367A patent/MX2007005367A/es unknown
- 2005-11-09 CA CA002586840A patent/CA2586840A1/en not_active Abandoned
- 2005-11-09 EP EP05826116A patent/EP1809289A1/en not_active Withdrawn
- 2005-11-09 US US11/271,168 patent/US20060111361A1/en not_active Abandoned
- 2005-11-09 SG SG200907097-0A patent/SG156681A1/en unknown
- 2005-11-09 BR BRPI0517650-6A patent/BRPI0517650A/pt not_active IP Right Cessation
- 2005-11-09 JP JP2007540416A patent/JP2008519770A/ja not_active Withdrawn
-
2007
- 2007-05-08 IL IL183056A patent/IL183056A0/en unknown
- 2007-05-08 ZA ZA200703697A patent/ZA200703697B/xx unknown
- 2007-06-08 NO NO20072934A patent/NO20072934L/no not_active Application Discontinuation
-
2009
- 2009-02-26 US US12/393,952 patent/US20090176772A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL183056A0 (en) | 2007-10-31 |
| RU2007121707A (ru) | 2008-12-20 |
| EP1809289A1 (en) | 2007-07-25 |
| WO2006053161A8 (en) | 2006-09-14 |
| MX2007005367A (es) | 2007-06-18 |
| AU2005304421A1 (en) | 2006-05-18 |
| ZA200703697B (en) | 2008-09-25 |
| US20060111361A1 (en) | 2006-05-25 |
| SG156681A1 (en) | 2009-11-26 |
| US20090176772A1 (en) | 2009-07-09 |
| CN101072562A (zh) | 2007-11-14 |
| WO2006053161A1 (en) | 2006-05-18 |
| KR20070084063A (ko) | 2007-08-24 |
| CA2586840A1 (en) | 2006-05-18 |
| JP2008519770A (ja) | 2008-06-12 |
| BRPI0517650A (pt) | 2008-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |