NO20065078L - Inhalation powder formulations containing enantiomerically pure beta agonists. - Google Patents
Inhalation powder formulations containing enantiomerically pure beta agonists.Info
- Publication number
- NO20065078L NO20065078L NO20065078A NO20065078A NO20065078L NO 20065078 L NO20065078 L NO 20065078L NO 20065078 A NO20065078 A NO 20065078A NO 20065078 A NO20065078 A NO 20065078A NO 20065078 L NO20065078 L NO 20065078L
- Authority
- NO
- Norway
- Prior art keywords
- enantiomerically pure
- powder formulations
- formulations containing
- beta agonists
- inhalation powder
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000000843 powder Substances 0.000 title abstract 2
- 229940125388 beta agonist Drugs 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Foreliggende oppfinnelse angår pulverformuleringer for inhalering inneholdende enantiomerisk rene forbindelser med den geneelle formel 1 hvor gruppene R1, R2, R3 og R4 kan ha betydningene angitt i kravene og i beskrivelsen, eventuelt i form av de farmasøytisk akseptable syreaddisjonssalter derav, samt eventuelt i kombinasjon med et farmasøytisk akseptabelt tilsetningsmiddel, fremgangsmåter for fremstilling av dem og anvendelse av dem som farmasøytiske preparater, spesielt som farmasøytiske preparater for behandling av respiratoriske lidelser.The present invention relates to powder formulations for inhalation containing enantiomerically pure compounds of the general formula 1 wherein the groups R1, R2, R3 and R4 may have the meanings set forth in the claims and in the specification, optionally in the form of the pharmaceutically acceptable acid addition salts thereof, and optionally in combination with a pharmaceutically acceptable additives, methods of preparing them and using them as pharmaceutical preparations, especially as pharmaceutical preparations for the treatment of respiratory disorders.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004024451A DE102004024451A1 (en) | 2004-05-14 | 2004-05-14 | Powder formulations for inhalation containing enantiomerically pure beta agonists |
| PCT/EP2005/005078 WO2005110359A1 (en) | 2004-05-14 | 2005-05-11 | Inhalation powder formulations containing enantiomerically pure beta-agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20065078L true NO20065078L (en) | 2006-11-28 |
Family
ID=35058202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20065078A NO20065078L (en) | 2004-05-14 | 2006-11-03 | Inhalation powder formulations containing enantiomerically pure beta agonists. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1809236B1 (en) |
| JP (1) | JP4891899B2 (en) |
| KR (1) | KR101270449B1 (en) |
| CN (1) | CN1984638A (en) |
| AR (1) | AR048899A1 (en) |
| AU (1) | AU2005244424B2 (en) |
| BR (1) | BRPI0511136A (en) |
| CA (1) | CA2565915C (en) |
| DE (1) | DE102004024451A1 (en) |
| DK (1) | DK1809236T3 (en) |
| EA (1) | EA012582B1 (en) |
| ES (1) | ES2401786T3 (en) |
| IL (1) | IL179215A (en) |
| MX (1) | MXPA06013221A (en) |
| MY (1) | MY145838A (en) |
| NO (1) | NO20065078L (en) |
| PE (1) | PE20060239A1 (en) |
| PL (1) | PL1809236T3 (en) |
| SG (1) | SG152258A1 (en) |
| TW (1) | TW200607508A (en) |
| UA (1) | UA86807C2 (en) |
| UY (1) | UY28896A1 (en) |
| WO (1) | WO2005110359A1 (en) |
| ZA (1) | ZA200607785B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004024452A1 (en) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for the inhalation of beta agonists |
| GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
| RU2442771C2 (en) | 2005-08-08 | 2012-02-20 | Арджента Дискавери Лтд | Derivants of bicyclo[2, 2, 1] hept-7-ylamine and their applications |
| CN101208316B (en) | 2005-08-15 | 2012-05-09 | 贝林格尔·英格海姆国际有限公司 | Method for preparing beta-mimetics |
| US8236786B2 (en) | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
| WO2010076553A1 (en) | 2008-12-30 | 2010-07-08 | Dr. Reddy's Laboratories Ltd | Sulfonamide compounds for the treatment of respiratory disorders |
| WO2010150014A1 (en) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
| GB0918923D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminothiazole derivatives |
| GB0918924D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Azaindole derivatives |
| GB0918922D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminopyridine derivatives |
| WO2011098746A1 (en) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone |
| GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
| GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
| WO2014056840A1 (en) | 2012-10-09 | 2014-04-17 | Boehringer Ingelheim International Gmbh | Beta-2-adrenoceptor agonist for the treatment of cough |
| JP2019536812A (en) | 2016-12-12 | 2019-12-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Nintedanib for use in methods of treating interstitial lung disease by co-administration with olodaterol |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3134590A1 (en) * | 1981-09-01 | 1983-03-10 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW BENZO HETEROCYCLES |
| US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
| DE4318455A1 (en) | 1993-06-03 | 1994-12-08 | Boehringer Ingelheim Kg | Capsule holder |
| NZ522677A (en) * | 2000-04-27 | 2004-10-29 | Boehringer Ingelheim Pharma | Novel, slow-acting betamimetics, a method for their production and their use as medicaments |
| GB0107106D0 (en) * | 2001-03-21 | 2001-05-09 | Boehringer Ingelheim Pharma | Powder inhaler formulations |
| DE10141377A1 (en) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Scattering process for the production of powder formulations |
| DE10212264A1 (en) | 2002-03-20 | 2003-10-02 | Boehringer Ingelheim Pharma | Crystalline micronisate, process for its preparation and its use for the manufacture of a medicament |
| UA80123C2 (en) | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
| DE10253282A1 (en) * | 2002-11-15 | 2004-05-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Treatment of chronic obstructive pulmonary disease, using new or known N-substituted 2-amino-1-(benz-(1,4)-oxazin-3-on-8-yl)-ethanol derivative beta-mimetic agents, suitable for once-daily administration |
-
2004
- 2004-05-14 DE DE102004024451A patent/DE102004024451A1/en not_active Withdrawn
-
2005
- 2005-05-11 EA EA200602016A patent/EA012582B1/en not_active IP Right Cessation
- 2005-05-11 DK DK05747562.6T patent/DK1809236T3/en active
- 2005-05-11 KR KR1020067026352A patent/KR101270449B1/en not_active Expired - Fee Related
- 2005-05-11 CN CNA2005800154329A patent/CN1984638A/en active Pending
- 2005-05-11 JP JP2007512080A patent/JP4891899B2/en not_active Expired - Lifetime
- 2005-05-11 EP EP05747562A patent/EP1809236B1/en not_active Expired - Lifetime
- 2005-05-11 ES ES05747562T patent/ES2401786T3/en not_active Expired - Lifetime
- 2005-05-11 UA UAA200612950A patent/UA86807C2/en unknown
- 2005-05-11 SG SG200902738-4A patent/SG152258A1/en unknown
- 2005-05-11 AU AU2005244424A patent/AU2005244424B2/en not_active Ceased
- 2005-05-11 PL PL05747562T patent/PL1809236T3/en unknown
- 2005-05-11 BR BRPI0511136-6A patent/BRPI0511136A/en not_active IP Right Cessation
- 2005-05-11 WO PCT/EP2005/005078 patent/WO2005110359A1/en not_active Ceased
- 2005-05-11 MX MXPA06013221A patent/MXPA06013221A/en active IP Right Grant
- 2005-05-11 CA CA2565915A patent/CA2565915C/en not_active Expired - Fee Related
- 2005-05-12 UY UY28896A patent/UY28896A1/en not_active Application Discontinuation
- 2005-05-12 MY MYPI20052155A patent/MY145838A/en unknown
- 2005-05-12 PE PE2005000530A patent/PE20060239A1/en not_active Application Discontinuation
- 2005-05-13 TW TW094115490A patent/TW200607508A/en unknown
- 2005-05-13 AR ARP050101958A patent/AR048899A1/en unknown
-
2006
- 2006-09-18 ZA ZA200607785A patent/ZA200607785B/en unknown
- 2006-11-03 NO NO20065078A patent/NO20065078L/en not_active Application Discontinuation
- 2006-11-13 IL IL179215A patent/IL179215A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW200607508A (en) | 2006-03-01 |
| BRPI0511136A (en) | 2007-11-27 |
| DE102004024451A1 (en) | 2005-12-22 |
| MXPA06013221A (en) | 2007-02-08 |
| EP1809236A1 (en) | 2007-07-25 |
| KR101270449B1 (en) | 2013-06-04 |
| SG152258A1 (en) | 2009-05-29 |
| IL179215A0 (en) | 2007-03-08 |
| AU2005244424A1 (en) | 2005-11-24 |
| CN1984638A (en) | 2007-06-20 |
| JP2007537195A (en) | 2007-12-20 |
| UY28896A1 (en) | 2005-12-30 |
| ZA200607785B (en) | 2008-07-30 |
| AU2005244424B2 (en) | 2010-12-23 |
| UA86807C2 (en) | 2009-05-25 |
| JP4891899B2 (en) | 2012-03-07 |
| EA012582B1 (en) | 2009-10-30 |
| EP1809236B1 (en) | 2012-12-26 |
| AR048899A1 (en) | 2006-06-07 |
| EA200602016A1 (en) | 2007-06-29 |
| PE20060239A1 (en) | 2006-03-27 |
| IL179215A (en) | 2011-04-28 |
| WO2005110359A1 (en) | 2005-11-24 |
| CA2565915C (en) | 2013-12-10 |
| DK1809236T3 (en) | 2013-02-11 |
| KR20070016169A (en) | 2007-02-07 |
| PL1809236T3 (en) | 2013-05-31 |
| ES2401786T3 (en) | 2013-04-24 |
| MY145838A (en) | 2012-04-30 |
| CA2565915A1 (en) | 2005-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |