[go: up one dir, main page]

NO20071372L - Nye polymorfer av azabisykloheksan - Google Patents

Nye polymorfer av azabisykloheksan

Info

Publication number
NO20071372L
NO20071372L NO20071372A NO20071372A NO20071372L NO 20071372 L NO20071372 L NO 20071372L NO 20071372 A NO20071372 A NO 20071372A NO 20071372 A NO20071372 A NO 20071372A NO 20071372 L NO20071372 L NO 20071372L
Authority
NO
Norway
Prior art keywords
polymorphic
forms
azabicyclohexane
new polymorphs
polymorphic form
Prior art date
Application number
NO20071372A
Other languages
English (en)
Inventor
Kevin John Halloran
Eric J Hagen
Original Assignee
Dov Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dov Pharmaceutical Inc filed Critical Dov Pharmaceutical Inc
Publication of NO20071372L publication Critical patent/NO20071372L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Oppfinnelsen tilveiebringer polymorfe krystallinske former av syreaddisjonssalter av (+)-1-(3,4diklorfenyl)-3-azabisyklo[3.1.0]heksan betegnet den polymorfe form A, den polymorfe form B og den polymorfe form C, hvor den polymorfe form A er mer termodynamisk stabil enn de andre formene, fremgangsmåter for fremstilling og anvendelse av slike polymorfe former og farmasøytiske preparater som inneholder slike polymorfe former.
NO20071372A 2004-08-18 2007-03-14 Nye polymorfer av azabisykloheksan NO20071372L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92074804A 2004-08-18 2004-08-18
PCT/US2005/029420 WO2006023659A2 (en) 2004-08-18 2005-08-17 Novel polymorphs of azabicyclohexane

Publications (1)

Publication Number Publication Date
NO20071372L true NO20071372L (no) 2007-05-18

Family

ID=35968183

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071372A NO20071372L (no) 2004-08-18 2007-03-14 Nye polymorfer av azabisykloheksan

Country Status (14)

Country Link
EP (1) EP1786417A4 (no)
JP (1) JP2008510715A (no)
KR (3) KR20130108489A (no)
CN (1) CN101052393A (no)
AU (1) AU2005277351A1 (no)
BR (1) BRPI0515193A (no)
CA (1) CA2619817A1 (no)
IL (1) IL181185A (no)
MX (1) MX2007001827A (no)
NO (1) NO20071372L (no)
NZ (1) NZ589033A (no)
RU (1) RU2007109817A (no)
WO (1) WO2006023659A2 (no)
ZA (1) ZA200701570B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
EP1915146A4 (en) 2005-07-27 2010-06-02 Dov Pharmaceutical Inc NOVEL 1-ARYL-3-AZABICYCLO [3.1.0] HEXANEES. PREPARATION AND USE FOR THE TREATMENT OF NEUROPSYCHIATRIC DISEASES
US20080045725A1 (en) * 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
EP2646019A4 (en) * 2010-12-03 2014-05-21 Euthymic Bioscience Inc PREPARATION AND USE OF (+) - 1- (3,4-DICHLOROPHENYL) -3-AZABICYCLO- [3.1.0] HEXANE IN THE TREATMENT OF DISEASES AFFECTED BY MONOAMINE-TYPE NEUROTRANSMITTERS
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
JP2016518406A (ja) * 2013-05-07 2016-06-23 ユーシミクス・バイオサイエンス・インコーポレイテッドＥｕｔｈｙｍｉｃｓ Ｂｉｏｓｃｉｅｎｃｅ，Ｉｎｃ． 嗜癖障害およびアルコール関連障害を治療するための（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］へキサンの使用
KR101567003B1 (ko) 2013-12-27 2015-11-06 경희대학교 산학협력단 골편 고정장치 및 골편 절단을 위한 드릴 어셈블리
LT3597189T (lt) 2015-06-17 2022-07-11 Otsuka America Pharmaceutical, Inc. Kristaliniai junginia
CN116813547A (zh) * 2023-06-29 2023-09-29 爱斯特（成都）生物制药股份有限公司 一种制备3-氮杂双环[3，2，1]辛烷盐酸盐的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435419A (en) * 1981-07-01 1984-03-06 American Cyanamid Company Method of treating depression using azabicyclohexanes
US6372919B1 (en) * 2001-01-11 2002-04-16 Dov Pharmaceutical, Inc. (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent

Also Published As

Publication number Publication date
WO2006023659A3 (en) 2006-12-07
EP1786417A4 (en) 2009-05-20
AU2005277351A1 (en) 2006-03-02
KR20130004370A (ko) 2013-01-09
KR20130108489A (ko) 2013-10-02
IL181185A (en) 2012-10-31
EP1786417A2 (en) 2007-05-23
NZ589033A (en) 2012-06-29
CN101052393A (zh) 2007-10-10
RU2007109817A (ru) 2008-09-27
BRPI0515193A (pt) 2008-07-08
JP2008510715A (ja) 2008-04-10
CA2619817A1 (en) 2006-03-02
ZA200701570B (en) 2008-08-27
MX2007001827A (es) 2007-04-23
KR20070054208A (ko) 2007-05-28
IL181185A0 (en) 2007-07-04
WO2006023659A2 (en) 2006-03-02

Similar Documents

Publication Publication Date Title
NO20071372L (no) Nye polymorfer av azabisykloheksan
MXPA05009969A (es) Metodo para aislar la forma cristalina i de la 5-azacitidina.
DK1427411T3 (da) -(-)-1-(3,4-dichlorphenyl)-3-azabicyclo[3.1.0]hexan, præparater deraf og anvendelser som dopamingenoptagelsesinhibitor
NO20074874L (no) Amorf lerkanidipinhydroklorid
TW200510277A (en) Crystalline form of β2-adrenergic receptor agonist
ATE433447T1 (de) Pyrimiidinverbindungen
NO20051008L (no) Nye imidazolforbindelser som transformerende vekst faktor (TGF) inhibitorer
NO20061406L (no) Organiske forbindelser
MX2010009752A (es) Compuestos de oxadiazoantraceno para el tratamiento de diabetes.
NO20063748L (no) Kinolinderivater og anvendelse derav som mykobakterielle inhibitorer
SE0200920D0 (sv) Novel compounds
EA201000050A1 (ru) Замещенные бициклолактамные соединения
CY1109998T1 (el) Ενδυναμωτες υποδοχεων γλουταμινικου
CO5611065A2 (es) Difluorometiltiazolilcarboxanilidas
UA85576C2 (ru) Тетразольные соединения и их применение в качестве метаботропических антагонистов рецепторов глутамата
NO20055568L (no) Substituerte 1,4-diazepiner og anvendelser derav
MEP21908A (en) Polymorphous form of rimonabant, preparation method and pharmaceutical compositions containing same
NO20052676L (no) Polymorfer av bicifadin-saltsyre
SE0300119D0 (sv) Novel compounds
NO20076145L (no) Ureadeviater, fremgangsmater for deres fremstilling og anvendelse derav
TW200420541A (en) Crystalline forms
EA200601194A1 (ru) Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором
NO20045469L (no) (S)-4-amino-5-klor-2-metoksy-N-[I-[ 1-(2-tetrahydrofurylkarbonyl)-4-piperidinylmetyl]-4-piperidinyl]benzamid, fremgangsmate for fremstilling, farmasoytiske sammensetninger inneholdende denne og intermediater derav
DE602004008959D1 (de) Benzoäbüä1,4üdioxepinderivate
SE0200919D0 (sv) Chemical compounds

Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: EUTHYMICS BIOSCIENCE, UA

FC2A Withdrawal, rejection or dismissal of laid open patent application