NO20025720L - Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitet - Google Patents
Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitetInfo
- Publication number
- NO20025720L NO20025720L NO20025720A NO20025720A NO20025720L NO 20025720 L NO20025720 L NO 20025720L NO 20025720 A NO20025720 A NO 20025720A NO 20025720 A NO20025720 A NO 20025720A NO 20025720 L NO20025720 L NO 20025720L
- Authority
- NO
- Norway
- Prior art keywords
- antifungal
- antibacterial
- antitumor activity
- new compounds
- antitumor
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21447800P | 2000-06-27 | 2000-06-27 | |
| PCT/US2001/020334 WO2002000650A2 (fr) | 2000-06-27 | 2001-06-26 | Nouveaux composes possedant une activite anti-bacterienne, antifongique et anti-tumeur |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20025720D0 NO20025720D0 (no) | 2002-11-28 |
| NO20025720L true NO20025720L (no) | 2003-02-26 |
Family
ID=22799223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20025720A NO20025720L (no) | 2000-06-27 | 2002-11-28 | Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitet |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6849713B2 (fr) |
| EP (1) | EP1294713A2 (fr) |
| JP (1) | JP2004501915A (fr) |
| KR (1) | KR20030011371A (fr) |
| CN (1) | CN1439006A (fr) |
| AU (1) | AU2001270183A1 (fr) |
| BR (1) | BR0112030A (fr) |
| CA (1) | CA2414512A1 (fr) |
| IL (1) | IL153119A0 (fr) |
| MX (1) | MXPA02012271A (fr) |
| NO (1) | NO20025720L (fr) |
| NZ (1) | NZ522839A (fr) |
| RU (1) | RU2003101969A (fr) |
| WO (1) | WO2002000650A2 (fr) |
| ZA (1) | ZA200209774B (fr) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7122626B2 (en) | 2001-04-26 | 2006-10-17 | Genesoft Pharmceuticals, Inc. | Halogen-substitued thienyl compounds |
| US6825228B2 (en) | 2001-06-13 | 2004-11-30 | Genesoft Pharmaceuticals, Inc. | Benzothiophene compounds having antiinfective activity |
| US20030236198A1 (en) | 2001-06-13 | 2003-12-25 | Genesoft, Inc. | Antipathogenic benzamide compounds |
| ITTO20010633A1 (it) * | 2001-07-02 | 2003-01-02 | Univ Ferrara | Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a. |
| GB0130868D0 (en) | 2001-12-24 | 2002-02-06 | Univ Strathclyde | New compounds |
| AU2002364209A1 (en) * | 2001-12-26 | 2003-07-24 | Genelabs Technologies, Inc. | Polyamide derivatives possessing antibacterial, antifungal or antitumor activity |
| ITMI20021455A1 (it) * | 2002-07-02 | 2004-01-02 | Ugo Raffaello Citernesi | Formulazioni fosfolipidiche di lexitropsine loro preparazione ed impiego terapeutico |
| US7498349B2 (en) | 2002-08-02 | 2009-03-03 | Genesoft Pharmaceuticals, Inc. | Biaryl compounds having anti-infective activity |
| EP1556035A4 (fr) * | 2002-09-20 | 2006-09-13 | Genelabs Tech Inc | Nouveaux composes aromatiques possedant une activite antifongique ou antibacterienne |
| WO2004035571A1 (fr) * | 2002-10-15 | 2004-04-29 | Rigel Pharmaceuticals, Inc. | Indoles substitues et leur utilisation en tant qu'inhibiteurs du virus de l'hepatite c (vhc) |
| WO2004039318A2 (fr) | 2002-10-25 | 2004-05-13 | Genesoft Pharmaceuticals, Inc. | Composes biaryle anti-infectieux |
| EP1587529A4 (fr) | 2002-12-10 | 2009-08-12 | Oscient Pharmaceuticals Corp | Composes antibacteriens possedant un motif (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) |
| US20050032868A1 (en) * | 2003-05-02 | 2005-02-10 | Garofalo Albert W. | Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists |
| CA2524274A1 (fr) * | 2003-05-02 | 2004-11-18 | Elan Pharmaceuticals, Inc. | Derives amide 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-acide carboxylique (1-(aminocarbonyl)eth-1-yl) et composes correspondants tels qu e les antagonistes du recepteur de la bradykinine de type b1 pour le traitement des maladies inflammatoires |
| PE20050525A1 (es) * | 2003-05-02 | 2005-09-08 | Elan Pharm Inc | Derivados de pirazol sustituido y compuestos relacionados como antagonistas del receptor de bradiquinina b1 |
| EP1831225A2 (fr) * | 2004-11-19 | 2007-09-12 | The Regents of the University of California | Pyrazolopyrimidines anti-inflammatoires |
| KR20120051760A (ko) | 2006-04-04 | 2012-05-22 | 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 | 키나제 길항물질 |
| AU2007294149A1 (en) * | 2006-09-06 | 2008-03-13 | F. Hoffmann-La Roche Ag | Heteroaryl derivatives as protein kinase inhibitors |
| GB0619325D0 (en) | 2006-09-30 | 2006-11-08 | Univ Strathclyde | New compounds |
| GB2467670B (en) | 2007-10-04 | 2012-08-01 | Intellikine Inc | Chemical entities and therapeutic uses thereof |
| JP5869222B2 (ja) * | 2008-01-04 | 2016-02-24 | インテリカイン， エルエルシー | 特定の化学的実体、組成物および方法 |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| WO2009114870A2 (fr) * | 2008-03-14 | 2009-09-17 | Intellikine, Inc. | Inhibiteurs de kinases, et procédés d’utilisation associés |
| WO2009114874A2 (fr) | 2008-03-14 | 2009-09-17 | Intellikine, Inc. | Inhibiteurs de kinases (benzothiazole) et procédés d’utilisation associés |
| WO2010006086A2 (fr) | 2008-07-08 | 2010-01-14 | Intellikine, Inc. | Inhibiteurs de kinases et procédés d'utilisation |
| WO2010006072A2 (fr) | 2008-07-08 | 2010-01-14 | The Regents Of The University Of California | Modulateurs de mtor et leurs utilisations |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| EP2346508B1 (fr) | 2008-09-26 | 2016-08-24 | Intellikine, LLC | Inhibiteurs hétérocycliques de kinases |
| AU2009305669A1 (en) | 2008-10-16 | 2010-04-22 | The Regents Of The University Of California | Fused ring heteroaryl kinase inhibitors |
| US8476431B2 (en) | 2008-11-03 | 2013-07-02 | Itellikine LLC | Benzoxazole kinase inhibitors and methods of use |
| JP5789252B2 (ja) | 2009-05-07 | 2015-10-07 | インテリカイン， エルエルシー | 複素環式化合物およびその使用 |
| US8980899B2 (en) | 2009-10-16 | 2015-03-17 | The Regents Of The University Of California | Methods of inhibiting Ire1 |
| EP2571357B1 (fr) | 2010-05-21 | 2016-07-06 | Infinity Pharmaceuticals, Inc. | Composés chimiques, compositions et procédés pour modulation de kinases |
| CA2817577A1 (fr) | 2010-11-10 | 2012-05-18 | Infinity Pharmaceuticals, Inc. | Composes heterocycliques et utilisations de ceux-ci |
| SG10201600179RA (en) | 2011-01-10 | 2016-02-26 | Infinity Pharmaceuticals Inc | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
| CN103491962B (zh) | 2011-02-23 | 2016-10-12 | 因特利凯有限责任公司 | 激酶抑制剂的组合及其用途 |
| MX2014000648A (es) | 2011-07-19 | 2014-09-25 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y sus usos. |
| EP2734520B1 (fr) | 2011-07-19 | 2016-09-14 | Infinity Pharmaceuticals, Inc. | Composés hétérocycliques et leurs utilisations |
| CN102952062B (zh) * | 2011-08-12 | 2016-06-08 | 中国医学科学院医药生物技术研究所 | 取代苯并杂环类化合物及其制备方法和应用 |
| KR20140075693A (ko) | 2011-08-29 | 2014-06-19 | 인피니티 파마슈티칼스, 인코포레이티드 | 헤테로사이클릭 화합물 및 그의 용도 |
| MX370814B (es) | 2011-09-02 | 2020-01-08 | Univ California | Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas. |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| US8921426B2 (en) | 2012-04-18 | 2014-12-30 | International Business Machines Corporation | Cationic bis-urea compounds as effective antimicrobial agents |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| SG11201502331RA (en) | 2012-09-26 | 2015-04-29 | Univ California | Modulation of ire1 |
| HUE040126T2 (hu) | 2012-11-01 | 2019-02-28 | Infinity Pharmaceuticals Inc | Rákok kezelése PI3 kináz izoform modulátorok alkalmazásával |
| US9481667B2 (en) | 2013-03-15 | 2016-11-01 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| WO2015051241A1 (fr) | 2013-10-04 | 2015-04-09 | Infinity Pharmaceuticals, Inc. | Composés hétérocycliques et leurs utilisations |
| MX389256B (es) | 2013-10-04 | 2025-03-20 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y usos de los mismos. |
| WO2015143012A1 (fr) | 2014-03-19 | 2015-09-24 | Infinity Pharmaceuticals, Inc. | Composés hétérocycliques destinés à être utilisés dans le traitement de troubles médiés par pi3k-gamma |
| WO2015160975A2 (fr) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Polythérapies |
| WO2016054491A1 (fr) | 2014-10-03 | 2016-04-07 | Infinity Pharmaceuticals, Inc. | Composés hétérocycliques et leurs utilisations |
| CN104845967B (zh) | 2015-04-15 | 2020-12-11 | 苏州新海生物科技股份有限公司 | 寡聚核苷酸片段及使用其的选择性扩增目标核酸序列变异体的方法及应用 |
| US10800732B2 (en) * | 2015-08-17 | 2020-10-13 | National Taiwan University | Substituted malonamides and their use as antibacterial drugs |
| EP4585268A3 (fr) | 2015-09-14 | 2025-10-15 | Twelve Therapeutics, Inc. | Formes solides de dérivés d'isoquinolinone, procédé de fabrication, compositions comprenant celles-ci et leurs procédés d'utilisation |
| WO2017161116A1 (fr) | 2016-03-17 | 2017-09-21 | Infinity Pharmaceuticals, Inc. | Isotopologues de composés isoquinolinone et quinazolinone et leurs utilisations comme inhibiteurs de la kinase pi3k |
| US10919914B2 (en) | 2016-06-08 | 2021-02-16 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| UA125216C2 (uk) | 2016-06-24 | 2022-02-02 | Інфініті Фармасьютікалз, Інк. | Комбінована терапія |
| WO2018047148A1 (fr) | 2016-09-12 | 2018-03-15 | Novartis Ag | Composés pour inhibition du miarn |
| CN106832175B (zh) * | 2017-02-17 | 2019-10-18 | 华南理工大学 | 一种基于咔唑衍生物的双羟基荧光扩链剂及其制备与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107288A (en) | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| CA1308516C (fr) | 1987-07-06 | 1992-10-06 | J. William Lown | Agents antiviraux et anticancereux oligopeptidiques |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| ES2179831T3 (es) | 1992-09-29 | 2003-02-01 | Inhale Therapeutic Syst | Liberacion en los pulmones de fragmentos activos de hormona paratiroidiana. |
| WO1995004732A1 (fr) | 1993-08-06 | 1995-02-16 | Synphar Laboratories, Inc. | Agents antiretroviraux oligopeptidiques |
| US5502068A (en) | 1995-01-31 | 1996-03-26 | Synphar Laboratories, Inc. | Cyclopropylpyrroloindole-oligopeptide anticancer agents |
-
2001
- 2001-06-26 AU AU2001270183A patent/AU2001270183A1/en not_active Abandoned
- 2001-06-26 CN CN01811885A patent/CN1439006A/zh active Pending
- 2001-06-26 RU RU2003101969/04A patent/RU2003101969A/ru not_active Application Discontinuation
- 2001-06-26 CA CA002414512A patent/CA2414512A1/fr not_active Abandoned
- 2001-06-26 MX MXPA02012271A patent/MXPA02012271A/es unknown
- 2001-06-26 JP JP2002505774A patent/JP2004501915A/ja not_active Withdrawn
- 2001-06-26 NZ NZ522839A patent/NZ522839A/en unknown
- 2001-06-26 US US09/892,327 patent/US6849713B2/en not_active Expired - Fee Related
- 2001-06-26 EP EP01948740A patent/EP1294713A2/fr not_active Withdrawn
- 2001-06-26 IL IL15311901A patent/IL153119A0/xx unknown
- 2001-06-26 KR KR1020027017685A patent/KR20030011371A/ko not_active Withdrawn
- 2001-06-26 BR BR0112030-1A patent/BR0112030A/pt not_active IP Right Cessation
- 2001-06-26 WO PCT/US2001/020334 patent/WO2002000650A2/fr not_active Ceased
-
2002
- 2002-10-23 US US10/277,666 patent/US6906103B2/en not_active Expired - Fee Related
- 2002-11-28 NO NO20025720A patent/NO20025720L/no not_active Application Discontinuation
- 2002-12-02 ZA ZA200209774A patent/ZA200209774B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20020037856A1 (en) | 2002-03-28 |
| ZA200209774B (en) | 2004-03-02 |
| EP1294713A2 (fr) | 2003-03-26 |
| NO20025720D0 (no) | 2002-11-28 |
| IL153119A0 (en) | 2003-06-24 |
| BR0112030A (pt) | 2003-04-29 |
| US20030119749A1 (en) | 2003-06-26 |
| CN1439006A (zh) | 2003-08-27 |
| KR20030011371A (ko) | 2003-02-07 |
| MXPA02012271A (es) | 2004-09-06 |
| WO2002000650A2 (fr) | 2002-01-03 |
| RU2003101969A (ru) | 2004-07-10 |
| US6906103B2 (en) | 2005-06-14 |
| US6849713B2 (en) | 2005-02-01 |
| WO2002000650A9 (fr) | 2003-03-06 |
| WO2002000650A3 (fr) | 2002-10-24 |
| AU2001270183A1 (en) | 2002-01-08 |
| CA2414512A1 (fr) | 2002-01-03 |
| NZ522839A (en) | 2004-11-26 |
| JP2004501915A (ja) | 2004-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |