NO20044138L - Crystalline polymorphic form of irinotecan hydrochloride - Google Patents
Crystalline polymorphic form of irinotecan hydrochlorideInfo
- Publication number
- NO20044138L NO20044138L NO20044138A NO20044138A NO20044138L NO 20044138 L NO20044138 L NO 20044138L NO 20044138 A NO20044138 A NO 20044138A NO 20044138 A NO20044138 A NO 20044138A NO 20044138 L NO20044138 L NO 20044138L
- Authority
- NO
- Norway
- Prior art keywords
- polymorphic form
- irinotecan hydrochloride
- crystalline polymorphic
- crystalline
- irinotecan
- Prior art date
Links
- 229960000779 irinotecan hydrochloride Drugs 0.000 title 1
- GURKHSYORGJETM-WAQYZQTGSA-N irinotecan hydrochloride (anhydrous) Chemical compound Cl.C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 GURKHSYORGJETM-WAQYZQTGSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36068402P | 2002-03-01 | 2002-03-01 | |
| PCT/EP2003/001948 WO2003074527A1 (en) | 2002-03-01 | 2003-02-26 | Crystalline polymorphic form of irinotecan hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20044138L true NO20044138L (en) | 2004-11-29 |
Family
ID=27789001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20044138A NO20044138L (en) | 2002-03-01 | 2004-09-29 | Crystalline polymorphic form of irinotecan hydrochloride |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1487840B1 (en) |
| JP (1) | JP2005525367A (en) |
| KR (1) | KR20040091083A (en) |
| CN (1) | CN1276923C (en) |
| AR (1) | AR038618A1 (en) |
| AT (1) | ATE364610T1 (en) |
| AU (1) | AU2003215594A1 (en) |
| BR (1) | BR0308133A (en) |
| CA (1) | CA2477926A1 (en) |
| DE (1) | DE60314378T2 (en) |
| DK (1) | DK1487840T3 (en) |
| ES (1) | ES2287495T3 (en) |
| IL (1) | IL163820A0 (en) |
| MX (1) | MXPA04008484A (en) |
| NO (1) | NO20044138L (en) |
| NZ (1) | NZ534999A (en) |
| PE (1) | PE20030923A1 (en) |
| PL (1) | PL372318A1 (en) |
| PT (1) | PT1487840E (en) |
| RU (1) | RU2300535C2 (en) |
| TW (1) | TWI270374B (en) |
| WO (1) | WO2003074527A1 (en) |
| ZA (1) | ZA200406927B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1598356A4 (en) * | 2003-02-25 | 2008-07-02 | Yakult Honsha Kk | PROCESS FOR THE PREPARATION OF IRINOTECANE HYDROCHLORIDE POLYMORPHISM |
| ES2245891B1 (en) * | 2004-07-09 | 2006-11-16 | Clinmet S.L. | "METHOD FOR OBTAINING A UNIVERSAL EXCIPIENT FOR ORAL ADMINISTRATION OF PHARMACEUTICAL ACTIVE PRINCIPLES AND COMPOSITIONS OF EXCIPIENTS RESULTING FROM THE METHOD". |
| JP5491699B2 (en) | 2004-12-21 | 2014-05-14 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | Stereoselective methods and crystalline forms of camptothecin |
| WO2006082279A1 (en) | 2005-02-07 | 2006-08-10 | Fermion Oy | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
| PL1846371T3 (en) | 2005-02-08 | 2014-01-31 | Fermion Oy | Process for producing [1,4']bipiperidinyl-1'-carbonyl chloride or hydrochloride thereof |
| CA2591074C (en) | 2005-02-08 | 2015-01-20 | Fermion Oy | Preparation method |
| KR101150504B1 (en) * | 2005-09-20 | 2012-07-09 | 시노팜 싱가포르 피티이 리미티드 | Novel crystal forms of irinotecan hydrochloride |
| CN101318964B (en) * | 2007-06-07 | 2010-12-15 | 上海迪赛诺医药发展有限公司 | Novel crystal system of irinotecan hydrochloride and preparation method thereof |
| FR2918279B1 (en) * | 2007-07-05 | 2010-10-22 | Aventis Pharma Sa | ANTITUMOR COMBINATIONS CONTAINING A VEGF INHIBITOR AGENT AND IRINOTECAN |
| IT1391757B1 (en) * | 2008-11-11 | 2012-01-27 | Antibioticos Spa | IRINOTECAN CRYSTALLINE CHLORIDRATE AND METHODS FOR ITS PREPARATION |
| CN101659667B (en) * | 2009-09-07 | 2011-11-02 | 重庆泰濠制药有限公司 | Method for purifying irinotecan hydrochloride |
| US8546573B2 (en) | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| JO3283B1 (en) | 2011-04-26 | 2018-09-16 | Sanofi Sa | Composition including Afflipersept, Folinic Acid, 5- Fluorouracil (5- Fu) and Irenosetan (FOLFIRI) |
| CN102866126B (en) * | 2011-07-05 | 2016-03-23 | 重庆华邦制药有限公司 | A kind of method of crystal form ratio in quantitative measurement compound |
