NO20030856L - Membranpenetrerende peptider og anvendelse av disse - Google Patents
Membranpenetrerende peptider og anvendelse av disseInfo
- Publication number
- NO20030856L NO20030856L NO20030856A NO20030856A NO20030856L NO 20030856 L NO20030856 L NO 20030856L NO 20030856 A NO20030856 A NO 20030856A NO 20030856 A NO20030856 A NO 20030856A NO 20030856 L NO20030856 L NO 20030856L
- Authority
- NO
- Norway
- Prior art keywords
- penetrating peptides
- membrane penetrating
- interest
- vivo
- cells
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 4
- 230000000149 penetrating effect Effects 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000969 carrier Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22764700P | 2000-08-25 | 2000-08-25 | |
| GBGB0103110.3A GB0103110D0 (en) | 2000-08-25 | 2001-02-07 | A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1 |
| PCT/US2001/026421 WO2002018572A2 (en) | 2000-08-25 | 2001-08-23 | Membrane penetrating peptides and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20030856D0 NO20030856D0 (no) | 2003-02-24 |
| NO20030856L true NO20030856L (no) | 2003-04-24 |
| NO332050B1 NO332050B1 (no) | 2012-06-11 |
Family
ID=26245698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20030856A NO332050B1 (no) | 2000-08-25 | 2003-02-24 | Fusjonsprotein for avlevering av et organisk molekyl inn i en celle |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1360311B1 (no) |
| AT (1) | ATE391791T1 (no) |
| AU (1) | AU8524901A (no) |
| CA (1) | CA2420350C (no) |
| IL (1) | IL154589A0 (no) |
| MX (1) | MXPA03001622A (no) |
| NO (1) | NO332050B1 (no) |
| NZ (1) | NZ524386A (no) |
| WO (1) | WO2002018572A2 (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030086927A1 (en) | 1995-11-01 | 2003-05-08 | University Of Southern California | Expression of cyclin G1 in tumors |
| EP2008664B1 (en) | 1997-04-10 | 2012-08-29 | University Of Southern California | Modified proteins which bind extracellular matrix components |
| FR2781674B1 (fr) * | 1998-07-31 | 2002-06-28 | Inst Nat Sante Rech Med | Utilisation de nouveaux agents inducteurs de mort cellulaire en synergie avec les interferons |
| EP1146869A2 (en) | 1999-01-27 | 2001-10-24 | University Of South Florida | Inhibition of stat3 signal transduction for human cancer therapy |
| WO2003062398A2 (en) * | 2002-01-23 | 2003-07-31 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | NEW TUMOR SUPPRESSOR GENE, p28ING5 |
| CA2477429A1 (en) * | 2002-01-29 | 2003-08-07 | Robert A. Uger | Targeted immunogens |
| KR20030078115A (ko) * | 2002-03-28 | 2003-10-08 | (주)코아바이오텍 | 펩타이드 유전자 전달매체 및 이를 이용한 유전자 전달 방법 |
| WO2003097671A1 (en) * | 2002-03-29 | 2003-11-27 | Creagene Inc. | Cytoplasmic transduction peptides and uses thereof |
| SE0201863D0 (en) * | 2002-06-18 | 2002-06-18 | Cepep Ab | Cell penetrating peptides |
| US7638122B2 (en) | 2003-03-07 | 2009-12-29 | University Of South Florida | Stat3 antagonists and their use as vaccines against cancer |
| US20070178066A1 (en) | 2003-04-21 | 2007-08-02 | Hall Frederick L | Pathotropic targeted gene delivery system for cancer and other disorders |
| BRPI0418273A (pt) * | 2003-12-31 | 2007-05-02 | Sanofi Pasteur Inc | imunógenos alvejados |
| JP5043672B2 (ja) | 2005-10-28 | 2012-10-10 | 田辺三菱製薬株式会社 | 新規細胞膜透過ペプチド |
| WO2007071448A2 (en) | 2005-12-23 | 2007-06-28 | Partnership & Corp. Technology Transfer | Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of muscle relaxation |
