NO20053089L - Carbamic acid esters with anticolinergic action. - Google Patents
Carbamic acid esters with anticolinergic action.Info
- Publication number
- NO20053089L NO20053089L NO20053089A NO20053089A NO20053089L NO 20053089 L NO20053089 L NO 20053089L NO 20053089 A NO20053089 A NO 20053089A NO 20053089 A NO20053089 A NO 20053089A NO 20053089 L NO20053089 L NO 20053089L
- Authority
- NO
- Norway
- Prior art keywords
- carbamic acid
- acid esters
- action
- anticolinergic
- relates
- Prior art date
Links
- 229940112021 centrally acting muscle relaxants carbamic acid ester Drugs 0.000 title abstract 2
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention relates to novel carbamic acid esters of general formula (1), in which X<-> and the groups A, R<1>, R<2>, R<3> and R<4> can be defined as cited in the claims and the description. The invention also relates to a method for producing said esters and to their use as medicaments, in particular medicaments with an anticholinergic action.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10255040A DE10255040A1 (en) | 2002-11-26 | 2002-11-26 | New carbamic acid esters with anticholinergic activity |
| PCT/EP2003/012912 WO2004048373A1 (en) | 2002-11-26 | 2003-11-19 | Carbamic acid esters with an anticholinergic action |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20053089D0 NO20053089D0 (en) | 2005-06-23 |
| NO20053089L true NO20053089L (en) | 2005-06-23 |
Family
ID=32240420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053089A NO20053089L (en) | 2002-11-26 | 2005-06-23 | Carbamic acid esters with anticolinergic action. |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1567526B1 (en) |
| JP (1) | JP4754829B2 (en) |
| KR (1) | KR20050086821A (en) |
| CN (1) | CN1717408A (en) |
| AT (1) | ATE392424T1 (en) |
| AU (1) | AU2003289880A1 (en) |
| BR (1) | BR0316549A (en) |
| CA (1) | CA2507110C (en) |
| DE (2) | DE10255040A1 (en) |
| EA (1) | EA200500775A1 (en) |
| EC (1) | ECSP055803A (en) |
| ES (1) | ES2304538T3 (en) |
| HR (1) | HRP20050465A2 (en) |
| MX (1) | MXPA05005443A (en) |
| NO (1) | NO20053089L (en) |
| PL (1) | PL376638A1 (en) |
| RS (1) | RS20050384A (en) |
| UA (1) | UA81649C2 (en) |
| WO (1) | WO2004048373A1 (en) |
| ZA (1) | ZA200502946B (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE435862T1 (en) | 2003-05-28 | 2009-07-15 | Theravance Inc | AZABICYCLOALKAN COMPOUNDS AS MUSCARINE RECEPTOR ANTAGONISTS |
| TW200534855A (en) * | 2004-01-13 | 2005-11-01 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
| JP2008505118A (en) * | 2004-06-30 | 2008-02-21 | グラクソ グループ リミテッド | Muscarinic acetylcholine receptor antagonist |
| JP2008520573A (en) * | 2004-11-15 | 2008-06-19 | グラクソ グループ リミテッド | Novel M3 muscarinic acetylcholine receptor antagonist |
| WO2007007282A2 (en) * | 2005-07-11 | 2007-01-18 | Ranbaxy Laboratories Limited | Azabicyclo derivatives as muscarinic receptor antagonists |
| US20090182033A1 (en) * | 2005-12-16 | 2009-07-16 | Argenta Discovery Ltd. | Cyclic Amine Derivatives and Their Uses |
| US8367696B2 (en) | 2007-02-09 | 2013-02-05 | Astellas Pharma Inc. | Aza-bridged-ring compound |
| PT3691620T (en) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| WO2019096226A1 (en) | 2017-11-16 | 2019-05-23 | Chengdu Easton Biopharmaceuticals Co., Ltd. | Pasylated vegfr/pdgfr fusion proteins and their use in therapy |
| JP2021505569A (en) * | 2017-12-04 | 2021-02-18 | フリードリヒ−アレクサンダー−ウニヴェルシテート エアランゲン−ニュルンベルク | Fluorophenyl-substituted muscarinic receptor ligand that is more selective for M3 than M2 |
| KR20220001259A (en) | 2020-06-29 | 2022-01-05 | (주)아모레퍼시픽 | Surface-treated inorganic particles, manufacturing method of the same, dispersion solution of the same and cosmetic composition comprising the same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759460A (en) * | 1969-11-26 | 1971-05-26 | Knoll Ag | NEW CARBAMATES AND THEIR PREPARATION PROCESS |
| GB8600978D0 (en) * | 1986-01-16 | 1986-02-19 | Beecham Group Plc | Compounds |
| IT1228293B (en) * | 1989-02-06 | 1991-06-07 | Angeli Inst Spa | BENZODERIVATES OF HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN. |
| DE4108393A1 (en) * | 1991-03-15 | 1992-09-17 | Boehringer Ingelheim Kg | NEW ESTERS BI-AND TRICYCLIC AMINO ALCOHOLS, THEIR PREPARATION AND THEIR USE IN MEDICINAL PRODUCTS |
| AU7545894A (en) * | 1993-09-02 | 1995-03-22 | Yamanouchi Pharmaceutical Co., Ltd. | Carbamate derivative and medicine containing the same |
| EP0747355A4 (en) * | 1994-02-10 | 1997-04-09 | Yamanouchi Pharma Co Ltd | Novel carbamate derivative and medicinal composition containing the same |
| AU724780B2 (en) * | 1996-03-20 | 2000-09-28 | Wake Forest University | Sigma-2 receptors as biomarkers of tumor cell proliferation |
-
2002
- 2002-11-26 DE DE10255040A patent/DE10255040A1/en not_active Withdrawn
-
2003
- 2003-11-19 AT AT03782212T patent/ATE392424T1/en active
- 2003-11-19 MX MXPA05005443A patent/MXPA05005443A/en active IP Right Grant
- 2003-11-19 KR KR1020057009429A patent/KR20050086821A/en not_active Withdrawn
- 2003-11-19 EP EP03782212A patent/EP1567526B1/en not_active Expired - Lifetime
- 2003-11-19 RS YUP-2005/0384A patent/RS20050384A/en unknown
- 2003-11-19 AU AU2003289880A patent/AU2003289880A1/en not_active Abandoned
- 2003-11-19 BR BR0316549-3A patent/BR0316549A/en not_active IP Right Cessation
- 2003-11-19 UA UAA200506234A patent/UA81649C2/en unknown
- 2003-11-19 ES ES03782212T patent/ES2304538T3/en not_active Expired - Lifetime
- 2003-11-19 CA CA2507110A patent/CA2507110C/en not_active Expired - Fee Related
- 2003-11-19 PL PL376638A patent/PL376638A1/en not_active Application Discontinuation
- 2003-11-19 CN CNA2003801042073A patent/CN1717408A/en active Pending
- 2003-11-19 HR HR20050465A patent/HRP20050465A2/en not_active Application Discontinuation
- 2003-11-19 JP JP2004554385A patent/JP4754829B2/en not_active Expired - Lifetime
- 2003-11-19 WO PCT/EP2003/012912 patent/WO2004048373A1/en not_active Ceased
- 2003-11-19 DE DE50309655T patent/DE50309655D1/en not_active Expired - Lifetime
- 2003-11-19 EA EA200500775A patent/EA200500775A1/en unknown
-
2005
- 2005-04-12 ZA ZA200502946A patent/ZA200502946B/en unknown
- 2005-05-19 EC EC2005005803A patent/ECSP055803A/en unknown
- 2005-06-23 NO NO20053089A patent/NO20053089L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006514010A (en) | 2006-04-27 |
| CA2507110C (en) | 2012-07-10 |
| DE50309655D1 (en) | 2008-05-29 |
| BR0316549A (en) | 2005-10-04 |
| JP4754829B2 (en) | 2011-08-24 |
| PL376638A1 (en) | 2006-01-09 |
| DE10255040A1 (en) | 2004-06-03 |
| ES2304538T3 (en) | 2008-10-16 |
| ECSP055803A (en) | 2005-08-11 |
| NO20053089D0 (en) | 2005-06-23 |
| CN1717408A (en) | 2006-01-04 |
| HRP20050465A2 (en) | 2006-10-31 |
| KR20050086821A (en) | 2005-08-30 |
| AU2003289880A1 (en) | 2004-06-18 |
| EA200500775A1 (en) | 2005-12-29 |
| RS20050384A (en) | 2007-12-31 |
| CA2507110A1 (en) | 2004-06-10 |
| WO2004048373A1 (en) | 2004-06-10 |
| EP1567526B1 (en) | 2008-04-16 |
| UA81649C2 (en) | 2008-01-25 |
| EP1567526A1 (en) | 2005-08-31 |
| MXPA05005443A (en) | 2005-08-03 |
| ZA200502946B (en) | 2005-11-23 |
| ATE392424T1 (en) | 2008-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |