NO20053090L - Powder formulation for inhalation containing tiotropium. - Google Patents
Powder formulation for inhalation containing tiotropium.Info
- Publication number
- NO20053090L NO20053090L NO20053090A NO20053090A NO20053090L NO 20053090 L NO20053090 L NO 20053090L NO 20053090 A NO20053090 A NO 20053090A NO 20053090 A NO20053090 A NO 20053090A NO 20053090 L NO20053090 L NO 20053090L
- Authority
- NO
- Norway
- Prior art keywords
- powder formulation
- containing tiotropium
- inhalation containing
- inhalation
- treatment
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000843 powder Substances 0.000 title 1
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title 1
- 229940110309 tiotropium Drugs 0.000 title 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Det beskrives tiotiopium-holdige pulverformede tilberedninger for inhalasjon, fremgangsmåter for fremstiUing av disse, samt deres anvendelse til fremstiUing av et legemiddel til behandling av luftveissykdommer, særhg til behandling av eOPD (chronic obstructive pulmonary disease = kronisk obstruktiv lungesykdom) og astma.Thiotiopium-containing powdered preparations are described for inhalation, methods of preparing them, and their use in the manufacture of a medicament for the treatment of respiratory diseases, particularly for the treatment of chronic obstructive pulmonary disease (EOPD) and asthma.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10255387A DE10255387A1 (en) | 2002-11-28 | 2002-11-28 | New tiotropium-containing powder formulation for inhalation |
| PCT/EP2003/012911 WO2004047796A2 (en) | 2002-11-28 | 2003-11-19 | Pulverulent formulation for inhalation containing tiotropium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20053090L true NO20053090L (en) | 2005-06-23 |
| NO20053090D0 NO20053090D0 (en) | 2005-06-23 |
Family
ID=32308760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053090A NO20053090D0 (en) | 2002-11-28 | 2005-06-23 | Powder formulation for inhalation containing tiotropium. |
Country Status (33)
| Country | Link |
|---|---|
| EP (1) | EP1567135B1 (en) |
| JP (1) | JP4977321B2 (en) |
| KR (1) | KR101066805B1 (en) |
| CN (1) | CN100574751C (en) |
| AR (1) | AR042242A1 (en) |
| AT (1) | ATE401861T1 (en) |
| AU (1) | AU2003294714B2 (en) |
| BR (1) | BR0316343A (en) |
| CA (1) | CA2507579C (en) |
| CO (1) | CO5580736A2 (en) |
| CY (1) | CY1108420T1 (en) |
| DE (2) | DE10255387A1 (en) |
| DK (1) | DK1567135T3 (en) |
| EA (1) | EA011549B1 (en) |
| EC (1) | ECSP055821A (en) |
| ES (1) | ES2310681T3 (en) |
| HR (1) | HRP20050468A2 (en) |
| IL (1) | IL168810A (en) |
| ME (1) | MEP51608A (en) |
| MX (1) | MXPA05005485A (en) |
| MY (1) | MY140890A (en) |
| NO (1) | NO20053090D0 (en) |
| PE (1) | PE20040848A1 (en) |
| PL (1) | PL376229A1 (en) |
| PT (1) | PT1567135E (en) |
| RS (1) | RS20050400A (en) |
| SA (1) | SA04240467B1 (en) |
| SI (1) | SI1567135T1 (en) |
| TW (1) | TWI332837B (en) |
| UA (1) | UA81930C2 (en) |
| UY (1) | UY28096A1 (en) |
| WO (1) | WO2004047796A2 (en) |
| ZA (1) | ZA200502859B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006016904A1 (en) | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | inhaler |
| DE102008014025A1 (en) * | 2008-03-13 | 2009-09-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhaler and strainer for an inhaler |
| TR200909788A2 (en) | 2009-12-25 | 2011-07-21 | Bi̇lgi̇ç Mahmut | Dry powder formulation suitable for inhalation with tiotropium |
| GEP20156343B (en) * | 2010-08-03 | 2015-08-10 | Chiesi Farma Spa | Dry powder formulation comprising a phosphodiesterase inhibitor |
| WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
| KR101748796B1 (en) * | 2015-09-30 | 2017-06-19 | 한미약품 주식회사 | Inhalation capsule with enhanced delivery rate of active ingredients |
| KR101728116B1 (en) * | 2015-11-03 | 2017-04-18 | 한미약품 주식회사 | Dry powder composition for inhalation comprising tiotropium or pharmaceutically acceptable salt thereof |
| CN111514418B (en) * | 2019-06-12 | 2022-01-14 | 中南大学湘雅二医院 | Self-suction nasal powder material feeding device |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957965A (en) * | 1967-08-08 | 1976-05-18 | Fisons Limited | Sodium chromoglycate inhalation medicament |
| GB1242211A (en) * | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
| DE4140689B4 (en) * | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalable powders and process for their preparation |
| DE4318455A1 (en) * | 1993-06-03 | 1994-12-08 | Boehringer Ingelheim Kg | Capsule holder |
| GB9322014D0 (en) * | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
| DE4425255A1 (en) * | 1994-07-16 | 1996-01-18 | Asta Medica Ag | Formulation for inhalation application |
| DK1131059T3 (en) * | 1998-11-13 | 2003-06-30 | Jago Res Ag | Dry powder for inhalation |
| GB9902689D0 (en) * | 1999-02-08 | 1999-03-31 | Novartis Ag | Organic compounds |
| BR0107304A (en) * | 2000-10-12 | 2002-08-13 | Boehringer Ingelheim Pharma | Inhalation powder containing tiotropium |
| UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| DE10126924A1 (en) * | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalation capsule contains powdered mixture of tiotropium and auxiliary, for treating asthma or chronic obstructive pulmonary disease, having capsule material of low moisture content to improve stability |
| DE10141377A1 (en) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Scattering process for the production of powder formulations |
| BR0308984A (en) * | 2002-04-04 | 2005-02-09 | Boehringer Ingelheim Pharma | Powder formulations suitable for inhalation |
| UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
-
2002
- 2002-11-28 DE DE10255387A patent/DE10255387A1/en not_active Withdrawn
-
2003
- 2003-11-19 EA EA200500864A patent/EA011549B1/en not_active IP Right Cessation
- 2003-11-19 RS YUP-2005/0400A patent/RS20050400A/en unknown
- 2003-11-19 AT AT03785648T patent/ATE401861T1/en active
- 2003-11-19 CA CA2507579A patent/CA2507579C/en not_active Expired - Fee Related
- 2003-11-19 CN CN200380104599A patent/CN100574751C/en not_active Expired - Lifetime
- 2003-11-19 MX MXPA05005485A patent/MXPA05005485A/en active IP Right Grant
- 2003-11-19 ES ES03785648T patent/ES2310681T3/en not_active Expired - Lifetime
- 2003-11-19 DE DE50310208T patent/DE50310208D1/en not_active Expired - Lifetime
- 2003-11-19 UA UAA200506224A patent/UA81930C2/en unknown
- 2003-11-19 SI SI200331323T patent/SI1567135T1/en unknown
- 2003-11-19 PL PL03376229A patent/PL376229A1/en unknown
- 2003-11-19 EP EP03785648A patent/EP1567135B1/en not_active Revoked
- 2003-11-19 AU AU2003294714A patent/AU2003294714B2/en not_active Expired
- 2003-11-19 PT PT03785648T patent/PT1567135E/en unknown
- 2003-11-19 JP JP2004554384A patent/JP4977321B2/en not_active Expired - Lifetime
- 2003-11-19 HR HR20050468A patent/HRP20050468A2/en not_active Application Discontinuation
- 2003-11-19 KR KR1020057009548A patent/KR101066805B1/en not_active Expired - Lifetime
- 2003-11-19 WO PCT/EP2003/012911 patent/WO2004047796A2/en not_active Ceased
- 2003-11-19 DK DK03785648T patent/DK1567135T3/en active
- 2003-11-19 ME MEP-516/08A patent/MEP51608A/en unknown
- 2003-11-19 BR BR0316343-1A patent/BR0316343A/en not_active Application Discontinuation
- 2003-11-26 PE PE2003001200A patent/PE20040848A1/en not_active Application Discontinuation
- 2003-11-26 UY UY28096A patent/UY28096A1/en not_active Application Discontinuation
- 2003-11-26 TW TW092133185A patent/TWI332837B/en not_active IP Right Cessation
- 2003-11-27 MY MYPI20034544A patent/MY140890A/en unknown
- 2003-11-28 AR ARP030104393A patent/AR042242A1/en unknown
-
2004
- 2004-01-03 SA SA04240467A patent/SA04240467B1/en unknown
-
2005
- 2005-04-08 ZA ZA200502859A patent/ZA200502859B/en unknown
- 2005-05-26 IL IL168810A patent/IL168810A/en not_active IP Right Cessation
- 2005-05-26 EC EC2005005821A patent/ECSP055821A/en unknown
- 2005-06-23 NO NO20053090A patent/NO20053090D0/en not_active Application Discontinuation
- 2005-06-27 CO CO05062904A patent/CO5580736A2/en not_active Application Discontinuation
-
2008
- 2008-10-16 CY CY20081101149T patent/CY1108420T1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |