NO20025810L - Factor VIIA inhibitory (ten) urea derivatives, their preparation and use - Google Patents

Factor VIIA inhibitory (ten) urea derivatives, their preparation and use

Info

Publication number: NO20025810L
Authority: NO; Norway
Prior art keywords: preparation; factor viia; urea derivatives; viia inhibitory; inhibitory
Prior art date: 2000-06-06

Application number

NO20025810A

Other languages

Norwegian (no)

Other versions

NO20025810D0 (en

NO328546B1 (en

Inventor

Otmar Klingler

Manfred Schudok

Hans-Peter Nestler

Hans Matter

Herman Schreuder

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-06

Filing date

2002-12-03

Publication date

2002-12-03

2002-12-03 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2002-12-03 Publication of NO20025810D0 publication Critical patent/NO20025810D0/en

2002-12-03 Publication of NO20025810L publication Critical patent/NO20025810L/en

2010-03-15 Publication of NO328546B1 publication Critical patent/NO328546B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Diabetes (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Thiazole And Isothizaole Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO20025810A 2000-06-06 2002-12-03 Factor VIIA inhibitory (ten) urea derivatives, their preparation and pharmaceutical compositions comprising such. NO328546B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00112116A EP1162194A1 (en)	2000-06-06	2000-06-06	Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
PCT/EP2001/006029 WO2001094301A2 (en)	2000-06-06	2001-05-26	Factor viia inhibitory (thio)urea derivatives, their preparation and their use

Publications (3)

Publication Number	Publication Date
NO20025810D0 NO20025810D0 (en)	2002-12-03
NO20025810L true NO20025810L (en)	2002-12-03
NO328546B1 NO328546B1 (en)	2010-03-15

Family

ID=8168926

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20025810A NO328546B1 (en)	2000-06-06	2002-12-03	Factor VIIA inhibitory (ten) urea derivatives, their preparation and pharmaceutical compositions comprising such.

Country Status (29)

