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NO20021382L - Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser - Google Patents

Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser

Info

Publication number
NO20021382L
NO20021382L NO20021382A NO20021382A NO20021382L NO 20021382 L NO20021382 L NO 20021382L NO 20021382 A NO20021382 A NO 20021382A NO 20021382 A NO20021382 A NO 20021382A NO 20021382 L NO20021382 L NO 20021382L
Authority
NO
Norway
Prior art keywords
panto
microorganisms
compounds
preparation
methods
Prior art date
Application number
NO20021382A
Other languages
English (en)
Norwegian (no)
Other versions
NO20021382D0 (no
Inventor
R Rogers Yocum
Thomas A Patterson
Theron Hermann
Janice G Pero
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO20021382D0 publication Critical patent/NO20021382D0/no
Publication of NO20021382L publication Critical patent/NO20021382L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20021382A 1999-09-21 2002-03-20 Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser NO20021382L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40049499A 1999-09-21 1999-09-21
US21007200P 2000-06-07 2000-06-07
US22183600P 2000-07-28 2000-07-28
US22786000P 2000-08-24 2000-08-24
PCT/US2000/025993 WO2001021772A2 (fr) 1999-09-21 2000-09-21 Procedes et micro-organismes de production de composes panto

Publications (2)

Publication Number Publication Date
NO20021382D0 NO20021382D0 (no) 2002-03-20
NO20021382L true NO20021382L (no) 2002-05-16

Family

ID=27498789

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021382A NO20021382L (no) 1999-09-21 2002-03-20 Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser

Country Status (16)

Country Link
EP (2) EP2163629B1 (fr)
JP (1) JP5392957B2 (fr)
KR (1) KR20020092912A (fr)
CN (1) CN1420931A (fr)
AU (1) AU7708700A (fr)
BR (1) BRPI0014115B8 (fr)
CA (1) CA2385497A1 (fr)
CZ (1) CZ20021013A3 (fr)
HU (1) HU230509B1 (fr)
IL (1) IL148786A0 (fr)
MX (1) MXPA02003017A (fr)
NO (1) NO20021382L (fr)
PL (1) PL356566A1 (fr)
SK (1) SK5222002A3 (fr)
TR (1) TR200200751T2 (fr)
WO (1) WO2001021772A2 (fr)

Families Citing this family (60)

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US6830898B2 (en) 2000-08-24 2004-12-14 Omnigene Bioproducts, Inc. Microorganisms and assays for the identification of antibiotics
DE10101501A1 (de) * 2001-01-12 2002-08-01 Forschungszentrum Juelich Gmbh Verfahren zur fermentativen Herstellung von Pantothensäure
EE200300343A (et) * 2001-01-19 2003-10-15 Omnigene Bioproducts Inc. Pantoteenhappe võimendatud produktsiooni meetod
CA2434626A1 (fr) * 2001-01-19 2002-08-08 Basf Aktiengesellschaft Micro-organismes et procedes de production amelioree de pantothenate
ES2278929T3 (es) 2001-02-21 2007-08-16 Basf Aktiengesellschaft Procedimiento para la obtencion del acido d-pantotenico y/o sales como aditivos para piensos de animales.
PL363917A1 (en) 2001-02-21 2004-11-29 Basf Aktiengesellschaft Method for producing d-pantothenic acid and/or salts thereof as an additive for animal feed
DE10108223A1 (de) * 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
DE10108225A1 (de) * 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
EP1247868A3 (fr) * 2001-04-03 2002-10-30 Degussa AG Procédé pour la production d'acide D-pantothénique et/ou de ses sels par fermentation
WO2003004672A1 (fr) * 2001-07-03 2003-01-16 Degussa Ag Methode de preparation par fermentation de l'acide d-pantothenique et/ou des sels dudit acide
WO2003004673A1 (fr) * 2001-07-03 2003-01-16 Degussa Ag Procede pour preparer par fermentation de l'acide d-pantothenique et/ou des sels de celui-ci
DE10132178A1 (de) 2001-07-03 2003-01-23 Degussa Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen
EP1672073A1 (fr) * 2001-07-07 2006-06-21 Degussa AG Procédé pour préparer de l'acide D-Pantothenique et/ou des sels d'acide D-Pantothenique
US7338792B2 (en) 2001-07-07 2008-03-04 Degussa Ag Process for the preparation of D-pantothenic acid and/or salts thereof
ATE432338T1 (de) * 2002-01-18 2009-06-15 Novozymes As Alanin-2,3-aminomutase
MXPA04012812A (es) 2002-07-03 2005-02-24 Basf Ag Microorganismos y proceso para la produccion aumentada de pantotenato.
CA2491137A1 (fr) * 2002-07-03 2004-01-15 Basf Aktiengesellschaft Micro-organismes et procedes de production amelioree de pantothenate
WO2004113510A2 (fr) * 2003-06-18 2004-12-29 Dsm Ip Assets B.V. Production de pantothenate au moyen de micro-organismes inaptes a la sporulation
EP1876235A4 (fr) * 2005-03-29 2008-07-09 Kaneka Corp Nouveau gène de la pantothénate kinase et son utilisation
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
NZ566406A (en) 2005-10-26 2012-04-27 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
DE112007001179T5 (de) 2006-05-16 2009-04-02 Dsm Ip Assets B.V. Verfahren zur Herstellung von Panthenol
EP1918383A1 (fr) * 2006-11-02 2008-05-07 DSMIP Assets B.V. Procédé de fermentation semi-continue pour la production de pantothénate
EP2118266A4 (fr) 2007-02-09 2010-05-19 Univ California Production de biocarburant par des micro-organismes recombinants
WO2009007326A2 (fr) 2007-07-06 2009-01-15 Basf Se Procédé de préparation d'une solution de glucose aqueuse
PL2265709T3 (pl) * 2008-03-27 2018-05-30 Genomatica, Inc. Mikroorganizmy do produkcji kwasu adypinowego i innych związków
EP2157174A1 (fr) 2008-08-12 2010-02-24 DSM IP Assets B.V. Production de pantothenate (vitamine B5) améliorée
EP2673369B1 (fr) * 2011-02-07 2017-04-05 William Marsh Rice University Voie de bêta-oxydation inverse
US8765426B2 (en) * 2011-04-07 2014-07-01 E I Du Pont De Nemours And Company Pantothenic acid biosynthesis in zymomonas
EP2723878B1 (fr) 2011-06-21 2020-05-20 DSM IP Assets B.V. Production de vitamine b5
WO2012175574A1 (fr) 2011-06-21 2012-12-27 Dsm Ip Assets B.V. Production accrue de pantothénate (vitamine b5)
WO2014087184A1 (fr) * 2012-12-03 2014-06-12 Metabolic Explorer Production par fermentation de néopentyl glycol par un micro-organisme recombinant
WO2015061792A1 (fr) 2013-10-25 2015-04-30 Retrophin, Inc. Dérivés panothénate pour le traitement de troubles neurologiques
CN104593398B (zh) * 2013-11-01 2017-06-06 中国科学院微生物研究所 一种高L‑天冬氨酸α羧化酶活性的工程菌及其在生产β‑丙氨酸中的应用
CN105368758B (zh) * 2015-03-16 2018-06-19 鲁东大学 一株高产天冬氨酸脱羧酶的菌株及用于生产丙氨酸的方法
CN108486110A (zh) * 2015-03-31 2018-09-04 中国农业科学院生物技术研究所 一种启动子和重组表达载体及其用途
MX2018006636A (es) 2015-12-08 2018-08-15 Retrophin Inc Fosfatos ciclicos y fosforoamidatos ciclicos para el tratamiento de trastornos neurologicos.
EP3645725A1 (fr) 2017-06-30 2020-05-06 PTT Global Chemical Public Company Limited Micro-organisme ayant un nombre de copies stabilisé d'une séquence d'adn fonctionnelle et méthodes associées
CN108456701B (zh) * 2018-03-23 2020-10-16 精晶药业股份有限公司 一种d-泛解酸内酯的制备方法
WO2020005834A1 (fr) * 2018-06-25 2020-01-02 Lygos, Inc. Cellules hôtes recombinées et procédés de production d'acide aspartique et de β-alanine
MX2021000323A (es) 2018-07-09 2021-03-25 Codexis Inc Enzimas de variante de pantotenato quinasa modificadas geneticamente.
EP4174185A4 (fr) * 2020-06-28 2024-05-22 Mint Biotechnologies Co., Ltd. Procédés de préparation d'acide pantoïque, d'acide pantothénique et de panthénol ainsi que leurs sels
KR102389327B1 (ko) * 2020-07-01 2022-04-20 씨제이제일제당 (주) 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도
CN115109736B (zh) * 2021-03-23 2024-05-07 中国科学院天津工业生物技术研究所 一种产泛解酸的微生物及其构建方法和应用
EP4108654A1 (fr) 2021-06-23 2022-12-28 DSM IP Assets B.V. Production de panthénol
EP4323331A1 (fr) 2021-04-15 2024-02-21 DSM IP Assets B.V. Production de panthénol
CN114085820B (zh) * 2021-11-19 2023-10-20 万华化学集团股份有限公司 来源于Candida viswanathii的酮基泛解酸内酯还原酶
CN114437988B (zh) * 2022-02-28 2023-05-23 贵州医科大学 纤维素降解菌及菌剂、制备方法、应用和降解酒糟的方法
CN115595328A (zh) * 2022-03-07 2023-01-13 中国科学院微生物研究所（Cn） 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN115595314B (zh) * 2022-03-07 2025-06-24 中国科学院微生物研究所 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法
CN120187698A (zh) 2022-11-21 2025-06-20 帝斯曼知识产权资产管理有限公司 泛醇的生产
EP4378923A1 (fr) 2022-12-01 2024-06-05 DSM IP Assets B.V. Production de panthénol
KR102879056B1 (ko) 2023-01-27 2025-10-30 씨제이제일제당 (주) 글루타미시박터 할로피토콜라 유래 판토에이트-베타-알라닌 리가아제의 활성이 강화된 미생물 및 이의 용도
KR102879057B1 (ko) 2023-01-27 2025-10-30 씨제이제일제당 (주) 아르카노박테리움 포시시마일 유래 판토에이트-베타-알라닌 리가아제의 활성이 강화된 미생물 및 이의 용도
CN116590209A (zh) * 2023-06-13 2023-08-15 浙江工业大学 一种产d-泛酸的基因工程菌、构建方法及应用
CN119709733B (zh) * 2023-09-28 2025-11-28 安徽华恒生物科技股份有限公司 一种动态调控系统、泛解酸生产菌株及其制备方法和应用
CN119220576B (zh) * 2024-12-03 2025-07-25 浙江工业大学 基于一碳单位供应的产d-泛酸基因工程菌及构建与应用
CN120060194B (zh) * 2025-02-27 2025-10-28 中国农业科学院植物保护研究所 一种用于提高放线菌聚酮类天然产物产量的组合模块及含有其重组菌的构建与应用
CN121046335A (zh) * 2025-11-06 2025-12-02 诸城市浩天药业有限公司 一种耐热、半衰期长的泛酸合成酶突变体

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DE19855313A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen

Also Published As

Publication number Publication date
IL148786A0 (en) 2002-09-12
MXPA02003017A (es) 2004-09-06
KR20020092912A (ko) 2002-12-12
HUP0202705A2 (hu) 2002-12-28
WO2001021772A3 (fr) 2002-03-07
WO2001021772A9 (fr) 2002-12-05
BR0014115A (pt) 2002-05-21
PL356566A1 (en) 2004-06-28
HU230509B1 (hu) 2016-09-28
EP2163629A3 (fr) 2010-06-02
CA2385497A1 (fr) 2001-03-29
CZ20021013A3 (en) 2002-12-11
WO2001021772A2 (fr) 2001-03-29
TR200200751T2 (tr) 2004-08-23
AU7708700A (en) 2001-04-24
HUP0202705A3 (en) 2011-02-28
JP5392957B2 (ja) 2014-01-22
JP2003527828A (ja) 2003-09-24
EP2163629A2 (fr) 2010-03-17
SK5222002A3 (en) 2003-03-04
EP2163629B1 (fr) 2017-03-08
NO20021382D0 (no) 2002-03-20
EP1214420A2 (fr) 2002-06-19
BRPI0014115B1 (pt) 2015-05-05
CN1420931A (zh) 2003-05-28
BRPI0014115B8 (pt) 2021-05-25
EP1214420B1 (fr) 2016-03-23

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