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NO20025355L - Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII - Google Patents

Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII

Info

Publication number
NO20025355L
NO20025355L NO20025355A NO20025355A NO20025355L NO 20025355 L NO20025355 L NO 20025355L NO 20025355 A NO20025355 A NO 20025355A NO 20025355 A NO20025355 A NO 20025355A NO 20025355 L NO20025355 L NO 20025355L
Authority
NO
Norway
Prior art keywords
factor
pharmaceutical composition
xiii
viia
factor viia
Prior art date
Application number
NO20025355A
Other languages
English (en)
Norwegian (no)
Other versions
NO20025355D0 (no
Inventor
Lars Christian Petersen
Ulla Hedner
Rasmus Roejkjaer
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO20025355D0 publication Critical patent/NO20025355D0/no
Publication of NO20025355L publication Critical patent/NO20025355L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
NO20025355A 2000-05-10 2002-11-08 Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII NO20025355L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200000771 2000-05-10
DKPA200000778 2000-05-10
DKPA200000871 2000-06-06
PCT/DK2001/000322 WO2001085198A1 (en) 2000-05-10 2001-05-10 tHARMACEUTICAL COMPOSITION COMPRISING A FACTOR VIIA AND A FACTOR XIII

Publications (2)

Publication Number Publication Date
NO20025355D0 NO20025355D0 (no) 2002-11-08
NO20025355L true NO20025355L (no) 2003-01-09

Family

ID=27222387

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025355A NO20025355L (no) 2000-05-10 2002-11-08 Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII

Country Status (17)

Country Link
US (3) US20030092627A1 (cs)
EP (3) EP1593389A1 (cs)
JP (2) JP2004505016A (cs)
CN (1) CN1304049C (cs)
AT (2) ATE311198T1 (cs)
AU (3) AU5822801A (cs)
BR (1) BR0110659A (cs)
CA (1) CA2406583A1 (cs)
CZ (1) CZ20023667A3 (cs)
DE (2) DE60115422T2 (cs)
DK (1) DK1282438T3 (cs)
ES (2) ES2254414T3 (cs)
HU (1) HUP0301868A3 (cs)
IL (1) IL152554A0 (cs)
NO (1) NO20025355L (cs)
PL (1) PL365042A1 (cs)
WO (2) WO2001085198A1 (cs)

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EP1319067A2 (en) * 2000-09-13 2003-06-18 Novo Nordisk A/S Human coagulation factor vii variants
US7176288B2 (en) 2000-09-13 2007-02-13 Novo Nordisk Healthcare A/G Human coagulation factor VII variants
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EP1351706B1 (en) * 2000-11-10 2007-07-25 ZymoGenetics, Inc. Factor xiii in combination with factor ix for treating hemophilia b
WO2002062377A2 (en) * 2001-02-05 2002-08-15 Novo Nordisk Health Care Ag Combined use of factor vii polypeptides and factor viii polypeptides
CA2438761A1 (en) * 2001-02-21 2002-09-06 Zymogenetics, Inc. Method for treating von willebrand's disease
IL160703A0 (en) * 2001-09-10 2004-08-31 Zymogenetics Inc Method for treating coumarin-induced hemorrhage
US7052868B2 (en) 2001-09-27 2006-05-30 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
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US6911323B2 (en) 2002-09-25 2005-06-28 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
ATE424215T1 (de) 2003-01-08 2009-03-15 Novartis Vaccines & Diagnostic Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante
ATE547114T1 (de) 2003-06-25 2012-03-15 Novo Nordisk Healthcare Ag Flüssige zusammensetzungen von factor vii polypeptiden
CA2534028A1 (en) 2003-08-14 2005-02-24 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of factor vii polypeptides
CN1863908B (zh) 2003-09-09 2010-08-04 诺和诺德医疗保健公司 凝固因子ⅶ多肽
WO2005107795A1 (en) * 2004-05-11 2005-11-17 Novo Nordisk Health Care Ag Use of factor viia for the treatment of burn traumas
WO2005115442A1 (en) * 2004-05-25 2005-12-08 Novo Nordisk Health Care Ag Use of coagulation factor xiii for treatment of post surgical bleedings
WO2006021584A2 (en) * 2004-08-27 2006-03-02 Novo Nordisk Health Care Ag Purification of factor xiii polypeptides from biological materials
BRPI0515163A (pt) * 2004-09-10 2008-07-08 Pharmaorigin Aps métodos para tratar hemoptise ou sangramento traqueal, brÈnquico ou alveolar local
JP5086093B2 (ja) 2004-11-23 2012-11-28 ジモジェネティクス、インコーポレイテッド 組換え型ヒトｘｉｉｉ因子の精製
JP5236952B2 (ja) * 2005-02-28 2013-07-17 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 改善された特性を有するｆｘｉｉｉバリアント
EP1919499A2 (en) * 2005-07-29 2008-05-14 Universiteit van Maastricht Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor
EP2004214B1 (en) * 2006-03-16 2012-11-07 STELLARIS PHARMACEUTICALS Aps Local treatment with factor vii
WO2008009635A2 (en) * 2006-07-17 2008-01-24 Novo Nordisk Health Care Ag Factor viia analogues with increased activity for treating thrombocytopenia
NZ579985A (en) * 2007-04-13 2012-02-24 Catalyst Biosciences Inc Modified factor vii polypetides and uses thereof
TWI538916B (zh) 2008-04-11 2016-06-21 介控生化科技公司 經修飾的因子vii多肽和其用途
WO2009130181A2 (en) 2008-04-21 2009-10-29 Novo Nordisk Health Care Ag Dry transglutaminase composition
EP2149603A1 (en) 2008-07-28 2010-02-03 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Factor IX variants with clotting activity in absence of their cofactor and their use for treating bleeding disorders
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
BRPI0922344A2 (pt) * 2008-12-19 2017-10-24 3B Pharmaceuticals Gmbh inibidores de tfpi e métodos de uso
WO2011115712A2 (en) 2010-03-19 2011-09-22 Baxter International Inc Tfpi inhibitors and methods of use
AR082588A1 (es) * 2010-08-05 2012-12-19 Council Scient Ind Res Construcciones de proteinas de fusion con propiedades tromboliticas y anticoagulantes
CN104302306B (zh) 2012-03-21 2019-03-22 百深有限责任公司 Tfpi抑制剂及其使用方法
EP2881463A1 (en) 2013-12-09 2015-06-10 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Factor IX variants with clotting activity in absence of their cofactor and/or with increased F.IX clotting activity and their use for treating bleeding disorders
JP6559188B2 (ja) * 2017-07-06 2019-08-14 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP2018038398A (ja) * 2017-09-04 2018-03-15 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP2018108089A (ja) * 2018-02-19 2018-07-12 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
WO2020021890A1 (ja) * 2018-07-25 2020-01-30 ソニー株式会社 血液凝固系解析装置
JP6848016B2 (ja) * 2019-07-16 2021-03-24 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
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US20030119723A1 (en) * 2001-11-09 2003-06-26 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and PAI-1 polypeptides
US7078479B2 (en) * 2001-11-09 2006-07-18 Novo Nordisk Healthcare A/G Pharmaceutical composition comprising factor VII polypeptides and alpha2-antiplasmin polypeptides

Also Published As

Publication number Publication date
EP1282439A1 (en) 2003-02-12
US20070280920A1 (en) 2007-12-06
NO20025355D0 (no) 2002-11-08
US20060199766A1 (en) 2006-09-07
EP1282439B1 (en) 2005-11-30
CN1304049C (zh) 2007-03-14
ATE300953T1 (de) 2005-08-15
IL152554A0 (en) 2003-05-29
HUP0301868A2 (hu) 2003-08-28
WO2001085198A1 (en) 2001-11-15
CZ20023667A3 (cs) 2003-04-16
ATE311198T1 (de) 2005-12-15
WO2001085199A1 (en) 2001-11-15
DE60115422T2 (de) 2006-08-17
JP2003532684A (ja) 2003-11-05
EP1593389A1 (en) 2005-11-09
PL365042A1 (en) 2004-12-27
DE60115422D1 (de) 2006-01-05
ES2247106T3 (es) 2006-03-01
AU2001258230A1 (en) 2001-11-20
DE60112429T2 (de) 2006-06-01
CN1429117A (zh) 2003-07-09
DK1282438T3 (da) 2005-11-14
ES2254414T3 (es) 2006-06-16
BR0110659A (pt) 2003-02-11
HUP0301868A3 (en) 2006-11-28
EP1282438A1 (en) 2003-02-12
AU2001258228B2 (en) 2006-01-12
CA2406583A1 (en) 2001-11-15
EP1282438B1 (en) 2005-08-03
US20030092627A1 (en) 2003-05-15
AU5822801A (en) 2001-11-20
JP2004505016A (ja) 2004-02-19
DE60112429D1 (de) 2005-09-08

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