NO20006631L - Forbindelser oppnådd fra salvie-arter med antiviral aktivitet - Google Patents
Forbindelser oppnådd fra salvie-arter med antiviral aktivitetInfo
- Publication number
- NO20006631L NO20006631L NO20006631A NO20006631A NO20006631L NO 20006631 L NO20006631 L NO 20006631L NO 20006631 A NO20006631 A NO 20006631A NO 20006631 A NO20006631 A NO 20006631A NO 20006631 L NO20006631 L NO 20006631L
- Authority
- NO
- Norway
- Prior art keywords
- tetramers
- trimers
- antiviral activity
- compounds obtained
- groups
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- 235000002020 sage Nutrition 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 abstract 2
- 239000013638 trimer Substances 0.000 abstract 2
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241001072909 Salvia Species 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- YMGFTDKNIWPMGF-UCPJVGPRSA-N Salvianolic acid A Chemical class C([C@H](C(=O)O)OC(=O)\C=C\C=1C(=C(O)C(O)=CC=1)\C=C\C=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 YMGFTDKNIWPMGF-UCPJVGPRSA-N 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229940074360 caffeic acid Drugs 0.000 abstract 1
- 235000004883 caffeic acid Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F246/00—Copolymers in which the nature of only the monomers in minority is defined
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/104,363 US6037369A (en) | 1998-06-25 | 1998-06-25 | Compounds obtained from salvia species having antiviral Activity |
| PCT/US1999/014297 WO1999066942A1 (fr) | 1998-06-25 | 1999-06-25 | Composes provenant d'especes de salvia possedant une activite antivirale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20006631D0 NO20006631D0 (no) | 2000-12-22 |
| NO20006631L true NO20006631L (no) | 2001-02-26 |
Family
ID=22300096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20006631A NO20006631L (no) | 1998-06-25 | 2000-12-22 | Forbindelser oppnådd fra salvie-arter med antiviral aktivitet |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6037369A (fr) |
| EP (1) | EP1089747A1 (fr) |
| JP (1) | JP2002518455A (fr) |
| KR (1) | KR20010071580A (fr) |
| CN (1) | CN1312722A (fr) |
| AU (1) | AU740698B2 (fr) |
| BR (1) | BR9912218A (fr) |
| CA (1) | CA2335956A1 (fr) |
| CZ (1) | CZ20004858A3 (fr) |
| HU (1) | HUP0103398A2 (fr) |
| ID (1) | ID28792A (fr) |
| IL (1) | IL140483A0 (fr) |
| IS (1) | IS5792A (fr) |
| MX (1) | MXPA01000195A (fr) |
| NO (1) | NO20006631L (fr) |
| PL (1) | PL345086A1 (fr) |
| TR (1) | TR200100450T2 (fr) |
| WO (1) | WO1999066942A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5703198A (en) * | 1996-12-05 | 1998-06-29 | Georgetown University | Extracts of salvia species having antiviral activity |
| US6043276A (en) * | 1998-06-25 | 2000-03-28 | Georgetown University School Of Medicine | Compounds obtained from salvia species having antiviral activity |
| AU2001248209A1 (en) * | 2000-05-05 | 2001-11-20 | Parsenn-Produkte Ag | Preparation for topically treating manifestations caused by virus infections |
| SG98409A1 (en) * | 2000-06-21 | 2003-09-19 | Chi Chiang Yang | Pharmaceutical compositions and combinations for the treatment or prophylaxis of disorders related to hiv and retrovirus |
| JP2002020283A (ja) * | 2000-06-22 | 2002-01-23 | Yang Chi-Chiang | Ｈｉｖおよびレトロウイルスに関連する障害の処置または予防のための薬学的組成物および組み合わせ |
| KR20020005222A (ko) * | 2000-06-28 | 2002-01-17 | 치-치앙 양 | Ｈｉｖ 또는 레트로바이러스에 관련된 질환의 치료 또는예방용 약학적 조성물 및 조합물 |
| US7071227B2 (en) * | 2000-09-26 | 2006-07-04 | The Johns Hopkins University | Antiviral compositions and methods of use |
| US20070027209A1 (en) * | 2005-08-01 | 2007-02-01 | Lee Hyun C | Prevention and treatment of atherosclerosis with lithospermate B |
| KR100857687B1 (ko) * | 2007-03-28 | 2008-09-08 | 연세대학교 산학협력단 | 단삼으로부터 고농도의 마그네슘 리토스퍼메이트 ｂ를 분리하는 방법 및 마그네슘 리토스퍼메이트 b를 함유하는 단삼 추출물을 생산하는 방법. |
| RU2529491C2 (ru) * | 2009-03-30 | 2014-09-27 | ТАСЛИ ФАРМАСЬЮТИКАЛ ГРОУП Ко., Лтд. | Соединение сальвианоловой кислоты л, способ его приготовления и применения |
| CN101919836A (zh) * | 2009-06-17 | 2010-12-22 | 山东绿叶天然药物研究开发有限公司 | 迷迭香酸的新用途 |
| CN103054976B (zh) * | 2011-10-21 | 2014-09-24 | 上海中医药大学 | 一种治疗血小板减少症的中药组合物及其制备方法和应用 |
| CN103845403B (zh) * | 2014-02-27 | 2016-10-05 | 河南大学 | 丹参配方颗粒在制备预防和治疗艾滋病脑病药物方面的应用 |
| CN104974119B (zh) * | 2014-04-01 | 2018-10-19 | 中国科学院上海药物研究所 | 一种高纯度丹酚酸b镁及其制备方法 |
| CN108042524A (zh) * | 2017-12-21 | 2018-05-18 | 南方医科大学 | 丹酚酸b及其结构类似物在制备抗hpv病毒感染药物中的应用 |
| CN109771410B (zh) * | 2019-03-06 | 2020-11-24 | 湖北大学 | 紫草酸在制备抗乙肝病毒药物中的用途 |
| CN109771407B (zh) * | 2019-03-29 | 2021-11-26 | 成都医学院 | 迷迭香酸在制备抑制水痘-带状疱疹病毒的药物中的用途 |
| CN110922286B (zh) * | 2019-11-23 | 2022-08-16 | 上海化工研究院有限公司 | 一种非对称芳基取代富烯化合物及其制备方法与应用 |
| US20230210848A1 (en) * | 2020-04-30 | 2023-07-06 | Fujifilm Toyama Chemical Co., Ltd. | Coronavirus infection therapeutic agent formed through combination of pyrazine derivative and another coronavirus infection therapeutic drug |
| CN114712342B (zh) * | 2022-05-10 | 2023-04-21 | 湖北大学 | 紫草酸在制备抗流感病毒药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5178865A (en) * | 1990-06-19 | 1993-01-12 | Cedars-Sinai Medical Center | Chinese herbal extracts in the treatment of hiv related disease in vitro |
| US5346695A (en) * | 1991-03-27 | 1994-09-13 | Tampa Bay Research Institute | Methods of inhibiting HIV replication in vitro using polymers of p-hydroxylated cinnamic acids |
| AU5703198A (en) * | 1996-12-05 | 1998-06-29 | Georgetown University | Extracts of salvia species having antiviral activity |
-
1998
- 1998-06-25 US US09/104,363 patent/US6037369A/en not_active Expired - Fee Related
-
1999
- 1999-06-25 CZ CZ20004858A patent/CZ20004858A3/cs unknown
- 1999-06-25 PL PL99345086A patent/PL345086A1/xx unknown
- 1999-06-25 KR KR1020007014664A patent/KR20010071580A/ko not_active Withdrawn
- 1999-06-25 JP JP2000555628A patent/JP2002518455A/ja active Pending
- 1999-06-25 IL IL14048399A patent/IL140483A0/xx unknown
- 1999-06-25 CA CA002335956A patent/CA2335956A1/fr not_active Abandoned
- 1999-06-25 EP EP99930658A patent/EP1089747A1/fr not_active Withdrawn
- 1999-06-25 CN CN99809677A patent/CN1312722A/zh active Pending
- 1999-06-25 TR TR2001/00450T patent/TR200100450T2/xx unknown
- 1999-06-25 WO PCT/US1999/014297 patent/WO1999066942A1/fr not_active Ceased
- 1999-06-25 MX MXPA01000195A patent/MXPA01000195A/es not_active Application Discontinuation
- 1999-06-25 BR BR9912218-9A patent/BR9912218A/pt not_active Application Discontinuation
- 1999-06-25 ID IDW20002741A patent/ID28792A/id unknown
- 1999-06-25 HU HU0103398A patent/HUP0103398A2/hu unknown
- 1999-06-25 AU AU47149/99A patent/AU740698B2/en not_active Ceased
-
2000
- 2000-12-22 IS IS5792A patent/IS5792A/is unknown
- 2000-12-22 NO NO20006631A patent/NO20006631L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TR200100450T2 (tr) | 2001-07-23 |
| PL345086A1 (en) | 2001-12-03 |
| CA2335956A1 (fr) | 1999-12-29 |
| US6037369A (en) | 2000-03-14 |
| IS5792A (is) | 2000-12-22 |
| MXPA01000195A (es) | 2002-04-24 |
| WO1999066942A1 (fr) | 1999-12-29 |
| ID28792A (id) | 2001-07-05 |
| EP1089747A1 (fr) | 2001-04-11 |
| CZ20004858A3 (cs) | 2001-09-12 |
| BR9912218A (pt) | 2002-07-23 |
| NO20006631D0 (no) | 2000-12-22 |
| CN1312722A (zh) | 2001-09-12 |
| KR20010071580A (ko) | 2001-07-28 |
| IL140483A0 (en) | 2002-02-10 |
| AU4714999A (en) | 2000-01-10 |
| JP2002518455A (ja) | 2002-06-25 |
| AU740698B2 (en) | 2001-11-15 |
| HUP0103398A2 (hu) | 2002-01-28 |
| WO1999066942A9 (fr) | 2000-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |