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NO20026282L - Inhibitorer av kobberholdige aminoksydaser - Google Patents

Inhibitorer av kobberholdige aminoksydaser

Info

Publication number
NO20026282L
NO20026282L NO20026282A NO20026282A NO20026282L NO 20026282 L NO20026282 L NO 20026282L NO 20026282 A NO20026282 A NO 20026282A NO 20026282 A NO20026282 A NO 20026282A NO 20026282 L NO20026282 L NO 20026282L
Authority
NO
Norway
Prior art keywords
inhibitors
copper
containing amine
amine oxidases
oxidases
Prior art date
Application number
NO20026282A
Other languages
English (en)
Norwegian (no)
Other versions
NO20026282D0 (no
Inventor
David John Smith
Markku Tapani Jalkanen
Ferenc Fueloep
Laszlo Lasar
Zsolt Szakonyi
Gabor Bernath
Original Assignee
Biotie Therapies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotie Therapies Corp filed Critical Biotie Therapies Corp
Publication of NO20026282D0 publication Critical patent/NO20026282D0/no
Publication of NO20026282L publication Critical patent/NO20026282L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20026282A 2000-07-05 2002-12-30 Inhibitorer av kobberholdige aminoksydaser NO20026282L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21634100P 2000-07-05 2000-07-05
PCT/FI2001/000637 WO2002002541A2 (fr) 2000-07-05 2001-07-04 Inhibiteur d'amine oxydases contenant du cuivre

Publications (2)

Publication Number Publication Date
NO20026282D0 NO20026282D0 (no) 2002-12-30
NO20026282L true NO20026282L (no) 2003-03-03

Family

ID=22806663

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20026283A NO20026283L (no) 2000-07-05 2002-12-30 Inhibitorer av kobberholdige aminosydaser
NO20026282A NO20026282L (no) 2000-07-05 2002-12-30 Inhibitorer av kobberholdige aminoksydaser

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20026283A NO20026283L (no) 2000-07-05 2002-12-30 Inhibitorer av kobberholdige aminosydaser

Country Status (14)

Country Link
US (2) US6624202B2 (fr)
EP (2) EP1313718A2 (fr)
JP (2) JP2004501962A (fr)
CN (2) CN1450997A (fr)
AU (3) AU2001282162A1 (fr)
CA (2) CA2414799A1 (fr)
HU (2) HUP0301336A3 (fr)
IL (2) IL153766A0 (fr)
NO (2) NO20026283L (fr)
NZ (2) NZ523464A (fr)
PL (2) PL360353A1 (fr)
RU (2) RU2003103291A (fr)
WO (2) WO2002002090A2 (fr)
ZA (2) ZA200300064B (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001282162A1 (en) 2000-07-05 2002-01-14 Biotie Therapies Corp. Inhibitors of copper-containing amine oxidases
US6982286B2 (en) * 2001-07-12 2006-01-03 Biotie Therapies Corp. Carbocyclic hydrazino inhibitors of copper-containing amine oxidases
CA2514573A1 (fr) 2003-01-27 2004-08-12 Astellas Pharma Inc. Derives de thiazole et leur utilisation en tant qu'inhibiteurs de vap-1
CA2520957C (fr) * 2003-03-31 2013-08-06 Sucampo Ag Procede de traitement de maladie vasculaire hyperpermeable
ATE447610T1 (de) * 2003-05-26 2009-11-15 Biotie Therapies Corp Kristalliner vap-1 und verwendung
FI20031927A0 (fi) * 2003-12-31 2003-12-31 Faron Pharmaceuticals Oy Terapeuttisesti vaikuttavia aineita ja niiden käyttö
FI20040136A0 (fi) * 2004-01-30 2004-01-30 Faron Pharmaceuticals Oy Erityisesti diabeetikoille soveltuvia koostumuksia
ES2342409T3 (es) * 2004-01-30 2010-07-06 Biotie Therapies Oyj Composiciones utiles especialmente para el tratamiento o prevencion del sindrome metabolico.
US8119651B2 (en) 2004-01-30 2012-02-21 Biotie Therapies Corp. Compositions useful especially for treatment or prevention of metabolic syndrome
FI20040270A0 (fi) * 2004-02-20 2004-02-20 Biotie Therapies Oyj Kuparia sisältävien amiinioksidaasien imhibiittoreina käyttökelpoiset hydratsinoalkoholijohdannaiset
WO2006011631A2 (fr) * 2004-07-27 2006-02-02 Astellas Pharma Inc. Derives de thiazole presentant une activite d'inhibition de la vap-1
CA2579889A1 (fr) * 2004-09-09 2006-03-16 Astellas Pharma Inc. Derives du thiazole presentant une activite inhibitrice de la proteine 1 d'adhesion vasculaire
JP4140630B2 (ja) * 2005-11-10 2008-08-27 Tdk株式会社 磁気ヘッドアセンブリ及び磁気ヘッドアセンブリの製造方法
US8636995B2 (en) * 2006-08-31 2014-01-28 Cardiac Pacemakers, Inc. Methods and devices to regulate stem cell homing
US20080058922A1 (en) * 2006-08-31 2008-03-06 Cardiac Pacemakers, Inc. Methods and devices employing vap-1 inhibitors
US8372399B2 (en) 2006-08-31 2013-02-12 Cardiac Pacemakers, Inc. Bispecific antibodies and agents to enhance stem cell homing
FI20061156A0 (fi) 2006-12-27 2006-12-27 Elina Kivi Uusia peptidejä
WO2009061830A1 (fr) * 2007-11-06 2009-05-14 Massachusetts Eye & Ear Infirmary Méthodes et compositions pour traiter des troubles associés à l'angiogenèse à l'aide d'un inhibiteur de la protéine-1 d'adhésion vasculaire (vap-1)
WO2009066152A2 (fr) 2007-11-21 2009-05-28 Pharmaxis Ltd. Inhibiteurs de ssao/vap-1 de type haloallylamines et leurs utilisations
TWI437986B (zh) 2008-01-31 2014-05-21 R Tech Ueno Ltd 噻唑衍生物及使用該衍生物作為vap-1抑制劑之用途
TWI490214B (zh) 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為vap-1抑制劑之用途
US8906642B2 (en) 2008-09-03 2014-12-09 Universitat Autonoma De Barcelona Methods and compositions for the treatment and diagnosis of haemorrhagic conversion
RU2400233C1 (ru) 2009-07-07 2010-09-27 Общество с ограниченной ответственностью "Вирфарм" Способ лечения заболеваний печени различного генеза
UA112154C2 (uk) 2009-09-08 2016-08-10 Біоті Терапіс Корп. Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів
CA2772689A1 (fr) 2009-09-16 2011-03-24 Astellas Pharma Inc. Compose de glycine
RU2010145439A (ru) 2010-11-08 2012-05-20 Виктор Вениаминович Тец (RU) Средство для лечения поражений печени, вызванных воздействием химических или биологических агентов
FI20115234A0 (fi) 2011-03-08 2011-03-08 Biotie Therapies Corp Uusia pyridatsinoni- ja pyridoniyhdisteitä
PT3002278T (pt) * 2011-03-15 2017-06-29 Astellas Pharma Inc Composto de guanidina
US20160113893A1 (en) 2013-06-12 2016-04-28 Proximagen Limited New therapeutic uses of enzyme inhibitors
HUE042625T2 (hu) 2014-04-15 2019-07-29 Pecsi Tudomanyegyetem Szemikarbazid-szenzitiv amin-oxidáz gátlók fájdalomcsillapítóként való alkalmazásra traumás neuropátiában és neurogén gyulladásban
WO2015189534A1 (fr) 2014-06-12 2015-12-17 Proximagen Limited Inhibiteurs de vap-1 pour le traitement de la dystrophie musculaire
RU2595868C1 (ru) 2015-03-27 2016-08-27 Виктор Вениаминович Тец Лекарственное средство с гепатопротекторной активностью
JP2018076236A (ja) 2015-06-05 2018-05-17 株式会社アールテック・ウエノ がんを処置するための医薬組成物
JP2019502672A (ja) 2015-12-07 2019-01-31 ベネボレンタイ ケンブリッジ リミティド 疼痛の治療のためのvap−1阻害剤
CN109810041B (zh) * 2017-11-21 2023-08-15 药捷安康(南京)科技股份有限公司 卤代烯丙基胺类ssao/vap-1抑制剂及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3377345A (en) * 1966-09-23 1968-04-09 Dow Chemical Co Substituted 3, 4, 5, 6-tetrahydro-2h-1, 3, 4-oxadiazin-2-one compounds and method ofpreparation thereof
US3486916A (en) 1966-12-22 1969-12-30 William A Cordon Cement mixes and the production of articles therefrom
SE320311B (fr) 1968-07-15 1970-02-02 Mo Och Domsjoe Ab
EP0639972A1 (fr) * 1992-05-15 1995-03-01 University Of Saskatchewan Procede pour prevenir les lesions de l'endothelium chez les mammiferes et pour soulager la douleur provoquee par la goutte et l'arthrite
US5413634A (en) 1993-08-06 1995-05-09 Arco Chemical Technology, L.P. Cement composition
CA2117585C (fr) 1993-09-14 2001-06-05 Edward T. Shawl Composition de liant
AU2696795A (en) 1994-08-25 1996-03-14 W.R. Grace & Co.-Conn. Shrinkage reduction cement composition
US5618344A (en) 1995-03-06 1997-04-08 W. R. Grace & Co.-Conn. Cement composition
US5603760A (en) 1995-09-18 1997-02-18 W. R. Grace & Co.-Conn. Cement admixture capable of inhibiting drying shrinkage and method of using same
US5556460A (en) 1995-09-18 1996-09-17 W.R. Grace & Co.-Conn. Drying shrinkage cement admixture
AU2001282162A1 (en) 2000-07-05 2002-01-14 Biotie Therapies Corp. Inhibitors of copper-containing amine oxidases

