NO20050127D0 - 9-alpha-substituted ostratrienes as selectively active oestrogens - Google Patents

9-alpha-substituted ostratrienes as selectively active oestrogens

Info

Publication number: NO20050127D0
Authority: NO; Norway
Prior art keywords: ostratrienes; oestrogens; alpha; substituted; selectively active
Prior art date: 2002-06-11

Application number

NO20050127A

Other languages

Norwegian (no)

Other versions

NO329563B1 (en

NO20050127L (en

Inventor

Karl-Heinrich Fritzemeier

Peter Muhn

Gerd Mueller

Dirk Kosemund

Alexander Hillisch

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-11

Filing date

2005-01-10

Publication date

2005-01-10

2005-01-10 Application filed by Schering Ag filed Critical Schering Ag

2005-01-10 Publication of NO20050127D0 publication Critical patent/NO20050127D0/en

2005-03-11 Publication of NO20050127L publication Critical patent/NO20050127L/en

2010-11-15 Publication of NO329563B1 publication Critical patent/NO329563B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0055—Estrane derivatives not substituted in position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Pregnancy & Childbirth (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20050127A 2002-06-11 2005-01-10 9-alpha-substituted ostratrienes as selectively active oestrogens, pharmaceutical compositions containing the compounds, and their use in the preparation of pharmaceutical agents NO329563B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10226326A DE10226326A1 (en)	2002-06-11	2002-06-11	9-alpha-substituted estratrienes as selective estrogens
PCT/EP2003/006172 WO2003104253A2 (en)	2002-06-11	2003-06-11	9-alpha-substituted estratrienes as selectively active estrogen

Publications (3)

Publication Number	Publication Date
NO20050127D0 true NO20050127D0 (en)	2005-01-10
NO20050127L NO20050127L (en)	2005-03-11
NO329563B1 NO329563B1 (en)	2010-11-15

Family

ID=29723144

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20050127A NO329563B1 (en)	2002-06-11	2005-01-10	9-alpha-substituted ostratrienes as selectively active oestrogens, pharmaceutical compositions containing the compounds, and their use in the preparation of pharmaceutical agents

Country Status (28)

Country	Link
EP (1)	EP1517914B1 (en)
JP (1)	JP4615998B2 (en)
KR (1)	KR101006612B1 (en)
CN (1)	CN1293090C (en)
AR (1)	AR040188A1 (en)
AT (1)	ATE303397T1 (en)
AU (1)	AU2003242683B9 (en)
BR (1)	BR0312140A (en)
CA (1)	CA2486495C (en)
CR (1)	CR10289A (en)
CU (1)	CU23414B7 (en)
DE (2)	DE10226326A1 (en)
DK (1)	DK1517914T3 (en)
EA (1)	EA008442B1 (en)
EC (1)	ECSP055530A (en)
ES (1)	ES2248770T3 (en)
HR (1)	HRP20050009B1 (en)
IL (1)	IL165321A (en)
MX (1)	MXPA04012491A (en)
NO (1)	NO329563B1 (en)
PE (1)	PE20040613A1 (en)
PL (1)	PL209910B1 (en)
RS (1)	RS50878B (en)
TW (1)	TWI286140B (en)
UA (1)	UA78062C2 (en)
UY (1)	UY27844A1 (en)
WO (1)	WO2003104253A2 (en)
ZA (1)	ZA200500217B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10027887A1 (en)	2000-05-31	2001-12-13	Jenapharm Gmbh	Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds
PL1689410T3 (en) *	2003-11-26	2008-10-31	Bayer Schering Pharma Ag	Prevention and treatment of hypertensive heart diseases by the selective estrogens 8beta-vinyl-estra-1,3,5(10)-trien-3,17beta-diol and 17beta-fluor-9alpha-vinyl-estra-1,3,5(10)-trien-3,16alpha-diol
US7534780B2 (en)	2004-05-21	2009-05-19	Bayer Schering Pharma Aktiengesellschaft	Estradiol prodrugs
DE102005057224A1 (en) *	2005-11-29	2007-05-31	Bayer Schering Pharma Ag	New 9-alpha substituted estratriene derivatives esterified with a sulfamoylphenyl-substituted acid residue, are prodrugs useful as carboanhydrase inhibitors for treating estrogen deficiency disorders
CN102006857B (en) *	2008-02-13	2013-06-26	拜耳先灵医药股份有限公司	Drug delivery system with stabilising effect
EP2143432A1 (en)	2008-07-11	2010-01-13	Bayer Schering Pharma AG	9-alpha estratriene derivatives as ER-beta selective ligands for the prevention and treatment of intestinal cancer
CN102215818A (en) *	2008-11-21	2011-10-12	拜耳先灵医药股份有限公司	Drug delivery system
AU2015308987B2 (en)	2014-08-26	2021-02-18	Kaass Discovery As	Methods, agents and compositions for treatment of inflammatory conditions
CN113056473A (en) *	2018-09-07	2021-06-29	达特茅斯学院托管理事会	C19 scaffolds and steroids and methods of use and manufacture thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2336432A1 (en) *	1973-07-13	1975-01-30	Schering Ag	3.17.18-TRIHYDROXY-1.3.5 (10) -OESTRATRIENE
US6154158A (en) *	1998-06-30	2000-11-28	Qualcomm Incorporated	Digital-to-analog converter D.C. offset correction comparing converter input and output signals
DE19906159A1 (en) *	1999-02-09	2000-08-10	Schering Ag	16-hydroxyestratrienes as selectively active estrogens
AU1855201A (en) *	1999-11-02	2001-05-14	Schering Aktiengesellschaft	18-nor-steroids as selectively active estrogens
AU5834101A (en) *	2000-04-12	2001-10-23	Schering Ag	8ss-hydrocarbyl-substituted estratrienes for use as selective estrogens

