NO20004580L - Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater - Google Patents
Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perboraterInfo
- Publication number
- NO20004580L NO20004580L NO20004580A NO20004580A NO20004580L NO 20004580 L NO20004580 L NO 20004580L NO 20004580 A NO20004580 A NO 20004580A NO 20004580 A NO20004580 A NO 20004580A NO 20004580 L NO20004580 L NO 20004580L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- och
- preparation
- perborates
- oxidation
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000001311 chemical methods and process Methods 0.000 title 1
- 230000003647 oxidation Effects 0.000 title 1
- 238000007254 oxidation reaction Methods 0.000 title 1
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 title 1
- 239000003085 diluting agent Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000009835 boiling Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Fremgangsmåte for fremstilling av en forbindelse med formel l hvor RL R2, R3 og R4 representerer henholdsvis a) (Ri=CH3; R2=OCH3; R3=CH3; R4=OCH3) eller b) (Ri=CH3; R2=OCH2CF3; R3=H; R4=H) eller c) (Ri=OCH3; R2=OCH3; R3=H og R4=OCHF2) og farmasøytisk akseptable salter derav, omfattende omsetning av en forbindelse med formel II hvor RI, R2, R3 og FM representerer henholdsvis a) (R!=CH3; R2=OCH3; R3=CH3; R4=OCH3) eller b) (R,=CH3; R2=OCH2CF3; R3=H; F<4=H) eller c) (Ri=OCH3; R2=OCH3; R3=H og R4= med et perboratsalt i et flytende fortynningsmiddel ved en pH i området 7,5 til 14 ved en temperatur i området 0°C til kokepunktet til det anvendte flytende fortynningsmiddel.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9805558.5A GB9805558D0 (en) | 1998-03-17 | 1998-03-17 | Chemical process` |
| PCT/EP1999/001574 WO1999047514A1 (en) | 1998-03-17 | 1999-03-11 | Chemical process for the production of sulphinyl derivatives by oxidation of the corresponding co-derivatives with perborates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20004580L true NO20004580L (no) | 2000-09-14 |
| NO20004580D0 NO20004580D0 (no) | 2000-09-14 |
Family
ID=10828629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20004580A NO20004580D0 (no) | 1998-03-17 | 2000-09-14 | Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1071678A1 (no) |
| JP (1) | JP2002506862A (no) |
| KR (1) | KR20010041948A (no) |
| CN (1) | CN1293670A (no) |
| AU (1) | AU3410699A (no) |
| BR (1) | BR9908835A (no) |
| CA (1) | CA2323422A1 (no) |
| GB (1) | GB9805558D0 (no) |
| HU (1) | HUP0101230A3 (no) |
| IL (1) | IL138001A0 (no) |
| NO (1) | NO20004580D0 (no) |
| SK (1) | SK13452000A3 (no) |
| TR (1) | TR200002670T2 (no) |
| TW (1) | TW473476B (no) |
| WO (1) | WO1999047514A1 (no) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19951960C2 (de) * | 1999-10-28 | 2002-06-27 | Gruenenthal Gmbh | Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate |
| CN100347167C (zh) * | 2001-02-02 | 2007-11-07 | 特瓦制药工业有限公司 | 取代的2－(2－吡啶基甲基)亚磺酰基－1h－苯并咪唑化合物的生产方法 |
| KR100547824B1 (ko) | 2001-12-29 | 2006-02-01 | 삼성전자주식회사 | 블루투스를 구비하는 이동통신 단말기에서 긴급구조요청방법 |
| EP1501824B1 (en) | 2002-08-21 | 2007-10-10 | Teva Pharmaceutical Industries Ltd | A method for the purification of lansoprazole |
| DE03789888T1 (de) | 2002-11-18 | 2005-08-18 | Teva Pharmaceutical Industries Ltd. | Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol |
| ES2383679T3 (es) * | 2002-12-06 | 2012-06-25 | Nycomed Gmbh | Procedimiento para la preparación de (S)-pantoprazol |
| EP1572680A2 (en) | 2002-12-19 | 2005-09-14 | Eva Pharmaceutical Industries Ltd. | Solid states of pantoprazole sodium, known pantoprazole sodium hydrates, processes for their preparation. |
| JP2006516574A (ja) | 2003-02-05 | 2006-07-06 | テバ ファーマシューティカル インダストリーズ リミティド | ランソプラゾール安定化方法 |
| US7683177B2 (en) | 2003-06-10 | 2010-03-23 | Teva Pharmaceutical Industries Ltd | Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
| EP1802584B1 (en) | 2004-10-11 | 2009-09-16 | Ranbaxy Laboratories Limited | Processes for the preparation of substituted sulfoxides |
| CN102603621B (zh) * | 2012-02-07 | 2013-09-04 | 成都苑东药业有限公司 | 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法 |
| CN107365300B (zh) * | 2017-07-26 | 2019-08-02 | 桂林华信制药有限公司 | 一种有效去除兰索拉唑粗品中杂质的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| SE8500996D0 (sv) * | 1985-03-01 | 1985-03-01 | Haessle Ab | Method of treatment |
| JPH0352887A (ja) * | 1989-07-20 | 1991-03-07 | Yoshitomi Pharmaceut Ind Ltd | ピリジン化合物 |
| ES2140391T3 (es) * | 1990-06-20 | 2000-03-01 | Astra Ab | Derivados de dialcoxi-piridinil-bencimidazol, procedimiento para su preparacion y su uso farmaceutico. |
| ES2026761A6 (es) * | 1990-10-31 | 1992-05-01 | Genesis Para La Investigacion | Procedimiento de obtencion del omeprazol. |
| KR100570104B1 (ko) * | 1997-07-11 | 2006-04-11 | 에자이 가부시키가이샤 | 피리딘 유도체의 제조방법 |
-
1998
- 1998-03-17 GB GBGB9805558.5A patent/GB9805558D0/en not_active Ceased
-
1999
- 1999-03-11 HU HU0101230A patent/HUP0101230A3/hu unknown
- 1999-03-11 BR BR9908835-5A patent/BR9908835A/pt not_active Application Discontinuation
- 1999-03-11 SK SK1345-2000A patent/SK13452000A3/sk unknown
- 1999-03-11 CN CN99804078A patent/CN1293670A/zh active Pending
- 1999-03-11 JP JP2000536710A patent/JP2002506862A/ja active Pending
- 1999-03-11 WO PCT/EP1999/001574 patent/WO1999047514A1/en not_active Ceased
- 1999-03-11 CA CA002323422A patent/CA2323422A1/en not_active Abandoned
- 1999-03-11 IL IL13800199A patent/IL138001A0/xx unknown
- 1999-03-11 TR TR2000/02670T patent/TR200002670T2/xx unknown
- 1999-03-11 AU AU34106/99A patent/AU3410699A/en not_active Abandoned
- 1999-03-11 KR KR1020007010261A patent/KR20010041948A/ko not_active Withdrawn
- 1999-03-11 EP EP99915569A patent/EP1071678A1/en not_active Withdrawn
- 1999-03-17 TW TW088104130A patent/TW473476B/zh active
-
2000
- 2000-09-14 NO NO20004580A patent/NO20004580D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0101230A3 (en) | 2002-10-28 |
| GB9805558D0 (en) | 1998-05-13 |
| KR20010041948A (ko) | 2001-05-25 |
| SK13452000A3 (sk) | 2001-04-09 |
| TW473476B (en) | 2002-01-21 |
| NO20004580D0 (no) | 2000-09-14 |
| WO1999047514A1 (en) | 1999-09-23 |
| CN1293670A (zh) | 2001-05-02 |
| IL138001A0 (en) | 2001-10-31 |
| CA2323422A1 (en) | 1999-09-23 |
| JP2002506862A (ja) | 2002-03-05 |
| HUP0101230A2 (hu) | 2001-10-28 |
| AU3410699A (en) | 1999-10-11 |
| EP1071678A1 (en) | 2001-01-31 |
| TR200002670T2 (tr) | 2000-11-21 |
| BR9908835A (pt) | 2000-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ID17851A (id) | Persenyawaan heterosiklis, produksi dan pemakaiannya | |
| MA21502A1 (fr) | 4--phenyl-(-piperazinyl)phenols et procedes pour leur preparation . | |
| NO20004580L (no) | Kjemisk fremgangsmÕte for fremstilling av sulfinylderivater ved oksydasjon av de tilsvarende CO-derivater med perborater | |
| DK188288A (da) | 1-phenyl-3-naphthalenyloxypropanaminer, fremgangsmaade til fremstilling af saadanne forbindelser og farmaceutiske midler indeholdende disse | |
| DK1038875T3 (da) | Imidazopyridine- derivativer og fremgangsmåde til fremstilling deraf | |
| NZ503912A (en) | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds and their use as substance P antagonists | |
| HUT53782A (en) | Fungicides comprising brackets open (trifluoromethyl)-phenyl brackets closed-(azolylmethyl)-oxirans and process for producing the active ingredients | |
| PL309874A1 (en) | Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives | |
| DE69022294D1 (de) | N-Heteroaryl-purin-6-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel. | |
| DK164915C (da) | Anvendelse af 17beta-methoxycarbonyl-4-aza-4-methyl-5alfa-androst-1-en-3-on til fremstilling af et topisk praeparat | |
| MY101042A (en) | Pyridazinone derivatives,process for preparation thereof, and insecticidal compotions | |
| AU3551884A (en) | Quinazoline and isoquinoline derivatives | |
| AU2274999A (en) | 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid derivatives as chelating agents | |
| NO994209L (no) | Fremgangsmaate for fremstilling av 2-ÄÄ(2-pyridinyl)metylÜsulfinylÜ-1H-benzimidazoler og nye forbindelser til anvendelse for dette formaal | |
| ATE62908T1 (de) | Neue derivate von 4,5-dihydro-oxazolen, verfahren zu ihrer herstellung und ihre verwendung. | |
| TR200402776T4 (tr) | Nöraminik asit bileşiğinin hidratları ve bunların kristal biçimleri. | |
| DE3781879D1 (de) | Anthracyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
| RU1771475C (ru) | Способ получени 6-бензилоксизамещенных изопропиловых эфиров @ -карболин-3-карбоновой кислоты | |
| AU1586588A (en) | Fungicidal derivatives of propenoic acid and processes for their preparation | |
| ES8800639A1 (es) | Un procedimiento para la preparacion de una hoja registradora. | |
| NO914192L (no) | 8-azabicyklo(3.2.1)oktylalkylthiazolidinoner, fremgangsmaate for fremstilling og anvendelse som medikamenter | |
| DK574582A (da) | (1,2)-kondenserede 1,4-benzodiazepin-forbindelser og fremgangsmaade til fremstilling deraf | |
| AU573062B2 (en) | Dihydrodithiazine derivatives | |
| DK0614890T3 (da) | Fremgangsmåde til fremstilling af eventuelt 2-substituerede 5-chlorimidazoler. | |
| JPS55154984A (en) | Novel 4-substituted-2h-1,3,2-oxaazaphospholine-2-oxide derivative |