[go: up one dir, main page]

NO20052909D0 - Tetracyclic 3-substituted indoles having serotonin receptor affinity. - Google Patents

Tetracyclic 3-substituted indoles having serotonin receptor affinity.

Info

Publication number
NO20052909D0
NO20052909D0 NO20052909A NO20052909A NO20052909D0 NO 20052909 D0 NO20052909 D0 NO 20052909D0 NO 20052909 A NO20052909 A NO 20052909A NO 20052909 A NO20052909 A NO 20052909A NO 20052909 D0 NO20052909 D0 NO 20052909D0
Authority
NO
Norway
Prior art keywords
tetracyclic
serotonin receptor
receptor affinity
substituted indoles
indoles
Prior art date
Application number
NO20052909A
Other languages
English (en)
Other versions
NO20052909L (no
NO334030B1 (no
Inventor
Venkata Satya Niro Ramakrishna
Vikas Shreekrishna Shirsath
Rama Sastri Kambhampati
Venkata Satya Veerabhadra Rao
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Publication of NO20052909D0 publication Critical patent/NO20052909D0/no
Publication of NO20052909L publication Critical patent/NO20052909L/no
Publication of NO334030B1 publication Critical patent/NO334030B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Addiction (AREA)
NO20052909A 2002-12-18 2005-06-15 Tetrasykliske, 3-substituerte indoler samt deres fremstilling og anvendelse NO334030B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN951MA2002 2002-12-18
PCT/IN2003/000393 WO2004055026A1 (en) 2002-12-18 2003-12-16 Tetracyclic 3-substituted indoles having serotonin receptor affinity

Publications (3)

Publication Number Publication Date
NO20052909D0 true NO20052909D0 (no) 2005-06-15
NO20052909L NO20052909L (no) 2005-09-12
NO334030B1 NO334030B1 (no) 2013-11-18

Family

ID=40848934

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052909A NO334030B1 (no) 2002-12-18 2005-06-15 Tetrasykliske, 3-substituerte indoler samt deres fremstilling og anvendelse

Country Status (19)

Country Link
US (1) US7781476B2 (no)
EP (1) EP1581538B1 (no)
JP (1) JP4571507B2 (no)
KR (1) KR100739987B1 (no)
CN (1) CN100378109C (no)
AT (1) ATE355292T1 (no)
AU (1) AU2003292510B2 (no)
BR (1) BRPI0316895C1 (no)
CA (1) CA2507923C (no)
DE (1) DE60312226T2 (no)
DK (1) DK1581538T3 (no)
EA (1) EA009367B1 (no)
MX (1) MXPA05005808A (no)
NO (1) NO334030B1 (no)
NZ (1) NZ540841A (no)
PT (1) PT1581538E (no)
SI (1) SI1581538T1 (no)
WO (1) WO2004055026A1 (no)
ZA (1) ZA200504042B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005005439A1 (en) * 2003-07-09 2005-01-20 Suven Life Sciences Limited Benzothiazino indoles
PT1704154E (pt) 2004-01-02 2009-08-05 Suven Life Sciences Ltd Novos indeno[2,1a]indenos e isoindol[2,1-a]indóis
AU2005328870B2 (en) 2005-03-08 2011-02-03 Suven Life Sciences Limited Process for preparing substituted benzothiazinoindoles
EP1919896B1 (en) 2005-08-12 2009-12-23 Suven Life Sciences Limited Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands.
WO2007020654A1 (en) 2005-08-16 2007-02-22 Suven Life Sciences An improved process for the preparation of losartan
EA017007B1 (ru) 2007-01-08 2012-09-28 Сувен Лайф Сайенсиз Лимитед Соединения 5-(гетероциклил)алкил-n-(арилсульфонил)индола и их применение в качестве лигандов 5-ht
US8003670B2 (en) 2007-05-03 2011-08-23 Suven Life Sciences Limited Aminoalkoxy aryl sulfonamide compounds and their use as 5-HT6 ligands
WO2008144263A1 (en) * 2007-05-18 2008-11-27 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
EA017154B1 (ru) * 2007-10-26 2012-10-30 Сувен Лайф Сайенсиз Лимитед Аминоарилсульфонамидные соединения и их применение в качестве 5-нтлигандов
US8318725B2 (en) 2008-09-17 2012-11-27 Suven Life Sciences Limited Aryl indolyl sulfonamide compounds and their use as 5-HT6 ligands
WO2010032258A1 (en) 2008-09-17 2010-03-25 Suven Life Sciences Limited Aryl sulfonamide amine compounds and their use as 5-ht6 ligands
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
IN2013CH05537A (no) * 2013-12-02 2015-06-12 Suven Life Sciences Ltd
KR101938408B1 (ko) * 2014-08-16 2019-01-14 수벤 라이프 사이언시스 리미티드 1-[(2-브로모페닐) 술포닐]-5-메톡시-3-[(4-메틸-1-피페라지닐) 메틸]-1h-인돌 디메실레이트 모노히드레이트의 활성 대사산물 및 상기 활성 대사산물의 디메실레이트 디히드레이트 염
HK1258023A1 (zh) * 2016-05-18 2019-11-01 Suven Life Sciences Limited 纯5-ht6受体拮抗剂与nmda受体拮抗剂的组合
MX381768B (es) * 2016-05-18 2025-03-13 Suven Life Sciences Ltd Combinación de antagonistas puros del receptor 5-ht6 con inhibidores de la acetilcolinesterasa.
EA036235B1 (ru) * 2016-10-03 2020-10-16 Сувен Лайф Сайенсиз Лимитед Фармацевтические композиции антагониста 5-ht6
WO2019008484A1 (en) * 2017-07-03 2019-01-10 Suven Life Sciences Limited NEW USES OF A PURE 5-HT6 RECEPTOR ANTAGONIST

