[go: up one dir, main page]

NO20071618L - Fremgangsmate for screening av antistoffbibliotek - Google Patents

Fremgangsmate for screening av antistoffbibliotek

Info

Publication number
NO20071618L
NO20071618L NO20071618A NO20071618A NO20071618L NO 20071618 L NO20071618 L NO 20071618L NO 20071618 A NO20071618 A NO 20071618A NO 20071618 A NO20071618 A NO 20071618A NO 20071618 L NO20071618 L NO 20071618L
Authority
NO
Norway
Prior art keywords
target groups
members
library
antibody library
screening antibody
Prior art date
Application number
NO20071618A
Other languages
English (en)
Inventor
Marike Josee Janneke G Stassar
Herald Reiersen
Original Assignee
Affitech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affitech As filed Critical Affitech As
Publication of NO20071618L publication Critical patent/NO20071618L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Semiconductor Lasers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer en forbedret fremgangsmåte for screening av et bibliotek av molekyler for å identifisere eller selektere én eller flere medlemmer derav som er kandidat bindingspartnere for én eller flere mål-grupper omfattende: (a) kontakte et ekspresjonsbibliotek med én eller flere mål-grupper; (b) underlegge nevnte mål-grupper minst ett vasketrinn; (c) separere mål-grupper som har blitt bundet til én eller flere medlemmer av ekspresjonsbiblioteket fra ubundne medlemmer av ekspresjonsbiblioteket ved separasjon gjennom en organisk fase, for derved å separere kandidat bindingspartnere for nevnte mål-grupper fra andre medlemmer av biblioteket.
NO20071618A 2004-10-08 2007-03-27 Fremgangsmate for screening av antistoffbibliotek NO20071618L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0422431.7A GB0422431D0 (en) 2004-10-08 2004-10-08 Method
PCT/GB2005/003866 WO2006038022A1 (en) 2004-10-08 2005-10-07 Methods for antibody library screening

Publications (1)

Publication Number Publication Date
NO20071618L true NO20071618L (no) 2007-06-27

Family

ID=33443626

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071618A NO20071618L (no) 2004-10-08 2007-03-27 Fremgangsmate for screening av antistoffbibliotek

Country Status (21)

Country Link
US (1) US20090081190A1 (no)
EP (1) EP1800133B1 (no)
JP (1) JP4564062B2 (no)
CN (1) CN101052879B (no)
AT (1) ATE495446T1 (no)
AU (1) AU2005291012B2 (no)
BR (1) BRPI0516546A (no)
CA (1) CA2580080C (no)
DE (1) DE602005025901D1 (no)
DK (1) DK1800133T3 (no)
ES (1) ES2359724T3 (no)
GB (1) GB0422431D0 (no)
HR (1) HRP20110234T1 (no)
IL (1) IL181927A (no)
NO (1) NO20071618L (no)
NZ (1) NZ554076A (no)
PL (1) PL1800133T3 (no)
RU (1) RU2402777C2 (no)
SI (1) SI1800133T1 (no)
WO (1) WO2006038022A1 (no)
ZA (1) ZA200702527B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2698343C (en) * 2007-09-04 2018-06-12 The Regents Of The University Of California High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
US9079942B2 (en) * 2009-02-09 2015-07-14 Epitomics, Inc. CDR-anchored amplification method
US20100317539A1 (en) * 2009-06-12 2010-12-16 Guo-Liang Yu Library of Engineered-Antibody Producing Cells
US8293483B2 (en) * 2009-09-11 2012-10-23 Epitomics, Inc. Method for identifying lineage-related antibodies
WO2012058334A1 (en) * 2010-10-26 2012-05-03 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Morphology & protein specific reagents as diagnostics for neurodegenerative diseases
GB201116364D0 (en) * 2011-09-22 2011-11-02 Bioinvent Int Ab Screening methods and uses thereof
SG11201404991YA (en) * 2012-02-23 2014-09-26 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
EP2786147B1 (en) * 2012-12-04 2017-02-01 Scinopharm Taiwan Ltd. Method for selecting a pool of molecules
RU2560699C2 (ru) * 2013-08-02 2015-08-20 федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский ядерный университет МИФИ" (НИЯУ МИФИ) Способ создания наноразмерной диагностической метки на основе конъюгатов наночастиц и однодоменных антител
GB201420852D0 (en) * 2014-11-24 2015-01-07 Genevillage Kft Method
RU2618872C1 (ru) * 2015-12-09 2017-05-11 Федеральное бюджетное учреждение науки Государственный научный центр прикладной микробиологии и биотехнологии (ФБУН ГНЦ ПМБ) Способ направленного истощения олигонуклеотидных библиотек для снижения неспецифической адсорбции при твердофазной селекции аптамеров на основе нуклеиновых кислот
US10526598B2 (en) * 2018-04-24 2020-01-07 Inscripta, Inc. Methods for identifying T-cell receptor antigens
WO2020216191A1 (zh) 2019-04-22 2020-10-29 泷搌（上海）生物科技有限公司 制备噬菌体文库的方法
KR102301987B1 (ko) * 2019-11-14 2021-09-13 연세대학교 산학협력단 항체 선별 방법, 박테리아 오염 진단 방법 및 박테리아 오염 진단 키트

