NO20034641L - Kontroll av fremgangsmatefuktighet for fremstilling av store, porose partikler - Google Patents
Kontroll av fremgangsmatefuktighet for fremstilling av store, porose partiklerInfo
- Publication number
- NO20034641L NO20034641L NO20034641A NO20034641A NO20034641L NO 20034641 L NO20034641 L NO 20034641L NO 20034641 A NO20034641 A NO 20034641A NO 20034641 A NO20034641 A NO 20034641A NO 20034641 L NO20034641 L NO 20034641L
- Authority
- NO
- Norway
- Prior art keywords
- production
- humidity control
- particles
- porous particles
- approx
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Glanulating (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Silicon Compounds (AREA)
Abstract
Forstøvningstørkede partikler som har spesifiserte aerodynamiske karakteristikker, fremstilles ved å atomisere en væskemating og å bringe væskematingen i kontakt med en tørregass, for eksempel luft eller nitrogen. Fuktigheten i tørregassen reguleres til en verdi, uttrykt for eksempel som duggpunkt, som er kjent for å produsere partikler med en spesifisert densitet ved lett banking eller aerodynamisk diameter. Partikler som har en volum-median-geometrisk diameter større enn ca. 5 (jm og en densitet ved lett banking på mindre enn ca. 0,4 g/cmforetrekkes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/837,620 US6848197B2 (en) | 2001-04-18 | 2001-04-18 | Control of process humidity to produce large, porous particles |
| PCT/US2002/012320 WO2002085326A2 (en) | 2001-04-18 | 2002-04-17 | Large, porous particles produced controlling humidity during a spray drying process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20034641L true NO20034641L (no) | 2003-10-17 |
| NO20034641D0 NO20034641D0 (no) | 2003-10-17 |
Family
ID=25274976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20034641A NO20034641D0 (no) | 2001-04-18 | 2003-10-17 | Kontroll av fremgangsmåtefuktighet for fremstilling av store, poröse partikler |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6848197B2 (no) |
| EP (1) | EP1379219B1 (no) |
| JP (1) | JP4203564B2 (no) |
| CN (1) | CN100522142C (no) |
| AT (1) | ATE418326T1 (no) |
| AU (1) | AU2002258865B2 (no) |
| CA (1) | CA2439818C (no) |
| CY (1) | CY1108803T1 (no) |
| DE (1) | DE60230495D1 (no) |
| DK (1) | DK1379219T3 (no) |
| ES (1) | ES2318007T3 (no) |
| IL (2) | IL157569A0 (no) |
| MX (1) | MXPA03009561A (no) |
| NO (1) | NO20034641D0 (no) |
| NZ (1) | NZ527884A (no) |
| PL (1) | PL371979A1 (no) |
| PT (1) | PT1379219E (no) |
| WO (1) | WO2002085326A2 (no) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858199B1 (en) * | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
| US6848197B2 (en) * | 2001-04-18 | 2005-02-01 | Advanced Inhalation Research, Inc. | Control of process humidity to produce large, porous particles |
| ES2415654T3 (es) | 2001-11-20 | 2013-07-26 | Civitas Therapeutics, Inc. | Composiciones particuladas mejoradas para suministro pulmonar |
| PL372247A1 (en) | 2002-02-01 | 2005-07-11 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus |
| US7008644B2 (en) * | 2002-03-20 | 2006-03-07 | Advanced Inhalation Research, Inc. | Method and apparatus for producing dry particles |
| US20040197413A1 (en) * | 2003-04-04 | 2004-10-07 | Genteric, Inc. | Spray dry coacervation systems and methods |
| CL2004001884A1 (es) * | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| US20060105051A1 (en) * | 2004-11-18 | 2006-05-18 | Blair Jackson | Manufacture of particles for pulmonary drug delivery by carbon dioxide assisted nebulization |
| JP2008514648A (ja) * | 2004-12-16 | 2008-05-08 | アドバンスト インハレーション リサーチ,インコーポレイテッド | 肺疾患のための組成物および方法 |
| FR2899581B1 (fr) * | 2006-04-07 | 2008-06-27 | Guerbet Sa | Procede d'atomisation du ioxilan |
| JP5244189B2 (ja) * | 2007-09-24 | 2013-07-24 | インハレイション・サイエンシズ・スウェーデン・エイビイ | 乾燥製剤を製造するためのシステムおよび方法 |
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| TWI792140B (zh) | 2009-05-29 | 2023-02-11 | 美商沛爾醫療股份有限公司 | 用於經由呼吸道遞送二或更多種活性藥劑的組成物、方法與系統 |
