[go: up one dir, main page]

NO20065850L - Fremgangsmate for identifisering av PDE5-modulatorer - Google Patents

Fremgangsmate for identifisering av PDE5-modulatorer

Info

Publication number
NO20065850L
NO20065850L NO20065850A NO20065850A NO20065850L NO 20065850 L NO20065850 L NO 20065850L NO 20065850 A NO20065850 A NO 20065850A NO 20065850 A NO20065850 A NO 20065850A NO 20065850 L NO20065850 L NO 20065850L
Authority
NO
Norway
Prior art keywords
modulators
pde5
procedure
identifying
domain
Prior art date
Application number
NO20065850A
Other languages
English (en)
Norwegian (no)
Inventor
Tobias Kanacher
Juergen Linder
Joachim Schultz
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of NO20065850L publication Critical patent/NO20065850L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO20065850A 2004-05-28 2006-12-18 Fremgangsmate for identifisering av PDE5-modulatorer NO20065850L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004026717 2004-05-28
DE102005009671 2005-02-28
PCT/EP2005/052269 WO2005116195A2 (fr) 2004-05-28 2005-05-18 Methode d'identification de modulateurs de pde5

Publications (1)

Publication Number Publication Date
NO20065850L true NO20065850L (no) 2006-12-18

Family

ID=35276430

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065850A NO20065850L (no) 2004-05-28 2006-12-18 Fremgangsmate for identifisering av PDE5-modulatorer

Country Status (10)

Country Link
US (1) US20090087871A1 (fr)
EP (1) EP1749093A2 (fr)
JP (1) JP2008500824A (fr)
KR (1) KR20070030221A (fr)
AU (1) AU2005248079A1 (fr)
CA (1) CA2590553A1 (fr)
IL (1) IL179057A0 (fr)
NO (1) NO20065850L (fr)
NZ (1) NZ551240A (fr)
WO (1) WO2005116195A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11241485B2 (en) 2017-06-12 2022-02-08 Obsidian Therapeutics, Inc. PDE5 compositions and methods for immunotherapy
US20220403001A1 (en) 2018-06-12 2022-12-22 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
AU2020345943A1 (en) 2019-09-10 2022-03-31 Obsidian Therapeutics, Inc. CA2-IL15 fusion proteins for tunable regulation
CN115794002A (zh) * 2021-09-09 2023-03-14 华为技术有限公司 会议终端及其控制方法、装置
CN117187343B (zh) * 2023-09-06 2024-11-01 青岛大学 一种磷酸二酯酶抑制剂的高通量筛选方法

Also Published As

Publication number Publication date
WO2005116195A2 (fr) 2005-12-08
IL179057A0 (en) 2007-03-08
AU2005248079A1 (en) 2005-12-08
KR20070030221A (ko) 2007-03-15
CA2590553A1 (fr) 2005-12-08
US20090087871A1 (en) 2009-04-02
NZ551240A (en) 2009-08-28
WO2005116195A3 (fr) 2006-02-16
EP1749093A2 (fr) 2007-02-07
JP2008500824A (ja) 2008-01-17

Similar Documents

Publication Publication Date Title
NO20042964L (no) Spiroazasykliske forbindelser som monoaminreseptormodulatorer
ATE373665T1 (de) Benzo-kondensierte heteroarylamid-derivative von thienopyridinen nützlich als therapeutische agentien, entsprechende pharmazeutische zusammensetzungen, und methoden für ihre verwendung
BRPI0414541B8 (pt) compostos heterocíclicos fundidos tendo atividade de modulação de receptor de serotonina, método de preparação de compostos intermediários
NO20074805L (no) Fremgangsmate for a identifisere PDE11-modulatorer
NO20052888L (no) Diamintriazoler anvendelige som inhibitorer av proteinkinaser
ECSP045081A (es) Derivados de 1,8-naftiridina y su uso para el tratamiento de la diabetes y trastornos relacionados
CA2492096A1 (fr) Derives de 1-h-pyrrolidin-2,4-dione spirocyclique cis-alcoxysubstituee utilises comme insecticides
BR0313176A (pt) Composições de pirazol úteis como inibidores de gsk-3
NO20052524L (no) Aminerte isofiavonoidderivater og anvendelse derav
NO20082023L (no) Pyrrolotriazin kinaseinhibitorer
DK1412357T3 (da) Beta-aminotetrahydroimidazo-(1,2-a)-pyraziner og tetrahydrotriazolo-(4,3-a)-pyraziner som dipeptidylpeptidaseinhibitorer til behandling eller forebyggelse af diabetes
NO20061074L (no) Forbindelser og sammensetninger som inbibitorer av reseptortyrosinkinaseaktivitet
DE60319406D1 (de) Meso-substituierte porphyrine
NO20073628L (no) Pyridoner som er nyttige som inhibitorer av kinaser
MXPA03006093A (es) Derivados de n(fenilsulfonil)glicina y su uso terapeutico.
BRPI0414593A (pt) derivados de ácido sulfonamida substituìda-indol-2-carboxìlico como inibidores de pai-1
NO20061845L (no) Fenyl-piperazinderivater som modulatorer for muskarine reseptorer
CY1110130T1 (el) Παραγωγα μορφολινης για χρηση ως αγωνιστες ντοπαμινης στην θεραπευτικη αγωγη σεξουαλικης δυσλειτουργιας i.α.
DK1456212T3 (da) 6-aminomorphinanderivater, fremgangsmåder til fremstilling heraf og disses anvendelse
NO20054371L (no) Somatostatin-dopamin kimaere analoger
GB0327380D0 (en) Method
DE602005016800D1 (de) Hif-prolylhydroxylase-aktivitätstest
UY28344A1 (es) Nuevos compuestos
NO20065850L (no) Fremgangsmate for identifisering av PDE5-modulatorer
UA96277C2 (en) Benzimidazole derivatives

Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application