NL2039643A - Mycosporine-like amino acids as nature's alternative to traditional sun filters - Google Patents
Mycosporine-like amino acids as nature's alternative to traditional sun filtersInfo
- Publication number
- NL2039643A NL2039643A NL2039643A NL2039643A NL2039643A NL 2039643 A NL2039643 A NL 2039643A NL 2039643 A NL2039643 A NL 2039643A NL 2039643 A NL2039643 A NL 2039643A NL 2039643 A NL2039643 A NL 2039643A
- Authority
- NL
- Netherlands
- Prior art keywords
- mycosporine
- amino acids
- nature
- alternative
- sun filters
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
Two biomimetic Mycosporine—Iike amino acids (MMAs), methoxyphenylimino dimethylcyclohexene ethyl glycinate and caprylyloxyphenylamino dimethyltetrahydro benzothiazine carboxylic acid, demonstrated broad-spectrum protection against both UVB and UVA.
Description
MYCOSPORINE-LIKE AMINO ACIDS AS NATURE'S ALTERNATIVE TO TRADITIONAL
SUN FILTERS
The escalating incidence of skin cancers and premature aging (photoaging) underscores the imperative for novel molecules possessing UV-absorbing capabilities.
Exploring ingredients with UV absorption capabilities to fortify the existing array of UV filters is beneficial. Historically, a limited number of ingredients have exhibited adequate efficacy in the UV spectral range.
Mycosporine-like amino acids (MAA) are relatively new molecules for cosmetics but have existed in nature for millions of years. They are produced by certain bacteria, microalgae or marine organisms to self-protect from the sun. Until now, the MAA came from the extraction from marine organisms or microalgae.
This study aimed to evaluate the potential UV sun protection and free radical neutralization properties of two biomimetic Mycosporine-like amino acids (MMAs), methoxyphenylimino dimethylcyclohexene ethyl glycinate (CAS Nr 2640340-86-7) and caprylyloxyphenylamino dimethyltetrahydro benzothiazine carboxylic acid (CAS Nr1629023- 01-3) exhibiting distinct absorption-spectrum profiles.
Various concentrations of Mycosporine-like amino acids were incorporated into a standard oil-in-water emulsion. The UV-absorbing spectrum, Sun Protection Factor (SPF), and Persistent Pigment Darkening (PPD or PFA) of each formulation were assessed using
ISO test methods 23675 and 24443. In vitro free radical protection was evaluated through a
DPPH test.
In the UVB spectral range, both tested MMAs demonstrated effectiveness comparable to many currently employed UVB filters. Their innovative chemical design conferred broad-spectrum protection against both UVB and UVA. Notably, a 1% dosage led to a 15% to 30% increase in both SPF and PFA. Furthermore, the DPPH test revealed that the two MMAs exhibited robust antioxidant properties.
Produced through an eco-friendly green chemistry process, the two tested MMAs showcased compelling properties by enhancing both SPF and UVA protection factors while displaying significant antioxidant potential. 1
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202463626810P | 2024-01-30 | 2024-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL2039643A true NL2039643A (en) | 2025-08-08 |
Family
ID=94768777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL2039643A NL2039643A (en) | 2024-01-30 | 2025-01-20 | Mycosporine-like amino acids as nature's alternative to traditional sun filters |
Country Status (1)
| Country | Link |
|---|---|
| NL (1) | NL2039643A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002039974A1 (en) * | 2000-11-17 | 2002-05-23 | Natural Environment Research Council | Personal care compositions |
-
2025
- 2025-01-20 NL NL2039643A patent/NL2039643A/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002039974A1 (en) * | 2000-11-17 | 2002-05-23 | Natural Environment Research Council | Personal care compositions |
Non-Patent Citations (5)
| Title |
|---|
| BHATIA SAURABH ET AL: "Mycosporine and mycosporine-like amino acids: A paramount tool against ultra violet irradiation", PHARMACOGNOSY REVIEWS, vol. 5, no. 10, 1 January 2011 (2011-01-01), India, pages 138, XP093028974, ISSN: 0973-7847, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263047/pdf/PRev-5-138.pdf> DOI: 10.4103/0973-7847.91107 * |
| DATABASE GNPD [online] MINTEL; 23 March 2010 (2010-03-23), ANONYMOUS: "SPF 30 PA+++ High Protection Tinted Face Lotion", XP093295370, retrieved from https://www.gnpd.com/sinatra/recordpage/1299164/ Database accession no. 1299164 * |
| no. 1629023-01-3 |
| PEDROSA VANESSA MD ET AL: "Production of mycosporine-like amino acid (MAA)-loaded emulsions as chemical barriers to control sunscald in fruits and vegetables", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 102, no. 2, 1 January 2022 (2022-01-01), GB, pages 801 - 812, XP093295374, ISSN: 0022-5142, DOI: 10.1002/jsfa.11415 * |
| YARKENT �AGLA ET AL: "Potential of microalgal compounds in trending natural cosmetics: A review", SUSTAINABLE CHEMISTRY AND PHARMACY, vol. 17, 1 September 2020 (2020-09-01), pages 100304, XP093150693, ISSN: 2352-5541, DOI: 10.1016/j.scp.2020.100304 * |
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