NO20070502L - Azaindoles useful as inhibitors of protein kinases - Google Patents
Azaindoles useful as inhibitors of protein kinasesInfo
- Publication number
- NO20070502L NO20070502L NO20070502A NO20070502A NO20070502L NO 20070502 L NO20070502 L NO 20070502L NO 20070502 A NO20070502 A NO 20070502A NO 20070502 A NO20070502 A NO 20070502A NO 20070502 L NO20070502 L NO 20070502L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- protein kinases
- azaindoles
- useful
- azaindoles useful
- Prior art date
Links
- 102000001253 Protein Kinase Human genes 0.000 title abstract 2
- 125000005334 azaindolyl group Chemical group N1N=C(C2=CC=CC=C12)* 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 108060006633 protein kinase Proteins 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Foreliggende oppfinnelse vedrører azaindoler (I) som er nyttige som inhibitorer av proteinkinaser. Oppfinnelsen tilveiebringer også farmasøytisk akseptable sammensetninger omfattende nevnte forbindelser og metoder for å anvende sammensetningene i behandlingen av forskjellige sykdommer, tilstander eller forstyrrelser. Oppfinnelsen tilveiebringer også fremgangsmåter for å fremstille forbindelsene ifølge oppfinnelsen.The present invention relates to azaindoles (I) which are useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods for using the compositions in the treatment of various diseases, conditions or disorders. The invention also provides methods for preparing the compounds of the invention.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58438304P | 2004-06-30 | 2004-06-30 | |
| US58472104P | 2004-07-01 | 2004-07-01 | |
| PCT/US2005/011358 WO2005103050A2 (en) | 2004-04-02 | 2005-04-04 | Azaindoles useful as inhibitors of rock and other protein kinases |
| US11/098,751 US7514448B2 (en) | 2004-04-02 | 2005-04-04 | Azaindoles useful as inhibitors of rock and other protein kinases |
| PCT/US2005/023429 WO2006004984A1 (en) | 2004-06-30 | 2005-06-29 | Azaindoles useful as inhibitors of protein kinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20070502L true NO20070502L (en) | 2007-01-26 |
Family
ID=37801682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20070502A NO20070502L (en) | 2004-06-30 | 2007-01-26 | Azaindoles useful as inhibitors of protein kinases |
Country Status (4)
| Country | Link |
|---|---|
| JP (2) | JP5122280B2 (en) |
| IL (1) | IL180303A0 (en) |
| MX (1) | MX2007000092A (en) |
| NO (1) | NO20070502L (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5122280B2 (en) * | 2004-06-30 | 2013-01-16 | バーテックス ファーマシューティカルズ インコーポレイテッド | Azaindoles useful as inhibitors of protein kinases |
| AU2005272815A1 (en) * | 2004-08-13 | 2006-02-23 | Genentech, Inc. | Thiazole based inhibitors of ATP-utilizing enzymes |
| DE102008038221A1 (en) * | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | 7-azaindole derivatives |
| DE102009058280A1 (en) * | 2009-12-14 | 2011-06-16 | Merck Patent Gmbh | thiazole |
| RU2603008C2 (en) | 2010-04-16 | 2016-11-20 | Ац Иммуне С.А. | New compounds for treating diseases, associated with amyloid or amyloid-like proteins |
| US8623869B2 (en) * | 2010-06-23 | 2014-01-07 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
| DE102011105469A1 (en) * | 2011-06-24 | 2012-12-27 | Merck Patent Gmbh | 7-azaindole derivatives |
| BR112014029868A2 (en) * | 2012-05-31 | 2017-06-27 | Phenex Pharmaceuticals Ag | compounds and pharmaceutical composition |
| PL3070086T3 (en) | 2014-02-04 | 2019-04-30 | Taiho Pharmaceutical Co Ltd | Azaindole derivative |
| JP2023545219A (en) * | 2020-10-05 | 2023-10-26 | エンライブン インコーポレイテッド | 7-Azaindole Compounds for Inhibition of BCR-ABL Tyrosine Kinase |
| WO2023110843A1 (en) * | 2021-12-15 | 2023-06-22 | Almirall, S.A. | Heterobicyclic derivatives as itk inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6265403B1 (en) * | 1999-01-20 | 2001-07-24 | Merck & Co., Inc. | Angiogenesis inhibitors |
| EP1261607B1 (en) * | 2000-03-01 | 2008-11-12 | Janssen Pharmaceutica N.V. | 2,4-disubstituted thiazolyl derivatives |
| SE0202463D0 (en) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
| MXPA06011328A (en) * | 2004-04-02 | 2006-12-15 | Vertex Pharma | Azaindoles useful as inhibitors of rock and other protein kinases. |
| JP5122280B2 (en) * | 2004-06-30 | 2013-01-16 | バーテックス ファーマシューティカルズ インコーポレイテッド | Azaindoles useful as inhibitors of protein kinases |
-
2005
- 2005-06-29 JP JP2007519460A patent/JP5122280B2/en not_active Expired - Fee Related
- 2005-06-29 MX MX2007000092A patent/MX2007000092A/en active IP Right Grant
-
2006
- 2006-12-25 IL IL180303A patent/IL180303A0/en unknown
-
2007
- 2007-01-26 NO NO20070502A patent/NO20070502L/en not_active Application Discontinuation
-
2011
- 2011-10-14 JP JP2011227135A patent/JP2012012417A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008513352A (en) | 2008-05-01 |
| JP5122280B2 (en) | 2013-01-16 |
| MX2007000092A (en) | 2007-03-07 |
| IL180303A0 (en) | 2007-06-03 |
| JP2012012417A (en) | 2012-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |