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NO20044186L - Peptid-deformylaseinhibitorer - Google Patents

Peptid-deformylaseinhibitorer

Info

Publication number
NO20044186L
NO20044186L NO20044186A NO20044186A NO20044186L NO 20044186 L NO20044186 L NO 20044186L NO 20044186 A NO20044186 A NO 20044186A NO 20044186 A NO20044186 A NO 20044186A NO 20044186 L NO20044186 L NO 20044186L
Authority
NO
Norway
Prior art keywords
deformylaseinhibitorer
peptide
novel
pdf inhibitors
methods
Prior art date
Application number
NO20044186A
Other languages
English (en)
Other versions
NO328933B1 (no
Inventor
Jack Dale Leber
Kelly M Aubart
Siegfried B Christensen
Ajita Bhat
Xiangmin Liao
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20044186L publication Critical patent/NO20044186L/no
Publication of NO328933B1 publication Critical patent/NO328933B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20044186A 2002-03-13 2004-09-30 Peptid-deformylaseinhibitorer NO328933B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36442302P 2002-03-13 2002-03-13
PCT/US2003/007509 WO2003077913A1 (en) 2002-03-13 2003-03-13 Peptide deformylase inhibitors

Publications (2)

Publication Number Publication Date
NO20044186L true NO20044186L (no) 2004-09-30
NO328933B1 NO328933B1 (no) 2010-06-21

Family

ID=28041913

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044186A NO328933B1 (no) 2002-03-13 2004-09-30 Peptid-deformylaseinhibitorer

Country Status (20)

Country Link
US (2) US20050124677A1 (no)
EP (1) EP1482930B1 (no)
JP (1) JP4471663B2 (no)
KR (1) KR100980145B1 (no)
CN (1) CN100336809C (no)
AT (1) ATE514683T1 (no)
AU (1) AU2003216554A1 (no)
BR (1) BR0308321A (no)
CA (1) CA2478331A1 (no)
ES (1) ES2366396T3 (no)
IL (1) IL163899A0 (no)
IS (1) IS7441A (no)
MX (1) MXPA04008799A (no)
NO (1) NO328933B1 (no)
NZ (1) NZ534839A (no)
PL (1) PL371016A1 (no)
RU (1) RU2287525C2 (no)
TW (1) TWI294778B (no)
WO (1) WO2003077913A1 (no)
ZA (1) ZA200406973B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208595B2 (en) * 2003-07-25 2007-04-24 The Ohio State University Research Foundation Peptide deformylase inhibitors as novel antibiotics
US7705037B2 (en) * 2005-06-07 2010-04-27 Novartis Ag 1-substituted pyrrolidin-2-ones and use thereof as peptide deformylase inhibitors
BRPI0815634B1 (pt) * 2007-08-21 2024-01-09 Firmenich Incorporated Receptores t2r humanos que respondem a compostos amargos que causam gosto amargo nas composições e seus métodos de produção, bem como método de redução ou alívio do sabor amargo em uma composição, composição de alimento, bebida ou medicamento ou composição de um produto nãocomestível
DE102009045969B4 (de) * 2009-10-23 2019-01-31 Technische Universität Bergakademie Freiberg Verfahren und Mittel zur Spaltung von Estern, Amiden und Thioestern der Ameisensäure

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
TW448172B (en) * 1996-03-08 2001-08-01 Pharmacia & Upjohn Co Llc Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation
JP3382127B2 (ja) * 1996-07-04 2003-03-04 エフ.ホフマン−ラ ロシュ アーゲー キラルなコハク酸誘導体の製造方法
CA2361848A1 (en) * 1999-04-02 2000-10-12 Dupont Pharmaceuticals Company Novel lactam inhibitors of matrix metalloproteinases, tnf-.alpha., and aggrecanase
AU2002230385A1 (en) 2000-09-25 2002-04-15 Questcor Pharmaceuticals, Inc. Peptide deformylase inhibitors
EP1355901A2 (en) * 2001-01-11 2003-10-29 Bristol-Myers Squibb Pharma Company 1,1-DISUBSTITUTED CYCLIC INHIBITORS OF MATRIX METALLOPROTEASE AND TNF-$g(a)

Also Published As

Publication number Publication date
EP1482930B1 (en) 2011-06-29
ZA200406973B (en) 2005-06-23
RU2004130454A (ru) 2005-04-10
PL371016A1 (en) 2005-06-13
AU2003216554A1 (en) 2003-09-29
NO328933B1 (no) 2010-06-21
KR20040091120A (ko) 2004-10-27
US7745637B2 (en) 2010-06-29
JP2005525383A (ja) 2005-08-25
ES2366396T3 (es) 2011-10-19
MXPA04008799A (es) 2004-11-26
KR100980145B1 (ko) 2010-09-03
CN1652775A (zh) 2005-08-10
TW200405810A (en) 2004-04-16
TWI294778B (en) 2008-03-21
EP1482930A1 (en) 2004-12-08
NZ534839A (en) 2006-09-29
WO2003077913A1 (en) 2003-09-25
ATE514683T1 (de) 2011-07-15
US20070155810A1 (en) 2007-07-05
EP1482930A4 (en) 2006-06-28
BR0308321A (pt) 2004-12-28
CA2478331A1 (en) 2003-09-25
IL163899A0 (en) 2005-12-18
IS7441A (is) 2004-09-08
CN100336809C (zh) 2007-09-12
US20050124677A1 (en) 2005-06-09
RU2287525C2 (ru) 2006-11-20
JP4471663B2 (ja) 2010-06-02

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