2002
- 2002-06-11 DE DE10226326A patent/DE10226326A1/en not_active Ceased
2003
- 2003-06-10 PE PE2003000575A patent/PE20040613A1/en not_active Application Discontinuation
- 2003-06-11 JP JP2004511321A patent/JP4615998B2/en not_active Expired - Fee Related
- 2003-06-11 AU AU2003242683A patent/AU2003242683B9/en not_active Ceased
- 2003-06-11 ES ES03757065T patent/ES2248770T3/en not_active Expired - Lifetime
- 2003-06-11 EP EP03757065A patent/EP1517914B1/en not_active Expired - Lifetime
- 2003-06-11 EA EA200401544A patent/EA008442B1/en not_active IP Right Cessation
- 2003-06-11 KR KR1020047020133A patent/KR101006612B1/en not_active Expired - Fee Related
- 2003-06-11 WO PCT/EP2003/006172 patent/WO2003104253A2/en not_active Ceased
- 2003-06-11 CN CNB038135027A patent/CN1293090C/en not_active Expired - Fee Related
- 2003-06-11 RS YUP-1070/04A patent/RS50878B/en unknown
- 2003-06-11 TW TW092115863A patent/TWI286140B/en not_active IP Right Cessation
- 2003-06-11 AT AT03757065T patent/ATE303397T1/en active
- 2003-06-11 UY UY27844A patent/UY27844A1/en not_active Application Discontinuation
- 2003-06-11 AR ARP030102079A patent/AR040188A1/en active IP Right Grant
- 2003-06-11 DE DE50301116T patent/DE50301116D1/en not_active Expired - Lifetime
- 2003-06-11 CA CA2486495A patent/CA2486495C/en not_active Expired - Fee Related
- 2003-06-11 BR BR0312140-2A patent/BR0312140A/en not_active IP Right Cessation
- 2003-06-11 PL PL373090A patent/PL209910B1/en not_active IP Right Cessation
- 2003-06-11 MX MXPA04012491A patent/MXPA04012491A/en active IP Right Grant
- 2003-06-11 DK DK03757065T patent/DK1517914T3/en active
- 2003-06-11 HR HRP20050009AA patent/HRP20050009B1/en not_active IP Right Cessation
- 2003-11-06 UA UAA200500212A patent/UA78062C2/en unknown
2004
- 2004-11-22 IL IL165321A patent/IL165321A/en not_active IP Right Cessation
- 2004-12-10 CU CU20040282A patent/CU23414B7/en not_active IP Right Cessation
2005
- 2005-01-10 NO NO20050127A patent/NO329563B1/en not_active IP Right Cessation
- 2005-01-10 EC EC2005005530A patent/ECSP055530A/en unknown
2006
- 2006-01-10 ZA ZA200500217A patent/ZA200500217B/en unknown
2008
- 2008-09-16 CR CR10289A patent/CR10289A/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
HRP20050009B1 (en)	2013-07-31
DE50301116D1 (en)	2005-10-06
CA2486495C (en)	2011-04-19
EA200401544A1 (en)	2005-06-30
HRP20050009A2 (en)	2005-04-30
JP4615998B2 (en)	2011-01-19
ZA200500217B (en)	2006-03-29
WO2003104253A2 (en)	2003-12-18
CR10289A (en)	2008-11-26
AU2003242683B2 (en)	2009-07-02
EP1517914A2 (en)	2005-03-30
ES2248770T3 (en)	2006-03-16
CA2486495A1 (en)	2003-12-18
ECSP055530A (en)	2005-03-10
RS107004A (en)	2006-10-27
RS50878B (en)	2010-08-31
CN1293090C (en)	2007-01-03
KR101006612B1 (en)	2011-01-10
ATE303397T1 (en)	2005-09-15
DK1517914T3 (en)	2006-01-16
EA008442B1 (en)	2007-06-29
PL209910B1 (en)	2011-11-30
PL373090A1 (en)	2005-08-08
AU2003242683B9 (en)	2009-08-27
TW200407331A (en)	2004-05-16
IL165321A (en)	2009-08-03
KR20050009745A (en)	2005-01-25
EP1517914B1 (en)	2005-08-31
MXPA04012491A (en)	2005-06-08
DE10226326A1 (en)	2004-01-15
AU2003242683A1 (en)	2003-12-22
AR040188A1 (en)	2005-03-16
UY27844A1 (en)	2003-12-31
NO329563B1 (en)	2010-11-15
PE20040613A1 (en)	2004-12-01
JP2005533053A (en)	2005-11-04
TWI286140B (en)	2007-09-01
HK1081203A1 (en)	2006-05-12
NO20050127L (en)	2005-03-11
CN1659181A (en)	2005-08-24
UA78062C2 (en)	2007-02-15
CU23414B7 (en)	2009-09-08
WO2003104253A3 (en)	2004-09-16
BR0312140A (en)	2005-04-05

