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NO20050019L - Polytylenglykolaldehyd derivatives - Google Patents

Polytylenglykolaldehyd derivatives

Info

Publication number
NO20050019L
NO20050019L NO20050019A NO20050019A NO20050019L NO 20050019 L NO20050019 L NO 20050019L NO 20050019 A NO20050019 A NO 20050019A NO 20050019 A NO20050019 A NO 20050019A NO 20050019 L NO20050019 L NO 20050019L
Authority
NO
Norway
Prior art keywords
polytylenglykolaldehyd
derivatives
compounds
preparation
methods
Prior art date
Application number
NO20050019A
Other languages
Norwegian (no)
Other versions
NO336974B1 (en
Inventor
Chee-Youb Won
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20050019L publication Critical patent/NO20050019L/en
Publication of NO336974B1 publication Critical patent/NO336974B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
    • C08G65/324—Polymers modified by chemical after-treatment with inorganic compounds containing oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
    • C08G65/2615—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen the other compounds containing carboxylic acid, ester or anhydride groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2618—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen
    • C08G65/2621—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups
    • C08G65/2624—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups containing aliphatic amine groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Polyetylenglykolaldehydforbindelser blir tilveiebrakt. Fremgangsmåter for fremstilling og anvendelse av slike forbindelser, så vel som kjemiske mellomprodukter blir også tilveiebrakt.Polyethylene glycol aldehyde compounds are provided. Methods for the preparation and use of such compounds as well as chemical intermediates are also provided.

NO20050019A 2002-07-24 2005-01-03 Polyethylene glycol aldehyde derivatives and process for their preparation NO336974B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39819602P 2002-07-24 2002-07-24
PCT/EP2003/007734 WO2004013205A1 (en) 2002-07-24 2003-07-16 Polyethylene glycol aldehyde derivatives

Publications (2)

Publication Number Publication Date
NO20050019L true NO20050019L (en) 2005-02-23
NO336974B1 NO336974B1 (en) 2015-12-07

Family

ID=31495721

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050019A NO336974B1 (en) 2002-07-24 2005-01-03 Polyethylene glycol aldehyde derivatives and process for their preparation

Country Status (28)

Country Link
US (2) US7273909B2 (en)
EP (1) EP1539857B1 (en)
JP (1) JP4071238B2 (en)
KR (1) KR100615753B1 (en)
CN (1) CN1671769B (en)
AR (1) AR040607A1 (en)
AT (1) ATE344289T1 (en)
AU (1) AU2003250971B2 (en)
BR (1) BR0312863B1 (en)
CA (1) CA2493221C (en)
DE (1) DE60309482T2 (en)
DK (1) DK1539857T3 (en)
ES (1) ES2274277T3 (en)
GT (1) GT200300154A (en)
HR (1) HRP20050026A2 (en)
IL (1) IL165920A0 (en)
JO (1) JO2400B1 (en)
MX (1) MXPA05000799A (en)
NO (1) NO336974B1 (en)
PA (1) PA8577601A1 (en)
PE (1) PE20040703A1 (en)
PL (1) PL214871B1 (en)
PT (1) PT1539857E (en)
RU (1) RU2288212C2 (en)
TW (1) TWI276647B (en)
UY (1) UY27902A1 (en)
WO (1) WO2004013205A1 (en)
ZA (1) ZA200410296B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4959133B2 (en) 2002-09-09 2012-06-20 ネクター セラピューティックス Method for preparing water-soluble polymer derivative having terminal carboxylic acid or ester thereof
AU2003270454B2 (en) * 2002-09-09 2010-05-20 Nektar Therapeutics Water-soluble polymer alkanals
US20050214250A1 (en) * 2003-11-06 2005-09-29 Harris J M Method of preparing carboxylic acid functionalized polymers
US7989554B2 (en) * 2006-01-10 2011-08-02 Enzon Pharmaceuticals, Inc. Reacting polyalkylene oxide with base, tertiary alkyl haloacetate, then acid to prepare polyalkylene oxide carboxylic acid
WO2008051383A2 (en) * 2006-10-19 2008-05-02 Amgen Inc. Use of alcohol co-solvents to improve pegylation reaction yields
WO2008048079A1 (en) * 2006-10-20 2008-04-24 Postech Academy-Industry Foundation Long acting formulation of biopharmaceutical
US8247493B2 (en) * 2007-10-22 2012-08-21 Postech Academy-Industry Foundation Long acting formulation of biopharmaceutical
KR100967833B1 (en) * 2008-05-20 2010-07-05 아이디비켐(주) Method for producing high purity polyethylene glycol aldehyde derivative
JP5766118B2 (en) * 2008-09-11 2015-08-19 ウェルズ ファーゴ バンク ナショナル アソシエイション Polymeric alpha-hydroxyaldehyde and ketone reagents and conjugation methods
RU2439091C1 (en) * 2010-10-06 2012-01-10 Общество С Ограниченной Ответственностью "Форт" (Ооо "Форт") Polyethylene glycol derivatives containing aromatic diazo group
EP2592103A1 (en) 2011-11-08 2013-05-15 Adriacell S.p.A. Polymer aldehyde derivatives
KR101641206B1 (en) * 2013-06-24 2016-07-22 에이비엘바이오 주식회사 An antibody-drug conjugate having improved stability, and use thereof
TWI689310B (en) * 2014-07-11 2020-04-01 巨生生醫股份有限公司 Method of treating iron deficiency
KR102247701B1 (en) 2016-02-26 2021-05-03 한미정밀화학주식회사 Method for preparing polyethylene glycol dialdehyde derivatives
US11603346B2 (en) 2016-03-07 2023-03-14 Hanmi Pharm. Co., Ltd. Polyethylene glycol derivative and use thereof
EP3689942B1 (en) * 2017-09-29 2024-06-19 Hanmi Pharm. Co., Ltd. Protein complex comprising non-peptidyl polymer-coupled fatty acid derivative compound as linker and preparation method therefor
EP4448556A1 (en) 2021-12-16 2024-10-23 RDP Pharma AG Cell penetrating polypeptides (cpps) and their use in human therapy
EP4480497A1 (en) 2023-06-21 2024-12-25 RDP Pharma AG Bio-conjugates for oncology

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252714A (en) * 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
US5770577A (en) * 1994-11-14 1998-06-23 Amgen Inc. BDNF and NT-3 polypeptides selectively linked to polyethylene glycol
CH690143A5 (en) 1995-01-27 2000-05-15 Rieter Automotive Int Ag Lambda / 4 sound absorbers.
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5990237A (en) 1997-05-21 1999-11-23 Shearwater Polymers, Inc. Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
WO2000024697A1 (en) * 1998-10-26 2000-05-04 University Of Utah Research Foundation Method for preparation of polyethylene glycol aldehyde derivatives
JO2291B1 (en) 1999-07-02 2005-09-12 اف . هوفمان لاروش ايه جي Erythopintin derivatives
KR100488351B1 (en) 2001-12-11 2005-05-11 선바이오(주) Novel polyethylene glycol-propionaldehyde derivatives
EP1507755A4 (en) 2001-12-11 2006-05-17 Sun Bio Inc Novel monofunctional polyethylene glycol aldehydes

Also Published As

Publication number Publication date
DK1539857T3 (en) 2007-03-12
JP4071238B2 (en) 2008-04-02
WO2004013205A1 (en) 2004-02-12
AR040607A1 (en) 2005-04-13
CN1671769B (en) 2010-05-12
UY27902A1 (en) 2003-12-31
BR0312863B1 (en) 2013-02-05
HRP20050026A2 (en) 2006-02-28
TW200416241A (en) 2004-09-01
EP1539857B1 (en) 2006-11-02
RU2288212C2 (en) 2006-11-27
IL165920A0 (en) 2006-01-15
TWI276647B (en) 2007-03-21
DE60309482D1 (en) 2006-12-14
ATE344289T1 (en) 2006-11-15
KR100615753B1 (en) 2006-08-25
AU2003250971B2 (en) 2008-04-03
AU2003250971A1 (en) 2004-02-23
NO336974B1 (en) 2015-12-07
JO2400B1 (en) 2007-06-17
PL214871B1 (en) 2013-09-30
BR0312863A (en) 2005-06-14
CN1671769A (en) 2005-09-21
ES2274277T3 (en) 2007-05-16
PE20040703A1 (en) 2004-10-14
CA2493221A1 (en) 2004-02-12
KR20050025974A (en) 2005-03-14
EP1539857A1 (en) 2005-06-15
PA8577601A1 (en) 2004-02-07
US20040019157A1 (en) 2004-01-29
DE60309482T2 (en) 2007-06-28
PL375266A1 (en) 2005-11-28
US20070167606A1 (en) 2007-07-19
GT200300154A (en) 2004-03-15
JP2005533913A (en) 2005-11-10
PT1539857E (en) 2007-01-31
ZA200410296B (en) 2006-07-26
MXPA05000799A (en) 2005-04-19
RU2005105568A (en) 2005-10-20
US7273909B2 (en) 2007-09-25
CA2493221C (en) 2008-11-18

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