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NO20051359L - Innkapslede kollagensekretoriske celler og fremgangsmate til fremstilling derav - Google Patents

Innkapslede kollagensekretoriske celler og fremgangsmate til fremstilling derav

Info

Publication number
NO20051359L
NO20051359L NO20051359A NO20051359A NO20051359L NO 20051359 L NO20051359 L NO 20051359L NO 20051359 A NO20051359 A NO 20051359A NO 20051359 A NO20051359 A NO 20051359A NO 20051359 L NO20051359 L NO 20051359L
Authority
NO
Norway
Prior art keywords
preparation
secretory cells
collagen secretory
encapsulated collagen
agarose
Prior art date
Application number
NO20051359A
Other languages
English (en)
Other versions
NO324570B1 (no
Inventor
Albert L Rubin
Kanti Jain
Original Assignee
Rogosin Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20051359L publication Critical patent/NO20051359L/no
Application filed by Rogosin Inst filed Critical Rogosin Inst
Publication of NO324570B1 publication Critical patent/NO324570B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/39Pancreas; Islets of Langerhans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012Cell encapsulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • C12N5/0677Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • C12N2533/76Agarose, agar-agar

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20051359A 1994-01-13 2005-03-16 Agaroseovertrukket, agarosekollagensektretorisk celleperle og fremgangsmate til fremstilling derav samt fremgangsmate for konservering av sekretoriske celler. NO324570B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18126994A 1994-01-13 1994-01-13
PCT/US1995/000400 WO1995019430A1 (en) 1994-01-13 1995-01-12 Macroencapsulated secretory cells

Publications (2)

Publication Number Publication Date
NO20051359L true NO20051359L (no) 1996-09-11
NO324570B1 NO324570B1 (no) 2007-11-26

Family

ID=22663563

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19962955A NO323228B1 (no) 1994-01-13 1996-07-15 En agaroseovertrukket, agarosesekretorisk celleperle, en fremgangsmate for fremstilling derav, samt en fremgangsmate for konservering av agarosesekretoriske celler.
NO20051359A NO324570B1 (no) 1994-01-13 2005-03-16 Agaroseovertrukket, agarosekollagensektretorisk celleperle og fremgangsmate til fremstilling derav samt fremgangsmate for konservering av sekretoriske celler.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO19962955A NO323228B1 (no) 1994-01-13 1996-07-15 En agaroseovertrukket, agarosesekretorisk celleperle, en fremgangsmate for fremstilling derav, samt en fremgangsmate for konservering av agarosesekretoriske celler.

Country Status (18)

Country Link
US (3) US5643569A (no)
EP (3) EP0742818B1 (no)
JP (4) JP3948742B2 (no)
KR (1) KR100474803B1 (no)
CN (1) CN1087779C (no)
AT (3) ATE275194T1 (no)
AU (1) AU681240C (no)
CA (1) CA2181156C (no)
DE (3) DE69534865T2 (no)
DK (2) DK1666585T3 (no)
ES (3) ES2309849T3 (no)
FI (1) FI118853B (no)
IL (1) IL112330A (no)
NO (2) NO323228B1 (no)
NZ (3) NZ329619A (no)
PT (3) PT742818E (no)
RU (2) RU2208636C2 (no)
WO (1) WO1995019430A1 (no)

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US5888497A (en) * 1996-04-03 1999-03-30 The Rogosin Institute Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation
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Also Published As

Publication number Publication date
PT742818E (pt) 2004-12-31
JPH09510868A (ja) 1997-11-04
AU1526795A (en) 1995-08-01
JP2006345875A (ja) 2006-12-28
RU2208636C2 (ru) 2003-07-20
JP2005137376A (ja) 2005-06-02
AU681240C (en) 2006-12-07
ATE275194T1 (de) 2004-09-15
PT1666585E (pt) 2008-12-10
US5643569A (en) 1997-07-01
IL112330A0 (en) 1995-03-30
DK1666585T3 (da) 2009-01-12
ATE320482T1 (de) 2006-04-15
EP1418228A1 (en) 2004-05-12
FI962841L (fi) 1996-09-12
DE69535842D1 (de) 2008-10-23
FI118853B (fi) 2008-04-15
DK1418228T3 (da) 2006-07-17
ES2260568T3 (es) 2006-11-01
NO962955L (no) 1996-09-11
ATE408005T1 (de) 2008-09-15
EP1666585A1 (en) 2006-06-07
CA2181156C (en) 2001-10-16
DE69533437T2 (de) 2005-09-15
EP1418228B1 (en) 2006-03-15
KR100474803B1 (ko) 2005-03-10
KR20050005235A (ko) 2005-01-13
AU681240B2 (en) 1997-08-21
NO324570B1 (no) 2007-11-26
EP0742818A4 (en) 2002-01-09
JP3948742B2 (ja) 2007-07-25
CA2181156A1 (en) 1995-07-20
DE69533437D1 (de) 2004-10-07
DE69534865T2 (de) 2006-08-17
NZ509363A (en) 2006-02-24
NZ329619A (en) 1999-09-29
WO1995019430A1 (en) 1995-07-20
FI962841A0 (fi) 1996-07-12
EP0742818A1 (en) 1996-11-20
ES2309849T3 (es) 2008-12-16
CN1087779C (zh) 2002-07-17
USRE38027E1 (en) 2003-03-11
MX9602765A (es) 1998-06-30
NZ278809A (en) 1998-03-25
JP4435134B2 (ja) 2010-03-17
RU2177503C2 (ru) 2001-12-27
PT1418228E (pt) 2006-09-29
HK1084693A1 (en) 2006-08-04
USRE40555E1 (en) 2008-10-28
NO962955D0 (no) 1996-07-15
NO323228B1 (no) 2007-02-05
DE69534865D1 (de) 2006-05-11
IL112330A (en) 1999-01-26
EP1666585B1 (en) 2008-09-10
CN1141650A (zh) 1997-01-29
JP3989492B2 (ja) 2007-10-10
ES2227544T3 (es) 2005-04-01
EP0742818B1 (en) 2004-09-01
JP2007020585A (ja) 2007-02-01

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