| CN102311443B (en) * | 2011-08-24 | 2014-07-16 | 上海北卡医药技术有限公司 | Novel crystal form of irinotecan hydrochloride and preparation method thereof |
| RU2529831C2 (en) * | 2012-11-30 | 2014-09-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский университет дружбы народов" (РУДН) | Method of treating colon cancer |
| PT3170005T (en) | 2014-07-18 | 2019-07-16 | Sanofi Sa | Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer |
| KR102293907B1 (en) * | 2015-06-30 | 2021-08-26 | 한미약품 주식회사 | Solid formulation for for oral administration containing irinotecan and a process for the preparation thereof |
| KR102066402B1 (en) * | 2017-12-22 | 2020-01-15 | 대화제약 주식회사 | Pharmaceutical composition for oral administration comprising irinotecan or its pharmaceutically acceptable salt |
| US10919905B2 (en) * | 2019-05-16 | 2021-02-16 | Scinopharm Taiwan, Ltd. | Polymorphism for irinotecan free base |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019790A (en) * | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | Novel camptothecin derivative |
| IT1282673B1 (en) * | 1996-02-23 | 1998-03-31 | Ist Naz Stud Cura Dei Tumori | CAMPTOTECIN DERIVATIVES AND THEIR USE AS ANTI-CANCER AGENTS |
| GB9918885D0 (en) * | 1999-08-10 | 1999-10-13 | Pharmacia & Upjohn Spa | Pharmaceutical formulations in hydroxypropymethycellulose capsules |
-
2003
- 2003-02-26 MX MXPA04008484A patent/MXPA04008484A/en not_active Application Discontinuation
- 2003-02-26 EP EP03743335A patent/EP1487840B1/en not_active Expired - Lifetime
- 2003-02-26 IL IL16382003A patent/IL163820A0/en unknown
- 2003-02-26 PL PL03372318A patent/PL372318A1/en not_active Application Discontinuation
- 2003-02-26 DE DE60314378T patent/DE60314378T2/en not_active Expired - Fee Related
- 2003-02-26 ES ES03743335T patent/ES2287495T3/en not_active Expired - Lifetime
- 2003-02-26 RU RU2004129307/04A patent/RU2300535C2/en not_active IP Right Cessation
- 2003-02-26 AU AU2003215594A patent/AU2003215594A1/en not_active Abandoned
- 2003-02-26 KR KR10-2004-7013621A patent/KR20040091083A/en not_active Withdrawn
- 2003-02-26 PT PT03743335T patent/PT1487840E/en unknown
- 2003-02-26 CN CNB038072726A patent/CN1276923C/en not_active Expired - Fee Related
- 2003-02-26 CA CA002477926A patent/CA2477926A1/en not_active Abandoned
- 2003-02-26 AT AT03743335T patent/ATE364610T1/en not_active IP Right Cessation
- 2003-02-26 WO PCT/EP2003/001948 patent/WO2003074527A1/en not_active Ceased
- 2003-02-26 NZ NZ534999A patent/NZ534999A/en unknown
- 2003-02-26 JP JP2003572995A patent/JP2005525367A/en not_active Withdrawn
- 2003-02-26 BR BR0308133-8A patent/BR0308133A/en not_active IP Right Cessation
- 2003-02-26 DK DK03743335T patent/DK1487840T3/en active
- 2003-02-27 TW TW092104194A patent/TWI270374B/en not_active IP Right Cessation
- 2003-02-28 PE PE2003000196A patent/PE20030923A1/en not_active Application Discontinuation
- 2003-02-28 AR ARP030100656A patent/AR038618A1/en unknown
-
2004
- 2004-08-31 ZA ZA200406927A patent/ZA200406927B/en unknown
- 2004-09-29 NO NO20044138A patent/NO20044138L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2287495T3 (en) | 2007-12-16 |
| RU2004129307A (en) | 2005-04-10 |
| MXPA04008484A (en) | 2004-12-06 |
| BR0308133A (en) | 2005-01-04 |
| NZ534999A (en) | 2007-03-30 |
| DE60314378T2 (en) | 2008-02-28 |
| AR038618A1 (en) | 2005-01-19 |
| CN1276923C (en) | 2006-09-27 |
| EP1487840A1 (en) | 2004-12-22 |
| EP1487840B1 (en) | 2007-06-13 |
| DE60314378D1 (en) | 2007-07-26 |
| IL163820A0 (en) | 2005-12-18 |
| PL372318A1 (en) | 2005-07-11 |
| HK1075044A1 (en) | 2005-12-02 |
| JP2005525367A (en) | 2005-08-25 |
| DK1487840T3 (en) | 2007-07-16 |
| AU2003215594A1 (en) | 2003-09-16 |
| ZA200406927B (en) | 2006-06-28 |
| CA2477926A1 (en) | 2003-09-12 |
| ATE364610T1 (en) | 2007-07-15 |
| RU2300535C2 (en) | 2007-06-10 |
| PE20030923A1 (en) | 2003-10-29 |
| TW200303753A (en) | 2003-09-16 |
| PT1487840E (en) | 2007-09-11 |
| KR20040091083A (en) | 2004-10-27 |
| WO2003074527A1 (en) | 2003-09-12 |
| TWI270374B (en) | 2007-01-11 |
| CN1642958A (en) | 2005-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |