[go: up one dir, main page]

NO20003890D0 - Glykosidering av 4,5-epoksymorfinan-6-oler - Google Patents

Glykosidering av 4,5-epoksymorfinan-6-oler

Info

Publication number
NO20003890D0
NO20003890D0 NO20003890A NO20003890A NO20003890D0 NO 20003890 D0 NO20003890 D0 NO 20003890D0 NO 20003890 A NO20003890 A NO 20003890A NO 20003890 A NO20003890 A NO 20003890A NO 20003890 D0 NO20003890 D0 NO 20003890D0
Authority
NO
Norway
Prior art keywords
epoxymorphinan
glycosidation
ols
thioglycoside
glucuronides
Prior art date
Application number
NO20003890A
Other languages
English (en)
Other versions
NO20003890L (no
Inventor
Arie Gutman
Genadi Nisnevitch
Lev Yudovitch
Igor Rochman
Original Assignee
Cenes Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12314998A external-priority patent/IL123149A0/xx
Priority claimed from IL12565298A external-priority patent/IL125652A0/xx
Application filed by Cenes Ltd filed Critical Cenes Ltd
Publication of NO20003890D0 publication Critical patent/NO20003890D0/no
Publication of NO20003890L publication Critical patent/NO20003890L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20003890A 1998-02-02 2000-07-28 Glykosidering av 4,5-epoksymorfinan-6-oler NO20003890L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL12314998A IL123149A0 (en) 1998-02-02 1998-02-02 Process for preparation of morphine-6-beta-d-glucoronide (M6G)
IL12565298A IL125652A0 (en) 1998-08-04 1998-08-04 Process for the glycosylation of 4,5-epoxymorphinanes using thioglycosides as glycoside donors
GB9900831 1999-01-15
PCT/GB1999/000336 WO1999038876A1 (en) 1998-02-02 1999-02-02 Glycosidation of 4,5-epoxymorphinan-6-ols

Publications (2)

Publication Number Publication Date
NO20003890D0 true NO20003890D0 (no) 2000-07-28
NO20003890L NO20003890L (no) 2000-09-21

Family

ID=27269616

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003890A NO20003890L (no) 1998-02-02 2000-07-28 Glykosidering av 4,5-epoksymorfinan-6-oler

Country Status (11)

Country Link
US (1) US6555665B1 (no)
EP (1) EP1053244B1 (no)
JP (1) JP2002506002A (no)
AT (1) ATE252593T1 (no)
AU (1) AU756816B2 (no)
CA (1) CA2319833A1 (no)
DE (1) DE69912245T2 (no)
HU (1) HUP0100841A3 (no)
NO (1) NO20003890L (no)
PL (1) PL342189A1 (no)
WO (1) WO1999038876A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9914382D0 (en) * 1999-06-21 1999-08-18 Ufc Limited New process for the manufacture of morphine-6-glucuronide and its analogues and also to a manufacture of new intermediaries
FR2939796B1 (fr) * 2008-12-11 2010-12-17 Sanofi Aventis Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique
CN103421063B (zh) * 2012-05-23 2016-04-06 宜昌人福药业有限责任公司 一种合成吗啡-6-β-D-葡萄糖醛酸苷的方法
CN106008621B (zh) * 2014-03-26 2019-02-19 宜昌人福药业有限责任公司 一种吗啡-6-β-D-葡萄糖醛酸苷的合成方法及其中间体化合物
CN108727444B (zh) * 2017-04-19 2020-10-23 宜昌人福药业有限责任公司 吗啡-6-β-D-葡萄糖醛酸苷的合成方法及其中间体化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9116909D0 (en) * 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
FR2680786B1 (fr) 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.

Also Published As

Publication number Publication date
CA2319833A1 (en) 1999-08-05
HUP0100841A2 (hu) 2001-09-28
PL342189A1 (en) 2001-05-21
EP1053244A1 (en) 2000-11-22
AU756816B2 (en) 2003-01-23
WO1999038876A1 (en) 1999-08-05
DE69912245T2 (de) 2004-07-29
NO20003890L (no) 2000-09-21
HUP0100841A3 (en) 2003-03-28
AU2433099A (en) 1999-08-16
EP1053244B1 (en) 2003-10-22
JP2002506002A (ja) 2002-02-26
US6555665B1 (en) 2003-04-29
ATE252593T1 (de) 2003-11-15
DE69912245D1 (de) 2003-11-27

Similar Documents

Publication Publication Date Title
SE9301677L (sv) Syntesmetod
CA2218246A1 (en) Enzymatic synthesis of glycosidic linkages
HU9401745D0 (en) Glycosylated steroid derivatives for transport across biological membranes and process for producing them
TR199900083T2 (xx) Klaritromisinin kristal bi�imi I.
ES2124373T3 (es) Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico.
EP0337256A3 (de) Verfahren zur Herstellung pharmazeutischer Mischungen
EP0505572A4 (en) Iridoide derivative and its use as medicine
NO930006D0 (no) Fremgangsmaate ved fremstilling av beta-laktamer
IL73521A0 (en) Preparation of intermediate compounds for the synthesis of nucleosides and certain such novel compounds
ES2122905A1 (es) Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
AU8321791A (en) Oligosaccharide mixture, and procedure for its manufacturing
AU8087087A (en) Process for the preparation of 5,6 dihydroxyindole and its 3-alkyl derivative; intermediate compounds and its nitrile intermediate compounds
AU584635B2 (en) Process for the preparation of 4-phenylpyrrole derivatives
GR81630B (no)
NO20003890L (no) Glykosidering av 4,5-epoksymorfinan-6-oler
AU8799491A (en) Process for the preparation of diethers
ES456574A1 (es) Procedimiento de obtencion de pentametil-carbamato de quer- cetina.
AU3901189A (en) Improved process for the conversion of daunorubicin into doxorubicin
FI890612L (fi) Menetelmä 4-demetoksidaunomysinonin, joka on 4-demetoksidaunorubisiinin aglykoni, valmistamiseksi
AU5069298A (en) Novel triterpene glycoside compound, process for preparation thereof and anti-cancer composition containing the same
AU2895797A (en) Carbohydrate derivatives and their solid-phase synthesis
MY103552A (en) Saccharide derivatives
AU6570294A (en) High piece of furniture supported by planar parts
DE3462257D1 (en) 4-amino-3-imidozolin-2-on and (2-methoxy-2-imino-ethyl) urea, their preparation and application
AU9139591A (en) Process for the preparation of bromonitro-alcohols, dibromonitro-alcohols and blends thereof

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application