NO20042697L - Fremgangsmater for behandling av kreft ved anvendelse av en kombinasjon av en tumoravledet dendrittcelleinhiberende faktor-antagonist og en Toll-lignende reseptorantagonist - Google Patents
Fremgangsmater for behandling av kreft ved anvendelse av en kombinasjon av en tumoravledet dendrittcelleinhiberende faktor-antagonist og en Toll-lignende reseptorantagonistInfo
- Publication number
- NO20042697L NO20042697L NO20042697A NO20042697A NO20042697L NO 20042697 L NO20042697 L NO 20042697L NO 20042697 A NO20042697 A NO 20042697A NO 20042697 A NO20042697 A NO 20042697A NO 20042697 L NO20042697 L NO 20042697L
- Authority
- NO
- Norway
- Prior art keywords
- antagonist
- toll
- tumor
- methods
- combination
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 2
- 102000002689 Toll-like receptor Human genes 0.000 title 1
- 108020000411 Toll-like receptor Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 210000004443 dendritic cell Anatomy 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33343401P | 2001-11-27 | 2001-11-27 | |
| PCT/US2002/038098 WO2003045431A2 (en) | 2001-11-27 | 2002-11-26 | Methods for treating cancer using a combination of a tumor-derived dendritic cell inhibitory factor antagonist and a toll-like receptor agonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20042697L true NO20042697L (no) | 2004-06-25 |
Family
ID=23302758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20042697A NO20042697L (no) | 2001-11-27 | 2004-06-25 | Fremgangsmater for behandling av kreft ved anvendelse av en kombinasjon av en tumoravledet dendrittcelleinhiberende faktor-antagonist og en Toll-lignende reseptorantagonist |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20030138413A1 (no) |
| EP (1) | EP1450858A2 (no) |
| JP (3) | JP2006502080A (no) |
| CN (1) | CN1617742B (no) |
| AU (1) | AU2002359516B2 (no) |
| BR (1) | BR0214457A (no) |
| CA (1) | CA2468320A1 (no) |
| HU (1) | HUP0500999A2 (no) |
| MX (1) | MXPA04004998A (no) |
| NO (1) | NO20042697L (no) |
| NZ (1) | NZ565420A (no) |
| TW (1) | TW200303759A (no) |
| WO (1) | WO2003045431A2 (no) |
| ZA (1) | ZA200404113B (no) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| NZ508927A (en) | 1998-05-22 | 2003-12-19 | Ottawa Health Research Inst | Methods and products for inducing mucosal immunity |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| EP1322655B1 (en) | 2000-01-14 | 2007-11-14 | The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| EP1311288A1 (en) * | 2000-01-20 | 2003-05-21 | Ottawa Health Research Institute | Immunostimulatory nucleic acids for inducing a th2 immune response |
| US20040175355A1 (en) * | 2001-04-18 | 2004-09-09 | The Regents Of The University Of California | Methods of using secondary lymphoid organ chemokine to modulate physiological processes in mammals |
| US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
| WO2003020884A2 (en) * | 2001-08-14 | 2003-03-13 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| EP2196217A1 (en) | 2001-09-14 | 2010-06-16 | Cytos Biotechnology AG | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
| US7615227B2 (en) * | 2001-12-20 | 2009-11-10 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce angiogenesis |
| US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
| US8263091B2 (en) * | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
| WO2004053104A2 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5’ cpg nucleic acids and methods of use |
| EP2572715A1 (en) * | 2002-12-30 | 2013-03-27 | 3M Innovative Properties Company | Immunostimulatory Combinations |
| JP2006517970A (ja) * | 2003-02-14 | 2006-08-03 | ユニバーシティ オブ サザン カリフォルニア | 癌免疫療法のための組成物及び方法 |
