[go: up one dir, main page]

NO20054904L - Ikke-vandige enkeltfasebaerere og formuleringer uttrykkende slike baerere - Google Patents

Ikke-vandige enkeltfasebaerere og formuleringer uttrykkende slike baerere

Info

Publication number
NO20054904L
NO20054904L NO20054904A NO20054904A NO20054904L NO 20054904 L NO20054904 L NO 20054904L NO 20054904 A NO20054904 A NO 20054904A NO 20054904 A NO20054904 A NO 20054904A NO 20054904 L NO20054904 L NO 20054904L
Authority
NO
Norway
Prior art keywords
carriers
drug formulations
formulations
vehicles
aqueous
Prior art date
Application number
NO20054904A
Other languages
English (en)
Other versions
NO20054904D0 (no
Inventor
Stephen A Berry
Pamela J Fereira
Michael A Desjardin
Catherine Rohloff
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33159638&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20054904(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of NO20054904D0 publication Critical patent/NO20054904D0/no
Publication of NO20054904L publication Critical patent/NO20054904L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Det beskrives materialer og metoder for å tilveiebringe vehikler eller bærere som er brukbare for å tilveiebringe medikamentformuleringer som tar sikte på å bøte på de potensielle mangler ved kjente, ikke-vandige formuleringer. Særlig inkluderer oppfinnelsen ikke-vandige vehikler som er dannet ved bruk av en kombinasjon av polymerer og oppløsningsmidler som resulterer i et vehikkel som er blandbart med vann. De ikke-vandige vehikler letter formuleringen av medikamentformuleringene som er stabile over tid, selv når de lagres ved eller eksponeres til forhøyede temperaturer. Videre tillater de blandbare vehikler ifølge oppfinnelsen fremstilling av medikamentformuleringer som bevirker reduksjon av opptreden av partiell eller fullstendig tilstopning av avleveringsledningene som er inkludert i avleveringsinnretninger som benyttes for å administrere medikamentformuleringene.
NO20054904A 2003-03-31 2005-10-24 Ikke-vandige enkeltfasebaerere og formuleringer uttrykkende slike baerere NO20054904L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45930003P 2003-03-31 2003-03-31
PCT/US2004/009755 WO2004089335A2 (en) 2003-03-31 2004-03-31 Non-aqueous single phase vehicles and formulations utilizing such vehicles

Publications (2)

Publication Number Publication Date
NO20054904D0 NO20054904D0 (no) 2005-10-24
NO20054904L true NO20054904L (no) 2005-12-15

Family

ID=33159638

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054904A NO20054904L (no) 2003-03-31 2005-10-24 Ikke-vandige enkeltfasebaerere og formuleringer uttrykkende slike baerere

Country Status (19)

Country Link
US (3) US20050008661A1 (no)
EP (1) EP1610765B1 (no)
JP (1) JP2006522133A (no)
KR (1) KR20060002922A (no)
CN (1) CN1767815A (no)
AR (1) AR043811A1 (no)
AT (1) ATE404175T1 (no)
AU (2) AU2004227837A1 (no)
BR (1) BRPI0408925A (no)
CA (1) CA2520775A1 (no)
CL (1) CL2004000698A1 (no)
DE (1) DE602004015755D1 (no)
MX (1) MXPA05010602A (no)
NO (1) NO20054904L (no)
NZ (1) NZ542867A (no)
RU (1) RU2005133427A (no)
TW (1) TW200505500A (no)
WO (1) WO2004089335A2 (no)
ZA (1) ZA200508782B (no)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US20050260259A1 (en) * 2004-04-23 2005-11-24 Bolotin Elijah M Compositions for treatment with glucagon-like peptide, and methods of making and using the same
US7635463B2 (en) * 2002-02-27 2009-12-22 Pharmain Corporation Compositions for delivery of therapeutics and other materials
ATE494010T1 (de) * 2002-02-27 2011-01-15 Pharmain Corp Zusammensetzungen zur abgabe von therapeutika und anderen materialien und verfahren zu ihrer herstellung und verwendung
EP1536767B1 (en) * 2002-06-17 2007-08-08 Alza Corporation Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
EP1613389B8 (en) 2003-03-31 2008-05-07 Intarcia Therapeutics, Inc. Osmotic pump with means for dissipating internal pressure
US20050008661A1 (en) * 2003-03-31 2005-01-13 Fereira Pamela J. Non-aqueous single phase vehicles and formulations utilizing such vehicles
CA2520766A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
CA2820537C (en) 2003-04-23 2015-10-20 Valeritas, Inc. Hydraulically actuated pump for fluid administration
PL380763A1 (pl) * 2003-10-31 2007-03-05 Alza Corporation Pompa osmotyczna z samoczynnie mocowanym korkiem membranowym szybkiego uruchamiania
KR20060121890A (ko) * 2003-11-06 2006-11-29 알자 코포레이션 이식형 삼투 펌프와 함께 사용하기 위한 모듈식 흡수율감소기
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US9089636B2 (en) * 2004-07-02 2015-07-28 Valeritas, Inc. Methods and devices for delivering GLP-1 and uses thereof
US7772182B2 (en) * 2004-08-05 2010-08-10 Alza Corporation Stable suspension formulations of erythropoietin receptor agonists
US20060045891A1 (en) * 2004-08-24 2006-03-02 Lovalenti Phillip M Density-matched suspension vehicles and pharmaceutical suspensions
TW200640483A (en) * 2005-02-03 2006-12-01 Alza Corp Non-aqueous single phase vehicles and formulations utilizing such vehicles
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
WO2006083950A2 (en) * 2005-02-03 2006-08-10 Alza Corporation Method for reducing the level of peroxides in bopcompatible polymer preparations
US20060216242A1 (en) * 2005-02-03 2006-09-28 Rohloff Catherine M Suspending vehicles and pharmaceutical suspensions for drug dosage forms
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
EP1877077A2 (en) * 2005-02-03 2008-01-16 Intarcia Therapeutics, Inc. An implantable interferon-containing device
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
JP2009520040A (ja) 2005-12-19 2009-05-21 ファーマイン コーポレーション 治療薬の送達のための疎水性コアの担体組成物、及び同担体組成物の作製法及び使用法
ES2656675T3 (es) 2006-03-30 2018-02-28 Valeritas, Inc. Dispositivo de suministro de fluidos de múltiples cartuchos
MX2008014870A (es) 2006-05-30 2009-02-12 Intarcia Therapeutics Inc Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas.
MX2009001114A (es) 2006-08-09 2009-02-10 Intarcia Therapeutics Inc Sistemas de suministro osmotico y ensambles de piston.
JP5018307B2 (ja) * 2006-09-26 2012-09-05 富士通株式会社 レジストパターン厚肉化材料、レジストパターンの形成方法、半導体装置及びその製造方法
CN104000779A (zh) 2007-04-23 2014-08-27 精达制药公司 促胰岛素释放肽的混悬制剂及其应用
US7960336B2 (en) * 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
US8563527B2 (en) * 2007-08-20 2013-10-22 Pharmain Corporation Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same
KR20100057050A (ko) * 2007-09-11 2010-05-28 몬도바이오테크 래보래토리즈 아게 치료제로서의 데슬로렐린 및 마스토파란의 용도
US20090176892A1 (en) * 2008-01-09 2009-07-09 Pharmain Corporation Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US20100092566A1 (en) * 2008-10-15 2010-04-15 Alessi Thomas R Highly concentrated drug particles, formulations, suspensions and uses thereof
DK2462246T3 (da) 2009-09-28 2017-11-06 Intarcia Therapeutics Inc Hurtig etablering og/eller afslutning af væsentlig steady-state-lægemiddelafgivelse
US9072668B2 (en) 2010-03-09 2015-07-07 Janssen Biotech, Inc. Non-aqueous high concentration reduced viscosity suspension formulations of antibodies
US20110223208A1 (en) 2010-03-09 2011-09-15 Beth Hill Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9956287B2 (en) * 2013-02-06 2018-05-01 Perosphere Inc. Stable glucagon formulations
IL312865B2 (en) 2013-09-11 2025-06-01 Eagle Biologics Inc Liquid protein formulations containing viscosity-lowering agents
EP3131532A1 (de) 2014-04-16 2017-02-22 Veyx-Pharma GmbH Veterinärpharmazeutische zusammensetzung und deren verwendung
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
AU2015325055B2 (en) 2014-10-01 2021-02-25 Eagle Biologics, Inc. Polysaccharide and nucleic acid formulations containing viscosity-lowering agents
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
MA53353A (fr) 2016-05-16 2021-06-09 Intarcia Therapeutics Inc Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
KR20190104039A (ko) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법
EP3624846B1 (en) 2017-05-16 2024-08-07 Bhami's Research Laboratory, Pvt. Ltd. High concentration protein formulations with reduced viscosity including a combination of nicotinic acid and tryoptophan
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
KR20230145053A (ko) 2021-01-12 2023-10-17 듀렉트 코퍼레이션 지속 방출 약물 전달 시스템 및 관련 방법

