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NO20016351L - C-pyrazol A2A reseptoragonister - Google Patents

C-pyrazol A2A reseptoragonister

Info

Publication number
NO20016351L
NO20016351L NO20016351A NO20016351A NO20016351L NO 20016351 L NO20016351 L NO 20016351L NO 20016351 A NO20016351 A NO 20016351A NO 20016351 A NO20016351 A NO 20016351A NO 20016351 L NO20016351 L NO 20016351L
Authority
NO
Norway
Prior art keywords
pyrazole
receptor agonists
agonists
receptor
Prior art date
Application number
NO20016351A
Other languages
English (en)
Other versions
NO323163B1 (no
NO20016351D0 (no
Inventor
Jeff A Zablocki
Elfatih O Elzein
Venkata P Palle
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Publication of NO20016351D0 publication Critical patent/NO20016351D0/no
Publication of NO20016351L publication Critical patent/NO20016351L/no
Publication of NO323163B1 publication Critical patent/NO323163B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20016351A 1999-06-22 2001-12-21 C-pyrazol A2A reseptoragonister NO323163B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/338,327 US6214807B1 (en) 1999-06-22 1999-06-22 C-pyrazole 2A A receptor agonists
PCT/US2000/017095 WO2000078778A2 (en) 1999-06-22 2000-06-21 C-pyrazole a2a receptor agonists

Publications (3)

Publication Number Publication Date
NO20016351D0 NO20016351D0 (no) 2001-12-21
NO20016351L true NO20016351L (no) 2002-02-18
NO323163B1 NO323163B1 (no) 2007-01-08

Family

ID=23324355

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016351A NO323163B1 (no) 1999-06-22 2001-12-21 C-pyrazol A2A reseptoragonister

Country Status (23)

Country Link
US (6) US6214807B1 (no)
EP (1) EP1192169B1 (no)
JP (1) JP4795591B2 (no)
KR (1) KR100511733B1 (no)
CN (1) CN1152041C (no)
AR (1) AR033794A1 (no)
AT (1) ATE240341T1 (no)
AU (1) AU766712B2 (no)
BR (1) BR0011854A (no)
CA (1) CA2375430C (no)
DE (1) DE60002722T2 (no)
DK (1) DK1192169T3 (no)
ES (1) ES2193969T3 (no)
HK (1) HK1044953A1 (no)
IL (2) IL147195A0 (no)
MX (1) MXPA01013350A (no)
NO (1) NO323163B1 (no)
NZ (1) NZ516335A (no)
PT (1) PT1192169E (no)
TR (1) TR200200320T2 (no)
TW (1) TW589321B (no)
WO (1) WO2000078778A2 (no)
ZA (1) ZA200200298B (no)

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AU2001238665A1 (en) * 2000-02-23 2001-09-03 Cv Therapeutics, Inc. Method of identifying partial agonists of the a2a receptor
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US7262176B2 (en) * 2001-08-08 2007-08-28 Cv Therapeutics, Inc. Adenosine A3 receptor agonists
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US8470801B2 (en) 2002-07-29 2013-06-25 Gilead Sciences, Inc. Myocardial perfusion imaging methods and compositions
EP1537135B1 (en) 2002-09-09 2009-11-25 Cv Therapeutics, Inc. Adenosine a3 receptor agonists
PT2366396E (pt) * 2004-01-27 2013-10-03 Gilead Sciences Inc Imagiologia de perfusão miocárdica utilizando agonistas do receptor de adenosina
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CN101068825B (zh) * 2004-08-02 2013-05-08 弗吉尼亚大学专利基金会 具有a2a激动剂活性的具有修饰的5＇-核糖基团的2-丙炔基腺苷类似物
CN101437526A (zh) * 2004-09-20 2009-05-20 伊诺泰克制药公司 嘌呤衍生物及其用法
CN101076343A (zh) 2004-10-20 2007-11-21 Cv医药有限公司 A2a腺苷受体激动剂的应用
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US7732424B2 (en) 2005-11-30 2010-06-08 Inotek Pharmaceuticals Corporation Purine derivatives and methods of use thereof
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CA2655310A1 (en) * 2006-06-22 2008-05-29 Cv Therapeutics, Inc. Use of a2a adenosine receptor agonists in the treatment of ischemia
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US20090081120A1 (en) * 2006-09-01 2009-03-26 Cv Therapeutics, Inc. Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods
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MX2011003168A (es) * 2008-09-29 2011-05-19 Gilead Sciences Inc Combinaciones de un agente de control de cantidad y un antagonista del receptor a-2-alfa para utilizarse en metodos de tomografia computarizada de detectores multiples.
SI2523669T1 (sl) 2010-01-11 2017-05-31 Inotek Pharmaceuticals Corporation Kombinacija, komplet in metoda za zmanjšanje intraokularnega tlaka
PH12012501906A1 (en) 2010-03-26 2013-01-14 Inotek Pharmaceuticals Corp Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof
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Also Published As

Publication number Publication date
WO2000078778A2 (en) 2000-12-28
US6770634B1 (en) 2004-08-03
CA2375430A1 (en) 2000-12-28
US6214807B1 (en) 2001-04-10
US7109180B2 (en) 2006-09-19
US20040198692A1 (en) 2004-10-07
DE60002722D1 (de) 2003-06-18
EP1192169A2 (en) 2002-04-03
ATE240341T1 (de) 2003-05-15
KR20020028911A (ko) 2002-04-17
US20070207978A1 (en) 2007-09-06
IL147195A0 (en) 2002-08-14
JP4795591B2 (ja) 2011-10-19
US7553823B2 (en) 2009-06-30
DK1192169T3 (da) 2003-08-04
CN1358189A (zh) 2002-07-10
BR0011854A (pt) 2002-06-11
NO323163B1 (no) 2007-01-08
EP1192169B1 (en) 2003-05-14
JP2003506460A (ja) 2003-02-18
US20010018428A1 (en) 2001-08-30
AU5755800A (en) 2001-01-09
CA2375430C (en) 2006-03-14
IL147195A (en) 2007-10-31
TR200200320T2 (tr) 2002-05-21
TW589321B (en) 2004-06-01
AU766712B2 (en) 2003-10-23
AR033794A1 (es) 2004-01-07
ES2193969T3 (es) 2003-11-16
NZ516335A (en) 2003-10-31
MXPA01013350A (es) 2002-07-09
US6855818B2 (en) 2005-02-15
KR100511733B1 (ko) 2005-08-31
NO20016351D0 (no) 2001-12-21
WO2000078778A3 (en) 2001-05-10
ZA200200298B (en) 2003-04-30
HK1044953A1 (zh) 2002-11-08
DE60002722T2 (de) 2004-04-08
CN1152041C (zh) 2004-06-02
PT1192169E (pt) 2003-09-30
US20100081810A1 (en) 2010-04-01

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