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NO20043099L - Azaindolylalkylamin-derivater som 5-hydroksytryptamin-6-ligander - Google Patents

Azaindolylalkylamin-derivater som 5-hydroksytryptamin-6-ligander

Info

Publication number
NO20043099L
NO20043099L NO20043099A NO20043099A NO20043099L NO 20043099 L NO20043099 L NO 20043099L NO 20043099 A NO20043099 A NO 20043099A NO 20043099 A NO20043099 A NO 20043099A NO 20043099 L NO20043099 L NO 20043099L
Authority
NO
Norway
Prior art keywords
hydroxytryptamine
ligands
azaindolylalkylamine
derivatives
azaindolylalkylamine derivatives
Prior art date
Application number
NO20043099A
Other languages
English (en)
Norwegian (no)
Inventor
Derek Cecil Cole
Ronald Charles Bernotas
William Joseph Lennox
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20043099L publication Critical patent/NO20043099L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20043099A 2001-12-20 2004-07-19 Azaindolylalkylamin-derivater som 5-hydroksytryptamin-6-ligander NO20043099L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34283801P 2001-12-20 2001-12-20
PCT/US2002/040220 WO2003053970A1 (fr) 2001-12-20 2002-12-17 Derives d'azaindolylalkylamine en tant que ligands de 5-hydroxytryptamine-6

Publications (1)

Publication Number Publication Date
NO20043099L true NO20043099L (no) 2004-08-17

Family

ID=23343489

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043099A NO20043099L (no) 2001-12-20 2004-07-19 Azaindolylalkylamin-derivater som 5-hydroksytryptamin-6-ligander

Country Status (22)

Country Link
US (3) US6800640B2 (fr)
EP (1) EP1456206B1 (fr)
JP (1) JP4339123B2 (fr)
KR (1) KR20040077861A (fr)
CN (1) CN1620455A (fr)
AR (1) AR037907A1 (fr)
AT (1) ATE396191T1 (fr)
AU (1) AU2002360618B2 (fr)
BR (1) BR0215151A (fr)
CA (1) CA2470832C (fr)
CO (1) CO5590960A2 (fr)
DE (1) DE60226775D1 (fr)
DK (1) DK1456206T3 (fr)
ES (1) ES2305338T3 (fr)
IL (1) IL162242A0 (fr)
MX (1) MXPA04005886A (fr)
NO (1) NO20043099L (fr)
PL (1) PL370890A1 (fr)
RU (1) RU2004122094A (fr)
TW (1) TW200301251A (fr)
WO (1) WO2003053970A1 (fr)
ZA (1) ZA200405733B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2222828B1 (es) 2003-07-30 2006-04-16 Laboratorios Del Dr. Esteve, S.A. Derivados de 1-sulfonilindoles, su preparacion y su aplicacion como medicamentos.
CA2548172A1 (fr) 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines utiles comme inhibiteurs des proteines kinases
WO2005121140A1 (fr) 2004-06-09 2005-12-22 Glaxo Group Limited Derives de pyrrolopyridine
JP4989477B2 (ja) * 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｃ］ピリジン誘導体及びその製造方法
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
KR101142363B1 (ko) 2005-06-27 2012-05-21 주식회사유한양행 피롤로피리딘 유도체를 포함하는 항암제 조성물
EP1947085A1 (fr) * 2007-01-19 2008-07-23 Laboratorios del Dr. Esteve S.A. Composé de sulfamide d'indole substituée, leur préparation et utilisation en tant que médicament
WO2008144767A1 (fr) * 2007-05-21 2008-11-27 Sgx Pharmaceuticals, Inc. Modulateurs de kinase hétérocycliques
JP2010528037A (ja) * 2007-05-24 2010-08-19 メモリー・ファーマシューティカルズ・コーポレイション ５−ｈｔ６受容体親和性を有する４’置換化合物
US20100016297A1 (en) * 2008-06-24 2010-01-21 Memory Pharmaceuticals Corporation Alkyl-substituted 3' compounds having 5-ht6 receptor affinity
US20100022581A1 (en) * 2008-07-02 2010-01-28 Memory Pharmaceuticals Corporation Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity
US20100029629A1 (en) * 2008-07-25 2010-02-04 Memory Pharmaceuticals Corporation Acyclic compounds having 5-ht6 receptor affinity
UA103195C2 (uk) 2008-08-11 2013-09-25 Глаксосмитклайн Ллк Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
US20100056531A1 (en) * 2008-08-22 2010-03-04 Memory Pharmaceuticals Corporation Alkyl-substituted 3' compounds having 5-ht6 receptor affinity
JP2012509342A (ja) * 2008-11-20 2012-04-19 オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド 置換ピロロ［２，３−ｂ］−ピリジンおよび−ピラジン
US8119683B2 (en) * 2009-08-10 2012-02-21 Taipei Medical University Aryl substituted sulfonamide compounds and their use as anticancer agents
AR081039A1 (es) 2010-05-14 2012-05-30 Osi Pharmaceuticals Llc Inhibidores biciclicos fusionados de quinasa
JP2013526570A (ja) 2010-05-14 2013-06-24 オーエスアイ・ファーマシューティカルズ，エルエルシー 縮合二環式キナーゼ阻害剤
WO2012160464A1 (fr) 2011-05-26 2012-11-29 Daiichi Sankyo Company, Limited Composés hétérocycliques en tant qu'inhibiteurs de protéine kinase
LT2734186T (lt) 2011-07-22 2018-12-10 Glaxosmithkline Llc Kompozicija
MX359671B (es) 2012-08-24 2018-10-05 Glaxosmithkline Llc Star Compuestos de pirazolopiridina.
RU2643371C2 (ru) 2012-11-20 2018-02-01 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Новые соединения
JP6228223B2 (ja) 2012-11-20 2017-11-08 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ 新規化合物
BR112015011439A2 (pt) 2012-11-20 2017-07-11 Glaxosmithkline Llc composto, composição farmacêutica, composição de vacina, e, uso de um composto
CN102977094A (zh) * 2012-11-30 2013-03-20 盛世泰科生物医药技术(苏州)有限公司 一种2-羟基-1,5-萘啶的合成方法
US9663498B2 (en) 2013-12-20 2017-05-30 Sunshine Lake Pharma Co., Ltd. Aromatic heterocyclic compounds and their application in pharmaceuticals
CN105541693B (zh) 2014-07-08 2018-10-16 广东东阳光药业有限公司 芳杂环类衍生物及其在药物上的应用
KR102378845B1 (ko) 2017-03-30 2022-03-24 엑스더블유파마 리미티드 이환형 헤테로아릴 유도체 및 이의 제조 및 용도
IL311211A (en) 2021-09-03 2024-05-01 Alexander Shulgin Res Institute Inc Asymmetric allyl tryptamines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977131A (en) 1997-04-09 1999-11-02 Pfizer Inc. Azaindole-ethylamine derivatives as nicotinic acetylcholine receptor binding agents
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
GB9820113D0 (en) * 1998-09-15 1998-11-11 Merck Sharp & Dohme Therapeutic agents
EP1173432B9 (fr) * 1999-04-21 2008-10-15 NPS Allelix Corp. Composes piperidine-indol ayant une affinite avec 5-ht6
ES2222219T3 (es) * 1999-08-12 2005-02-01 Nps Allelix Corp. Azaindoles que tienen actividad con el receptor de serotonina.
US6476034B2 (en) 2000-02-22 2002-11-05 Bristol-Myers Squibb Company Antiviral azaindole derivatives
PL210413B1 (pl) * 2001-12-20 2012-01-31 Wyeth Corp Pochodne indoliloalkiloaminy
BRPI0519036A2 (pt) * 2004-12-14 2008-12-23 Wyeth Corp mÉtodo para o tratamento de um paciente acometido por uma doenÇa neuro-degenerativa; composiÇço farmacÊutica para tratar uma doenÇa neuro-degenerativa; e uso de um agonista 5-ht6 ou de um agonista 5-ht6

Also Published As

Publication number Publication date
CA2470832A1 (fr) 2003-07-03
AR037907A1 (es) 2004-12-22
AU2002360618A1 (en) 2003-07-09
ATE396191T1 (de) 2008-06-15
US7297705B2 (en) 2007-11-20
US20050020598A1 (en) 2005-01-27
EP1456206B1 (fr) 2008-05-21
KR20040077861A (ko) 2004-09-07
EP1456206A1 (fr) 2004-09-15
RU2004122094A (ru) 2005-03-27
US7585876B2 (en) 2009-09-08
TW200301251A (en) 2003-07-01
AU2002360618B2 (en) 2009-01-08
US20030171395A1 (en) 2003-09-11
WO2003053970A1 (fr) 2003-07-03
ES2305338T3 (es) 2008-11-01
IL162242A0 (en) 2005-11-20
PL370890A1 (en) 2005-05-30
JP4339123B2 (ja) 2009-10-07
CO5590960A2 (es) 2005-12-30
JP2005519046A (ja) 2005-06-30
MXPA04005886A (es) 2004-09-13
US6800640B2 (en) 2004-10-05
DK1456206T3 (da) 2008-09-08
CA2470832C (fr) 2010-09-21
DE60226775D1 (de) 2008-07-03
CN1620455A (zh) 2005-05-25
BR0215151A (pt) 2004-10-19
ZA200405733B (en) 2005-10-19
US20080114023A1 (en) 2008-05-15

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Legal Events

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