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NO20062685L - Fremgangsmate for fremstilling av finkjemikalie ved fermentering - Google Patents

Fremgangsmate for fremstilling av finkjemikalie ved fermentering

Info

Publication number
NO20062685L
NO20062685L NO20062685A NO20062685A NO20062685L NO 20062685 L NO20062685 L NO 20062685L NO 20062685 A NO20062685 A NO 20062685A NO 20062685 A NO20062685 A NO 20062685A NO 20062685 L NO20062685 L NO 20062685L
Authority
NO
Norway
Prior art keywords
lysine
preparation
increasing
fine chemical
provides
Prior art date
Application number
NO20062685A
Other languages
English (en)
Inventor
Burkhard Kroger
Oskar Zelder
Hartwig Schroder
Stefan Hafner
Patrick Kiefer
Christoph Wittmann
Corinna Klopprogge
Elmar Heinzle
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO20062685L publication Critical patent/NO20062685L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Foreliggende oppfinnelse angår fremgangsmåter for å øke produksjonen av et finkjemikalie, for eksempel lysin fra en mikroorganisme, f. eks. Corynebacterium ved deregulering av et enzymkodende gen, dvs. laktat dehydrogenase. I en foretrukket utførelsesform tilveiebringer oppfinnelsen fremgangsmåter for å øke produksjonen av lysin i Corynebacterium glutamicum ved å øke ekspresjon av laktat dehydrogenase-aktivitet. Oppfinnelsen tilveiebringer også en ny fremgangsmåte for fremstilling av lysin ved å regulere karbon fluks mot oksaloacetat (OAA). I en foretrukket utførelsesform tilveiebringer oppfinnelsen fremgangsmåter for fremstilling av lysin ved anvendelse av fruktose eller sukrose som en karbonkilde.
NO20062685A 2003-12-18 2006-06-09 Fremgangsmate for fremstilling av finkjemikalie ved fermentering NO20062685L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB0306435 2003-12-18
PCT/IB2004/004426 WO2005059154A2 (en) 2003-12-18 2004-12-17 Methods for the preparation of a fine chemical by fermentation

Publications (1)

Publication Number Publication Date
NO20062685L true NO20062685L (no) 2006-09-14

Family

ID=34685564

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062685A NO20062685L (no) 2003-12-18 2006-06-09 Fremgangsmate for fremstilling av finkjemikalie ved fermentering

Country Status (12)

Country Link
US (1) US20070134768A1 (no)
EP (1) EP1697532A2 (no)
JP (1) JP2007514436A (no)
KR (1) KR20070026355A (no)
AU (1) AU2004299728A1 (no)
BR (1) BRPI0417773A (no)
CA (1) CA2548125A1 (no)
MX (1) MXPA06006758A (no)
NO (1) NO20062685L (no)
RU (1) RU2006125503A (no)
TW (1) TW200602486A (no)
WO (1) WO2005059154A2 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7326546B2 (en) * 2005-03-10 2008-02-05 Ajinomoto Co., Inc. Purine-derived substance-producing bacterium and a method for producing purine-derived substance
JP5714904B2 (ja) * 2007-09-26 2015-05-07 アーチャー−ダニエルズ−ミッドランド カンパニー Ｃｏｒｙｎｅｂａｃｔｅｒｉｕｍｇｌｕｔａｍｉｃｕｍでのスクロースからのアミノ酸の産生
US20090238920A1 (en) * 2008-03-21 2009-09-24 Lewis Ted C Process for making high grade protein product
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
TWI385596B (en) * 2008-11-12 2013-02-11 Image signal filtering device and the method therefore
BRPI1013426A2 (pt) 2009-04-30 2016-11-08 Genomatica Inc organismos para produção de 1,3-butanodiol
CN109136161A (zh) * 2009-12-10 2019-01-04 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
CN102250764B (zh) * 2010-05-19 2013-06-26 华东理工大学 微型全息式生物传感反应器系统
EP2794852A4 (en) 2011-12-22 2015-09-02 Basf Se METHOD AND RECOMBINANT MICROORGANISMS FOR THE PRODUCTION OF FINE CHEMICALS
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2020208842A1 (ja) * 2019-04-12 2020-10-15 Ｇｒｅｅｎ Ｅａｒｔｈ Ｉｎｓｔｉｔｕｔｅ 株式会社 遺伝子組換え微生物及びこれを用いた目的物質の生産方法
CN110791535A (zh) * 2019-12-02 2020-02-14 齐齐哈尔龙江阜丰生物科技有限公司 一种生产和提取赖氨酸的工艺
KR102433234B1 (ko) * 2020-09-29 2022-08-18 대상 주식회사 L-시트룰린 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-시트룰린의 생산 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4074365B2 (ja) * 1998-01-28 2008-04-09 三菱化学株式会社 ラクテートデヒドロゲナーゼ遺伝子及び該遺伝子破壊株
KR20070087088A (ko) * 1999-06-25 2007-08-27 바스프 악티엔게젤샤프트 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자
DK1208205T3 (da) * 1999-07-23 2007-02-05 Archer Daniels Midland Co Fremgangsmåder til frembringelse af L-aminosyrer ved hjælp af en forögelse af cellulært NADPH
DE10044681A1 (de) * 2000-09-09 2002-03-21 Degussa Neue für das lldD2-Gen kodierende Nukleotidsequenzen
CN101126075B (zh) * 2001-08-06 2012-05-09 赢创德固赛有限公司 生产化合物ⅱ的棒状细菌

Also Published As

Publication number Publication date
EP1697532A2 (en) 2006-09-06
RU2006125503A (ru) 2008-01-27
JP2007514436A (ja) 2007-06-07
BRPI0417773A (pt) 2007-03-20
WO2005059154A3 (en) 2005-10-13
KR20070026355A (ko) 2007-03-08
CA2548125A1 (en) 2005-06-30
WO2005059154A2 (en) 2005-06-30
MXPA06006758A (es) 2007-01-26
US20070134768A1 (en) 2007-06-14
TW200602486A (en) 2006-01-16
AU2004299728A1 (en) 2005-06-30

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