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5492807A (en) * 1993-11-19 1996-02-20 Santi; Daniel V. Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease
US6255455B1 (en) * 1996-10-11 2001-07-03 The Trustees Of The University Of Pennsylvania Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof
TW585921B (en) * 1997-07-10 2004-05-01 Res Dev Foundation Species specific monoclonal antibodies and phage displayed Fab and scFV fragments for fragments for targeted destruction of imported fire ants
RU2184780C2 (ru) * 2000-08-09 2002-07-10 Государственный научный центр вирусологии и биотехнологии "Вектор" ПЕПТИД-ИМИТАТОР ЭПИТОПА БЕЛКА gp120 ВИЧ-1
US6235686B1 (en) * 2000-08-16 2001-05-22 R.T. Vanderbilt Company, Inc. Lubricating compositions containing aromatized 1,2-dihydro-2,2,4-trimethylquinoline polymers
US20040170955A1 (en) * 2000-09-08 2004-09-02 Wadih Arap Human and mouse targeting peptides identified by phage display
EP1315840A4 (en) * 2000-09-08 2005-11-02 Univ Texas BIOPANNING AND RAPID ANALYSIS OF SELECTIVE INTERACTIVE LIGANDS (BRASIL)
US7420030B2 (en) * 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
US20040048243A1 (en) * 2001-09-07 2004-03-11 Wadih Arap Methods and compositions for in vitro targeting

Also Published As

Publication number Publication date
EP1800133A1 (en) 2007-06-27
US20090081190A1 (en) 2009-03-26
ATE495446T1 (de) 2011-01-15
IL181927A (en) 2011-09-27
AU2005291012A1 (en) 2006-04-13
CA2580080A1 (en) 2006-04-13
HRP20110234T1 (hr) 2011-05-31
DK1800133T3 (da) 2011-03-28
ZA200702527B (en) 2008-11-26
IL181927A0 (en) 2007-07-04
NZ554076A (en) 2009-12-24
RU2402777C2 (ru) 2010-10-27
ES2359724T3 (es) 2011-05-26
BRPI0516546A (pt) 2008-09-09
RU2007117144A (ru) 2008-11-20
AU2005291012B2 (en) 2011-04-14
GB0422431D0 (en) 2004-11-10
SI1800133T1 (sl) 2011-06-30
CN101052879B (zh) 2012-07-25
WO2006038022A1 (en) 2006-04-13
DE602005025901D1 (de) 2011-02-24
CA2580080C (en) 2012-09-18
HK1105450A1 (en) 2008-02-15
EP1800133B1 (en) 2011-01-12
JP2008516220A (ja) 2008-05-15
JP4564062B2 (ja) 2010-10-20
PL1800133T3 (pl) 2011-06-30
CN101052879A (zh) 2007-10-10

Similar Documents

Publication Publication Date Title
NO20071618L (no) Fremgangsmate for screening av antistoffbibliotek
Stein Mass spectral reference libraries: an ever-expanding resource for chemical identification
Nesper et al. A novel capture compound for the identification and analysis of cyclic di-GMP binding proteins
Cho et al. Application of saturates, aromatics, resins, and asphaltenes crude oil fractionation for detailed chemical characterization of heavy crude oils by Fourier transform ion cyclotron resonance mass spectrometry equipped with atmospheric pressure photoionization
Rathsack et al. Analysis of high molecular compounds in pyrolysis liquids from a german brown coal by FT-ICR-MS
WO2010119261A8 (en) Method for quantifying modified peptides
NZ607750A (en) Purification of antibodies using simulated moving bed chromatography
Cole et al. Molecular characterization of nitrogen-containing species in switchgrass bio-oils at various harvest times
NZ584684A (en) A method for characterization of a recombinant polyclonal protein
Becker et al. Rapid and simultaneous analysis of three molecular sea surface temperature proxies and application to sediments from the Sea of Marmara
DE602006006200D1 (de) Antikörper gegen 25-hydroxyvitamin d
Kovalchik et al. Standard method design considerations for semi-quantification of total naphthenic acids in oil sands process affected water by mass spectrometry: A review
Dayon et al. Proteomics of human plasma: A critical comparison of analytical workflows in terms of effort, throughput and outcome
AU2018274704A1 (en) Assay for plasma cell associated disease
Patrick et al. Differentiating sulfopeptide and phosphopeptide ions via resonant infrared photodissociation
Luczak et al. Optimization of plasma sample pretreatment for quantitative analysis using iTRAQ labeling and LC-MALDI-TOF/TOF
WO2018167141A3 (en) Target detection using a monovalent antibody
NO20075285L (no) Fremgangsmate for a bestemme og kontrollere dannelsen av avsetninger i et vannsystem
Battistini et al. Proteomic analysis by mass spectrometry of postmortem muscle protein degradation for PMI estimation: A pilot study
WO2009011426A1 (ja) γ-セクレターゼの新規基質c-Metを利用したスクリーニング方法
WO2009064006A1 (ja) γ-セクレターゼの新規基質EphA7を利用したスクリーニング方法
Asada et al. Isomeric discrimination of synthetic cannabinoids by GC‐EI‐MS: 1‐adamantyl and 2‐adamantyl isomers of N‐adamantyl carboxamides
BR112021020760A2 (pt) Método de predição de produtividade de soja
Bischoff et al. Genomic variability and protein species—Improving sequence coverage for proteogenomics
US20150219616A1 (en) Systems for quantitation of naphthenic acids in water and crude oil

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application