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489770A (en) * 1967-12-18 1970-01-13 American Home Prod 1-cyclo(lower)alkanoyl or admantanylcarbonyl - 3 - (2-substituted ethyl)indoles
ZA815541B (en) * 1980-08-12 1983-03-30 Glaxo Group Ltd Heterocyclic compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
IL96891A0 (en) 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
AU646871B2 (en) 1990-06-07 1994-03-10 Astrazeneca Uk Limited Therapeutic heterocyclic compounds
CZ283018B6 (cs) 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
GB9113802D0 (en) 1991-06-26 1991-08-14 Smithkline Beecham Plc Medicaments
GB9210400D0 (en) 1992-05-15 1992-07-01 Merck Sharp & Dohme Therapeutic agents
KR940007001A (ko) * 1992-09-16 1994-04-26 최승주 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제
FR2737220B1 (fr) 1995-07-24 1997-09-26 Adir Sequences nucleiques codant pour des recepteurs de la melatonine et leurs applications
JP2000026471A (ja) * 1998-07-10 2000-01-25 Nippon Soda Co Ltd 11−ホルミル−インドロ[1,2−b][1,2]ベンズイソチアゾールおよび農園芸用殺菌剤
GB9820113D0 (en) * 1998-09-15 1998-11-11 Merck Sharp & Dohme Therapeutic agents
DK1149078T3 (da) * 1998-12-11 2006-07-10 Univ Virginia Commonwealth Selektive 5-HT6-receptorligander
US6403808B1 (en) * 1999-12-10 2002-06-11 Virginia Commonwealth University Selective 5-HT6 receptor ligands
IL130169A (en) 1999-05-27 2006-08-20 Neurim Pharma 1991 Indole derivatives, and pharmaceutical preparations, skin protection preparations, and cosmetics containing them
FR2799757B1 (fr) * 1999-10-15 2001-12-14 Adir Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1317276C (zh) * 2000-09-29 2007-05-23 中国科学院上海药物研究所 一类吲哚基哌啶类化合物及其制备方法和用途
CA2429605A1 (en) 2000-11-20 2002-05-30 Scios Inc. Indol derivative and their use as inhibitors of p38 kinase
FR2821843B1 (fr) * 2001-03-12 2003-05-09 Servier Lab Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2005522432A (ja) 2002-02-05 2005-07-28 グラクソ グループ リミテッド ニューロン成長の促進方法
BR0312176A (pt) * 2002-06-21 2005-04-05 Suven Life Sciences Ltd Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediario
ATE444965T1 (de) * 2002-06-21 2009-10-15 Suven Life Sciences Ltd Sich als therapeutische mittel eignende arylalkylindole mit affinität für den serotoninrezeptor, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese enthalten
CN1720227A (zh) * 2002-11-28 2006-01-11 苏文生命科学有限公司 N-芳基磺酰基-3-氨基烷氧基吲哚

