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NO20071707L - Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner - Google Patents

Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner

Info

Publication number
NO20071707L
NO20071707L NO20071707A NO20071707A NO20071707L NO 20071707 L NO20071707 L NO 20071707L NO 20071707 A NO20071707 A NO 20071707A NO 20071707 A NO20071707 A NO 20071707A NO 20071707 L NO20071707 L NO 20071707L
Authority
NO
Norway
Prior art keywords
pyrid
pyrazolo
dihydro
preparation
phenylhydrazines
Prior art date
Application number
NO20071707A
Other languages
English (en)
Inventor
Bang-Chi Chen
Rulin Zhao
Huiping Zhang
Bei Wang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20071707L publication Critical patent/NO20071707L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Det beskrives en ny fremgangsmåte, og mellomprodukter derav, for fremstilling av 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-oner representert ved formel (I), så vel som de tilsvarende pyrazoler, fra passende fenylhydraziner. (I) Disse forbindelser kan være anvendelige som faktor Xa-hemmere. ?? ?? ?? ?? 1
NO20071707A 2004-09-28 2007-03-30 Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner NO20071707L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61394304P 2004-09-28 2004-09-28
US11/234,942 US20060069085A1 (en) 2004-09-28 2005-09-26 Preparation of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
PCT/US2005/034551 WO2006135425A2 (en) 2004-09-28 2005-09-27 Preparation of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

Publications (1)

Publication Number Publication Date
NO20071707L true NO20071707L (no) 2007-05-25

Family

ID=36100089

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071707A NO20071707L (no) 2004-09-28 2007-03-30 Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner

Country Status (5)

Country Link
US (1) US20060069085A1 (no)
EP (1) EP1805179A2 (no)
JP (1) JP2008514713A (no)
NO (1) NO20071707L (no)
WO (1) WO2006135425A2 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI331526B (en) * 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
TW200303201A (en) * 2001-12-10 2003-09-01 Bristol Myers Squibb Co Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
US20070203178A1 (en) * 2004-09-28 2007-08-30 Malley Mary F Crystalline solvates of apixaban
US7304157B2 (en) * 2004-09-28 2007-12-04 Bristol-Myers Squibb Company Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
WO2006065853A2 (en) * 2004-12-15 2006-06-22 Bristol-Myers Squibb Company Crystalline forms of a factor xa inhibitor
SMT202000093T1 (it) 2009-06-16 2020-03-13 Pfizer Forme di dosaggio di apixaban
US8440693B2 (en) 2009-12-22 2013-05-14 Novartis Ag Substituted isoquinolinones and quinazolinones
EP2785717B1 (en) 2011-11-29 2016-01-13 Novartis AG Pyrazolopyrrolidine compounds
US8815926B2 (en) 2012-01-26 2014-08-26 Novartis Ag Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases
WO2013175417A1 (en) 2012-05-24 2013-11-28 Novartis Ag Pyrrolopyrrolidinone compounds
WO2014115077A1 (en) 2013-01-22 2014-07-31 Novartis Ag Substituted purinone compounds
EP2948453B1 (en) 2013-01-22 2017-08-02 Novartis AG Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction
US8975417B2 (en) 2013-05-27 2015-03-10 Novartis Ag Pyrazolopyrrolidine derivatives and their use in the treatment of disease
MX2015016344A (es) 2013-05-27 2016-03-01 Novartis Ag Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades.
KR20160012195A (ko) 2013-05-28 2016-02-02 노파르티스 아게 Bet 억제제로서의 피라졸로-피롤리딘-4-온 유도체 및 질환의 치료에서의 그의 용도
BR112015029353A2 (pt) 2013-05-28 2017-07-25 Novartis Ag derivados de pirazolo-pirrolidin-4-ona e seu uso no tratamento de doenças
AU2014351413B2 (en) 2013-11-21 2017-06-01 Novartis Ag Pyrrolopyrrolone derivatives and their use as BET inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000039131A1 (en) * 1998-12-23 2000-07-06 Du Pont Pharmaceuticals Company Nitrogen containing heterobicycles as factor xa inhibitors
TWI331526B (en) * 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
SI1427415T1 (sl) * 2001-09-21 2009-12-31 Bristol Myers Squibb Co Sestavine, ki vsebujejo laktame in njihovi derivati kot inhibitorji faktorja xa
TW200302225A (en) * 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
TW200303201A (en) * 2001-12-10 2003-09-01 Bristol Myers Squibb Co Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
US7304157B2 (en) * 2004-09-28 2007-12-04 Bristol-Myers Squibb Company Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US7396932B2 (en) * 2004-09-28 2008-07-08 Bristol-Myers Squibb Company Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

Also Published As

Publication number Publication date
JP2008514713A (ja) 2008-05-08
EP1805179A2 (en) 2007-07-11
US20060069085A1 (en) 2006-03-30
WO2006135425A3 (en) 2007-02-22
WO2006135425A2 (en) 2006-12-21

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