Country	Link
US (1)	US6743790B2 (en)
EP (2)	EP1162194A1 (en)
JP (1)	JP4809570B2 (en)
KR (1)	KR101011345B1 (en)
CN (1)	CN1208314C (en)
AR (1)	AR030936A1 (en)
AU (2)	AU2001277494B2 (en)
BR (1)	BR0111264A (en)
CA (1)	CA2410862C (en)
CZ (1)	CZ20023963A3 (en)
DE (1)	DE60139320D1 (en)
DK (1)	DK1299354T3 (en)
EE (1)	EE200200617A (en)
ES (1)	ES2330412T3 (en)
HR (1)	HRP20020961A2 (en)
HU (1)	HUP0301631A2 (en)
IL (2)	IL153220A0 (en)
MX (1)	MXPA02009789A (en)
MY (1)	MY129363A (en)
NO (1)	NO328546B1 (en)
NZ (1)	NZ522960A (en)
PL (1)	PL359584A1 (en)
PT (1)	PT1299354E (en)
RU (1)	RU2286337C2 (en)
SK (1)	SK17032002A3 (en)
TW (1)	TWI283662B (en)
WO (1)	WO2001094301A2 (en)
YU (1)	YU89202A (en)
ZA (1)	ZA200209018B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003226755A1 (en) *	2002-04-27	2003-11-17	Merck Patent Gmbh	Carboxylic acid amides
PL374971A1 (en) *	2002-08-09	2005-11-14	Transtech Pharma, Inc.	Aryl and heteroaryl compounds and methods to modulate coagulation
CA2525854C (en) *	2003-05-20	2009-12-15	Genentech, Inc.	Acylsulfamide inhibitors of factor viia
WO2004113316A1 (en) *	2003-05-20	2004-12-29	Genentech, Inc.	Benzofuran inhibitors of factor viia
CN1832920A (en) *	2003-08-08	2006-09-13	特兰斯泰克制药公司	Aryl and heteroaryl compounds, compositions, and methods of use
WO2005014532A1 (en) *	2003-08-08	2005-02-17	Transtech Pharma, Inc.	Aryl and heteroaryl compounds, compositions and methods of use
US7208601B2 (en) *	2003-08-08	2007-04-24	Mjalli Adnan M M	Aryl and heteroaryl compounds, compositions, and methods of use
EP1810965A4 (en) *	2004-10-13	2009-10-28	Eisai R&D Man Co Ltd	Hydrazide derivatives
TW200630337A (en) *	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
JP2008531525A (en) *	2005-02-24	2008-08-14	ノボノルディスクヘルスケアアクチェンゲゼルシャフト	Compounds that stabilize factor VII polypeptide formulations
JP2008531524A (en) *	2005-02-24	2008-08-14	ノボノルディスクヘルスケアアクチェンゲゼルシャフト	Compounds that stabilize factor VII polypeptide formulations
US20090130085A1 (en) *	2005-02-24	2009-05-21	Novo Nordish Healthcare Ag	Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations
WO2006134173A2 (en)	2005-06-17	2006-12-21	Novo Nordisk Health Care Ag	Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
HRP20110054T1 (en)	2006-03-24	2011-02-28	Eisai R&D Management Co.	DERIVAT TRIAZOLONA
WO2007110449A1 (en) *	2006-03-29	2007-10-04	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use
US8791264B2 (en) *	2006-04-13	2014-07-29	Purdue Pharma L.P.	Benzenesulfonamide compounds and their use as blockers of calcium channels
TW200812963A (en) *	2006-04-13	2008-03-16	Euro Celtique Sa	Benzenesulfonamide compounds and the use thereof
WO2008124118A1 (en) *	2007-04-09	2008-10-16	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use therof
JPWO2009038157A1 (en)	2007-09-21	2011-01-06	エーザイ・アール・アンド・ディー・マネジメント株式会社	2,3-dihydro-iminoisoindole derivatives
US8765736B2 (en) *	2007-09-28	2014-07-01	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
UA115043C2 (en)	2011-10-26	2017-09-11	Аллерган, Інк.	N-CARBAMIDE-SUBSTITUTED AMINO ACID AMYDIDES AS MODULES OF FORMILPEPTIDE RECEPTOR 1 (FPRL-1)
KR20140145203A (en) *	2012-04-16	2014-12-22	알러간, 인코포레이티드	(2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
EP2906236A1 (en) *	2012-10-10	2015-08-19	Novo Nordisk Health Care AG	Liquid pharmaceutical composition of factor vii polypeptide
CN105007909B (en)	2013-03-06	2019-06-28	阿勒根公司	Use of formyl peptide receptor 2 agonists for the treatment of ocular inflammatory diseases
RU2696487C2 (en)	2013-03-06	2019-08-02	Аллерган, Инк.	Using formylpeptide receptor 2 agonists for treating dermatologic diseases

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5273982A (en) *	1990-03-09	1993-12-28	Hoffmann-La Roche Inc.	Acetic acid derivatives
US5506134A (en)	1990-10-22	1996-04-09	Corvas International, Inc.	Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
WO1992013552A1 (en) *	1991-02-05	1992-08-20	Smithkline Beecham Corporation	Anti-aggregatory peptides containing an aromatic ester or amide
US5788965A (en)	1991-02-28	1998-08-04	Novo Nordisk A/S	Modified factor VII
US5833982A (en)	1991-02-28	1998-11-10	Zymogenetics, Inc.	Modified factor VII
JP3387948B2 (en) *	1992-12-04	2003-03-17	富山化学工業株式会社	Novel phenylalanine derivative or salt thereof
US5314902A (en) *	1993-01-27	1994-05-24	Monsanto Company	Urea derivatives useful as platelet aggregation inhibitors
DE4309867A1 (en) *	1993-03-26	1994-09-29	Cassella Ag	New urea derivatives, their production and use
GB9313268D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Chemical compounds
GB9313269D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Allophanic acid derivatives
WO1995008550A1 (en) *	1993-09-24	1995-03-30	Abbott Laboratories	Endothelin antagonists
ATE198739T1 (en) *	1993-10-19	2001-02-15	Sumitomo Pharma	2,3-DIAMINOPROPIONIC ACID DERIVATIVES
US5674894A (en) *	1995-05-15	1997-10-07	G.D. Searle & Co.	Amidine derivatives useful as platelet aggregation inhibitors and vasodilators
AU712504B2 (en) *	1996-01-30	1999-11-11	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
ID24475A (en) *	1997-11-18	2000-07-20	Teijin Limeted Cs	AMINIC CYCLICS AND ITS USE AS DRUGS
EP0987274A1 (en) *	1998-09-15	2000-03-22	Hoechst Marion Roussel Deutschland GmbH	Factor VIIa Inhibitors

2000
- 2000-06-06 EP EP00112116A patent/EP1162194A1/en not_active Withdrawn
2001
- 2001-05-26 BR BR0111264-3A patent/BR0111264A/en not_active IP Right Cessation
- 2001-05-26 HU HU0301631A patent/HUP0301631A2/en unknown
- 2001-05-26 SK SK1703-2002A patent/SK17032002A3/en not_active Application Discontinuation
- 2001-05-26 AU AU2001277494A patent/AU2001277494B2/en not_active Ceased
- 2001-05-26 DK DK01955291T patent/DK1299354T3/en active
- 2001-05-26 IL IL15322001A patent/IL153220A0/en unknown
- 2001-05-26 EP EP01955291A patent/EP1299354B1/en not_active Expired - Lifetime
- 2001-05-26 CA CA002410862A patent/CA2410862C/en not_active Expired - Fee Related
- 2001-05-26 PT PT01955291T patent/PT1299354E/en unknown
- 2001-05-26 AU AU7749401A patent/AU7749401A/en active Pending
- 2001-05-26 CZ CZ20023963A patent/CZ20023963A3/en unknown
- 2001-05-26 EE EEP200200617A patent/EE200200617A/en unknown
- 2001-05-26 DE DE60139320T patent/DE60139320D1/en not_active Expired - Lifetime
- 2001-05-26 MX MXPA02009789A patent/MXPA02009789A/en active IP Right Grant
- 2001-05-26 KR KR1020027016691A patent/KR101011345B1/en not_active Expired - Fee Related
- 2001-05-26 RU RU2002135308/04A patent/RU2286337C2/en not_active IP Right Cessation
- 2001-05-26 WO PCT/EP2001/006029 patent/WO2001094301A2/en not_active Ceased
- 2001-05-26 PL PL01359584A patent/PL359584A1/en not_active Application Discontinuation
- 2001-05-26 CN CNB018088309A patent/CN1208314C/en not_active Expired - Fee Related
- 2001-05-26 HR HRP20020961 patent/HRP20020961A2/en not_active Application Discontinuation
- 2001-05-26 JP JP2002501818A patent/JP4809570B2/en not_active Expired - Fee Related
- 2001-05-26 NZ NZ522960A patent/NZ522960A/en unknown
- 2001-05-26 YU YU89202A patent/YU89202A/en unknown
- 2001-05-26 ES ES01955291T patent/ES2330412T3/en not_active Expired - Lifetime
- 2001-06-04 AR ARP010102657A patent/AR030936A1/en active IP Right Grant
- 2001-06-04 TW TW090113412A patent/TWI283662B/en not_active IP Right Cessation
- 2001-06-05 MY MYPI20012631A patent/MY129363A/en unknown
- 2001-06-06 US US09/874,318 patent/US6743790B2/en not_active Expired - Lifetime
2002
- 2002-11-06 ZA ZA200209018A patent/ZA200209018B/en unknown
- 2002-12-02 IL IL153220A patent/IL153220A/en not_active IP Right Cessation
- 2002-12-03 NO NO20025810A patent/NO328546B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ522960A (en)	2004-05-28
US6743790B2 (en)	2004-06-01
HUP0301631A2 (en)	2003-09-29
KR20030007911A (en)	2003-01-23
EE200200617A (en)	2004-04-15
NO20025810D0 (en)	2002-12-03
HK1055941A1 (en)	2004-01-30
YU89202A (en)	2006-05-25
BR0111264A (en)	2003-06-17
WO2001094301A3 (en)	2002-04-04
PT1299354E (en)	2009-10-01
US20020052417A1 (en)	2002-05-02
KR101011345B1 (en)	2011-01-28
HRP20020961A2 (en)	2004-12-31
IL153220A (en)	2008-11-03
EP1299354A2 (en)	2003-04-09
CN1208314C (en)	2005-06-29
EP1162194A1 (en)	2001-12-12
NO328546B1 (en)	2010-03-15
ES2330412T3 (en)	2009-12-10
DE60139320D1 (en)	2009-09-03
DK1299354T3 (en)	2009-11-16
PL359584A1 (en)	2004-08-23
RU2286337C2 (en)	2006-10-27
CA2410862C (en)	2009-11-10
CN1427818A (en)	2003-07-02
MY129363A (en)	2007-03-30
SK17032002A3 (en)	2003-05-02
MXPA02009789A (en)	2003-03-12
EP1299354B1 (en)	2009-07-22
CA2410862A1 (en)	2001-12-13
ZA200209018B (en)	2003-10-08
JP2003535844A (en)	2003-12-02
WO2001094301A2 (en)	2001-12-13
IL153220A0 (en)	2003-07-06
AU7749401A (en)	2001-12-17
AU2001277494B2 (en)	2006-05-04
TWI283662B (en)	2007-07-11
AR030936A1 (en)	2003-09-03
CZ20023963A3 (en)	2003-03-12
JP4809570B2 (en)	2011-11-09

Publication	Publication Date	Title
NO20025810L (en)	2002-12-03	Factor VIIA inhibitory (ten) urea derivatives, their preparation and use
DK1368349T3 (en)	2007-05-21	Xanthine derivatives, their preparation and their use as pharmaceuticals
NO20024742L (en)	2002-11-25	Heterocyclic compounds, their preparation and use
NO20015362L (en)	2001-11-02	Heterocyclic substituted benzimidazoles, their preparation and use thereof
NO20021449L (en)	2002-05-07	Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use
NO20015156L (en)	2001-12-18	5-pyridyl-1,3-azole compounds, their preparation and use
NO20014603L (en)	2001-11-26	Tienopyrimidine Compounds, Their Preparation and Use
NO20015113D0 (en)	2001-10-19	New compounds, their preparation and use
NO20012567D0 (en)	2001-05-25	Azepinoindole derivatives, preparation and use thereof
DK1455785T3 (en)	2009-06-08	Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and their use
NO20042635L (en)	2004-06-23	5-Sulfanyl-HH-1,2,4-triazole derivatives and their use as medicine
NO20030596D0 (en)	2003-02-06	Benzimidazole derivatives, their preparation and therapeutic use
DK1095025T3 (en)	2003-04-07	Benzimidazoles, their preparation and their use as drugs
EE200300311A (en)	2003-10-15	Phthalazinone-piperidine derivatives, their use and medicine
NO20025357D0 (en)	2002-11-08	Anthranylamides and their use as drugs
NO20031838D0 (en)	2003-04-24	Benzocazine derivatives, their preparation and use
DK1161434T3 (en)	2003-05-26	Pyridopyranoazepine derivatives, their preparation and therapeutic use
NO20023146L (en)	2002-06-28	Substituted phenyl-piperazine derivatives, their preparation and use
DK1043307T3 (en)	2003-09-22	3-Amino-3-arylpropan-1-ol derivatives, their preparation and use
DK1345900T3 (en)	2007-05-21	Guanidine and amidine derivatives as factor XA inhibitors
NO20032234D0 (en)	2003-05-16	Novel imidazole derivatives, their preparation and use
NO20024107L (en)	2002-09-27	Tienopyridine derivatives, their preparation and use
NO20025209L (en)	2002-10-30	Cyclipostins, their preparation and use
NO20001782D0 (en)	2000-04-06	3-Amino-3-arylpropan-1-ol derivatives, their preparation and use
DK1200409T3 (en)	2004-06-28	Substituted isoquinoline derivatives and their use as anticonvulsants

Legal Events

Date	Code	Title	Description
2013-12-23	MM1K	Lapsed by not paying the annual fees