| US7537767B2 (en) | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| NZ542323A (en) | 2003-03-26 | 2008-07-31 | Cytos Biotechnology Ag | Melan-A peptide analogue-virus-like-particle conjugates |
| CA2544240A1 (en) * | 2003-07-22 | 2005-02-17 | Cytos Biotechnology Ag | Cpg-packaged liposomes |
| HUE039803T2 (hu) * | 2004-01-07 | 2019-02-28 | Novartis Vaccines & Diagnostics Inc | M-CSF-specifikus monoklonális ellenanyag és alkalmazásai |
| US20050256073A1 (en) * | 2004-02-19 | 2005-11-17 | Coley Pharmaceutical Group, Inc. | Immunostimulatory viral RNA oligonucleotides |
| AU2005330703A1 (en) * | 2004-07-19 | 2006-10-26 | Baylor College Of Medicine | Modulation of cytokine signaling regulators and applications for immunotherapy |
| CA2574176A1 (en) * | 2004-07-20 | 2006-02-09 | Schering Corporation | Induction of apoptosis in toll-like receptor expressing tumor cells |
| US20080274140A1 (en) | 2004-11-19 | 2008-11-06 | David B Weiner | Vaccines and Methods for Using the Same |
| EP1834650A1 (en) * | 2004-12-28 | 2007-09-19 | ImmunoFrontier, Inc. | Cancer vaccine preparation |
| EP1712241A1 (en) | 2005-04-15 | 2006-10-18 | Centre National De La Recherche Scientifique (Cnrs) | Composition for treating cancer adapted for intra-tumoral administration and uses thereof |
| US20100143899A1 (en) * | 2005-05-17 | 2010-06-10 | University Of Vermont And State Agricultural College | Methods and products for diagnosing cancer |
| US7868159B2 (en) * | 2005-06-23 | 2011-01-11 | Baylor College Of Medicine | Modulation of negative immune regulators and applications for immunotherapy |
| MX2008000596A (es) * | 2005-07-11 | 2008-03-19 | Cbio Ltd | Inmunomodulacion inducida por la chaperonina 10. |
| AU2006321287B2 (en) * | 2005-12-01 | 2013-05-09 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | Compositions and methods relating to treatment of cancer and infectious diseases |
| JP5484732B2 (ja) | 2005-12-14 | 2014-05-07 | サイトス バイオテクノロジー アーゲー | 過敏症の治療のための免疫賦活性核酸パッケージ粒子 |
| PT2032592E (pt) | 2006-06-12 | 2013-08-28 | Cytos Biotechnology Ag | Processos para o empacotamento de oligonucleótidos em partículas semelhantes a vírus de bacteriófagos de arn |
| DE102006035618A1 (de) * | 2006-07-31 | 2008-02-07 | Curevac Gmbh | Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz |
| US20080124366A1 (en) * | 2006-08-06 | 2008-05-29 | Ohlfest John R | Methods and Compositions for Treating Tumors |
| US20090074711A1 (en) * | 2006-09-07 | 2009-03-19 | University Of Southhampton | Human therapies using chimeric agonistic anti-human cd40 antibody |
| EP2079305A4 (en) * | 2006-12-12 | 2010-01-27 | Idera Pharmaceuticals Inc | SYNTHETIC AGONISTS OF TLR9 |
| WO2008134020A1 (en) * | 2007-04-26 | 2008-11-06 | University Of Vermont And State Agricultural College | Ccl18 and ccl3 methods and compositions for detecting and treating cancer |
| US8324369B2 (en) * | 2007-11-30 | 2012-12-04 | Baylor College Of Medicine | Dendritic cell vaccine compositions and uses of same |
| EP2391718A2 (en) * | 2009-01-30 | 2011-12-07 | Idera Pharmaceuticals, Inc. | Novel synthetic agonists of tlr9 |
| EP2509627B1 (en) | 2009-12-07 | 2017-01-25 | The Board of Trustees of The Leland Stanford Junior University | Methods for enhancing anti-tumor antibody therapy |
| US20120309691A1 (en) * | 2010-02-04 | 2012-12-06 | Dapeng Zhou | Tumor targeted delivery of immunomodulators by nanopolymers |
| ES2769326T3 (es) * | 2010-02-05 | 2020-06-25 | Univ Cornell | Métodos y composiciones para la inmunoterapia contra el cáncer usando células tumorales que expresan la proteína de fusión de flagelina y antígeno asociado al tumor |