| WO2011154014A1 (en) * | 2010-06-11 | 2011-12-15 | Gea Process Engineering A/S | Controlled humidity drying |
| WO2014074797A1 (en) | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
| US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| TR201902687T4 (tr) | 2013-03-15 | 2019-03-21 | Pearl Therapeutics Inc | İri parçacıklı kristal malzemelerin koşullandırılması için yöntemler ve sistemler. |
| WO2014178891A1 (en) | 2013-04-30 | 2014-11-06 | Otitopic Inc. | Dry powder formulations and methods of use |
| US9993488B2 (en) | 2014-02-20 | 2018-06-12 | Otitopic Inc. | Dry powder formulations for inhalation |
| MA40910A (fr) | 2014-11-07 | 2017-09-12 | Civitas Therapeutics Inc | Poudres de rapamycine pour administration pulmonaire |
| KR101626675B1 (ko) * | 2014-11-12 | 2016-06-01 | 엘지전자 주식회사 | 공기조화기 및 그 제어방법 |
| EP4026568A1 (en) | 2015-04-17 | 2022-07-13 | CureVac Real Estate GmbH | Lyophilization of rna |
| CA2984339A1 (en) | 2015-05-01 | 2016-11-10 | Civitas Therapeutics, Inc. | Zolmitriptan powders for pulmonary delivery |
| CN107635587A (zh) | 2015-05-20 | 2018-01-26 | 库瑞瓦格股份公司 | 包含长链rna的干燥粉末组合物 |
| EP3297682B1 (en) | 2015-05-20 | 2021-07-14 | CureVac AG | Dry powder composition comprising long-chain rna |
| KR20180052566A (ko) | 2015-07-02 | 2018-05-18 | 키비타스 테라퓨틱스, 인코포레이티드. | 폐 전달용 트립탄 분말 |
| CH711362B1 (de) * | 2015-07-29 | 2019-11-15 | Tecan Schweiz Ag | Steuergerät für relative Feuchtigkeit. |
| WO2018132822A1 (en) | 2017-01-16 | 2018-07-19 | Envirostar, Llc | Dryer control systems and methods |
| ES2901875T3 (es) | 2017-04-24 | 2022-03-24 | Cocrystal Pharma Inc | Derivados de la pirrolopirimidina útiles como inhibidores de la replicación del virus de la influenza |
| US11878023B2 (en) | 2017-10-25 | 2024-01-23 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for delivering pharmaceutical agents |
| WO2019084292A1 (en) | 2017-10-25 | 2019-05-02 | Arizona Board Of Regents On Behalf Of The University Of Arizona | COMPOSITIONS AND METHODS FOR ADMINISTERING PHARMACEUTICAL AGENTS |
| US11904054B2 (en) | 2018-01-19 | 2024-02-20 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for delivering pharmaceutical agents |
| US12357631B2 (en) | 2018-07-27 | 2025-07-15 | Cocrystal Pharma, Inc. | Pyrrolo[2,3-B]pyridin derivatives as inhibitors of influenza virus replication |
| CN113286793B (zh) | 2018-09-10 | 2024-04-05 | 共结晶制药公司 | 吡咯并吡嗪和吡啶并三嗪类流感病毒复制抑制剂 |
| IL282018B2 (en) | 2018-10-17 | 2025-06-01 | Cocrystal Pharma Inc | Combinations of inhibitors of influenza virus replication |
| EP3887355A1 (en) | 2018-11-26 | 2021-10-06 | Cocrystal Pharma, Inc. | Inhibitors of influenza virus replication |
| CA3138530A1 (en) | 2019-04-29 | 2020-11-05 | Insmed Incorporated | Dry powder compositions of treprostinil prodrugs and methods of use thereof |
| WO2021188620A1 (en) | 2020-03-17 | 2021-09-23 | Cocrystal Pharma Inc. | Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication |
| WO2021206876A1 (en) | 2020-04-10 | 2021-10-14 | Cocrystal Pharma, Inc. | Inhibitors of norovirus and coronavirus replication |
| WO2021219230A1 (en) | 2020-04-30 | 2021-11-04 | Paolo Fiorina | Antiviral treatment |
| KR20240055745A (ko) | 2021-08-03 | 2024-04-29 | 코크리스탈 파마, 아이엔씨. | 코로나바이러스 억제제 |
| WO2023150747A1 (en) | 2022-02-07 | 2023-08-10 | Insmed Incorporated | Dry powder compositions of bedaquiline and salts and methods of use thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3495458A (en) | 1967-11-20 | 1970-02-17 | Pillsbury Co | Continuous sampling gas testing apparatus for use in dusty atmospheres |
| US4422900A (en) | 1981-11-25 | 1983-12-27 | Olin Corporation | Spray drying apparatus for available chlorine-containing compounds |
| AU7908791A (en) | 1990-05-08 | 1991-11-27 | Liposome Technology, Inc. | Direct spray-dried drug/lipid powder composition |
| US5632100A (en) | 1993-11-17 | 1997-05-27 | Niro Holding A/S | Process and a spray drying apparatus for producing an agglomerated powder |
| US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| US5833647A (en) * | 1995-10-10 | 1998-11-10 | The Penn State Research Foundation | Hydrogels or lipogels with enhanced mass transfer for transdermal drug delivery |