Also Published As

Publication number Publication date
JP2006515843A (ja) 2006-06-08
BRPI0316895C1 (pt) 2021-05-25
EA200500994A1 (ru) 2006-02-24
US7781476B2 (en) 2010-08-24
EP1581538A1 (en) 2005-10-05
ATE355292T1 (de) 2006-03-15
KR100739987B1 (ko) 2007-07-16
CA2507923C (en) 2010-02-02
AU2003292510A1 (en) 2004-07-09
PT1581538E (pt) 2007-05-31
CN1729197A (zh) 2006-02-01
CA2507923A1 (en) 2004-07-01
NO20052909L (no) 2005-09-12
BRPI0316895B8 (pt) 2019-09-03
WO2004055026A8 (en) 2005-06-23
AU2003292510B2 (en) 2009-04-23
JP4571507B2 (ja) 2010-10-27
HK1083840A1 (en) 2006-07-14
ZA200504042B (en) 2006-01-26
BR0316895A (pt) 2005-10-25
SI1581538T1 (sl) 2007-08-31
NZ540841A (en) 2008-08-29
EA009367B1 (ru) 2007-12-28
CN100378109C (zh) 2008-04-02
DE60312226D1 (de) 2007-04-12
DE60312226T2 (de) 2007-11-15
KR20050084185A (ko) 2005-08-26
WO2004055026A1 (en) 2004-07-01
EP1581538B1 (en) 2007-02-28
NO334030B1 (no) 2013-11-18
US20070142398A1 (en) 2007-06-21
BRPI0316895B1 (pt) 2018-07-24
DK1581538T3 (da) 2007-06-25
MXPA05005808A (es) 2005-09-08

Similar Documents

Publication Publication Date Title
NO20052909D0 (no) Tetracyclic 3-substituted indoles having serotonin receptor affinity.
NO20035359D0 (no) Nye indolderivater med 5-HT6-reseptoraffinitet
ATE344030T1 (de) 4-piperazinylbenzolsulfonyl-indole mit 5-ht6 rezeptor-affinität
ATE501118T1 (de) Substituierte indole
DE60320439D1 (de) Indolderivate als beta-2 agonisten
ATE340792T1 (de) Substituierte indole als alpha-1 agonisten
DE60138605D1 (de) Phenyl-substituierte indole als h3 histaminrezeptorantagonisten
DK1513832T3 (da) Indol, azaindol og relaterede heterocykliske 4-alkenylpiperidinamider
SG146683A1 (en) Fused heterocyclic compounds as serotonin receptor modulators
ATE401307T1 (de) N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
MXPA03003039A (es) Derivados de indola y bencimidazola como moduladores del receptor crf.
NO20041604L (no) 3-substituerte 4-pyrimidonderivater
NO20022803L (no) Substituerte indol-mannichbaser
EP1575493A4 (en) INDOLE, AZAINDOLE AND PIPERAZINE SULFONYLUREIDO HETEROCYCLIC DERIVATIVES
NO20026168D0 (no) 3-azabicyklo(3.1.0)heksan derivater med opioid reseptor affinitet
MXPA04000908A (es) Compuestos farmaceuticamente activos que tienen estructura de anillo de pirazolotriazolopirimidina triciclica y metodos de uso.
NO20015737L (no) Indol derivater
PT1228041E (pt) Derivados de indol
PT1068198E (pt) Indoles 5-heteroarilo substituidos
IS2431B (is) Nýjar indólafleiður
ATE300545T1 (de) Substituierte indoline als 5-ht-rezeptor liganden
AU2003281525A1 (en) Serotonin receptor
IS8002A (is) Setið indólín og indól afleiður
ATE405560T1 (de) Indolderivaten
DK1330457T3 (da) Cyclopenta[b][1,4]diazepino[6,7,1-hi]indoler som 5HT2C-antagonister

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees