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NO20054669L - Substituerte kinobenzoxazinanaloger - Google Patents

Substituerte kinobenzoxazinanaloger

Info

Publication number
NO20054669L
NO20054669L NO20054669A NO20054669A NO20054669L NO 20054669 L NO20054669 L NO 20054669L NO 20054669 A NO20054669 A NO 20054669A NO 20054669 A NO20054669 A NO 20054669A NO 20054669 L NO20054669 L NO 20054669L
Authority
NO
Norway
Prior art keywords
analogues
quinobenzoxazine
substituted
substituted quinobenzoxazine
present
Prior art date
Application number
NO20054669A
Other languages
English (en)
Other versions
NO20054669D0 (no
Inventor
Jeffrey P Whitten
Michael K Schwaebe
Adam Siddiqui-Jain
Terrance Moran
Original Assignee
Cylene Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cylene Pharmaceuticals Inc filed Critical Cylene Pharmaceuticals Inc
Publication of NO20054669D0 publication Critical patent/NO20054669D0/no
Publication of NO20054669L publication Critical patent/NO20054669L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Den foreliggende oppfinnelsen dreier seg om kinobenzoksazinanaloger av generell formel: og farmasøytisk aksepterbare salter, estere og promedikamenter av disse; hvor A, U, V, W, X og Z er substituenter. Den foreliggende opfinnelsen dreier seg også om fremgangsmåter for bruk av slike forbindelser.
NO20054669A 2003-04-07 2005-10-11 Substituerte kinobenzoxazinanaloger NO20054669L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US46127103P 2003-04-07 2003-04-07
US46317103P 2003-04-15 2003-04-15
US51953503P 2003-11-12 2003-11-12
US53272703P 2003-12-23 2003-12-23
PCT/US2004/011108 WO2004091504A2 (en) 2003-04-07 2004-04-07 Substituted quinobenzoxazine analogs

Publications (2)

Publication Number Publication Date
NO20054669D0 NO20054669D0 (no) 2005-10-11
NO20054669L true NO20054669L (no) 2005-11-14

Family

ID=33304104

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054669A NO20054669L (no) 2003-04-07 2005-10-11 Substituerte kinobenzoxazinanaloger

Country Status (11)

Country Link
US (5) US7141565B1 (no)
EP (1) EP1610759A4 (no)
JP (1) JP2006522827A (no)
KR (1) KR100944600B1 (no)
AU (1) AU2004229489B2 (no)
BR (1) BRPI0409105A (no)
CA (1) CA2521810A1 (no)
MX (1) MXPA05010776A (no)
NO (1) NO20054669L (no)
NZ (1) NZ543006A (no)
WO (1) WO2004091504A2 (no)

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US7507727B2 (en) * 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
KR100944600B1 (ko) 2003-04-07 2010-02-25 사일린 파마슈티칼스, 인크 치환된 퀴노벤족사진 유사체
US7354916B2 (en) 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
WO2005037997A2 (en) * 2003-10-14 2005-04-28 Cylene Pharmaceuticals, Inc. Competition assay for identifying modulators of quadruplex nucleic acids
DE102004035203A1 (de) * 2004-07-21 2006-02-16 Bayer Healthcare Ag Substituierte Chinolone
NZ553746A (en) * 2004-09-17 2010-06-25 Cylene Pharmaceuticals Inc Quinolone analogs as cell proliferation inhibitors
US7652134B2 (en) * 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
EP1874731A4 (en) * 2005-04-15 2009-08-05 Cylene Pharmaceuticals Inc CHINOBENZOXAZINANALOGA AND METHOD FOR THE APPLICATION
US7610985B2 (en) * 2005-05-18 2009-11-03 Kanzaki Kokyukoki Mfg. Co., Ltd. HST unit
DE102006005861A1 (de) 2006-02-09 2007-08-23 Aicuris Gmbh & Co. Kg Substituierte Chinolone III
US8481529B2 (en) * 2006-05-16 2013-07-09 The Arizona Board Of Regents On Behalf Of The University Of Arizona Combination cancer chemotherapy
CA2654151A1 (en) * 2006-06-03 2007-12-13 Cylene Pharmaceuticals, Inc. Drug administration methods
US8410070B2 (en) * 2008-09-12 2013-04-02 University Of Louisville Research Foundation, Inc. Compositions and methods for treating cancer, inhibiting proliferation, and inducing cell death
US8470817B2 (en) 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
US9730609B2 (en) * 2011-12-15 2017-08-15 Siemens Healthcare Gmbh Method and system for aortic valve calcification evaluation
JP6249436B2 (ja) * 2012-08-31 2017-12-20 国立大学法人東京農工大学 四重らせんｄｎａ検出プローブ及びそれを用いた四重らせん構造の検出方法
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
SG11201609171XA (en) 2014-05-09 2016-12-29 Pimera Inc Novel compositions, uses and methods for making them
JP2020512975A (ja) 2017-03-28 2020-04-30 ピメラ，インク． Ｐｏｌ１阻害剤の新規な結晶形態
US11071727B2 (en) 2018-01-26 2021-07-27 Northwestern University Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
CN114716373B (zh) * 2022-04-14 2023-01-10 内蒙古源宏精细化工有限公司 一种加替沙星环合酯的制备方法
CN116023263A (zh) * 2022-11-17 2023-04-28 苏州汉德创宏生化科技有限公司 一种中间体3-(3,5-二氯苯基)-3-氧代丙酸乙酯的合成方法

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Also Published As

Publication number Publication date
WO2004091504A2 (en) 2004-10-28
WO2004091504A3 (en) 2006-01-05
US7612063B2 (en) 2009-11-03
US7326702B2 (en) 2008-02-05
JP2006522827A (ja) 2006-10-05
EP1610759A4 (en) 2007-04-25
AU2004229489B2 (en) 2010-03-04
EP1610759A2 (en) 2006-01-04
US20120122804A1 (en) 2012-05-17
US7381720B2 (en) 2008-06-03
NZ543006A (en) 2009-03-31
AU2004229489A1 (en) 2004-10-28
KR100944600B1 (ko) 2010-02-25
CA2521810A1 (en) 2004-10-28
US20070043039A1 (en) 2007-02-22
US20060229303A1 (en) 2006-10-12
US20080261963A1 (en) 2008-10-23
KR20060029210A (ko) 2006-04-05
BRPI0409105A (pt) 2006-04-25
US7141565B1 (en) 2006-11-28
MXPA05010776A (es) 2006-05-25
NO20054669D0 (no) 2005-10-11

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