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NO20055891L - Kinazolinderivater som aurorakinaseinhibitorer - Google Patents

Kinazolinderivater som aurorakinaseinhibitorer

Info

Publication number
NO20055891L
NO20055891L NO20055891A NO20055891A NO20055891L NO 20055891 L NO20055891 L NO 20055891L NO 20055891 A NO20055891 A NO 20055891A NO 20055891 A NO20055891 A NO 20055891A NO 20055891 L NO20055891 L NO 20055891L
Authority
NO
Norway
Prior art keywords
quinazoline derivatives
aurorakinase
inhibitors
treatment
well
Prior art date
Application number
NO20055891A
Other languages
English (en)
Inventor
Frederic Henri Jung
Andrew Austen Mortlock
Nicola Murdoch Heron
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33522456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20055891(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20055891L publication Critical patent/NO20055891L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Kinazolin-derivater med formel (I) for anvendelse ved behandling av proliferative sykdommer så som kreft, og ved fremstilling av medikamenter for anvendelse ved behandling av proliferative sykdommer, samt fremgangsmåter for fremstilling av dem, så vel som farmasøytiske preparater som inneholder dem som aktiv bestanddel.
NO20055891A 2003-06-17 2005-12-12 Kinazolinderivater som aurorakinaseinhibitorer NO20055891L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03291463 2003-06-17
PCT/GB2004/002564 WO2004113324A1 (en) 2003-06-17 2004-06-14 Chinazoline derivatives as aurora kinase inhibitors

Publications (1)

Publication Number Publication Date
NO20055891L true NO20055891L (no) 2006-02-07

Family

ID=33522456

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055891A NO20055891L (no) 2003-06-17 2005-12-12 Kinazolinderivater som aurorakinaseinhibitorer

Country Status (16)

Country Link
US (1) US20060178382A1 (no)
EP (1) EP1644361A1 (no)
JP (1) JP2006527748A (no)
KR (1) KR20060011891A (no)
CN (1) CN1835945A (no)
AR (1) AR045694A1 (no)
AU (1) AU2004249477A1 (no)
BR (1) BRPI0411503A (no)
CA (1) CA2529250A1 (no)
IL (1) IL172375A0 (no)
MX (1) MXPA05013825A (no)
NO (1) NO20055891L (no)
TW (1) TW200505452A (no)
UY (1) UY28366A1 (no)
WO (1) WO2004113324A1 (no)
ZA (1) ZA200510257B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060003351A (ko) * 2003-04-16 2006-01-10 아스트라제네카 아베 화합물
EP1635837B1 (en) * 2003-06-02 2008-07-16 AstraZeneca AB (3-((quinazolin-4-yl)amino)-1h-pyrazol-1-yl)acetamide derivatives and related compounds as aurora kinase inhibitors for the treatment of proliferative diseases such as cancer
EP1694686A1 (en) 2003-12-19 2006-08-30 Takeda San Diego, Inc. Kinase inhibitors
JP2008510734A (ja) 2004-08-18 2008-04-10 タケダ サン ディエゴ インコーポレイテッド キナーゼ阻害剤
AU2005293336B2 (en) * 2004-10-12 2009-05-28 Astrazeneca Ab Quinazoline derivatives
EP1812439B2 (en) 2004-10-15 2017-12-06 Takeda Pharmaceutical Company Limited Kinase inhibitors
ES2319462T3 (es) * 2005-03-28 2009-05-07 Bristol-Myers Squibb Company Inhibidores competitivos de atp cinasas.
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
JP2009528335A (ja) * 2006-03-02 2009-08-06 アストラゼネカ アクチボラグ キナゾリン誘導体
UY30183A1 (es) 2006-03-02 2007-10-31 Astrazeneca Ab Derivados de quinolina
US20070287706A1 (en) * 2006-05-18 2007-12-13 Dickson John K Jr Certain substituted quinolones, compositions, and uses thereof
GB0619342D0 (en) * 2006-09-30 2006-11-08 Vernalis R&D Ltd New chemical compounds
JP2010505962A (ja) 2006-10-09 2010-02-25 武田薬品工業株式会社 キナーゼ阻害剤
WO2009114703A2 (en) * 2008-03-12 2009-09-17 Fox Chase Cancer Center Combination therapy for the treatment of cancer
EP3615526B1 (en) * 2017-04-27 2021-08-04 Astrazeneca AB Phenoxyquinazoline compounds and their use in treating cancer
WO2018197642A1 (en) * 2017-04-27 2018-11-01 Astrazeneca Ab C5-anilinoquinazoline compounds and their use in treating cancer
KR20190043842A (ko) 2017-10-19 2019-04-29 건국대학교 산학협력단 피리미딘-2-아민 유도체, 이의 제조방법 및 이를 포함하는 항암제
CN110372666B (zh) * 2018-04-13 2022-11-08 华东理工大学 喹唑啉类化合物作为egfr三突变抑制剂及其应用
US20230063230A1 (en) * 2019-02-19 2023-03-02 The Regents Of The University Of California Nurr1 receptor modulators
KR102061458B1 (ko) 2019-08-14 2019-12-31 건국대학교 산학협력단 피리미딘-2-아민 유도체, 이의 제조방법 및 이를 포함하는 항암제
CN112939948B (zh) * 2019-12-11 2022-05-17 苏州美诺医药科技有限公司 新型含喹唑啉类化合物及其中间体与应用
CN113200964B (zh) * 2021-04-25 2022-07-05 南方医科大学南方医院 18f标记的egfr正电子显像剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9922171D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Chemical compounds
IL153246A0 (en) * 2000-06-28 2003-07-06 Astrazeneca Ab Substituted quinazoline derivatives and their use as inhibitors
US7132427B2 (en) * 2001-06-21 2006-11-07 Ariad Pharmaceuticals, Inc. Quinazolines and uses thereof
NZ533440A (en) * 2001-12-24 2006-08-31 Astrazeneca Ab Substituted quinazoline derivatives as inhibitors of aurora kinases

Also Published As

Publication number Publication date
TW200505452A (en) 2005-02-16
MXPA05013825A (es) 2006-02-28
CN1835945A (zh) 2006-09-20
ZA200510257B (en) 2007-05-30
US20060178382A1 (en) 2006-08-10
IL172375A0 (en) 2009-02-11
BRPI0411503A (pt) 2006-07-25
CA2529250A1 (en) 2004-12-29
WO2004113324A1 (en) 2004-12-29
AU2004249477A1 (en) 2004-12-29
EP1644361A1 (en) 2006-04-12
KR20060011891A (ko) 2006-02-03
AR045694A1 (es) 2005-11-09
JP2006527748A (ja) 2006-12-07
UY28366A1 (es) 2005-01-31

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