Publication	Publication Date	Title
DK3473251T3 (en)	2024-01-22	NICOTINE-CELLULOSE COMBINATION
ATE457980T1 (en)	2010-03-15	ARYLOXIMES
ATE534648T1 (en)	2011-12-15	C-6-MODIFIED INDAZOLYLPYRROLOTRIAZINES
ATE318817T1 (en)	2006-03-15	AZA-ARYLPIPERAZINE
ATE427876T1 (en)	2009-04-15	HOVERBOAT
DE50212360D1 (en)	2008-07-24	Anfahrhilfesteuerungsvorrichtung
DE50212349D1 (en)	2008-07-17	HIRURGIE
DE50301200D1 (en)	2005-10-20	WISCHBLATT
ATE349458T1 (en)	2007-01-15	ETONOGESTRELESTER
DK1556377T3 (en)	2006-10-23	Cyclopropylthienylcarboxamides as fungicides
DE50302660D1 (en)	2006-05-11	Stopfmachine
DE50301960D1 (en)	2006-01-26	hydromount
NO20050127L (en)	2005-03-11	9-alpha-substituted ostratrienes as selectively active oestrogens
DE50301464D1 (en)	2005-12-01	threadlocking
ATA4142004A (en)	2005-12-15	TRÄGERVERBAU
NO20043664L (en)	2004-09-01	New procedure
ATE469773T1 (en)	2010-06-15	ZUGÖSE
DE50303317D1 (en)	2006-06-14	SLOT-BREAKER
ATA19152002A (en)	2004-11-15	HUBKUPPLUNG
DE60205924T2 (en)	2006-06-14	microgrippers
DE50209283D1 (en)	2007-03-08	Dripline
ITMI20021327A1 (en)	2003-12-15	NEW OSSIALCHILPIPERAZINE
ATE396192T1 (en)	2008-06-15	N-SULFONYLAMINOTHIAZOLES
FR2840006B1 (en)	2005-01-21	DEMONABLE CONSTRUCTION
DE10244834B8 (en)	2005-01-13	susceptometer

Legal Events

Date	Code	Title	Description
2012-12-17	CHAD	Change of the owner's name or address (par. 44 patent law, par. patentforskriften)	Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE
2015-01-26	MM1K	Lapsed by not paying the annual fees