NO20043790L - Formuleringer med atorvastatin stabilisert med alkalimetalltilsetninger - Google Patents
Formuleringer med atorvastatin stabilisert med alkalimetalltilsetningerInfo
- Publication number
- NO20043790L NO20043790L NO20043790A NO20043790A NO20043790L NO 20043790 L NO20043790 L NO 20043790L NO 20043790 A NO20043790 A NO 20043790A NO 20043790 A NO20043790 A NO 20043790A NO 20043790 L NO20043790 L NO 20043790L
- Authority
- NO
- Norway
- Prior art keywords
- atorvastatin
- formulations
- stabilized
- alkali metal
- metal additives
- Prior art date
Links
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 title 1
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 title 1
- 239000000654 additive Substances 0.000 title 1
- 229910052783 alkali metal Inorganic materials 0.000 title 1
- 150000001340 alkali metals Chemical class 0.000 title 1
- 229960005370 atorvastatin Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Obesity (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN112DE2002 | 2002-02-14 | ||
| PCT/IB2003/000505 WO2003068191A1 (fr) | 2002-02-14 | 2003-02-14 | Formulations d'atorvastatine stabilisee avec des adjonctions de metaux alcalins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20043790L true NO20043790L (no) | 2004-11-08 |
Family
ID=27620520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20043790A NO20043790L (no) | 2002-02-14 | 2004-09-09 | Formuleringer med atorvastatin stabilisert med alkalimetalltilsetninger |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20030175338A1 (fr) |
| EP (1) | EP1336405A1 (fr) |
| JP (1) | JP2005522444A (fr) |
| KR (1) | KR20040101229A (fr) |
| CN (1) | CN1642526A (fr) |
| AP (1) | AP2004003112A0 (fr) |
| AR (1) | AR038839A1 (fr) |
| AU (1) | AU2003245736A1 (fr) |
| BR (1) | BR0307720A (fr) |
| CA (1) | CA2475722A1 (fr) |
| CO (1) | CO5600997A2 (fr) |
| EA (1) | EA200401059A1 (fr) |
| EC (1) | ECSP045235A (fr) |
| HR (1) | HRP20040829A2 (fr) |
| IL (1) | IL163550A0 (fr) |
| IS (1) | IS7404A (fr) |
| MX (1) | MXPA04007905A (fr) |
| NO (1) | NO20043790L (fr) |
| OA (1) | OA12777A (fr) |
| PE (1) | PE20030935A1 (fr) |
| PL (1) | PL371337A1 (fr) |
| WO (1) | WO2003068191A1 (fr) |
| ZA (1) | ZA200406970B (fr) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002057229A1 (fr) | 2001-01-19 | 2002-07-25 | Biocon India Limited | FORME V CRISTALLINE DE SEL HEMICALCIQUE D'ACIDE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIQUE (ATORVASTATINE) |
| US7361772B2 (en) * | 2001-08-16 | 2008-04-22 | Biocon Limited | Process for the production of atorvastatin calcium |
| BR0215644A (pt) | 2002-03-18 | 2004-12-21 | Biocon Ltd | Inibidores de redutase de hmg-coa amorfos do tamanho de partìcula desejado |
| US7179942B2 (en) | 2002-07-05 | 2007-02-20 | Bicon Limited | Halo-substituted active methylene compounds |
| WO2004094343A1 (fr) | 2003-04-22 | 2004-11-04 | Biocon Limited | Nouveau procede pour une reduction stereoselective de $g(b)-setoesters |
