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NO20042266L - Kombinasjoner av antistoffer selektive for en tumor nekrose faktor-relatert apoptose-induserende ligandreseptor og andre terapeutiske midler - Google Patents

Kombinasjoner av antistoffer selektive for en tumor nekrose faktor-relatert apoptose-induserende ligandreseptor og andre terapeutiske midler

Info

Publication number
NO20042266L
NO20042266L NO20042266A NO20042266A NO20042266L NO 20042266 L NO20042266 L NO 20042266L NO 20042266 A NO20042266 A NO 20042266A NO 20042266 A NO20042266 A NO 20042266A NO 20042266 L NO20042266 L NO 20042266L
Authority
NO
Norway
Prior art keywords
therapeutic agents
combinations
necrosis factor
tumor necrosis
ligand receptor
Prior art date
Application number
NO20042266A
Other languages
English (en)
Other versions
NO333828B1 (no
Inventor
Tong Zhou
Robert P Kimberly
William J Koopman
Albert F Lobuglio
Donald J Buchsbaum
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of NO20042266L publication Critical patent/NO20042266L/no
Publication of NO333828B1 publication Critical patent/NO333828B1/no

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
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    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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NO20042266A 2001-11-01 2004-06-01 In-vitro metode for selektivt å indusere apoptose i målceller som uttrykker DR5 og sammensetning NO333828B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34640201P 2001-11-01 2001-11-01
US39147802P 2002-06-24 2002-06-24
PCT/US2002/034420 WO2003038043A2 (en) 2001-11-01 2002-10-25 Combinations of dr5 antibody and other therapeutic agents

Publications (2)

Publication Number Publication Date
NO20042266L true NO20042266L (no) 2004-07-23
NO333828B1 NO333828B1 (no) 2013-09-23

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ID=26994839

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042266A NO333828B1 (no) 2001-11-01 2004-06-01 In-vitro metode for selektivt å indusere apoptose i målceller som uttrykker DR5 og sammensetning

Country Status (20)

Country Link
EP (1) EP1506285B1 (no)
JP (1) JP4663232B2 (no)
KR (1) KR20040081422A (no)
CN (1) CN100506277C (no)
AT (1) ATE491019T1 (no)
AU (1) AU2002360307B2 (no)
BR (1) BRPI0213846B8 (no)
CA (1) CA2465314C (no)
CO (1) CO5650175A2 (no)
DE (1) DE60238560D1 (no)
HU (1) HU230378B1 (no)
IL (2) IL161686A0 (no)
MX (1) MXPA04004184A (no)
NO (1) NO333828B1 (no)
NZ (2) NZ533164A (no)
PL (1) PL216750B1 (no)
RO (1) RO123525B1 (no)
RU (1) RU2313368C2 (no)
WO (1) WO2003038043A2 (no)
ZA (1) ZA200403573B (no)

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US8071740B2 (en) * 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
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US7361341B2 (en) 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US7348003B2 (en) 2001-05-25 2008-03-25 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
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CA2463816C (en) 2001-10-19 2014-07-08 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
AU2008201431B2 (en) * 2002-11-27 2011-11-24 Irm, Llc Methods and compositions for inducing Apoptosis in cancer cells
DE60334247D1 (de) * 2002-11-27 2010-10-28 Irm Llc Verfahren und zusammensetzungen zur apoptoseinduktion in krebszellen
US20060228331A1 (en) 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
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KR20070010046A (ko) * 2004-04-06 2007-01-19 제넨테크, 인크. Dr5 항체 및 그의 용도
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BRPI0513639A (pt) 2004-08-06 2008-05-13 Genentech Inc métodos de previsão da sensibilidade, métodos de indução da apoptose e métodos de tratamento de disfunção em mamìferos e de cáncer
NZ553174A (en) * 2004-09-08 2010-03-26 Genentech Inc Methods of using death receptor ligands Apo2L/Trail and CD20 antibodies
JP2008512479A (ja) * 2004-09-08 2008-04-24 ジェネンテック・インコーポレーテッド デスレセプターリガンド及びcd20抗体の使用方法
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US8029783B2 (en) 2005-02-02 2011-10-04 Genentech, Inc. DR5 antibodies and articles of manufacture containing same
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