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NO20021686L - Methods for Preparation of Target Molecules in a Transgenic Animal and Purification of the Target Molecule - Google Patents

Methods for Preparation of Target Molecules in a Transgenic Animal and Purification of the Target Molecule

Info

Publication number
NO20021686L
NO20021686L NO20021686A NO20021686A NO20021686L NO 20021686 L NO20021686 L NO 20021686L NO 20021686 A NO20021686 A NO 20021686A NO 20021686 A NO20021686 A NO 20021686A NO 20021686 L NO20021686 L NO 20021686L
Authority
NO
Norway
Prior art keywords
purification
preparation
methods
target
transgenic animal
Prior art date
Application number
NO20021686A
Other languages
Norwegian (no)
Other versions
NO20021686D0 (en
Inventor
Harry M Meade
Scott P Fulton
Yann Echelard
Original Assignee
Genzyme Transgenics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Transgenics Corp filed Critical Genzyme Transgenics Corp
Publication of NO20021686D0 publication Critical patent/NO20021686D0/en
Publication of NO20021686L publication Critical patent/NO20021686L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20021686A 1999-10-14 2002-04-10 Methods for Preparation of Target Molecules in a Transgenic Animal and Purification of the Target Molecule NO20021686L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15974899P 1999-10-14 1999-10-14
US20466200P 2000-05-17 2000-05-17
PCT/US2000/028589 WO2001026455A1 (en) 1999-10-14 2000-10-16 Methods of producing a target molecule in a transgenic animal and purification of the target molecule

Publications (2)

Publication Number Publication Date
NO20021686D0 NO20021686D0 (en) 2002-04-10
NO20021686L true NO20021686L (en) 2002-06-12

Family

ID=26856252

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021686A NO20021686L (en) 1999-10-14 2002-04-10 Methods for Preparation of Target Molecules in a Transgenic Animal and Purification of the Target Molecule

Country Status (14)

Country Link
EP (1) EP1220606A4 (en)
JP (1) JP2003511048A (en)
KR (1) KR100772465B1 (en)
CN (1) CN1322003C (en)
AU (1) AU781944B2 (en)
BR (1) BR0014860A (en)
CA (1) CA2382741A1 (en)
HU (1) HUP0203537A2 (en)
IL (1) IL149003A0 (en)
MX (1) MXPA02003702A (en)
NO (1) NO20021686L (en)
NZ (1) NZ518263A (en)
RU (1) RU2002112460A (en)
WO (1) WO2001026455A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800462B2 (en) * 2001-09-10 2004-10-05 Abgenomics Corporation Production of recombinant proteins in vivo and use for generating antibodies
US20030049694A1 (en) * 2001-09-10 2003-03-13 Chung-Hsiun Wu Production of fusion proteins and use for identifying binding molecules
CN1283785C (en) * 2002-05-20 2006-11-08 上海杰隆生物工程股份有限公司 Method of producing human forcing erythrogenin using transgene animal mammary gland
US7527966B2 (en) 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
EP1924697A2 (en) * 2005-06-29 2008-05-28 Cameron Clokie Production of bone morphogenic proteins (bmps) in transgenic mammals
CA2690565A1 (en) * 2007-06-13 2008-12-24 Sterrenbeld Biotechnologie North America, Inc. Process for producing exogenous protein in the milk of transgenic mammals
WO2010036976A2 (en) 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of antibodies
WO2010036978A2 (en) 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of growth hormone
EP2417263B1 (en) 2009-04-09 2015-09-23 ProteoVec Holding L.L.C. Production of proteins using transposon-based vectors
CN104302312A (en) * 2011-12-19 2015-01-21 Lfb美国股份有限公司 Recombinant human alpha-1-antitrypsin for the treatment of inflammatory disorders
BR112015019341A2 (en) 2013-02-13 2017-08-22 Lab Francais Du Fractionnement ANTI-TNF-ALPHA ANTIBODY, COMPOSITION COMPRISING THE ANTIBODY, METHOD FOR PRODUCING A POPULATION OF ANTIBODIES, MAMMARY GLAND EPITHELIAL CELLS, TRANSGENIC NON-HUMAN MAMMAL, AND, MONOCLONAL ANTI-TNF ANTIBODY COMPOSITION
EP2956003A2 (en) 2013-02-13 2015-12-23 Laboratoire Français du Fractionnement et des Biotechnologies Proteins with modified glycosylation and methods of production thereof
JP2016532100A (en) 2013-07-05 2016-10-13 ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ Affinity chromatography matrix
FR3025515B1 (en) 2014-09-05 2016-09-09 Lab Francais Du Fractionnement PROCESS FOR PURIFYING MONOCLONAL ANTIBODY
FR3034420A1 (en) 2015-03-31 2016-10-07 Lab Francais Du Fractionnement ANTI-CD303 MONOCLONAL ANTIBODIES
FR3038517B1 (en) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies USE OF MODIFIED FC FRAGMENTS IN IMMUNOTHERAPY
JP6712125B2 (en) * 2015-09-04 2020-06-17 株式会社フジクラ Connection structure of oxide superconducting wire and method for manufacturing the same
FR3060395B1 (en) 2016-12-16 2019-05-24 Laboratoire Francais Du Fractionnement Et Des Biotechnologies COMBINATION OF ANTI-CD303 AND ANTI-HER2 ANTIBODIES
FR3060394B1 (en) 2016-12-16 2019-05-24 Laboratoire Francais Du Fractionnement Et Des Biotechnologies COMBINATION OF ANTI-CD303 AND ANTI-AMHRII ANTIBODIES
FR3076294B1 (en) 2017-12-29 2022-01-28 Lab Francais Du Fractionnement METHOD FOR PURIFYING ANTIBODIES FROM RAW MILK
MX2024007676A (en) 2021-12-20 2024-08-28 Vetoquinol Sa Anti-canine interleukine-31-receptor a (il-31ra) antibodies and the uses thereof.
WO2024165823A2 (en) 2023-02-09 2024-08-15 Commissariat A L'energie Atomique Et Aux Energies Alternatives Mutant fab fragment for obtaining site-specific mono-or bifunctionalised conjugates
WO2025114614A1 (en) 2023-11-30 2025-06-05 Vetoquinol Sa Anti-canine interleukine-4-receptor alpha (il-4rα) antibodies and the uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK580789D0 (en) * 1989-11-20 1989-11-20 Novo Nordisk As PROCEDURE FOR PURIFICATION OF POLYPEPTIDES
US5639940A (en) * 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
CN1114357A (en) * 1994-07-01 1996-01-03 唐勇炜 Process for producing recombinative polypeptide using transgene animal

Also Published As

Publication number Publication date
AU8025400A (en) 2001-04-23
EP1220606A4 (en) 2004-04-14
JP2003511048A (en) 2003-03-25
HUP0203537A2 (en) 2003-02-28
KR100772465B1 (en) 2007-11-02
NO20021686D0 (en) 2002-04-10
KR20030022759A (en) 2003-03-17
MXPA02003702A (en) 2002-09-18
WO2001026455A1 (en) 2001-04-19
RU2002112460A (en) 2004-02-27
CN1322003C (en) 2007-06-20
IL149003A0 (en) 2002-11-10
BR0014860A (en) 2003-07-08
EP1220606A1 (en) 2002-07-10
AU781944B2 (en) 2005-06-23
NZ518263A (en) 2004-03-26
CA2382741A1 (en) 2001-04-19
CN1387399A (en) 2002-12-25

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