| US7981446B2 (en) * | 2007-11-26 | 2011-07-19 | Forhumantech. Co., Ltd. | Pharmaceutical compositions and methods for delivering nucleic acids into cells |
| EP2250278B1 (en) | 2008-02-21 | 2023-04-05 | Burnham Institute for Medical Research | Methods and compositions related to peptides and proteins with c-terminal elements |
| US8710005B2 (en) | 2009-04-10 | 2014-04-29 | Toagosei Co., Ltd. | Neuronal differentiation-inducing peptide and use thereof |
| CN102869384B (zh) | 2009-06-22 | 2016-01-13 | 伯纳姆医学研究所 | 使用带有c-端元件的肽和蛋白质的方法和组合物 |
| WO2011013700A1 (ja) * | 2009-07-29 | 2011-02-03 | 東亞合成株式会社 | キャリアペプチドフラグメント及びその利用 |
| JP5858284B2 (ja) * | 2009-07-29 | 2016-02-10 | 東亞合成株式会社 | キャリアペプチドフラグメントとその利用 |
| WO2011013698A1 (ja) * | 2009-07-29 | 2011-02-03 | 東亞合成株式会社 | キャリアペプチドフラグメント及びその利用 |
| WO2011052679A1 (ja) | 2009-11-02 | 2011-05-05 | 東亞合成株式会社 | 細胞増殖促進ペプチド及びその利用 |
| JP5854283B2 (ja) | 2010-06-04 | 2016-02-09 | 東亞合成株式会社 | 細胞増殖促進ペプチド及びその利用 |
| US9238796B2 (en) | 2010-06-04 | 2016-01-19 | Toagosei Co. Ltd. | Cell growth-promoting peptide and use thereof |
| WO2013180011A1 (ja) | 2012-05-28 | 2013-12-05 | 東亞合成株式会社 | 抗菌ペプチド及びその利用 |
| WO2014061749A1 (ja) | 2012-10-18 | 2014-04-24 | 東亞合成株式会社 | ２型ｔｎｆ受容体の発現を抑制する合成ペプチド及びその利用 |
| KR101671114B1 (ko) | 2015-06-26 | 2016-10-31 | 충북대학교 산학협력단 | Ｕｌｋ２로부터 유래된 핵 위치화 신호 펩타이드 및 이의 용도 |
| IL310597A (en) * | 2021-08-06 | 2024-04-01 | Univ Pennsylvania | Preparations and methods for the treatment and prevention of misfolded proteins |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962415A (en) * | 1996-09-20 | 1999-10-05 | Bristol-Myers Squibb Co. | Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods of use thereof |
| WO1998049325A1 (en) * | 1997-04-28 | 1998-11-05 | Mcgill University | Reporter fusion proteins, expression vectors and transfected cell lines thereof for the analysis of nuclear transport |
| SE9801055D0 (sv) * | 1998-03-25 | 1998-03-25 | Inst Of Molecul & Cell Biology | Use of growth hormone binding protein (GHBP) |
| JP2003514564A (ja) * | 1999-11-24 | 2003-04-22 | エムシーエス マイクロ キャリア システムズ ゲーエムベーハー | 核局在化シグナルまたはタンパク質導入領域の多量体を含むポリペプチド、および分子を細胞内へ移入するためのその使用法 |
| CN1254234C (zh) * | 2000-06-09 | 2006-05-03 | 莱古伦公司 | 质粒dna(lipogenestm)和含细胞核定位信号/促融合肽缀合物的治疗剂包封到定向脂质体复合体中 |
-
2001
- 2001-08-23 NZ NZ524386A patent/NZ524386A/en not_active IP Right Cessation
- 2001-08-23 EP EP01964392A patent/EP1360311B1/en not_active Expired - Lifetime
- 2001-08-23 CA CA2420350A patent/CA2420350C/en not_active Expired - Lifetime
- 2001-08-23 AU AU8524901A patent/AU8524901A/xx active Pending
- 2001-08-23 MX MXPA03001622A patent/MXPA03001622A/es active IP Right Grant
- 2001-08-23 WO PCT/US2001/026421 patent/WO2002018572A2/en not_active Ceased
- 2001-08-23 AT AT01964392T patent/ATE391791T1/de not_active IP Right Cessation
- 2001-08-23 IL IL15458901A patent/IL154589A0/xx unknown
-
2003
- 2003-02-24 NO NO20030856A patent/NO332050B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002018572A2 (en) | 2002-03-07 |
| ATE391791T1 (de) | 2008-04-15 |
| IL154589A0 (en) | 2003-09-17 |
| NZ524386A (en) | 2005-10-28 |
| NO332050B1 (no) | 2012-06-11 |
| EP1360311B1 (en) | 2008-04-09 |
| AU8524901A (en) | 2002-03-13 |
| CA2420350A1 (en) | 2002-03-07 |
| NO20030856D0 (no) | 2003-02-24 |
| MXPA03001622A (es) | 2004-09-06 |
| EP1360311A2 (en) | 2003-11-12 |
| CA2420350C (en) | 2010-07-13 |
| WO2002018572A3 (en) | 2003-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: AVENTISUB LLC, US |
|
| MK1K | Patent expired |