| US7790197B2 (en) | 2003-06-09 | 2010-09-07 | Warner-Lambert Company Llc | Pharmaceutical compositions of atorvastatin |
| US20050271717A1 (en) * | 2003-06-12 | 2005-12-08 | Alfred Berchielli | Pharmaceutical compositions of atorvastatin |
| EP1653930B1 (fr) * | 2003-08-05 | 2007-12-19 | Zentiva, a.s. | Procedes de stabilisation de l'atorvastatine |
| US7557238B2 (en) | 2003-09-18 | 2009-07-07 | Biocon Limited | Process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate |
| EP1689368B1 (fr) | 2003-12-04 | 2016-09-28 | Bend Research, Inc | Procédé d'atomisation/congélation faisant appel à une extrudeuse pour la préparation de compositions médicamenteuses cristallines multiparticulaires |
| DE102004008074A1 (de) | 2004-02-19 | 2005-09-15 | Heidelberger Druckmaschinen Ag | Verfahren und Testform zum Abgleichen der Belichtungsköpfe in einem Belichter für Druckvorlagen |
| US20090042979A1 (en) * | 2004-08-06 | 2009-02-12 | Transform Pharmaceuticals Inc. | Novel Statin Pharmaceutical Compositions and Related Methods of Treatment |
| AU2005271413A1 (en) * | 2004-08-06 | 2006-02-16 | Transform Pharmaceuticals, Inc. | Novel statin pharmaceutical compositions and related methods of treatment |
| KR20070052760A (ko) * | 2004-08-06 | 2007-05-22 | 트렌스폼 파마수티컬스 인코퍼레이티드 | 신규한 페노피브레이트 제제 및 관련된 치료방법 |
| JP2008514722A (ja) * | 2004-09-30 | 2008-05-08 | ドクター レディズ ラボラトリーズ リミテッド | 非結晶性アトルバスタチンカルシウム |
| KR20070067175A (ko) * | 2004-10-28 | 2007-06-27 | 워너-램버트 캄파니 엘엘씨 | 무정형 아토르바스타틴 형성 방법 |
| CA2588216A1 (fr) * | 2004-11-22 | 2006-05-26 | Dexcel Pharma Technologies Ltd. | Formulations d'atorvastatine stables |
| JP2008521878A (ja) * | 2004-12-02 | 2008-06-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 非晶質アトルバスタチンの医薬組成物及びその製造のための方法 |
| ES2263370B1 (es) * | 2005-02-16 | 2007-12-01 | Ercros Industrial, S.A. | Atorvastatina calcica amorfa estabilizada y procedimiento para su obtencion. |
| WO2006123358A2 (fr) * | 2005-02-22 | 2006-11-23 | Sun Pharmaceutical Industries Limited | Composition pharmaceutique orale stable |
| WO2006117761A2 (fr) * | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Sels de magnesium d'inhibiteurs de hmg-coa reductase |
| US20070004671A1 (en) * | 2005-05-20 | 2007-01-04 | Agarwal Sudeep K | Stable desloratadine compositions |
| EP1898922A4 (fr) * | 2005-07-04 | 2012-03-14 | Ramu Krishnan | Medicament ou composes pharmaceutiques ameliores et preparation associee |
| JP2009515816A (ja) * | 2005-08-04 | 2009-04-16 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | フェノフィブレートおよびスタチンを含んでなる新規調合物、ならびに関連する処置方法 |
| CA2628716C (fr) | 2005-11-10 | 2016-09-27 | Alphapharm Pty Ltd | Processus de regulation de la dimension de particule |
| AU2006313009B2 (en) * | 2005-11-10 | 2013-10-24 | Alphapharm Pty Ltd | Process to control particle size |
| DE602006014193D1 (de) | 2005-11-21 | 2010-06-17 | Warner Lambert Co | Neue formen von är-(r*,r*)ü-2-(4-fluorphenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-ä(phenylamino)carbonylü-1h-pyrrol-1-heptansäure-magnesium |
| EP1954653A4 (fr) * | 2005-11-23 | 2010-11-03 | Merck Sharp & Dohme | Procede de generation de solide amorphe pour agents pharmaceutiques insolubles dans l'eau |
| JP2009517459A (ja) * | 2005-11-29 | 2009-04-30 | バイオコン・リミテッド | ［Ｒ−（Ｒ＊，Ｒ＊）］−２−（４−フルオロフェニル）−β，δ−ジヒドロキシ−５−（１−メチルエチル）−３−フェニル−４−［（フェニルアミノ）カルボニル］−１Ｈ−ピロール−１−ヘプタン酸マグネシウム塩（２：１）の多形 |
| EP1810667A1 (fr) * | 2006-01-20 | 2007-07-25 | KRKA, tovarna zdravil, d.d., Novo mesto | Composition pharmaceutique contenant de l'atorvastatin amorphé |
| EP1905424A3 (fr) * | 2006-02-02 | 2008-04-30 | Ranbaxy Laboratories Limited | Procédé de preparation d'une composition pharmaceutique comprenant des particules de statine stabilisées |
| EP1818049A3 (fr) * | 2006-02-10 | 2008-11-19 | LifeCycle Pharma A/S | Atorvastatin stabilisée |
| WO2007099552A2 (fr) * | 2006-03-02 | 2007-09-07 | Matrix Labaratories Ltd | Nouvelle forme cristalline d'atorvastatine hémi-magnésium |
| HU227696B1 (en) * | 2006-04-13 | 2011-12-28 | Egyt Gyogyszervegyeszeti Gyar | Zinc salt of rosuvastatin, process for its preparation and pharmaceutical compositions containing it |
| SI22255A (sl) * | 2006-04-14 | 2007-10-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Novi polimorfi statinovih soli in njihova uporabav farmacevtskih formulacijah |
| WO2007132472A1 (fr) * | 2006-05-11 | 2007-11-22 | Biocon Limited | Forme cristalline b4 d'atorvastatine-magnésium et procédé correspondant |
| US20080038332A1 (en) * | 2006-08-10 | 2008-02-14 | Cai Gu Huang | Stable pharmaceutical formulation comprising atorvastatin calcium |
| HU227610B1 (en) * | 2006-09-18 | 2011-09-28 | Richter Gedeon Nyrt | Pharmaceutical compositions containing rosuvastatin potassium |
| AU2007300071A1 (en) * | 2006-09-27 | 2008-04-03 | Dr. Reddy's Laboratories Ltd. | Atorvastatin pharmaceutical compositions |
| JP2010513324A (ja) * | 2006-12-21 | 2010-04-30 | アルファファーム ピーティーワイ リミテッド | 医薬化合物および医薬組成物 |
| IS8587A (is) * | 2006-12-27 | 2008-06-28 | Actavis Group Hf. | Atorvastatin lyfjasamsetning |
| CN101224205B (zh) * | 2007-01-20 | 2010-11-17 | 石药集团中奇制药技术（石家庄）有限公司 | 一种阿托伐他汀和左旋氨氯地平的组合物及其制备方法 |
| IS8607A (is) * | 2007-02-09 | 2008-08-10 | Actavis Group Hf. | Stöðugar atorvastatin samsetningar |
| CZ300047B6 (cs) * | 2007-03-02 | 2009-01-21 | Zentiva, A. S. | Farmaceutická kompozice s obsahem úcinné látky atorvastatinu |
| US20100152274A1 (en) * | 2007-04-13 | 2010-06-17 | Nicox S.A. | Crystalline forms of atorvastatin 4-(nitrooxy) butyl ester |
| WO2009013633A2 (fr) * | 2007-07-20 | 2009-01-29 | Actavis Group Ptc Ehf | Coprécipités amorphes de sels pharmaceutiquement acceptables d'atorvastatine |
| WO2009024889A2 (fr) | 2007-08-21 | 2009-02-26 | Ranbaxy Laboratories Limited | Composition pharmaceutique comprenant un inhibiteur de réductase hmg-coa et un ézétimibe |
| US20110064816A1 (en) * | 2008-05-13 | 2011-03-17 | Dr. Reddy's Laboratories Ltd. | Atorvastatin compositions |
| US20110082071A1 (en) * | 2008-05-15 | 2011-04-07 | Amal Elabbadi | Delivery system for an active ingredient |
| EP2127628A1 (fr) | 2008-05-27 | 2009-12-02 | Ranbaxy Laboratories Limited | Emballage de dose d'unité |
| EP2318350A4 (fr) * | 2008-07-25 | 2012-11-28 | Alphapharm Pty Ltd | ATOVAQUONE À DIAMÈTRE DE PARTICULES (D90) VARIANT DE PLUS DE 3 muM À ENVIRON 10 muM |
| EP2341773A4 (fr) * | 2008-09-24 | 2012-03-07 | Merck Sharp & Dohme | Compositions pharmaceutiques d atorvastatine |
| WO2010038688A1 (fr) * | 2008-09-30 | 2010-04-08 | アステラス製薬株式会社 | Composition pharmaceutique particulaire pour une administration orale d’atorvastatine |
| CN101791297B (zh) * | 2010-02-10 | 2012-03-28 | 中国药科大学 | 阿托伐他汀钙口崩片及其制备方法 |
| JP5614445B2 (ja) * | 2010-03-29 | 2014-10-29 | アステラス製薬株式会社 | 経口投与用粒子状医薬組成物 |
| JP5534004B2 (ja) * | 2010-03-29 | 2014-06-25 | アステラス製薬株式会社 | 口腔内崩壊錠 |
| US8372877B2 (en) * | 2010-04-16 | 2013-02-12 | Cumberland Pharmaceuticals | Stabilized statin formulations |
| EP2566465A2 (fr) * | 2010-05-04 | 2013-03-13 | Mahmut Bilgic | Formulations stables de rosuvastatine |
| HUP1000299A2 (hu) | 2010-06-08 | 2012-02-28 | Nanoform Cardiovascular Therapeutics Ltd | Nanostrukturált Atorvastatint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás elõállításukra |
| WO2011154009A1 (fr) * | 2010-06-10 | 2011-12-15 | Lifecycle Pharma A/S | Composition comprenant un principe actif sous une forme amorphe et une substance poreuse adsorbante |
| US20120165386A1 (en) * | 2010-12-27 | 2012-06-28 | Ranbaxy Laboratories Limited | Stable oral pharmaceutial composition of atorvastatin |
| WO2013072770A2 (fr) | 2011-11-15 | 2013-05-23 | Dr. Reddy's Laboratories Ltd. | Formulations pharmaceutiques comprenant de l'atorvastatine et du glimépiride |
| CN104069502B (zh) * | 2013-03-29 | 2018-02-16 | 北京罗诺强施医药技术研发中心有限公司 | 复合骨架材料及其药物组合物 |
| JP6507808B2 (ja) * | 2015-04-09 | 2019-05-08 | ニプロ株式会社 | 口腔内崩壊錠 |
| WO2017106130A1 (fr) * | 2015-12-16 | 2017-06-22 | Merck Sharp & Dohme Corp. | Procédé de préparation de compositions pharmaceutiques |
| EP3184103A1 (fr) | 2015-12-21 | 2017-06-28 | Hexal AG | Composition pharmaceutique comprenant de l'atorvastatine ou un sel de celui-ci |
| CN106420645A (zh) * | 2016-11-24 | 2017-02-22 | 浙江新东港药业股份有限公司 | 一种含阿托伐他汀钙片及制备方法 |
| CN108421045B (zh) * | 2018-04-02 | 2021-09-24 | 北京海晶生物医药科技有限公司 | 一种阿托伐他汀钙组合物、制剂及其制备方法 |
| CN109044989A (zh) * | 2018-10-09 | 2018-12-21 | 河南师范大学 | 一种阿托伐他汀钙胶囊制剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU9203780D0 (en) * | 1991-12-12 | 1993-03-29 | Sandoz Ag | Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them |
| SG45369A1 (en) * | 1993-01-19 | 1998-10-16 | Warner Lambert Co | Stable oral ci-981 formulation and process of preparing same |
| SI20109A (sl) * | 1998-12-16 | 2000-06-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Stabilna farmacevtska formulacija |
| US6242003B1 (en) * | 2000-04-13 | 2001-06-05 | Novartis Ag | Organic compounds |
| SI20848A (sl) * | 2001-03-14 | 2002-10-31 | Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D. | Farmacevtska formulacija, ki vsebuje atorvastatin kalcij |
-
2003
- 2003-02-14 AU AU2003245736A patent/AU2003245736A1/en not_active Abandoned
- 2003-02-14 CA CA002475722A patent/CA2475722A1/fr not_active Abandoned
- 2003-02-14 CN CNA038070286A patent/CN1642526A/zh active Pending
- 2003-02-14 KR KR10-2004-7012657A patent/KR20040101229A/ko not_active Withdrawn
- 2003-02-14 OA OA1200400219A patent/OA12777A/en unknown
- 2003-02-14 WO PCT/IB2003/000505 patent/WO2003068191A1/fr not_active Ceased
- 2003-02-14 AP APAP/P/2004/003112A patent/AP2004003112A0/en unknown
- 2003-02-14 IL IL16355003A patent/IL163550A0/xx unknown
- 2003-02-14 HR HR20040829A patent/HRP20040829A2/xx not_active Application Discontinuation
- 2003-02-14 JP JP2003567375A patent/JP2005522444A/ja active Pending
- 2003-02-14 EP EP03405088A patent/EP1336405A1/fr not_active Withdrawn
- 2003-02-14 US US10/367,552 patent/US20030175338A1/en not_active Abandoned
- 2003-02-14 BR BR0307720-9A patent/BR0307720A/pt not_active IP Right Cessation
- 2003-02-14 PE PE2003000161A patent/PE20030935A1/es not_active Application Discontinuation
- 2003-02-14 AR ARP030100494A patent/AR038839A1/es not_active Application Discontinuation
- 2003-02-14 EA EA200401059A patent/EA200401059A1/ru unknown
- 2003-02-14 PL PL03371337A patent/PL371337A1/xx not_active Application Discontinuation
- 2003-02-14 MX MXPA04007905A patent/MXPA04007905A/es not_active Application Discontinuation
-
2004
- 2004-08-13 CO CO04079402A patent/CO5600997A2/es not_active Application Discontinuation
- 2004-08-13 IS IS7404A patent/IS7404A/is unknown
- 2004-08-16 EC EC2004005235A patent/ECSP045235A/es unknown
- 2004-09-01 ZA ZA200406970A patent/ZA200406970B/en unknown
- 2004-09-09 NO NO20043790A patent/NO20043790L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200406970B (en) | 2005-06-20 |
| CN1642526A (zh) | 2005-07-20 |
| OA12777A (en) | 2006-07-06 |
| AU2003245736A1 (en) | 2003-09-04 |
| CO5600997A2 (es) | 2006-01-31 |
| PL371337A1 (en) | 2005-06-13 |
| AR038839A1 (es) | 2005-01-26 |
| EP1336405A1 (fr) | 2003-08-20 |
| MXPA04007905A (es) | 2004-11-26 |
| IL163550A0 (en) | 2005-12-18 |
| CA2475722A1 (fr) | 2003-08-21 |
| IS7404A (is) | 2004-08-13 |
| BR0307720A (pt) | 2005-01-25 |
| HRP20040829A2 (en) | 2006-07-31 |
| JP2005522444A (ja) | 2005-07-28 |
| PE20030935A1 (es) | 2003-10-30 |
| KR20040101229A (ko) | 2004-12-02 |
| US20030175338A1 (en) | 2003-09-18 |
| EA200401059A1 (ru) | 2005-02-24 |
| WO2003068191A1 (fr) | 2003-08-21 |
| AP2004003112A0 (en) | 2004-09-30 |
| ECSP045235A (es) | 2004-09-28 |
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