| AU2011281192A1 (en) | 2010-07-19 | 2013-02-28 | Yeda Research And Development Co. Ltd. | Peptides based on the transmembrane domain of a Toll-like receptor (TLR) for treatment of TLR-mediated diseases |
| CA2807585A1 (en) * | 2010-08-13 | 2012-02-16 | Baylor Research Institute | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells |
| SG10201610251PA (en) * | 2012-06-08 | 2017-01-27 | Aduro Biotech | Compositions and methods for cancer immunotherapy |
| EP3033417B1 (en) * | 2012-06-27 | 2019-12-25 | Kenichiro Hasumi | Therapy and method for intratumorally introducing cytotoxic t lymphocyte and/or nkt cell with anti-tnf and/or anti-il-10 |
| WO2014038641A1 (ja) | 2012-09-05 | 2014-03-13 | 中外製薬株式会社 | アミノ酸およびステリル基が導入されたヒアルロン酸誘導体 |
| CN103768604B (zh) * | 2012-10-24 | 2016-03-30 | 北京圣沃德生物科技有限公司 | 治疗性肿瘤疫苗 |
| EA201590396A1 (ru) | 2012-12-13 | 2015-12-30 | Адуро Биотек, Инк. | Композиция, содержащая циклические пуриновые динуклеотиды с определенной стереохимией, и способ ее получения и применения |
| CN103013915B (zh) * | 2013-01-09 | 2014-05-28 | 高岱清 | 一种高活性负载抗原的树突状细胞的制备方法 |
| AU2014260015B2 (en) | 2013-04-29 | 2019-11-14 | Memorial Sloan Kettering Cancer Center | Compositions and methods for altering second messenger signaling |
| CN105377867B (zh) | 2013-05-03 | 2019-11-12 | 加利福尼亚大学董事会 | I型干扰素的环状二核苷酸诱导 |
| US9724408B2 (en) | 2013-05-18 | 2017-08-08 | Aduro Biotech, Inc. | Compositions and methods for activating stimulator of interferon gene-dependent signalling |
| US9549944B2 (en) | 2013-05-18 | 2017-01-24 | Aduro Biotech, Inc. | Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling |
| CA2919268C (en) | 2013-07-25 | 2023-09-05 | Exicure, Inc. | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
| EP3027227A4 (en) | 2013-07-31 | 2018-05-23 | Memorial Sloan Kettering Cancer Center | Sting crystals and modulators |
| WO2015187966A1 (en) | 2014-06-04 | 2015-12-10 | Aurasense Therapeutics, Llc | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗mfi2抗體及使用方法 |
| CN107106493A (zh) | 2014-11-21 | 2017-08-29 | 西北大学 | 球形核酸纳米颗粒缀合物的序列特异性细胞摄取 |
| SG10201907164SA (en) | 2015-04-22 | 2019-09-27 | Curevac Ag | Rna containing composition for treatment of tumor diseases |
| EP3291821A4 (en) * | 2015-05-07 | 2019-03-20 | Baylor College of Medicine | IMMUNOTHERAPY WITH DENDRITIC CELLS |
| BR112017023849A2 (pt) | 2015-05-07 | 2018-07-17 | Agenus Inc. | anticorpos anti-ox40 e métodos de uso dos mesmos |
| CA2986232A1 (en) * | 2015-05-29 | 2016-12-08 | Merck Sharp & Dohme Corp. | Combination of an anti-il-10 antibody and a cpg-c type oligonucleotide for treating cancer |
| RU2017145940A (ru) * | 2015-05-29 | 2019-07-02 | Дайнэвокс Текнолоджиз Корпорейшн | Внутрилегочное введение полинуклеотидных агонистов толл-подобного рецептора 9 для лечения рака легких |
| TW201716084A (zh) * | 2015-08-06 | 2017-05-16 | 葛蘭素史克智慧財產發展有限公司 | 組合物及其用途與治療 |
| AU2016304597B2 (en) * | 2015-08-06 | 2022-10-06 | Memorial Sloan Kettering Cancer Center | Methods and compositions for tumor therapy |
| MA44334A (fr) | 2015-10-29 | 2018-09-05 | Novartis Ag | Conjugués d'anticorps comprenant un agoniste du récepteur de type toll |
| MX2018006477A (es) | 2015-12-02 | 2018-09-03 | Agenus Inc | Anticuerpos y metodos de uso de estos. |
| WO2017192470A1 (en) * | 2016-05-03 | 2017-11-09 | Merck Sharp & Dohme Corp. | Combination therapy of anti-il-10 antibody and compositions comprising lipid nanoparticles and tlr9 agonist cpg oligonucleotides |
| US20190125804A1 (en) * | 2016-06-15 | 2019-05-02 | Tissue Regeneration Therapeutics Inc. | Anti-cancer use of genetically modified human umbilical cord perivascular cells (hucpvc) |
| US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
| WO2018060514A1 (en) | 2016-09-30 | 2018-04-05 | Galderma Research & Development | Methods and compositions combining at least one pattern recognition receptor (prr) agonist with an anti-il10 receptor antibody |
| WO2018060513A1 (en) | 2016-09-30 | 2018-04-05 | Galderma Research & Development | Methods and compositions for treating precancerous lesions or cancer comprising tlr/tlr or tlr/clr agonists |
| EP3538152A4 (en) | 2016-11-09 | 2020-09-30 | Agenus Inc. | ANTI-OX40 ANTIBODIES, ANTI-GITR ANTIBODIES, AND PROCESSES FOR USE |
| AU2018222737B2 (en) * | 2017-02-17 | 2021-03-25 | Aivita Biomedical, Inc. | Methods to enhance tumor immunogenicity and compositions for autologous cancer immunotherapeutic products using modified tumor cells and modified dendritic cells |
| JP7348074B2 (ja) * | 2017-06-04 | 2023-09-20 | ラパポート・ファミリー・インスティテュート・フォー・リサーチ・イン・ザ・メディカル・サイエンシーズ | がん治療に対する個別化応答の予測方法およびそのキット |
| EP3810641A4 (en) * | 2018-06-19 | 2022-07-13 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | ONCOLYTIC VIRUS OR ANTIGEN PRESENT CELL MEDIATED CANCER THERAPY USING TYPE I INTERFERON AND CD40 LIGAND |
| CN113005090A (zh) * | 2019-12-20 | 2021-06-22 | 上海细胞治疗集团有限公司 | 共表达趋化因子和共刺激分子的dc细胞及其应用 |
| WO2021168274A1 (en) | 2020-02-21 | 2021-08-26 | Silverback Therapeutics, Inc. | Nectin-4 antibody conjugates and uses thereof |
| WO2021252904A1 (en) * | 2020-06-11 | 2021-12-16 | Massachusetts Institute Of Technology | Ribonucleoprotein approach to boost the sting signaling for cancer immunotherapy |
| CN116209678A (zh) | 2020-07-01 | 2023-06-02 | 安尔士制药公司 | 抗asgr1抗体缀合物及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987006830A1 (en) * | 1986-05-09 | 1987-11-19 | Sloan-Kettering Institute For Cancer Research | Lipopolysaccharide and natural factor compositions for anti-tumor therapy and method of treatment |
| US5840708A (en) * | 1992-12-14 | 1998-11-24 | Allegheny University Of The Health Sciences | Administration of oligonucleotides antisense to dopamine receptor MRNA for diagnosis and treatment of Neurological pathologies |
| AUPM322393A0 (en) * | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| ES2366201T3 (es) * | 1994-07-15 | 2011-10-18 | University Of Iowa Research Foundation | Oligonucleótidos inmunmoduladores. |
| US6071535A (en) * | 1996-01-31 | 2000-06-06 | Collaborative Laboratories, Inc. | Lipid vesicles formed with alkylammonium fatty acid salts |
| EP0930893B1 (en) * | 1996-10-11 | 2005-04-13 | The Regents of The University of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| US7390619B1 (en) * | 1998-02-11 | 2008-06-24 | Maxygen, Inc. | Optimization of immunomodulatory properties of genetic vaccines |
| CA2323929C (en) * | 1998-04-03 | 2004-03-09 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| AU764969B2 (en) * | 1999-04-19 | 2003-09-04 | Smithkline Beecham Biologicals (Sa) | Vaccines |
| AU2001239873A1 (en) * | 2000-02-24 | 2001-09-03 | The Board Of Trustees Of The Leland Stanford Junior University | Adjuvant treatment by in vivo activation of dendritic cells |
| KR20020091170A (ko) * | 2000-03-31 | 2002-12-05 | 아이덱 파마슈티칼즈 코포레이션 | B 세포 림프종의 치료를 위한 항-사이토카인 항체 또는길항제 및 항-cd20의 조합된 사용 |
-
2002
- 2002-11-25 TW TW091134176A patent/TW200303759A/zh unknown
- 2002-11-26 EP EP02794058A patent/EP1450858A2/en not_active Withdrawn
- 2002-11-26 NZ NZ565420A patent/NZ565420A/en not_active IP Right Cessation
- 2002-11-26 MX MXPA04004998A patent/MXPA04004998A/es unknown
- 2002-11-26 JP JP2003546932A patent/JP2006502080A/ja active Pending
- 2002-11-26 WO PCT/US2002/038098 patent/WO2003045431A2/en not_active Ceased
- 2002-11-26 CN CN028275985A patent/CN1617742B/zh not_active Expired - Fee Related
- 2002-11-26 BR BRPI0214457-3A patent/BR0214457A/pt not_active IP Right Cessation
- 2002-11-26 HU HU0500999A patent/HUP0500999A2/hu unknown
- 2002-11-26 CA CA002468320A patent/CA2468320A1/en not_active Abandoned
- 2002-11-26 AU AU2002359516A patent/AU2002359516B2/en not_active Ceased
- 2002-11-26 US US10/304,616 patent/US20030138413A1/en not_active Abandoned
-
2004
- 2004-05-26 ZA ZA200404113A patent/ZA200404113B/xx unknown
- 2004-06-25 NO NO20042697A patent/NO20042697L/no not_active Application Discontinuation
-
2005
- 2005-11-18 JP JP2005334633A patent/JP2006131638A/ja active Pending
-
2008
- 2008-09-19 US US12/234,361 patent/US20090087440A1/en not_active Abandoned
-
2009
- 2009-12-01 JP JP2009274004A patent/JP2010053140A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200404113B (en) | 2006-03-29 |
| JP2006131638A (ja) | 2006-05-25 |
| BR0214457A (pt) | 2006-11-21 |
| AU2002359516A1 (en) | 2003-06-10 |
| AU2002359516B2 (en) | 2006-02-02 |
| JP2010053140A (ja) | 2010-03-11 |
| TW200303759A (en) | 2003-09-16 |
| WO2003045431A2 (en) | 2003-06-05 |
| CN1617742A (zh) | 2005-05-18 |
| CA2468320A1 (en) | 2003-06-05 |
| NZ565420A (en) | 2009-09-25 |
| JP2006502080A (ja) | 2006-01-19 |
| US20090087440A1 (en) | 2009-04-02 |
| MXPA04004998A (es) | 2005-04-08 |
| EP1450858A2 (en) | 2004-09-01 |
| US20030138413A1 (en) | 2003-07-24 |
| CN1617742B (zh) | 2010-10-27 |
| WO2003045431A3 (en) | 2004-01-22 |
| HUP0500999A2 (en) | 2007-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20042697L (no) | Fremgangsmater for behandling av kreft ved anvendelse av en kombinasjon av en tumoravledet dendrittcelleinhiberende faktor-antagonist og en Toll-lignende reseptorantagonist | |
| DK2283867T3 (da) | Fremgangsmåder til behandling ved anvendelse af anti-ErbB antistof-maytansinoidkonjugater | |
| NO20033995D0 (no) | Fremgangsmåte ved frakturering av en underjordisk formasjon | |
| DE60040956D1 (de) | Riss- und splitterbeständiger Bohrlochzement | |
| IL166625A0 (en) | Combination of vegf receptor tyrosine kinase inhibitors for treatment of cancer | |
| DE60208661D1 (de) | Diaminothiazole und ihre verwendung als cyclinabhängige kinase inhibitoren | |
| DK3342411T3 (da) | Rapamycinderivat til behandling af pancreascancer | |
| PL363339A1 (en) | Method of checking ballast profile | |
| NO20031489D0 (no) | Fremgangsmåte og anordning ved trekkbar broplugg | |
| NO20033684L (no) | Behandling av refrakt¶re tumorer ved anvendelse av epotilonderivater | |
| NO20032966D0 (no) | Fremgangsmåte og anordning ved utboring av sementplugger | |
| NO20033429L (no) | Fremgangsmåter for behandling av inflamatoriske og immunsykdommer ved anvendelse av inhibitorer av I-kappa-B kinase (IKK) | |
| PL359556A1 (en) | Method - use of cox-2 inhibitors for preventing immunodeficiency | |
| EP1390052A4 (en) | INHIBITION OF JUN KINASE | |
| PL1781321T3 (pl) | Sposób leczenia raka zawierający antagonistę VEGF-B | |
| AU2002308522A8 (en) | Methods for inhibiting tumor cell proliferation | |
| AU2003231084A8 (en) | Identification of biomarkers for detecting prostate cancer | |
| EP1569516A4 (en) | METHOD OF INHIBITING CANCER AND TARGET EDUCATION | |
| IS2536B (is) | Lyfjablanda úr PDE4 eða PDE3/4 tálma og histamínviðtakamótlyfi | |
| EP1534317A4 (en) | N-TERMINAL TRONQUEE GALECTIN-3 AND ANTIBODIES FOR THE TREATMENT OF CANCER | |
| EP1378752A4 (en) | METHOD FOR QUANTIFYING ANTIGEN EXPRESSION | |
| GB0124272D0 (en) | Method of delivering money | |
| NO20010803L (no) | Fremgangsmate ved alkylering og nye hydroksyfenylbenztriazoler | |
| NO20006537D0 (no) | Fremgangsmåte og anordning ved bunndetektor | |
| AU2003903274A0 (en) | Method of assessing cancer risk |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |