NO20042497L - 4,4-diflour-1,2,3,4-tetrahydro-5H-1-benzazepinderivater og salter av disse - Google Patents
4,4-diflour-1,2,3,4-tetrahydro-5H-1-benzazepinderivater og salter av disseInfo
- Publication number
- NO20042497L NO20042497L NO20042497A NO20042497A NO20042497L NO 20042497 L NO20042497 L NO 20042497L NO 20042497 A NO20042497 A NO 20042497A NO 20042497 A NO20042497 A NO 20042497A NO 20042497 L NO20042497 L NO 20042497L
- Authority
- NO
- Norway
- Prior art keywords
- difluoro
- tetrahydro
- salts
- benzazepine derivatives
- benzazepine
- Prior art date
Links
- DTSDJGNXLLPHFA-UHFFFAOYSA-N 4,4-difluoro-1,2,3,5-tetrahydro-1-benzazepine Chemical class C1C(F)(F)CCNC2=CC=CC=C21 DTSDJGNXLLPHFA-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- 101800001144 Arg-vasopressin Proteins 0.000 abstract 1
- 208000003450 Neurogenic Diabetes Insipidus Diseases 0.000 abstract 1
- 102100026383 Vasopressin-neurophysin 2-copeptin Human genes 0.000 abstract 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 abstract 1
- 208000028235 central diabetes insipidus Diseases 0.000 abstract 1
- 201000010064 diabetes insipidus Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 201000005119 neurohypophyseal diabetes insipidus Diseases 0.000 abstract 1
- 206010029446 nocturia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001350909 | 2001-11-16 | ||
| JP2002252931 | 2002-08-30 | ||
| PCT/JP2002/011842 WO2003042181A1 (en) | 2001-11-16 | 2002-11-13 | 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivatives or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20042497L true NO20042497L (no) | 2004-07-21 |
Family
ID=26624548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20042497A NO20042497L (no) | 2001-11-16 | 2004-06-15 | 4,4-diflour-1,2,3,4-tetrahydro-5H-1-benzazepinderivater og salter av disse |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7169772B2 (ja) |
| EP (1) | EP1445253B1 (ja) |
| JP (1) | JP4075064B2 (ja) |
| KR (1) | KR100632882B1 (ja) |
| CN (1) | CN1323076C (ja) |
| AT (1) | ATE438626T1 (ja) |
| AU (1) | AU2002349773B2 (ja) |
| BR (1) | BR0214224A (ja) |
| CA (1) | CA2464069A1 (ja) |
| DE (1) | DE60233251D1 (ja) |
| ES (1) | ES2327620T3 (ja) |
| HU (1) | HUP0402235A2 (ja) |
| MX (1) | MXPA04004501A (ja) |
| NO (1) | NO20042497L (ja) |
| PL (1) | PL369999A1 (ja) |
| RU (1) | RU2268882C1 (ja) |
| WO (1) | WO2003042181A1 (ja) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| JP2006508339A (ja) | 2002-09-20 | 2006-03-09 | プロメガ コーポレイション | シトクロムｐ４５０活性を測定するための発光を利用する方法およびプローブ |
| WO2004047730A2 (en) * | 2002-11-21 | 2004-06-10 | New York Blood Center | Compounds for inhibition of hiv infection by blocking hiv entry |
| WO2004096775A1 (ja) | 2003-04-28 | 2004-11-11 | Astellas Pharma Inc. | ４，４－ジフルオロ－１，２，３，４－テトラヒドロ－５ｈ－１－ベンゾアゼピン誘導体又はその塩 |
| WO2005090282A1 (en) | 2004-03-12 | 2005-09-29 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| EP2778234B1 (en) | 2005-05-31 | 2017-09-27 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| EP1935986B1 (en) | 2005-05-31 | 2014-04-16 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| NZ565080A (en) | 2005-07-22 | 2011-03-31 | Mochida Pharm Co Ltd | Novel heterocyclidene acetamide derivative |
| JP5164510B2 (ja) * | 2006-10-06 | 2013-03-21 | 日本曹達株式会社 | 含窒素複素環化合物および有害生物防除剤 |
| TW200835502A (en) | 2006-12-26 | 2008-09-01 | Daiichi Sankyo Co Ltd | Thiazepine derivatives |
| US20100016285A1 (en) * | 2007-01-24 | 2010-01-21 | Mochida Pharmaceutical Co., Ltd. | Heterocyclidene-n-(aryl) acetamide derivative |
| PE20081692A1 (es) | 2007-01-24 | 2008-12-18 | Mochida Pharm Co Ltd | Nuevo derivado de heterocicliden acetamida |
| EP2133331A4 (en) * | 2007-04-11 | 2011-06-22 | Kissei Pharmaceutical | FIVE-GLASS HETEROCYCLIC DERIVATIVE AND ITS USE IN MEDICAL PURPOSES |
| CA2988753A1 (en) | 2007-08-06 | 2009-02-12 | Serenity Pharmaceuticals, Llc | Methods and devices for desmopressin drug delivery |
| US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
| US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
| JP5767103B2 (ja) * | 2008-05-21 | 2015-08-19 | フエリング・インターナシヨナル・センター・エス・アー | 夜間頻尿によって妨げられない睡眠の初期期間を増加させるための口腔内崩壊デスモプレシン |
| UY32940A (es) | 2009-10-27 | 2011-05-31 | Bayer Cropscience Ag | Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas |
| SI2860175T1 (en) * | 2012-06-11 | 2018-04-30 | Tacurion | Method for producing 4,4,7-trifluoro-1,2,3,4-tetrahydro-5h-1-benzazepine compound and intermediate for synthesis thereof |
| CN104884436B (zh) * | 2012-12-26 | 2017-06-13 | 株式会社三和化学研究所 | 苯并氮杂衍生物及其医药用途 |
| WO2015116867A1 (en) | 2014-01-29 | 2015-08-06 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| CN105310978A (zh) * | 2014-08-04 | 2016-02-10 | 李峰 | 一种含有活性成分盐酸考尼伐坦的药物组合物及其制剂 |
| CA3133929A1 (en) | 2019-04-19 | 2020-10-22 | Lin Zhi | Crystalline forms and methods of producing crystalline forms of a compound |
| CN112079826B (zh) * | 2020-09-17 | 2022-07-29 | 广州中医药大学(广州中医药研究院) | 一类甾体合成酶抑制剂及其治疗应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1039999A (zh) * | 1988-07-30 | 1990-02-28 | 刘晓非 | 多层复合装饰板及制作方法 |
| TW270927B (ja) | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| AU684537B2 (en) * | 1993-08-26 | 1997-12-18 | Yamanouchi Pharmaceutical Co., Ltd. | Benzazepine derivative, pharmaceutical composition containing the same, and intermediate for the same |
| TW359669B (en) * | 1995-12-15 | 1999-06-01 | Otsuka Pharma Co Ltd | Benzazepine derivatives |
| JPH09221475A (ja) * | 1996-02-13 | 1997-08-26 | Yamanouchi Pharmaceut Co Ltd | 新規なオキシム誘導体 |
| AR011913A1 (es) | 1997-03-06 | 2000-09-13 | Yamano Masaki | Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos. |
-
2002
- 2002-11-13 CN CNB028226046A patent/CN1323076C/zh not_active Expired - Fee Related
- 2002-11-13 HU HU0402235A patent/HUP0402235A2/hu unknown
- 2002-11-13 BR BR0214224-4A patent/BR0214224A/pt not_active IP Right Cessation
- 2002-11-13 AT AT02781759T patent/ATE438626T1/de not_active IP Right Cessation
- 2002-11-13 EP EP02781759A patent/EP1445253B1/en not_active Expired - Lifetime
- 2002-11-13 ES ES02781759T patent/ES2327620T3/es not_active Expired - Lifetime
- 2002-11-13 DE DE60233251T patent/DE60233251D1/de not_active Expired - Lifetime
- 2002-11-13 RU RU2004118063/04A patent/RU2268882C1/ru not_active IP Right Cessation
- 2002-11-13 CA CA002464069A patent/CA2464069A1/en not_active Abandoned
- 2002-11-13 JP JP2003544017A patent/JP4075064B2/ja not_active Expired - Fee Related
- 2002-11-13 MX MXPA04004501A patent/MXPA04004501A/es active IP Right Grant
- 2002-11-13 WO PCT/JP2002/011842 patent/WO2003042181A1/ja not_active Ceased
- 2002-11-13 US US10/495,494 patent/US7169772B2/en not_active Expired - Fee Related
- 2002-11-13 KR KR1020047007126A patent/KR100632882B1/ko not_active Expired - Fee Related
- 2002-11-13 AU AU2002349773A patent/AU2002349773B2/en not_active Ceased
- 2002-11-13 PL PL02369999A patent/PL369999A1/xx not_active Application Discontinuation
-
2004
- 2004-06-15 NO NO20042497A patent/NO20042497L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2004118063A (ru) | 2006-01-10 |
| HUP0402235A2 (hu) | 2005-02-28 |
| DE60233251D1 (de) | 2009-09-17 |
| MXPA04004501A (es) | 2004-08-11 |
| EP1445253B1 (en) | 2009-08-05 |
| EP1445253A4 (en) | 2005-11-16 |
| KR20050044401A (ko) | 2005-05-12 |
| ATE438626T1 (de) | 2009-08-15 |
| BR0214224A (pt) | 2004-09-21 |
| US7169772B2 (en) | 2007-01-30 |
| JP4075064B2 (ja) | 2008-04-16 |
| AU2002349773B2 (en) | 2007-12-13 |
| WO2003042181A1 (en) | 2003-05-22 |
| PL369999A1 (en) | 2005-05-16 |
| CA2464069A1 (en) | 2003-05-22 |
| RU2268882C1 (ru) | 2006-01-27 |
| EP1445253A1 (en) | 2004-08-11 |
| US20050004103A1 (en) | 2005-01-06 |
| JPWO2003042181A1 (ja) | 2005-03-10 |
| CN1323076C (zh) | 2007-06-27 |
| KR100632882B1 (ko) | 2006-10-13 |
| ES2327620T3 (es) | 2009-11-02 |
| CN1585752A (zh) | 2005-02-23 |
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