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069251A (en) * 1969-02-08 1978-01-17 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler Continuous process for the manufacture of methionine
US3797492A (en) * 1972-12-27 1974-03-19 Alza Corp Device for dispensing product with directional guidance member
US3987790A (en) * 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4305927A (en) * 1979-02-05 1981-12-15 Alza Corporation Method for the management of intraocular pressure
US4304767A (en) * 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
US4562024A (en) * 1982-07-06 1985-12-31 Sterling Drug Inc. Process for preparing granulate containing poorly compressible medicinally active matter
US4865845A (en) * 1986-03-21 1989-09-12 Alza Corporation Release rate adjustment of osmotic or diffusional delivery devices
JPS62267326A (ja) * 1986-05-15 1987-11-20 Sanyo Chem Ind Ltd ポリエ−テルの精製法
JPH0657722B2 (ja) * 1986-05-27 1994-08-03 三菱化成株式会社 水溶性ポリマ−組成物
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5059423A (en) * 1988-12-13 1991-10-22 Alza Corporation Delivery system comprising biocompatible beneficial agent formulation
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5110596A (en) * 1988-12-13 1992-05-05 Alza Corporation Delivery system comprising means for delivering agent to livestock
US5057318A (en) * 1988-12-13 1991-10-15 Alza Corporation Delivery system for beneficial agent over a broad range of rates
US5219572A (en) * 1989-03-17 1993-06-15 Pitman-Moore, Inc. Controlled release delivery device for macromolecular proteins
US5112614A (en) * 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
ATE164080T1 (de) * 1990-05-10 1998-04-15 Bechgaard Int Res Pharmazeutische zubereitung enthaltend n- glykofurole und n-äthylenglykole
US5234692A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5234693A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5151093A (en) * 1990-10-29 1992-09-29 Alza Corporation Osmotically driven syringe with programmable agent delivery
GB9027422D0 (en) * 1990-12-18 1991-02-06 Scras Osmotically driven infusion device
US5137727A (en) * 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
US5221698A (en) * 1991-06-27 1993-06-22 The Regents Of The University Of Michigan Bioactive composition
US5288214A (en) * 1991-09-30 1994-02-22 Toshio Fukuda Micropump
DE4137649C2 (de) * 1991-11-15 1997-11-20 Gerhard Dingler Bauelement
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5368588A (en) * 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
US5639477A (en) * 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
DE4403567A1 (de) * 1994-02-07 1995-08-10 Storz Karl Gmbh & Co Vorrichtung zur Durchführung endoskopischer Operationen mittels einer intra- und/oder extrakorporalen Hülle
US5697975A (en) * 1994-02-09 1997-12-16 The University Of Iowa Research Foundation Human cerebral cortex neural prosthetic for tinnitus
NL9401150A (nl) * 1994-07-12 1996-02-01 Nederland Ptt Werkwijze voor het aan een ontvangzijde aanbieden van een van een zendzijde afkomstig eerste aantal videosignalen, alsmede systeem, alsmede zender, alsmede netwerk, en alsmede ontvanger.
EP0788351B1 (en) 1994-11-10 2003-02-05 The University of Kentucky Research Foundation Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body
SE9501189D0 (sv) * 1995-03-31 1995-03-31 Pharmacia Ab Protein formulation
US7833543B2 (en) 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
US6261584B1 (en) * 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
PL189289B1 (pl) * 1996-02-02 2005-07-29 Alza Corp Sposób przygotowania implantowanego układu do dostarczania substancji aktywnej
US6132420A (en) * 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US6156331A (en) * 1996-02-02 2000-12-05 Alza Corporation Sustained delivery of an active agent using an implantable system
US5976109A (en) * 1996-04-30 1999-11-02 Medtronic, Inc. Apparatus for drug infusion implanted within a living body
IL123505A (en) * 1996-07-08 2004-12-15 Penwest Pharmaceuticals Compan Sustained release matrix for high-dose insoluble drugs
US5780431A (en) * 1996-09-20 1998-07-14 Neurobiological Technologies, Inc. Pharmaceutical formulations of corticotropin releasing factor having improved stability in liquid form
AU739469B2 (en) * 1996-12-20 2001-10-11 Alza Corporation Gel composition and methods
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
US5874388A (en) * 1997-04-02 1999-02-23 Dow Corning Corporation Lubricant composition for disc brake caliper pin and a disc brake asembly containing the lubricant
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
JP3703262B2 (ja) * 1997-08-19 2005-10-05 三井化学株式会社 ポリオキシアルキレンポリオール、軟質ポリウレタンフォーム及び非発泡ポリウレタンの製造方法
KR100576583B1 (ko) * 1997-12-22 2006-05-04 알자 코포레이션 서방성 약물 송달 장치용 속도 조절막
WO1999033446A1 (en) 1997-12-29 1999-07-08 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
KR100568917B1 (ko) * 1997-12-30 2006-04-07 알자 코포레이션 멤브레인 플러그를 갖는 익제 전달장치
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
US6248112B1 (en) * 1998-09-30 2001-06-19 C. R. Bard, Inc. Implant delivery system
WO2000033866A1 (en) * 1998-12-04 2000-06-15 Provalis Uk Limited Pharmaceutical compositions containing insulin
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
WO2000045790A2 (en) * 1999-02-08 2000-08-10 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
WO2002043800A2 (en) 2000-11-29 2002-06-06 Durect Corporation Devices and methods for controlled delivery from a drug delivery device
US6541021B1 (en) 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
US20030059376A1 (en) * 1999-06-04 2003-03-27 Libbey Miles A. Formulations comprising dehydrated particles of pharmaceutical agents and process for preparing the same
CN100389821C (zh) * 1999-10-04 2008-05-28 希龙公司 稳定化的含多肽的液体药物组合物
US6436091B1 (en) * 1999-11-16 2002-08-20 Microsolutions, Inc. Methods and implantable devices and systems for long term delivery of a pharmaceutical agent
AU2092701A (en) 1999-12-17 2001-06-25 Durect Corporation Devices and methods in intracerebrospinal delivery of morphine-6-glucuronide
EP1328256B1 (en) * 1999-12-21 2005-10-19 Alza Corporation Valve for osmotic devices
US6283949B1 (en) * 1999-12-27 2001-09-04 Advanced Cardiovascular Systems, Inc. Refillable implantable drug delivery pump
AU2001900A (en) * 1999-12-29 2001-07-16 Progen S.R.L. Biocompatible hydrogel and method of its production
US6572890B2 (en) 2000-01-13 2003-06-03 Osmotica Corp. Osmotic device containing venlafaxine and an anti-psychotic agent
CA2494241C (en) * 2000-02-08 2011-06-14 Allergan, Inc. Botulinum toxin pharmaceutical compositions
US6495534B2 (en) * 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
WO2002028366A2 (en) 2000-10-06 2002-04-11 Durect Corporation Devices and methods for management of inflammation
WO2002067895A2 (en) 2000-11-16 2002-09-06 Durect Corporation Implant dosage form and use thereof for the delivery of a cholesterol lowering agent
IL159048A0 (en) * 2001-06-21 2004-05-12 Genentech Inc Sustained release formulation
WO2003004009A1 (en) * 2001-07-02 2003-01-16 Geneva Pharmaceuticals, Inc. Pharmaceutical composition
NZ533436A (en) * 2001-11-14 2007-10-26 Alza Corp Catheter injectable depot compositons and uses thereof
KR20040058100A (ko) * 2001-11-14 2004-07-03 알자 코포레이션 주입가능한 데포 조성물 및 그의 용도
GB2386066A (en) * 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
AU2003221888B2 (en) * 2002-04-11 2008-11-06 Medimmune, Llc Preservation of bioactive materials by spray drying
US20040001889A1 (en) * 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
IL166418A0 (en) * 2002-07-31 2006-01-15 Alza Corp Injectable depot compositions and uses thereof
BR0315304A (pt) * 2002-11-06 2005-08-16 Alza Corp Formulações com depósito para liberação controlada
RU2342118C2 (ru) * 2002-12-19 2008-12-27 Алза Корпорейшн Стабильные неводные однофазные гели и композиции на их основе для доставки из имплантируемого устройства
US20050008661A1 (en) * 2003-03-31 2005-01-13 Fereira Pamela J. Non-aqueous single phase vehicles and formulations utilizing such vehicles
PL380763A1 (pl) * 2003-10-31 2007-03-05 Alza Corporation Pompa osmotyczna z samoczynnie mocowanym korkiem membranowym szybkiego uruchamiania
US20050118206A1 (en) 2003-11-14 2005-06-02 Luk Andrew S. Surfactant-based gel as an injectable, sustained drug delivery vehicle

Also Published As

Publication number Publication date
EP1610765B1 (en) 2008-08-13
CN1767815A (zh) 2006-05-03
US20130251674A1 (en) 2013-09-26
CL2004000698A1 (es) 2005-05-20
BRPI0408925A (pt) 2006-04-04
AU2004227837A1 (en) 2004-10-21
NO20054904D0 (no) 2005-10-24
HK1090834A1 (en) 2007-01-05
DE602004015755D1 (de) 2008-09-25
AR043811A1 (es) 2005-08-17
ATE404175T1 (de) 2008-08-15
KR20060002922A (ko) 2006-01-09
ZA200508782B (en) 2007-02-28
US20050008661A1 (en) 2005-01-13
AU2010212478B2 (en) 2011-06-23
NZ542867A (en) 2009-02-28
JP2006522133A (ja) 2006-09-28
AU2010212478A1 (en) 2010-09-09
TW200505500A (en) 2005-02-16
WO2004089335A3 (en) 2005-02-10
US20050276856A1 (en) 2005-12-15
US8496943B2 (en) 2013-07-30
MXPA05010602A (es) 2005-11-23
WO2004089335A2 (en) 2004-10-21
CA2520775A1 (en) 2004-10-21
RU2005133427A (ru) 2006-04-27
EP1610765A2 (en) 2006-01-04

Similar Documents

Publication Publication Date Title
NO20054904L (no) Ikke-vandige enkeltfasebaerere og formuleringer uttrykkende slike baerere
WO2005011592A3 (en) Substituted indazole-o-glucosides
WO2005012243A3 (en) Substituted indole-o-glucosides
ATE480223T1 (de) Kosmetische zusammensetzungen mit blockcopolymeren und entsprechendes system von dauerhaften kosmetikprodukten
DK1819353T3 (da) Sammensætning til proteasomhæmning
ATE506939T1 (de) Kosmetische zusammensetzungen mit blockcopolymeren und entsprechendes system von dauerhaften kosmetikprodukten
NO20073065L (no) Injiserbare nanopartikulaere olanzapinformuleringer
UA86042C2 (en) Substituted indazole-o-glucosides
TW200605870A (en) Topical methadone compositions and methods for using the same
WO2004093795A3 (en) Compositions for delivery of drug combinations
WO2003018004A3 (en) Analgetic pyrroline derivatives
WO2007111864A3 (en) Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
MY125921A (en) Compositions containing organic compounds
WO2007136577A3 (en) Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
WO2004112695A3 (en) Methods and compositions for delivery of catecholic butanes for treatment of obesity
WO2003053354A3 (en) Fused cyclic modulators of nuclear hormone receptor function
WO2005084296A3 (en) Fused tricyclic compounds as inhibitors of 17beta-hydroxysteroid dehydrogernase 3
WO2004093800A3 (en) Thyronamine derivatives and analogs and methods of use thereof
AU2003256203A1 (en) Alpha-7 nicotinic receptor agonists and statins in combination
AU2003286474A1 (en) Compositions, solutions, and methods used for transplantation
WO2006002102A3 (en) Spirocyclic compounds useful as modulators of nuclear hormone receptor function
NO20075140L (no) Fremgangsmater og preparater for modulering av vaskulaer integritet
WO2006042173A3 (en) Modulators of hepatocyte growth factor activator
WO2005041936A3 (en) Methods of treatment of cancer using a composition comprising a cytotoxic drug and a porous carrier material
WO2006041538A3 (en) A mixture for transdermal delivery of low and high molecular weight compounds

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application