Also Published As

Publication number Publication date
RU2003103291A (ru) 2005-01-27
HUP0301336A3 (en) 2005-04-28
NO20026283L (no) 2003-02-28
WO2002002090A3 (fr) 2002-05-16
HUP0301625A3 (en) 2005-04-28
PL360353A1 (en) 2004-09-06
AU8216301A (en) 2002-01-14
NZ523464A (en) 2003-10-31
CA2414799A1 (fr) 2002-01-10
ZA200300063B (en) 2003-07-22
US6624202B2 (en) 2003-09-23
WO2002002541A3 (fr) 2002-04-18
ZA200300064B (en) 2003-07-22
EP1313718A2 (fr) 2003-05-28
PL360374A1 (en) 2004-09-06
AU2001282162A1 (en) 2002-01-14
US20020173521A1 (en) 2002-11-21
CA2414807A1 (fr) 2002-01-10
JP2004501962A (ja) 2004-01-22
EP1301495A2 (fr) 2003-04-16
IL153767A0 (en) 2003-07-06
HUP0301336A2 (hu) 2003-08-28
US20040106654A1 (en) 2004-06-03
CN1450997A (zh) 2003-10-22
WO2002002090A2 (fr) 2002-01-10
JP2004502682A (ja) 2004-01-29
NO20026283D0 (no) 2002-12-30
CN1450998A (zh) 2003-10-22
AU2001282163B2 (en) 2004-12-09
RU2003103286A (ru) 2004-08-20
NZ523463A (en) 2004-06-25
WO2002002541A2 (fr) 2002-01-10
HUP0301625A2 (hu) 2003-11-28
IL153766A0 (en) 2003-07-06
NO20026282D0 (no) 2002-12-30

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