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NO20060719L - Substituerte cykloalkylaminderivater som modulatorer av kemokin reseptor aktivitet - Google Patents

Substituerte cykloalkylaminderivater som modulatorer av kemokin reseptor aktivitet

Info

Publication number
NO20060719L
NO20060719L NO20060719A NO20060719A NO20060719L NO 20060719 L NO20060719 L NO 20060719L NO 20060719 A NO20060719 A NO 20060719A NO 20060719 A NO20060719 A NO 20060719A NO 20060719 L NO20060719 L NO 20060719L
Authority
NO
Norway
Prior art keywords
modulators
chemokine receptor
receptor activity
substituted cycloalkylamine
cycloalkylamine derivatives
Prior art date
Application number
NO20060719A
Other languages
English (en)
Inventor
Douglas Guy Batt
John V Duncia
Daniel S Gardner
Percy H Carter
Robert J Cherney
Michael G Yang
Gregory D Brown
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20060719L publication Critical patent/NO20060719L/no

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    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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Abstract

Foreliggende søknad beskriver modulatorer av MCP-1 med formel (I): eller farmasøytisk akseptable saltformer derav, anvendelige for forhindring av astma, multippel sklerose, arteherosklerose og revmatoid artritt.
NO20060719A 2003-08-21 2006-02-14 Substituerte cykloalkylaminderivater som modulatorer av kemokin reseptor aktivitet NO20060719L (no)

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US10/923,538 US7378409B2 (en) 2003-08-21 2004-08-19 Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
PCT/US2004/027195 WO2005020899A2 (en) 2003-08-21 2004-08-20 Substituted cycloalkyamine derivatives as modulators of chemokine receptor activity

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