| US6022737A (en) | 1995-11-02 | 2000-02-08 | Amgen Inc. | Formulations for non-viral in vivo transfection in the lungs |
| PT885002E (pt) * | 1996-03-04 | 2011-07-14 | Massachusetts Inst Technology | Materiais e métodos para aumento da internalização celular |
| AUPN940796A0 (en) | 1996-04-23 | 1996-05-16 | F.H. Faulding & Co. Limited | Taste masked pharmaceutical compositions |
| USRE37053E1 (en) * | 1996-05-24 | 2001-02-13 | Massachusetts Institute Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US6254854B1 (en) * | 1996-05-24 | 2001-07-03 | The Penn Research Foundation | Porous particles for deep lung delivery |
| IL142432A0 (en) * | 1998-10-05 | 2002-03-10 | Penn State Res Found | Compositions and methods for enhancing receptor-mediated cellular internalization |
| CA2376937C (en) | 1999-06-30 | 2009-01-06 | Inhale Therapeutics Systems Inc. | Spray drying process for preparing dry powders |
| JP2003507411A (ja) | 1999-08-25 | 2003-02-25 | アドバンスト インハレーション リサーチ,インコーポレイテッド | 噴霧乾燥大多孔性粒子製剤 |
| US6586008B1 (en) * | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
| WO2001023821A1 (en) | 1999-09-29 | 2001-04-05 | Glaxo Group Limited | Methods and systems for controlling evaporative drying processes using environmental equivalency |
| US6848197B2 (en) * | 2001-04-18 | 2005-02-01 | Advanced Inhalation Research, Inc. | Control of process humidity to produce large, porous particles |
-
2001
- 2001-04-18 US US09/837,620 patent/US6848197B2/en not_active Expired - Lifetime
-
2002
- 2002-04-17 CA CA002439818A patent/CA2439818C/en not_active Expired - Lifetime
- 2002-04-17 PL PL02371979A patent/PL371979A1/xx not_active Application Discontinuation
- 2002-04-17 IL IL15756902A patent/IL157569A0/xx active IP Right Grant
- 2002-04-17 DE DE60230495T patent/DE60230495D1/de not_active Expired - Lifetime
- 2002-04-17 DK DK02728839T patent/DK1379219T3/da active
- 2002-04-17 MX MXPA03009561A patent/MXPA03009561A/es unknown
- 2002-04-17 NZ NZ527884A patent/NZ527884A/en unknown
- 2002-04-17 WO PCT/US2002/012320 patent/WO2002085326A2/en not_active Ceased
- 2002-04-17 ES ES02728839T patent/ES2318007T3/es not_active Expired - Lifetime
- 2002-04-17 JP JP2002588738A patent/JP4203564B2/ja not_active Expired - Lifetime
- 2002-04-17 CN CN02808496.9A patent/CN100522142C/zh not_active Expired - Lifetime
- 2002-04-17 AT AT02728839T patent/ATE418326T1/de active
- 2002-04-17 EP EP02728839A patent/EP1379219B1/en not_active Expired - Lifetime
- 2002-04-17 PT PT02728839T patent/PT1379219E/pt unknown
- 2002-04-17 AU AU2002258865A patent/AU2002258865B2/en not_active Expired
-
2003
- 2003-08-25 IL IL157569A patent/IL157569A/en unknown
- 2003-10-17 NO NO20034641A patent/NO20034641D0/no not_active Application Discontinuation
-
2004
- 2004-10-29 US US10/977,088 patent/US7469488B2/en not_active Expired - Lifetime
-
2009
- 2009-03-20 CY CY20091100311T patent/CY1108803T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2439818A1 (en) | 2002-10-31 |
| US20030017113A1 (en) | 2003-01-23 |
| JP4203564B2 (ja) | 2009-01-07 |
| US20050058607A1 (en) | 2005-03-17 |
| CA2439818C (en) | 2008-06-17 |
| IL157569A (en) | 2008-04-13 |
| CN1503661A (zh) | 2004-06-09 |
| AU2002258865B2 (en) | 2006-01-12 |
| NZ527884A (en) | 2006-02-24 |
| EP1379219A2 (en) | 2004-01-14 |
| DE60230495D1 (de) | 2009-02-05 |
| HK1061654A1 (en) | 2004-09-30 |
| DK1379219T3 (da) | 2009-03-23 |
| US6848197B2 (en) | 2005-02-01 |
| ES2318007T3 (es) | 2009-05-01 |
| CN100522142C (zh) | 2009-08-05 |
| US7469488B2 (en) | 2008-12-30 |
| WO2002085326A2 (en) | 2002-10-31 |
| CY1108803T1 (el) | 2012-05-23 |
| IL157569A0 (en) | 2004-03-28 |
| PT1379219E (pt) | 2009-03-24 |
| EP1379219B1 (en) | 2008-12-24 |
| WO2002085326A3 (en) | 2003-04-10 |
| MXPA03009561A (es) | 2004-02-12 |
| NO20034641D0 (no) | 2003-10-17 |
| PL371979A1 (en) | 2005-07-11 |
| ATE418326T1 (de) | 2009-01-15 |
| JP2005508853A (ja) | 2005-04-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |