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NO20013101L - Ytre overflateproteiner, deres gener og deres anvendelse - Google Patents

Ytre overflateproteiner, deres gener og deres anvendelse

Info

Publication number
NO20013101L
NO20013101L NO20013101A NO20013101A NO20013101L NO 20013101 L NO20013101 L NO 20013101L NO 20013101 A NO20013101 A NO 20013101A NO 20013101 A NO20013101 A NO 20013101A NO 20013101 L NO20013101 L NO 20013101L
Authority
NO
Norway
Prior art keywords
genes
surface proteins
streptococcus
immunization
vaccines
Prior art date
Application number
NO20013101A
Other languages
English (en)
Other versions
NO20013101D0 (no
Inventor
Martin John Glenton Hughes
Joseph David Santangelo
Jonathan Douglas Lane
Robert Feldman
Joanne Christine Moore
Richard James Dobson
Caroline Joanne Henwood
Paul Everest
Rebecca Kerry Wilson
Gordon Dougan
Original Assignee
Microscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828346.8A external-priority patent/GB9828346D0/en
Priority claimed from GBGB9901233.8A external-priority patent/GB9901233D0/en
Priority claimed from GBGB9901234.6A external-priority patent/GB9901234D0/en
Priority claimed from GBGB9908321.4A external-priority patent/GB9908321D0/en
Priority claimed from GBGB9912036.2A external-priority patent/GB9912036D0/en
Priority claimed from GBGB9922596.3A external-priority patent/GB9922596D0/en
Application filed by Microscience Ltd filed Critical Microscience Ltd
Publication of NO20013101D0 publication Critical patent/NO20013101D0/no
Publication of NO20013101L publication Critical patent/NO20013101L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1018—Carboxy- and carbamoyl transferases (2.1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ifølge foreliggende oppfinnelse, er en serie av gener identifisert i Gruppe B Streptococcus, produktene av hvilken kan være lokalisert på den ytre overflaten av organismen. Genene eller funksjonelle fragmenter derav, kan være anvendelige ved fremstilling av terapeutiske midler, f.eks. vaksiner for immuniseringen av en pasient mot mikrobiell infeksjon.
NO20013101A 1998-12-22 2001-06-21 Ytre overflateproteiner, deres gener og deres anvendelse NO20013101L (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9828346.8A GB9828346D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9901233.8A GB9901233D0 (en) 1999-01-20 1999-01-20 Protein and compositions containing it
GBGB9901234.6A GB9901234D0 (en) 1999-01-20 1999-01-20 Protein and compositions containing it
GBGB9908321.4A GB9908321D0 (en) 1999-04-12 1999-04-12 Purine nucleoside phosphatase and compositions containing it
GBGB9912036.2A GB9912036D0 (en) 1999-05-24 1999-05-24 Glucose-6-phosphate isomerase and compositions containing it
GBGB9922596.3A GB9922596D0 (en) 1999-09-23 1999-09-23 Protein and compositions containing it
PCT/GB1999/004376 WO2000037490A2 (en) 1998-12-22 1999-12-22 Outer surface proteins, their genes, and their use

Publications (2)

Publication Number Publication Date
NO20013101D0 NO20013101D0 (no) 2001-06-21
NO20013101L true NO20013101L (no) 2001-08-13

Family

ID=27547330

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013101A NO20013101L (no) 1998-12-22 2001-06-21 Ytre overflateproteiner, deres gener og deres anvendelse

Country Status (23)

Country Link
US (3) US7217415B1 (no)
EP (2) EP1140994B1 (no)
JP (1) JP2002533065A (no)
KR (4) KR100818815B1 (no)
CN (3) CN1733800A (no)
AP (1) AP2006003504A0 (no)
AT (1) ATE297995T1 (no)
AU (1) AU758722B2 (no)
BR (1) BR9916473A (no)
CA (1) CA2354843A1 (no)
CZ (1) CZ20012174A3 (no)
DE (1) DE69925866T2 (no)
DK (1) DK1140994T3 (no)
EA (1) EA009885B1 (no)
ES (1) ES2241352T3 (no)
HU (1) HUP0201022A3 (no)
NO (1) NO20013101L (no)
NZ (4) NZ552871A (no)
OA (1) OA12425A (no)
PL (1) PL351027A1 (no)
PT (1) PT1140994E (no)
SI (1) SI1140994T1 (no)
WO (1) WO2000037490A2 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535122A (en) * 1998-12-22 2006-04-28 Microscience Ltd Gene and proteins, and their use
NZ552871A (en) * 1998-12-22 2008-11-28 Microscience Ltd Genes in Group B Streptococcus (GBS), and also related organisms, the products of which are associated with the outer surface of the organism, and are useful as targets for immunotherapy
US6890539B2 (en) * 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
WO2008152448A2 (en) * 2006-12-21 2008-12-18 Emergent Product Development Uk Limited Streptococcus proteins, and their use in vaccination
CN103060284A (zh) * 2012-10-31 2013-04-24 内蒙古民族大学 一种无乳链球菌pgk亚单位重组蛋白及其制备方法
CN110669711A (zh) * 2019-08-09 2020-01-10 中国水产科学研究院珠江水产研究所 基于pgk基因的重组乳酸乳球菌和无乳链球菌病疫苗

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3678702D1 (de) 1985-12-28 1991-05-16 Ohgen Research Lab Ltd Antitumorprotein-gen von streptococcus pyogenes su, plasmide, die das gen enthalten, transformantenzellen, die die plasmide beherbergen, und verfahren zur herstellung des antitumorproteins.
US5328996A (en) * 1989-03-29 1994-07-12 University Of Florida Research Foundation, Inc. Bacterial plasmin receptors as fibrinolytic agents
WO1993014198A1 (en) * 1992-01-08 1993-07-22 The Rockefeller University Multifunctional surface protein of streptococci
IL107458A0 (en) * 1992-11-02 1994-02-27 Gen Hospital Corp Conjugate vaccine against group b streptococcus
DE69432658T2 (de) * 1993-03-19 2004-04-08 Gunnar Lindahl Rib-protein, ein oberflächenprotein welches immunität gegen viele streptococcus-stämme der gruppe b verleiht, reinigungsverfahren für das rib-protein, testsatz und pharmazeutische zusammenstellung (arznei)
US6015889A (en) * 1993-03-19 2000-01-18 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
US6346392B1 (en) * 1996-11-27 2002-02-12 Smithkline Beecham Corporation Polynucleotides encoding a novel glutamine transport ATP-binding protein
WO1998018931A2 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
US7196164B2 (en) * 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
US7135560B1 (en) * 1997-07-02 2006-11-14 Sanofi Pasteur Limited Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6380370B1 (en) * 1997-08-14 2002-04-30 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
US6165763A (en) * 1997-10-30 2000-12-26 Smithkline Beecham Corporation Ornithine carbamoyltransferase
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
NZ552871A (en) * 1998-12-22 2008-11-28 Microscience Ltd Genes in Group B Streptococcus (GBS), and also related organisms, the products of which are associated with the outer surface of the organism, and are useful as targets for immunotherapy
US6890539B2 (en) * 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
NZ535122A (en) * 1998-12-22 2006-04-28 Microscience Ltd Gene and proteins, and their use
US6605709B1 (en) * 1999-04-09 2003-08-12 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics

Also Published As

Publication number Publication date
NZ525538A (en) 2004-10-29
EA200100701A1 (ru) 2001-12-24
HUP0201022A3 (en) 2004-07-28
EP1140994B1 (en) 2005-06-15
KR100866170B1 (ko) 2008-10-30
CN1733800A (zh) 2006-02-15
KR20080052527A (ko) 2008-06-11
BR9916473A (pt) 2002-01-15
EP1140994A1 (en) 2001-10-10
US20060104990A1 (en) 2006-05-18
CZ20012174A3 (cs) 2002-02-13
DE69925866D1 (de) 2005-07-21
KR20010099885A (ko) 2001-11-09
PT1140994E (pt) 2005-11-30
DE69925866T2 (de) 2005-11-24
NZ552871A (en) 2008-11-28
PL351027A1 (en) 2003-02-24
HK1039339A1 (en) 2002-04-19
WO2000037490A2 (en) 2000-06-29
JP2002533065A (ja) 2002-10-08
AU1877900A (en) 2000-07-12
NO20013101D0 (no) 2001-06-21
KR100818815B1 (ko) 2008-04-01
EP1574579A3 (en) 2006-02-22
ES2241352T3 (es) 2005-10-16
OA12425A (en) 2006-04-18
AU758722B2 (en) 2003-03-27
EP1574579A2 (en) 2005-09-14
NZ512296A (en) 2003-08-29
SI1140994T1 (sl) 2005-12-31
NZ542777A (en) 2007-11-30
US7217415B1 (en) 2007-05-15
EA009885B1 (ru) 2008-04-28
KR20070027665A (ko) 2007-03-09
AP2006003504A0 (en) 2006-02-28
HUP0201022A2 (en) 2002-08-28
DK1140994T3 (da) 2005-08-15
WO2000037490A3 (en) 2001-09-20
US20080226641A1 (en) 2008-09-18
CN101486756A (zh) 2009-07-22
CA2354843A1 (en) 2000-06-29
KR20060096515A (ko) 2006-09-11
CN1357045A (zh) 2002-07-03
ATE297995T1 (de) 2005-07-15

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