NO20014864L - Substituerte 1,4-dihydro-indeno [1,2-C] pyrazoler som inhibitorer av tyrosin kinase - Google Patents

Substituerte 1,4-dihydro-indeno [1,2-C] pyrazoler som inhibitorer av tyrosin kinase

Info

Publication number: NO20014864L
Authority: NO; Norway
Prior art keywords: pyrazoles; inhibitors; dihydroindeno; substituted; tyrosine kinase
Prior art date: 1999-04-06

Application number

NO20014864A

Other languages

English (en)

Norwegian (no)

Other versions

NO20014864D0 (no

Inventor

Kevin J Doyle

Paul Rafferty

Robert William Steele

Allyson Turner

David J Wilkins

Lee Daniel Arnold

Original Assignee

Knoll Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-06

Filing date

2001-10-05

Publication date

2001-12-05

2001-10-05 Application filed by Knoll Gmbh filed Critical Knoll Gmbh

2001-10-05 Publication of NO20014864D0 publication Critical patent/NO20014864D0/no

2001-12-05 Publication of NO20014864L publication Critical patent/NO20014864L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO20014864A 1999-04-06 2001-10-05 Substituerte 1,4-dihydro-indeno [1,2-C] pyrazoler som inhibitorer av tyrosin kinase NO20014864L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12796399P	1999-04-06	1999-04-06
PCT/US2000/008192 WO2000059901A1 (fr)	1999-04-06	2000-03-28	1,4 dihydroindeno[1, 2-c]pyrazoles substitues utilises comme inhibiteurs de la tyrosine kinase

Publications (2)

Publication Number	Publication Date
NO20014864D0 NO20014864D0 (no)	2001-10-05
NO20014864L true NO20014864L (no)	2001-12-05

Family

ID=22432894

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20014864A NO20014864L (no)	1999-04-06	2001-10-05	Substituerte 1,4-dihydro-indeno [1,2-C] pyrazoler som inhibitorer av tyrosin kinase

Country Status (25)

Country	Link
EP (1)	EP1165544B1 (fr)
JP (1)	JP2002541150A (fr)
KR (1)	KR20020015034A (fr)
CN (1)	CN1368970A (fr)
AT (1)	ATE246684T1 (fr)
AU (1)	AU4037800A (fr)
BG (1)	BG106044A (fr)
BR (1)	BR0009561A (fr)
CA (1)	CA2368686A1 (fr)
CZ (1)	CZ20013580A3 (fr)
DE (1)	DE60004340T2 (fr)
DK (1)	DK1165544T3 (fr)
ES (1)	ES2207497T3 (fr)
HK (1)	HK1045500A1 (fr)
HU (1)	HUP0201514A3 (fr)
IL (1)	IL145564A0 (fr)
MX (1)	MXPA01010072A (fr)
NO (1)	NO20014864L (fr)
NZ (1)	NZ514269A (fr)
PL (1)	PL350891A1 (fr)
PT (1)	PT1165544E (fr)
SK (1)	SK14112001A3 (fr)
TR (1)	TR200103789T2 (fr)
WO (1)	WO2000059901A1 (fr)
ZA (1)	ZA200107838B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6462036B1 (en) *	1998-11-06	2002-10-08	Basf Aktiengesellschaft	Tricyclic pyrazole derivatives
US6297238B1 (en) *	1999-04-06	2001-10-02	Basf Aktiengesellschaft	Therapeutic agents
EP1444207A2 (fr)	2001-09-19	2004-08-11	Pharmacia Corporation	Composes de pyrazole substitues pour le traitement de l'inflammation
BR0212661A (pt)	2001-09-19	2004-08-24	Pharmacia Corp	Compostos de pirazolil benzenossulfamida substituìdos para o tratamento de inflamação
WO2003070236A2 (fr) *	2002-02-19	2003-08-28	Pharmacia Italia S.P.A.	Derives de pyrazole tricyclique, procedes de leur preparation et leur utilisation en tant qu'agents anti-tumoraux
DE60326950D1 (de) *	2002-05-15	2009-05-14	Janssen Pharmaceutica Nv	N-substituierte tricyclische 3-aminopyrazole als pdgf rezeptorenhemmer
MXPA05008688A (es) *	2003-02-17	2005-10-05	Pharmacia Italia Spa	Derivados tetraciclicos de pirazol como inhibidores de la cinasa, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden.
KR20050106465A (ko) *	2003-02-27	2005-11-09	아보트 러보러터리즈	헤테로사이클릭 키나제 억제제
MXPA05009576A (es) *	2003-03-07	2005-12-12	Abbott Lab	Inhibidores de pirazol-quinasa triciclicos y tetraciclicos, fundidos.
US7320986B2 (en)	2003-03-07	2008-01-22	Abbott Labortories	Fused tri and tetra-cyclic pyrazole kinase inhibitors
CA2560691A1 (fr)	2004-03-24	2005-10-13	Abbott Laboratories	Inhibiteurs de kinases a base de tyrazoles tricycliques
JP5351254B2 (ja) *	2008-05-23	2013-11-27	ノバルティスアーゲー	キノキサリン−およびキノリン−カルボキシアミド誘導体
AT507953B1 (de)	2009-03-05	2011-02-15	Apeptico Forschung & Entwicklung Gmbh	Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
US8853207B2 (en)	2012-04-12	2014-10-07	Development Center For Biotechnology	Heterocyclic pyrazole compounds, method for preparing the same and use thereof
CN104610149B (zh) *	2015-02-10	2017-04-05	山东大学	一种茚并吡唑类小分子微管蛋白抑制剂及其制备方法与应用
WO2025031474A1 (fr) *	2023-08-10	2025-02-13	Insilico Medicine Ip Limited	Méthode et médicament pour le traitement de l'endométriose

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9226855D0 (en) *	1992-12-23	1993-02-17	Erba Carlo Spa	Vinylene-azaindole derivatives and process for their preparation
CA2304466A1 (fr) *	1997-10-06	1999-04-15	Basf Aktiengesellschaft	Derives d'indeno[1,2-c]pyrazole utiles pour inhiber l'activite de tyrosine kinase
CN1335836A (zh) *	1998-11-06	2002-02-13	巴斯福股份公司	三环吡唑衍生物

2000
- 2000-03-28 KR KR1020017012696A patent/KR20020015034A/ko not_active Ceased
- 2000-03-28 HU HU0201514A patent/HUP0201514A3/hu unknown
- 2000-03-28 DK DK00919742T patent/DK1165544T3/da active
- 2000-03-28 JP JP2000609412A patent/JP2002541150A/ja not_active Withdrawn
- 2000-03-28 HK HK02104887.6A patent/HK1045500A1/zh unknown
- 2000-03-28 EP EP00919742A patent/EP1165544B1/fr not_active Expired - Lifetime
- 2000-03-28 WO PCT/US2000/008192 patent/WO2000059901A1/fr not_active Ceased
- 2000-03-28 BR BR0009561-3A patent/BR0009561A/pt not_active IP Right Cessation
- 2000-03-28 CN CN00808326A patent/CN1368970A/zh active Pending
- 2000-03-28 AU AU40378/00A patent/AU4037800A/en not_active Abandoned
- 2000-03-28 MX MXPA01010072A patent/MXPA01010072A/es unknown
- 2000-03-28 DE DE60004340T patent/DE60004340T2/de not_active Expired - Fee Related
- 2000-03-28 TR TR2001/03789T patent/TR200103789T2/xx unknown
- 2000-03-28 CZ CZ20013580A patent/CZ20013580A3/cs unknown
- 2000-03-28 SK SK1411-2001A patent/SK14112001A3/sk unknown
- 2000-03-28 NZ NZ514269A patent/NZ514269A/en unknown
- 2000-03-28 PT PT00919742T patent/PT1165544E/pt unknown
- 2000-03-28 ES ES00919742T patent/ES2207497T3/es not_active Expired - Lifetime
- 2000-03-28 CA CA002368686A patent/CA2368686A1/fr not_active Abandoned
- 2000-03-28 PL PL00350891A patent/PL350891A1/xx not_active Application Discontinuation
- 2000-03-28 AT AT00919742T patent/ATE246684T1/de not_active IP Right Cessation
- 2000-03-28 IL IL14556400A patent/IL145564A0/xx unknown
2001
- 2001-09-21 ZA ZA200107838A patent/ZA200107838B/en unknown
- 2001-10-05 NO NO20014864A patent/NO20014864L/no not_active Application Discontinuation
- 2001-10-24 BG BG106044A patent/BG106044A/xx unknown

Also Published As

Publication number	Publication date
CZ20013580A3 (cs)	2002-03-13
HUP0201514A3 (en)	2003-11-28
PT1165544E (pt)	2003-12-31
EP1165544A1 (fr)	2002-01-02
ATE246684T1 (de)	2003-08-15
BG106044A (en)	2002-05-31
EP1165544B1 (fr)	2003-08-06
MXPA01010072A (es)	2004-03-26
NZ514269A (en)	2003-10-31
DK1165544T3 (da)	2003-12-01
DE60004340D1 (de)	2003-09-11
KR20020015034A (ko)	2002-02-27
CN1368970A (zh)	2002-09-11
DE60004340T2 (de)	2004-06-09
ZA200107838B (en)	2003-03-24
HUP0201514A2 (en)	2002-08-28
IL145564A0 (en)	2002-06-30
CA2368686A1 (fr)	2000-10-12
HK1045500A1 (zh)	2002-11-29
AU4037800A (en)	2000-10-23
PL350891A1 (en)	2003-02-10
SK14112001A3 (sk)	2002-04-04
TR200103789T2 (tr)	2002-04-22
JP2002541150A (ja)	2002-12-03
WO2000059901A1 (fr)	2000-10-12
NO20014864D0 (no)	2001-10-05
BR0009561A (pt)	2002-04-16
ES2207497T3 (es)	2004-06-01

Publication	Publication Date	Title
NO20005535L (no)	2000-11-02	Pyrazol-derivater som P-38 MAP kinase-inhibitorer
MXPA02011320A (es)	2004-09-10	Derivados de pirazol triciclico como inhibidores de cinasa.
NO20014864L (no)	2001-12-05	Substituerte 1,4-dihydro-indeno [1,2-C] pyrazoler som inhibitorer av tyrosin kinase
MXPA03010207A (es)	2004-03-10	Nuevas 4-anilinoquinolin-3-carboxamidas.
EA200300248A1 (ru)	2003-08-28	Бициклопиразолы, активные в качестве ингибиторов киназы, способ их получения и включающие их фармацевтические композиции
BR9915132A (pt)	2001-08-07	Método para inibir a atividade de quinase de proteìna, compostos da fórmula i e sais farmaceuticamente aceitáveis dos mesmos, uso do mesmo, e, composição farmacêutica.
ATE377597T1 (de)	2007-11-15	Anilinochinazoline als protein-tyrosin- kinasehemmer
MXPA03011638A (es)	2004-04-02	Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
BR0014225A (pt)	2002-05-21	Derivados de pirazol
ATE253545T1 (de)	2003-11-15	Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren
DE69824029D1 (de)	2004-06-24	Bicyclische kinase inhibitoren
ES2243579T3 (es)	2005-12-01	Derivados de pirazolopirideno.
WO2002018321A3 (fr)	2003-04-10	Inhibiteurs de proteine tyrosine phosphatase d'acide amino(oxo)acetique
NO20040589L (no)	2004-03-19	Arylsulfonylderivater med 5-HT6 reseptor affinitet.
MXPA04005426A (es)	2004-10-11	Derivados de pirazol de anillos fuisionados.
MXPA04005809A (es)	2004-09-13	Inhibidores de proteinas quinasas.
BG106847A (bg)	2003-02-28	Заместени пиперазинови производни като инхибиторина микрозомалния триглицеридпренасящ протеин (mtp)
NO983444L (no)	1998-07-24	Benzo(c)kinolizin derivater, deres fremstilling og anvendelse som 5<alfa>-reduktaseinhibitorer
WO2002018323A3 (fr)	2002-06-27	Acides amino(oxo)acetiques inhibiteurs de la proteine tyrosine phosphatase
WO2002018363A3 (fr)	2002-06-27	Inhibiteurs de la proteine tyrosine phosphatase
ATE363481T1 (de)	2007-06-15	Pyrazolderivate als gnrh-inhibitoren

Legal Events

Date	Code	Title	Description
2004-12-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application