NL1003300C2 - Implanteerbare therapeutische inrichting. - Google Patents
Implanteerbare therapeutische inrichting. Download PDFInfo
- Publication number
- NL1003300C2 NL1003300C2 NL1003300A NL1003300A NL1003300C2 NL 1003300 C2 NL1003300 C2 NL 1003300C2 NL 1003300 A NL1003300 A NL 1003300A NL 1003300 A NL1003300 A NL 1003300A NL 1003300 C2 NL1003300 C2 NL 1003300C2
- Authority
- NL
- Netherlands
- Prior art keywords
- tube
- therapeutic
- cell
- layer
- therapeutic device
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title claims description 130
- 239000000463 material Substances 0.000 claims description 251
- -1 polytetrafluoroethylene Polymers 0.000 claims description 66
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 55
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 53
- 239000000017 hydrogel Substances 0.000 claims description 45
- 239000011148 porous material Substances 0.000 claims description 28
- 239000012530 fluid Substances 0.000 claims description 21
- 230000002792 vascular Effects 0.000 claims description 21
- 239000003795 chemical substances by application Substances 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 15
- 238000001415 gene therapy Methods 0.000 claims description 13
- 238000012377 drug delivery Methods 0.000 claims description 11
- 238000005259 measurement Methods 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 8
- 229940124597 therapeutic agent Drugs 0.000 claims description 8
- 235000010443 alginic acid Nutrition 0.000 claims description 5
- 229920000615 alginic acid Polymers 0.000 claims description 5
- 210000000056 organ Anatomy 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 4
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 3
- 108010035532 Collagen Proteins 0.000 claims description 3
- 102000008186 Collagen Human genes 0.000 claims description 3
- 239000004698 Polyethylene Substances 0.000 claims description 3
- 239000004743 Polypropylene Substances 0.000 claims description 3
- 229940072056 alginate Drugs 0.000 claims description 3
- 229920001436 collagen Polymers 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 229920000573 polyethylene Polymers 0.000 claims description 3
- 229920001155 polypropylene Polymers 0.000 claims description 3
- 229920000936 Agarose Polymers 0.000 claims description 2
- 102000008946 Fibrinogen Human genes 0.000 claims description 2
- 108010049003 Fibrinogen Proteins 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 2
- 239000002033 PVDF binder Substances 0.000 claims description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 2
- 239000000783 alginic acid Substances 0.000 claims description 2
- 229960001126 alginic acid Drugs 0.000 claims description 2
- 150000004781 alginic acids Chemical class 0.000 claims description 2
- 239000000679 carrageenan Substances 0.000 claims description 2
- 235000010418 carrageenan Nutrition 0.000 claims description 2
- 229920001525 carrageenan Polymers 0.000 claims description 2
- 229940113118 carrageenan Drugs 0.000 claims description 2
- 229960005188 collagen Drugs 0.000 claims description 2
- 229940012952 fibrinogen Drugs 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229940014259 gelatin Drugs 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 2
- 229940068984 polyvinyl alcohol Drugs 0.000 claims description 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 claims description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 2
- 229920002148 Gellan gum Polymers 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- 235000010492 gellan gum Nutrition 0.000 claims 1
- 239000000216 gellan gum Substances 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 109
- 229940058401 polytetrafluoroethylene Drugs 0.000 description 49
- 210000001519 tissue Anatomy 0.000 description 43
- 238000000034 method Methods 0.000 description 31
- 239000007788 liquid Substances 0.000 description 27
- 230000035699 permeability Effects 0.000 description 22
- 239000002861 polymer material Substances 0.000 description 21
- 210000004379 membrane Anatomy 0.000 description 19
- 239000012528 membrane Substances 0.000 description 19
- 238000002513 implantation Methods 0.000 description 16
- 238000007789 sealing Methods 0.000 description 12
- 239000007943 implant Substances 0.000 description 11
- 206010052428 Wound Diseases 0.000 description 8
- 208000027418 Wounds and injury Diseases 0.000 description 8
- 230000004907 flux Effects 0.000 description 8
- 238000002844 melting Methods 0.000 description 7
- 230000008018 melting Effects 0.000 description 7
- 229920001296 polysiloxane Polymers 0.000 description 7
- 239000005556 hormone Substances 0.000 description 6
- 229940088597 hormone Drugs 0.000 description 6
- 235000015097 nutrients Nutrition 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 210000002808 connective tissue Anatomy 0.000 description 5
- 238000005538 encapsulation Methods 0.000 description 5
- 238000001746 injection moulding Methods 0.000 description 5
- 238000001000 micrograph Methods 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 239000002699 waste material Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 4
- 239000005977 Ethylene Substances 0.000 description 4
- 230000000712 assembly Effects 0.000 description 4
- 238000000429 assembly Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 230000001419 dependent effect Effects 0.000 description 4
- 238000010030 laminating Methods 0.000 description 4
- 239000000565 sealant Substances 0.000 description 4
- 238000007920 subcutaneous administration Methods 0.000 description 4
- 210000003556 vascular endothelial cell Anatomy 0.000 description 4
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 3
- 241000282537 Mandrillus sphinx Species 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 206010029113 Neovascularisation Diseases 0.000 description 3
- 241000700159 Rattus Species 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 244000273618 Sphenoclea zeylanica Species 0.000 description 3
- 239000002870 angiogenesis inducing agent Substances 0.000 description 3
- 239000003181 biological factor Substances 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000011737 fluorine Substances 0.000 description 3
- 229910052731 fluorine Inorganic materials 0.000 description 3
- 238000010562 histological examination Methods 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 210000000265 leukocyte Anatomy 0.000 description 3
- 230000001050 lubricating effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 3
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 241000894007 species Species 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000007858 starting material Substances 0.000 description 3
- 229940126585 therapeutic drug Drugs 0.000 description 3
- 229920001169 thermoplastic Polymers 0.000 description 3
- 239000004416 thermosoftening plastic Substances 0.000 description 3
- 238000004804 winding Methods 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 description 2
- 239000004215 Carbon black (E152) Substances 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 108090000695 Cytokines Proteins 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 102000018233 Fibroblast Growth Factor Human genes 0.000 description 2
- 108050007372 Fibroblast Growth Factor Proteins 0.000 description 2
- 102100031372 Thymidine phosphorylase Human genes 0.000 description 2
- 108700023160 Thymidine phosphorylases Proteins 0.000 description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 description 2
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 2
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 description 2
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
- 230000003187 abdominal effect Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000004873 anchoring Methods 0.000 description 2
- 230000033115 angiogenesis Effects 0.000 description 2
- 230000002491 angiogenic effect Effects 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Substances [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 230000012085 chronic inflammatory response Effects 0.000 description 2
- 239000003433 contraceptive agent Substances 0.000 description 2
- 230000002254 contraceptive effect Effects 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 2
- 210000003372 endocrine gland Anatomy 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 229940126864 fibroblast growth factor Drugs 0.000 description 2
- 210000004907 gland Anatomy 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 238000011068 loading method Methods 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 239000002953 phosphate buffered saline Substances 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- 101150028074 2 gene Proteins 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical class [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229910000531 Co alloy Inorganic materials 0.000 description 1
- 229910000599 Cr alloy Inorganic materials 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 241000143637 Eleocharis confervoides Species 0.000 description 1
- 229920002449 FKM Polymers 0.000 description 1
- 102100037362 Fibronectin Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 108010085895 Laminin Proteins 0.000 description 1
- 102000007547 Laminin Human genes 0.000 description 1
- 229920000459 Nitrile rubber Polymers 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000000735 allogeneic effect Effects 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 210000003567 ascitic fluid Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000008512 biological response Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000005388 borosilicate glass Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical class [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 1
- 235000011132 calcium sulphate Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 239000000788 chromium alloy Substances 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003989 endothelium vascular Anatomy 0.000 description 1
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 239000004811 fluoropolymer Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 108010038983 glycyl-histidyl-lysine Proteins 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 208000028867 ischemia Diseases 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 230000003137 locomotive effect Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 108010082117 matrigel Proteins 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 210000003200 peritoneal cavity Anatomy 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 229910001392 phosphorus oxide Inorganic materials 0.000 description 1
- LFGREXWGYUGZLY-UHFFFAOYSA-N phosphoryl Chemical class [P]=O LFGREXWGYUGZLY-UHFFFAOYSA-N 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
- 239000002952 polymeric resin Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- LIVNPJMFVYWSIS-UHFFFAOYSA-N silicon monoxide Chemical class [Si-]#[O+] LIVNPJMFVYWSIS-UHFFFAOYSA-N 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- VGTPCRGMBIAPIM-UHFFFAOYSA-M sodium thiocyanate Chemical compound [Na+].[S-]C#N VGTPCRGMBIAPIM-UHFFFAOYSA-M 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0004—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Transplantation (AREA)
- Dispersion Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48225095A | 1995-06-07 | 1995-06-07 | |
| US48225095 | 1995-06-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL1003300A1 NL1003300A1 (nl) | 1996-12-10 |
| NL1003300C2 true NL1003300C2 (nl) | 1997-03-20 |
Family
ID=23915336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1003300A NL1003300C2 (nl) | 1995-06-07 | 1996-06-07 | Implanteerbare therapeutische inrichting. |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5913998A (fr) |
| EP (1) | EP0773753B1 (fr) |
| JP (1) | JPH10503964A (fr) |
| AU (1) | AU6251196A (fr) |
| CA (1) | CA2190628C (fr) |
| DE (1) | DE69630266T2 (fr) |
| FR (1) | FR2735032B1 (fr) |
| NL (1) | NL1003300C2 (fr) |
| WO (1) | WO1996039993A1 (fr) |
Families Citing this family (308)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6331188B1 (en) | 1994-08-31 | 2001-12-18 | Gore Enterprise Holdings, Inc. | Exterior supported self-expanding stent-graft |
| US6015429A (en) | 1994-09-08 | 2000-01-18 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
| EP0773753B1 (fr) * | 1995-06-07 | 2003-10-08 | Gore Hybrid Technologies, Inc. | Appareil de confinement implantable destine a un dispositif therapeutque |
| US6042605A (en) | 1995-12-14 | 2000-03-28 | Gore Enterprose Holdings, Inc. | Kink resistant stent-graft |
| JP2000503559A (ja) | 1995-12-14 | 2000-03-28 | ゴア エンタープライズ ホールディングス，インコーポレイティド | ステント移植片を展開する装置並びに方法 |
| US6306491B1 (en) * | 1996-12-20 | 2001-10-23 | Gore Enterprise Holdings, Inc. | Respiratory aids |
| NZ336455A (en) | 1996-12-20 | 2001-04-27 | Usf Filtration & Separations | A method for cleaning porous membranes using a gas bubble system |
| US6551350B1 (en) | 1996-12-23 | 2003-04-22 | Gore Enterprise Holdings, Inc. | Kink resistant bifurcated prosthesis |
| US6352561B1 (en) | 1996-12-23 | 2002-03-05 | W. L. Gore & Associates | Implant deployment apparatus |
| US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US7657297B2 (en) * | 2004-05-03 | 2010-02-02 | Dexcom, Inc. | Implantable analyte sensor |
| US20050033132A1 (en) | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US6117643A (en) * | 1997-11-25 | 2000-09-12 | Ut Battelle, Llc | Bioluminescent bioreporter integrated circuit |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6533766B1 (en) * | 1998-07-24 | 2003-03-18 | Therox, Inc. | Coating medical device surfaces for delivering gas-supersaturated fluids |
| US6432126B1 (en) * | 1998-09-30 | 2002-08-13 | C.R. Bard, Inc. | Flexible vascular inducing implants |
| US8177762B2 (en) | 1998-12-07 | 2012-05-15 | C. R. Bard, Inc. | Septum including at least one identifiable feature, access ports including same, and related methods |
| WO2000033901A1 (fr) * | 1998-12-07 | 2000-06-15 | Std Manufacturing, Inc. | Dispositif d'acces vasculaire implantable |
| US6955661B1 (en) * | 1999-01-25 | 2005-10-18 | Atrium Medical Corporation | Expandable fluoropolymer device for delivery of therapeutic agents and method of making |
| US6884427B1 (en) * | 1999-02-08 | 2005-04-26 | Aderans Research Institute, Inc. | Filamentary means for introducing agents into tissue of a living host |
| US6468264B1 (en) * | 1999-10-12 | 2002-10-22 | Durect Corporation | Closed exchange system |
| EP1690527B1 (fr) * | 1999-11-17 | 2015-01-07 | Boston Scientific Limited | Dispositifs microfabriques pour transport de molécules dans un fluide porteur |
| US6520997B1 (en) | 1999-12-08 | 2003-02-18 | Baxter International Inc. | Porous three dimensional structure |
| CA2361930A1 (fr) | 1999-12-08 | 2001-06-14 | Baxter International Inc. | Membrane filtrante microporeuse, procede de fabrication et separateur utilisant de telles membranes |
| US20030168396A1 (en) * | 1999-12-08 | 2003-09-11 | Jacobson James D. | Monolithic filter body and fabrication technique |
| US6982058B2 (en) * | 1999-12-08 | 2006-01-03 | Baxter International, Inc. | Method for fabricating three dimensional structures |
| US6479066B1 (en) | 1999-12-16 | 2002-11-12 | Rst Implanted Cell Technology, Llc | Device having a microporous membrane lined deformable wall for implanting cell cultures |
| US6283949B1 (en) | 1999-12-27 | 2001-09-04 | Advanced Cardiovascular Systems, Inc. | Refillable implantable drug delivery pump |
| US6617151B1 (en) | 2000-02-29 | 2003-09-09 | Gore Enterprise Holdings, Inc. | Method of closing a cell containment device with a wet seal |
| US6810880B1 (en) | 2000-04-10 | 2004-11-02 | Gore Enterprise Holdings, Inc. | Surgical implant system |
| US6962577B2 (en) * | 2000-04-26 | 2005-11-08 | Std Manufacturing, Inc. | Implantable hemodialysis access device |
| AU7920901A (en) * | 2000-08-08 | 2002-03-04 | Bioamide Inc | Scaffolds for tissue engineered hair |
| US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| EP1397068A2 (fr) | 2001-04-02 | 2004-03-17 | Therasense, Inc. | Dispositif et procede de recherche de glucose dans le sang |
| AUPR421501A0 (en) | 2001-04-04 | 2001-05-03 | U.S. Filter Wastewater Group, Inc. | Potting method |
| US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US6702857B2 (en) | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
| AUPR692401A0 (en) | 2001-08-09 | 2001-08-30 | U.S. Filter Wastewater Group, Inc. | Method of cleaning membrane modules |
| US20040068284A1 (en) * | 2002-01-29 | 2004-04-08 | Barrows Thomas H. | Method for stimulating hair growth and kit for carrying out said method |
| EP2034009B1 (fr) | 2002-02-08 | 2014-01-15 | Life Technologies Corporation | Compositions et procedes de restauration de reponse immunitaire chez des patients souffrant de deficiences immunologiques basant sur cd3/cd28 costimulation |
| US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
| US9282925B2 (en) | 2002-02-12 | 2016-03-15 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US7828728B2 (en) | 2003-07-25 | 2010-11-09 | Dexcom, Inc. | Analyte sensor |
| US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
| US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US7247238B2 (en) | 2002-02-12 | 2007-07-24 | Siemens Water Technologies Corp. | Poly(ethylene chlorotrifluoroethylene) membranes |
| US20030176797A1 (en) * | 2002-03-12 | 2003-09-18 | Fernando Anzellini | Thrombust; implantable delivery system sensible to self diagnosis of acute myocardial infarction for thrombolysis in the first minutes of chest pain |
| US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
| US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US8145316B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US6978174B2 (en) * | 2002-04-08 | 2005-12-20 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US7853333B2 (en) | 2002-04-08 | 2010-12-14 | Ardian, Inc. | Methods and apparatus for multi-vessel renal neuromodulation |
| US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US9308044B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| US8774922B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods |
| US8145317B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
| US7620451B2 (en) | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
| US8131371B2 (en) | 2002-04-08 | 2012-03-06 | Ardian, Inc. | Methods and apparatus for monopolar renal neuromodulation |
| US9308043B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US20060206150A1 (en) | 2002-04-08 | 2006-09-14 | Ardian, Inc. | Methods and apparatus for treating acute myocardial infarction |
| US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
| US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
| US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US7162303B2 (en) | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
| US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
| US9636174B2 (en) | 2002-04-08 | 2017-05-02 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| GB2389791B (en) * | 2002-04-30 | 2006-12-13 | Steven Gill | Implantable drug delivery pump |
| US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
| US6568177B1 (en) * | 2002-06-04 | 2003-05-27 | Ford Global Technologies, Llc | Method for rapid catalyst heating |
| AUPS300602A0 (en) * | 2002-06-18 | 2002-07-11 | U.S. Filter Wastewater Group, Inc. | Methods of minimising the effect of integrity loss in hollow fibre membrane modules |
| AU2003253684A1 (en) | 2002-06-28 | 2004-01-19 | Xcyte Therapies, Inc. | Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| KR101002466B1 (ko) | 2002-10-10 | 2010-12-17 | 지멘스 워터 테크놀로지스 코포레이션 | 역세척 방법 |
| AU2002953111A0 (en) | 2002-12-05 | 2002-12-19 | U. S. Filter Wastewater Group, Inc. | Mixing chamber |
| US7134999B2 (en) | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
| US20040220534A1 (en) * | 2003-04-29 | 2004-11-04 | Martens Paul W. | Medical device with antimicrobial layer |
| DK1623017T3 (da) * | 2003-05-08 | 2011-01-10 | Life Technologies Corp | Frembringelse og isolering af antigenspecifikke T-celler |
| US7875293B2 (en) | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
| JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
| WO2007120442A2 (fr) | 2003-07-25 | 2007-10-25 | Dexcom, Inc. | Système d'électrode double pour capteur d'analyte continu |
| US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US20100168657A1 (en) | 2003-08-01 | 2010-07-01 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
| US7925321B2 (en) | 2003-08-01 | 2011-04-12 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8761856B2 (en) | 2003-08-01 | 2014-06-24 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US8369919B2 (en) | 2003-08-01 | 2013-02-05 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US8886273B2 (en) | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7494465B2 (en) | 2004-07-13 | 2009-02-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7519408B2 (en) | 2003-11-19 | 2009-04-14 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
| US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8060173B2 (en) | 2003-08-01 | 2011-11-15 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| JP4611982B2 (ja) | 2003-08-29 | 2011-01-12 | シーメンス・ウォーター・テクノロジーズ・コーポレーション | 逆洗方法 |
| SE526959C2 (sv) * | 2003-10-02 | 2005-11-29 | Tikomed Ab | Bioartificellt implantat innefattande en semipermeabel barriär samt förfarande för reducering av risken för bildning av bindrväv vid implantatet efter implantering genom att barriären förses med en permeabel beläggning av bioaktiv metall |
| US8808540B2 (en) | 2003-11-14 | 2014-08-19 | Evoqua Water Technologies Llc | Module cleaning method |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8615282B2 (en) | 2004-07-13 | 2013-12-24 | Dexcom, Inc. | Analyte sensor |
| US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8774886B2 (en) | 2006-10-04 | 2014-07-08 | Dexcom, Inc. | Analyte sensor |
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| EP2239566B1 (fr) | 2003-12-05 | 2014-04-23 | DexCom, Inc. | Techniques d'étalonnage pour capteur d'analytes en continu |
| US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor |
| EP2301428B1 (fr) | 2003-12-09 | 2016-11-30 | Dexcom, Inc. | Traitement de signal pour capteur d'analyte continu |
| JP5132153B2 (ja) * | 2003-12-30 | 2013-01-30 | ボストン サイエンティフィック リミテッド | フッ素重合体生成物の一軸延伸法 |
| US7637868B2 (en) | 2004-01-12 | 2009-12-29 | Dexcom, Inc. | Composite material for implantable device |
| US7803178B2 (en) | 2004-01-30 | 2010-09-28 | Trivascular, Inc. | Inflatable porous implants and methods for drug delivery |
| WO2005079257A2 (fr) * | 2004-02-12 | 2005-09-01 | Dexcom, Inc. | Interface biologique avec macro- et micro-architecture |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US7597885B2 (en) * | 2004-03-26 | 2009-10-06 | Aderans Research Institute, Inc. | Tissue engineered biomimetic hair follicle graft |
| US8758621B2 (en) | 2004-03-26 | 2014-06-24 | Evoqua Water Technologies Llc | Process and apparatus for purifying impure water using microfiltration or ultrafiltration in combination with reverse osmosis |
| US8377110B2 (en) * | 2004-04-08 | 2013-02-19 | Endologix, Inc. | Endolumenal vascular prosthesis with neointima inhibiting polymeric sleeve |
| EP2380854A3 (fr) | 2004-04-22 | 2012-07-04 | Siemens Industry, Inc. | Appareil de filtration comprenant un bioréacteur à membrane et une cuve de traitement pour digérer les matières organiques |
| US8792955B2 (en) | 2004-05-03 | 2014-07-29 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8277713B2 (en) | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
| US20050245799A1 (en) * | 2004-05-03 | 2005-11-03 | Dexcom, Inc. | Implantable analyte sensor |
| US7968250B2 (en) * | 2004-06-25 | 2011-06-28 | Ultracell Corporation | Fuel cartridge connectivity |
| US7811266B2 (en) * | 2004-07-13 | 2010-10-12 | Std Med, Inc. | Volume reducing reservoir insert for an infusion port |
| US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
| US9414777B2 (en) | 2004-07-13 | 2016-08-16 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20070045902A1 (en) | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor |
| US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
| EP3417895A1 (fr) | 2004-07-28 | 2018-12-26 | Medtronic Ardian Luxembourg S.à.r.l. | Procédés et dispositifs pour le blocage du nerf rénal |
| AR050212A1 (es) * | 2004-08-13 | 2006-10-04 | Aderans Res Inst Inc | Organogenesis a partir de celulas disociadas |
| CN101052457B (zh) | 2004-08-20 | 2012-07-04 | 西门子工业公司 | 正方形mbr歧管系统 |
| US8790515B2 (en) | 2004-09-07 | 2014-07-29 | Evoqua Water Technologies Llc | Reduction of backwash liquid waste |
| WO2006029456A1 (fr) | 2004-09-14 | 2006-03-23 | Siemens Water Technologies Corp. | Procedes et appareil permettant d'eliminer des solides d'un module membranaire |
| NZ553771A (en) | 2004-09-15 | 2010-11-26 | Siemens Water Tech Corp | Continuously variable aeration of membrane filtration system and flow control device when used in such application |
| US7937143B2 (en) | 2004-11-02 | 2011-05-03 | Ardian, Inc. | Methods and apparatus for inducing controlled renal neuromodulation |
| US7591950B2 (en) | 2004-11-02 | 2009-09-22 | Siemens Water Technologies Corp. | Submerged cross-flow filtration |
| US9788978B2 (en) * | 2004-12-20 | 2017-10-17 | Nicholas A. Rojo | Implantable systems and stents containing cells for therapeutic uses |
| EP1838422A4 (fr) | 2004-12-24 | 2009-09-02 | Siemens Water Tech Corp | Procede et appareil simples de lavage au gaz |
| NZ555856A (en) | 2004-12-24 | 2010-03-26 | Siemens Water Tech Corp | Cleaning in membrane filtration systems |
| US9474888B2 (en) | 2005-03-04 | 2016-10-25 | C. R. Bard, Inc. | Implantable access port including a sandwiched radiopaque insert |
| US8029482B2 (en) | 2005-03-04 | 2011-10-04 | C. R. Bard, Inc. | Systems and methods for radiographically identifying an access port |
| US7947022B2 (en) | 2005-03-04 | 2011-05-24 | C. R. Bard, Inc. | Access port identification systems and methods |
| US9320831B2 (en) * | 2005-03-04 | 2016-04-26 | W. L. Gore & Associates, Inc. | Polymer shrink tubes and novel uses therefor |
| JP5484674B2 (ja) | 2005-03-04 | 2014-05-07 | シー・アール・バード・インコーポレーテッド | アクセスポートおよびその識別方法 |
| US8744546B2 (en) | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
| US20060233990A1 (en) | 2005-04-13 | 2006-10-19 | Trivascular, Inc. | PTFE layers and methods of manufacturing |
| US20060233991A1 (en) | 2005-04-13 | 2006-10-19 | Trivascular, Inc. | PTFE layers and methods of manufacturing |
| EP2324880B1 (fr) | 2005-04-27 | 2014-12-24 | C.R. Bard, Inc. | Appareils de perfuseur avec septum |
| WO2006116613A1 (fr) | 2005-04-27 | 2006-11-02 | C.R. Bard, Inc. | Appareils de perfusion |
| US10307581B2 (en) | 2005-04-27 | 2019-06-04 | C. R. Bard, Inc. | Reinforced septum for an implantable medical device |
| CN101184548B (zh) | 2005-04-29 | 2011-10-05 | 西门子水技术公司 | 用于膜滤器的化学清洗剂 |
| SG140229A1 (en) | 2005-08-22 | 2008-03-28 | Siemens Water Tech Corp | An assembly for water filtration using a tube manifold to minimise backwash |
| KR100756411B1 (ko) * | 2005-09-08 | 2007-09-10 | 삼성전자주식회사 | 열압착 공구 및 이를 포함한 열압착 장치 |
| US20070078416A1 (en) * | 2005-10-04 | 2007-04-05 | Kenneth Eliasen | Two-piece inline vascular access portal |
| WO2007044415A2 (fr) | 2005-10-05 | 2007-04-19 | Siemens Water Technologies Corp. | Procédé et appareil destinés à traiter les eaux usées |
| US7563363B2 (en) | 2005-10-05 | 2009-07-21 | Siemens Water Technologies Corp. | System for treating wastewater |
| MX2008004928A (es) * | 2005-10-17 | 2008-09-12 | Aderans Res Inst Inc | Metodo para suministrar celulas progenitoras de foliculo piloso a la piel. |
| CN101511303A (zh) * | 2005-11-21 | 2009-08-19 | 尼卡斯特有限公司 | 用于细胞移植的装置和方法 |
| AR057628A1 (es) * | 2005-11-22 | 2007-12-05 | Aderans Res Inst Inc | Injertos capilares derivados de cabello extirpado |
| TW200800240A (en) * | 2005-11-22 | 2008-01-01 | Aderans Res Inst Inc | Hair follicle graft from tissue engineered skin |
| US8197441B2 (en) | 2005-12-06 | 2012-06-12 | Abbott Cardiovascular Systems Inc. | Catheter mounted automatic vessel occlusion and fluid dispersion devices |
| US7455765B2 (en) | 2006-01-25 | 2008-11-25 | Siemens Water Technologies Corp. | Wastewater treatment system and method |
| EP1991110B1 (fr) | 2006-03-09 | 2018-11-07 | DexCom, Inc. | Systèmes et procédés de traitement de données de capteur de substance à analyser |
| US20080064937A1 (en) | 2006-06-07 | 2008-03-13 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
| US8021324B2 (en) | 2007-07-19 | 2011-09-20 | Medical Components, Inc. | Venous access port assembly with X-ray discernable indicia |
| WO2008051546A2 (fr) | 2006-10-24 | 2008-05-02 | Siemens Water Technologies Corp. | Régulation d'infiltration/débit entrant pour bioréacteur à membrane |
| US9642986B2 (en) | 2006-11-08 | 2017-05-09 | C. R. Bard, Inc. | Resource information key for an insertable medical device |
| US9265912B2 (en) | 2006-11-08 | 2016-02-23 | C. R. Bard, Inc. | Indicia informative of characteristics of insertable medical devices |
| US8734730B2 (en) * | 2007-03-30 | 2014-05-27 | Covidien Lp | Surgical instrument debris collection system |
| CA2682707C (fr) | 2007-04-02 | 2014-07-15 | Siemens Water Technologies Corp. | Commande d'infiltration/afflux amelioree pour bioreacteur a membranes |
| US9764288B2 (en) | 2007-04-04 | 2017-09-19 | Evoqua Water Technologies Llc | Membrane module protection |
| US20200037874A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| KR101625172B1 (ko) | 2007-05-29 | 2016-05-27 | 에보쿠아 워터 테크놀로지스 엘엘씨 | 수처리 시스템 |
| CA2688184A1 (fr) | 2007-06-08 | 2008-12-18 | Dexcom, Inc. | Dispositif de distribution de medicament integre pour une utilisation avec un capteur de substance a analyser en continu |
| US7985537B2 (en) * | 2007-06-12 | 2011-07-26 | Aderans Research Institute, Inc. | Methods for determining the hair follicle inductive properties of a composition |
| EP3269417B1 (fr) | 2007-06-20 | 2025-09-24 | Medical Components, Inc. | Port d'accès implantable avec indices moulés et/ou radio-opaques |
| WO2009012395A1 (fr) | 2007-07-19 | 2009-01-22 | Innovative Medical Devices, Llc | Ensemble orifice d'accès veineux avec indices discernables par rayons x |
| EP4098177A1 (fr) | 2007-10-09 | 2022-12-07 | DexCom, Inc. | Système d'administration d'insuline intégré avec un capteur de glucose en continu |
| AU2007360082B2 (en) * | 2007-10-11 | 2013-01-10 | Ah San Pang | A device for tube feeding |
| US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US9579496B2 (en) | 2007-11-07 | 2017-02-28 | C. R. Bard, Inc. | Radiopaque and septum-based indicators for a multi-lumen implantable port |
| US20090196854A1 (en) * | 2008-02-04 | 2009-08-06 | Kytos Biosystems S.A. | Methods and compositions for use of crl 5803 cells for expression of biotherapeutics and encapsulated cell-based delivery |
| US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| EP2331242B1 (fr) | 2008-07-24 | 2018-09-05 | Evoqua Water Technologies LLC | Système de cadre pour modules de filtration sur membrane |
| US8105308B2 (en) * | 2008-08-02 | 2012-01-31 | Ghodsian Laboratories, Inc. | Permanent umbilical hollow tube |
| EP2315625B1 (fr) | 2008-08-20 | 2018-05-16 | Evoqua Water Technologies LLC | Rendement énergétique amélioré du lavage à contre-courant d'un système à membrane |
| US20100080784A1 (en) * | 2008-09-12 | 2010-04-01 | Torrey Pines Institute For Molecular Studies | Methods for treating cachexia and lymphopenia |
| US8560039B2 (en) | 2008-09-19 | 2013-10-15 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
| EP2346553B1 (fr) | 2008-10-31 | 2022-01-19 | C.R. Bard, Inc. | Systèmes et procédés d'identification d'un orifice d'accès |
| JP4944864B2 (ja) * | 2008-11-04 | 2012-06-06 | 日東電工株式会社 | ポリテトラフルオロエチレン多孔質膜およびその製造方法ならびに防水通気フィルタ |
| US11890443B2 (en) | 2008-11-13 | 2024-02-06 | C. R. Bard, Inc. | Implantable medical devices including septum-based indicators |
| US8932271B2 (en) | 2008-11-13 | 2015-01-13 | C. R. Bard, Inc. | Implantable medical devices including septum-based indicators |
| EP3363444B1 (fr) | 2008-11-14 | 2022-09-14 | ViaCyte, Inc. | Encapsulation de cellules pancréatiques dérivées de cellules souches pluripotentes humaines |
| US8652129B2 (en) | 2008-12-31 | 2014-02-18 | Medtronic Ardian Luxembourg S.A.R.L. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
| WO2010111660A1 (fr) | 2009-03-27 | 2010-09-30 | Dexcom, Inc. | Procédés et systèmes favorisant la gestion du glucose |
| US8627867B2 (en) * | 2009-04-21 | 2014-01-14 | Bae Systems Information And Electronic Systems Integration Inc. | System and method for microelectronics lamination press |
| WO2010142673A1 (fr) | 2009-06-11 | 2010-12-16 | Siemens Water Technologies Corp. | Procédés de nettoyage d'une membrane polymère poreuse et kit pour le nettoyage d'une membrane polymère poreuse |
| US8715244B2 (en) | 2009-07-07 | 2014-05-06 | C. R. Bard, Inc. | Extensible internal bolster for a medical device |
| AU2010286531B2 (en) | 2009-08-28 | 2014-02-06 | Sernova Corporation | Methods and devices for cellular transplantation |
| WO2011062750A1 (fr) | 2009-11-17 | 2011-05-26 | C. R. Bard, Inc. | Orifice d'accès surmoulé comprenant des caractéristiques d'ancrage et d'identification |
| US8377034B2 (en) | 2009-12-04 | 2013-02-19 | Std Med, Inc. | Vascular access port |
| HUE045642T2 (hu) | 2010-04-30 | 2020-01-28 | Evoqua Water Tech Llc | Folyadékáramlás elosztó készülék |
| US9023095B2 (en) * | 2010-05-27 | 2015-05-05 | Idev Technologies, Inc. | Stent delivery system with pusher assembly |
| US9475709B2 (en) | 2010-08-25 | 2016-10-25 | Lockheed Martin Corporation | Perforated graphene deionization or desalination |
| WO2012040412A1 (fr) | 2010-09-24 | 2012-03-29 | Siemens Industry, Inc. | Collecteur de commande de fluide pour système de filtration à membrane |
| WO2012061153A1 (fr) | 2010-10-25 | 2012-05-10 | Medtronic Ardian Luxembourg S.A.R.L. | Dispositifs, systèmes et procédés d'évaluation et de retour d'informations de traitement de neuromodulation |
| USD682416S1 (en) | 2010-12-30 | 2013-05-14 | C. R. Bard, Inc. | Implantable access port |
| USD676955S1 (en) | 2010-12-30 | 2013-02-26 | C. R. Bard, Inc. | Implantable access port |
| WO2012115619A1 (fr) * | 2011-02-21 | 2012-08-30 | Viacyte, Inc. | Système de chargement pour un dispositif d'encapsulation |
| ES2847578T3 (es) | 2011-04-15 | 2021-08-03 | Dexcom Inc | Calibración avanzada de sensor de analito y detección de errores |
| AU2013200833B2 (en) | 2011-09-30 | 2015-09-17 | Evoqua Water Technologies Llc | Improved manifold arrangement |
| CA2850522C (fr) | 2011-09-30 | 2021-03-16 | Evoqua Water Technologies Llc | Vanne d'arret servant a isoler un module de filtre a membrane a fibre creuse |
| WO2013078230A1 (fr) | 2011-11-23 | 2013-05-30 | The Trustees Of The University Of Pennsylvania | Utilisation de cellules exprimant pdl1 pour convertir des lymphocytes t en lymphocytes t régulateurs |
| CN104271062B (zh) | 2012-03-08 | 2017-07-07 | 美敦力Af卢森堡有限责任公司 | 采用神经调节装置的生物标志物取样和相关系统及方法 |
| AU2013230781B2 (en) | 2012-03-08 | 2015-12-03 | Medtronic Af Luxembourg S.A.R.L. | Ovarian neuromodulation and associated systems and methods |
| US9834809B2 (en) | 2014-02-28 | 2017-12-05 | Lockheed Martin Corporation | Syringe for obtaining nano-sized materials for selective assays and related methods of use |
| US10017852B2 (en) | 2016-04-14 | 2018-07-10 | Lockheed Martin Corporation | Method for treating graphene sheets for large-scale transfer using free-float method |
| US10653824B2 (en) | 2012-05-25 | 2020-05-19 | Lockheed Martin Corporation | Two-dimensional materials and uses thereof |
| US10980919B2 (en) | 2016-04-14 | 2021-04-20 | Lockheed Martin Corporation | Methods for in vivo and in vitro use of graphene and other two-dimensional materials |
| US9744617B2 (en) | 2014-01-31 | 2017-08-29 | Lockheed Martin Corporation | Methods for perforating multi-layer graphene through ion bombardment |
| US10376845B2 (en) | 2016-04-14 | 2019-08-13 | Lockheed Martin Corporation | Membranes with tunable selectivity |
| KR102108593B1 (ko) | 2012-06-28 | 2020-05-29 | 에보쿠아 워터 테크놀로지스 엘엘씨 | 포팅 방법 |
| US9962865B2 (en) | 2012-09-26 | 2018-05-08 | Evoqua Water Technologies Llc | Membrane potting methods |
| DE112013004713T5 (de) | 2012-09-26 | 2015-07-23 | Evoqua Water Technologies Llc | Membransicherungsvorrichtung |
| EP2900356A1 (fr) | 2012-09-27 | 2015-08-05 | Evoqua Water Technologies LLC | Appareil de décapage à gaz pour membranes immergées |
| US20140110296A1 (en) | 2012-10-19 | 2014-04-24 | Medtronic Ardian Luxembourg S.A.R.L. | Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods |
| EP2948121B1 (fr) | 2013-01-23 | 2017-11-29 | C.R. Bard Inc. | Orifice d'accès surbaissé |
| US11420033B2 (en) | 2013-01-23 | 2022-08-23 | C. R. Bard, Inc. | Low-profile single and dual vascular access device |
| US11464960B2 (en) | 2013-01-23 | 2022-10-11 | C. R. Bard, Inc. | Low-profile single and dual vascular access device |
| PL2964147T3 (pl) * | 2013-03-07 | 2018-10-31 | Viacyte, Inc. | Trójwymiarowy zestaw urządzeń o dużej pojemności do kapsułkowania komórek |
| US9592475B2 (en) | 2013-03-12 | 2017-03-14 | Lockheed Martin Corporation | Method for forming perforated graphene with uniform aperture size |
| EP2971039B1 (fr) | 2013-03-14 | 2020-01-01 | Immusoft Corporation | Procédé de différentiation et de transduction in vitro de lymphocytes b à mémoire avec des vecteurs viraux pseudotypés vsv-g |
| US9572918B2 (en) | 2013-06-21 | 2017-02-21 | Lockheed Martin Corporation | Graphene-based filter for isolating a substance from blood |
| HUE061765T2 (hu) | 2013-10-02 | 2023-08-28 | Rohm & Haas Electronic Mat Singapore Pte Ltd | Berendezés membrán filtrációs modul javítására |
| KR20160142820A (ko) | 2014-01-31 | 2016-12-13 | 록히드 마틴 코포레이션 | 브로드 이온 필드를 사용한 2차원 물질 천공 |
| AU2015210875A1 (en) | 2014-01-31 | 2016-09-15 | Lockheed Martin Corporation | Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer |
| CN106232205A (zh) | 2014-03-12 | 2016-12-14 | 洛克希德马丁公司 | 由有孔石墨烯形成的分离膜 |
| US10194979B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| US10194980B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| US9980766B1 (en) | 2014-03-28 | 2018-05-29 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and systems for renal neuromodulation |
| US10369345B2 (en) | 2014-03-31 | 2019-08-06 | Versago Vascular Access, Inc. | Medical access port, systems and methods of use thereof |
| US9764124B2 (en) | 2014-03-31 | 2017-09-19 | Versago Vascular Access, Inc. | Vascular access port |
| AU2015240568B2 (en) | 2014-04-03 | 2019-08-22 | Versago Vascular Access, Inc. | Devices and methods for installation and removal of a needle tip of a needle |
| CN106573133B (zh) | 2014-08-19 | 2020-03-03 | 加利福尼亚大学董事会 | 用于局部药物递送的植入物及其使用方法 |
| CN107073408A (zh) | 2014-09-02 | 2017-08-18 | 洛克希德马丁公司 | 基于二维膜材料的血液透析膜和血液过滤膜及其应用方法 |
| EP3206567A1 (fr) | 2014-10-13 | 2017-08-23 | Glusense, Ltd. | Dispositif de détection d'analyte |
| KR102583138B1 (ko) | 2014-10-31 | 2023-09-26 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | T 세포를 자극 및 증대시키는 조성물 및 방법 |
| EP4427809A3 (fr) | 2014-10-31 | 2024-12-04 | The Trustees of The University of Pennsylvania | Modification de l'expression genique dans des cellules car-t et utilisations correspondantes |
| KR20170074243A (ko) | 2014-10-31 | 2017-06-29 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 변형된 t 세포의 생성 방법 및 조성물 |
| WO2016100868A1 (fr) | 2014-12-18 | 2016-06-23 | Versago Vascular Access, Inc. | Système et procédé de perméabilité de cathéter |
| US10905866B2 (en) | 2014-12-18 | 2021-02-02 | Versago Vascular Access, Inc. | Devices, systems and methods for removal and replacement of a catheter for an implanted access port |
| EP4177336A1 (fr) | 2014-12-19 | 2023-05-10 | Immusoft Corporation | Lymphocytes b pour l'administration in vivo d'agents thérapeutiques |
| AU2015380397B2 (en) | 2015-01-31 | 2021-10-21 | The Trustees Of The University Of Pennsylvania | Compositions and methods for T cell delivery of therapeutic molecules |
| CA2976656A1 (fr) | 2015-02-16 | 2016-08-25 | The Trustees Of The University Of Pennsylvania | Recepteur des cellules t entierement humain specifique de l'epitope 369-377 derive de la proteine receptrice her2/neu (erbb2) |
| CN107847869B (zh) | 2015-07-14 | 2021-09-10 | 罗门哈斯电子材料新加坡私人有限公司 | 用于过滤系统的通气装置 |
| WO2017011652A1 (fr) | 2015-07-14 | 2017-01-19 | Versago Vascular Access, Inc. | Orifices d'accès médical, dispositifs de transfert et procédés pour leur utilisation |
| CA2994549A1 (fr) | 2015-08-05 | 2017-02-09 | Lockheed Martin Corporation | Feuilles perforables de materiau a base de graphene |
| CA2994664A1 (fr) | 2015-08-06 | 2017-02-09 | Lockheed Martin Corporation | Modification par nanoparticules et perforation de graphene |
| EP3442697A4 (fr) | 2016-04-14 | 2020-03-18 | Lockheed Martin Corporation | Atténuation interfaciale sélective des défauts du graphène |
| JP2019519756A (ja) | 2016-04-14 | 2019-07-11 | ロッキード・マーチン・コーポレーション | 欠陥形成または欠陥修復をその場で監視して制御する方法 |
| KR20190018410A (ko) | 2016-04-14 | 2019-02-22 | 록히드 마틴 코포레이션 | 흐름 통로들을 갖는 2차원 막 구조들 |
| US10871487B2 (en) | 2016-04-20 | 2020-12-22 | Glusense Ltd. | FRET-based glucose-detection molecules |
| CA3042712A1 (fr) | 2016-11-03 | 2018-08-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Procedes et systemes d'evaluation en temps reel de cellules dans des dispositifs d'encapsulation avant et apres la transplantation |
| US11446133B2 (en) | 2016-11-03 | 2022-09-20 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Stacked tissue encapsulation device systems with or without oxygen delivery |
| EP3534834A4 (fr) | 2016-11-03 | 2020-05-13 | Arizona Board of Regents on behalf of the University of Arizona | Systèmes de dispositifs d'encapsulation à capteurs d'oxygène avec ou sans administration d'oxygène exogène |
| US10849731B2 (en) | 2016-11-08 | 2020-12-01 | W. L. Gore & Associates, Inc. | Cell encapsulation devices containing structural spacers |
| US11052230B2 (en) * | 2016-11-08 | 2021-07-06 | W. L. Gore & Associates, Inc. | Implantable encapsulation devices |
| US11707611B2 (en) | 2016-11-08 | 2023-07-25 | W. L. Gore & Associates, Inc. | Implantable apparatus for retention of biological moieties |
| US11338068B2 (en) | 2016-11-08 | 2022-05-24 | W. L. Gore & Associates, Inc. | Two-part implantable therapy delivery device |
| JP7088564B2 (ja) * | 2016-11-10 | 2022-06-21 | ヴィアサイト，インコーポレイテッド | 細胞送達装置におけるｐｄｘ１膵臓内胚葉細胞及びその方法 |
| USD870264S1 (en) | 2017-09-06 | 2019-12-17 | C. R. Bard, Inc. | Implantable apheresis port |
| CA3077720A1 (fr) | 2017-10-24 | 2019-05-02 | Dexcom, Inc. | Capteurs d'analyte preconnectes |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| CA3086211A1 (fr) | 2017-12-21 | 2019-06-27 | Versago Vascular Access, Inc. | Orifices d'acces medical, dispositifs de transfert et leurs procedes d'utilisation |
| EP3501559B1 (fr) | 2017-12-22 | 2021-11-17 | BIOTRONIK SE & Co. KG | Système avec implant intracardiaque et couvercle pour l'implant |
| EP3737692A4 (fr) | 2018-01-09 | 2021-09-29 | Elstar Therapeutics, Inc. | Constructions de liaison à la calréticuline et lymphocytes t modifiés pour le traitement de maladies |
| US20200367792A1 (en) | 2018-02-09 | 2020-11-26 | W.L. Gore & Associates, Inc. | Implantable access chamber and associated methods of use |
| US12152073B2 (en) | 2018-03-14 | 2024-11-26 | Marengo Therapeutics, Inc. | Multifunctional molecules that bind to calreticulin and uses thereof |
| JP2021515576A (ja) | 2018-03-16 | 2021-06-24 | イミュソフト コーポレーション | フォリスタチンを分泌するように遺伝子操作されたｂ細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
| AU2019297451A1 (en) | 2018-07-03 | 2021-01-28 | Marengo Therapeutics, Inc. | Anti-TCR antibody molecules and uses thereof |
| US20210401564A1 (en) * | 2018-09-24 | 2021-12-30 | Arizona Board Regents On Behalf Of The University Of Arizona | Methods and systems for implantable medical devices and vascularization membranes |
| EP3927747A1 (fr) | 2019-02-21 | 2021-12-29 | Marengo Therapeutics, Inc. | Molécules d'anticorps se liant à nkp30 et utilisations associees |
| CN119661722A (zh) | 2019-02-21 | 2025-03-21 | 马伦戈治疗公司 | 结合t细胞相关癌细胞的多功能分子及其用途 |
| AU2020352623A1 (en) | 2019-09-27 | 2022-05-12 | Isla Technologies, Inc. | Bioartificial pancreas |
| GB2609554B (en) | 2020-01-03 | 2025-08-20 | Marengo Therapeutics Inc | Anti-TCR antibody molecules and uses thereof |
| US11173291B2 (en) | 2020-03-20 | 2021-11-16 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11338119B2 (en) | 2020-03-20 | 2022-05-24 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| US11344526B2 (en) | 2020-03-20 | 2022-05-31 | The Regents Of The University Of California | Implantable drug delivery devices for localized drug delivery |
| CA3196876A1 (fr) | 2020-10-30 | 2022-05-05 | Klearchos Papas | Procedes et systemes pour dispositifs d'encapsulation servant a envelopper des cellules et des agents |
| WO2022175369A1 (fr) | 2021-02-19 | 2022-08-25 | F. Hoffmann-La Roche Ag | Moyens et méthodes d'implantation de cellules sécrétant un composé thérapeutique |
| WO2025096730A1 (fr) | 2023-11-01 | 2025-05-08 | University Of Virginia Patent Foundation | Nouveaux lymphocytes t car autorégulés et leurs utilisations |
| US20250152714A1 (en) | 2023-11-15 | 2025-05-15 | Immusoft Corporation | Migratory modified differentiated b cells for cancer therapy |
| WO2025147573A2 (fr) | 2024-01-05 | 2025-07-10 | Immusoft Corporation | Lymphocytes b modifiés exprimant le glp-1 pour le traitement d'une maladie métabolique |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4378016A (en) * | 1981-07-15 | 1983-03-29 | Biotek, Inc. | Artificial endocrine gland containing hormone-producing cells |
| EP0107222A1 (fr) * | 1982-09-24 | 1984-05-02 | Jean-Bernard Professeur Buchs | Prothèse pour organe artificiel hybride |
| US4479796A (en) * | 1982-11-15 | 1984-10-30 | Medtronic, Inc. | Self-regenerating drug administration device |
| WO1993000128A1 (fr) * | 1991-06-28 | 1993-01-07 | Brown University Research Foundation | Dispositif d'implant neuronal renouvelable et procede d'utilisation |
| WO1993000127A1 (fr) * | 1991-06-28 | 1993-01-07 | Brown University Research Foundation | Systeme d'implant nerveux |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1553554A (en) * | 1922-08-05 | 1925-09-15 | Paramount Rubber Company Cons | Method of making hollow rubber articles |
| US1649734A (en) * | 1923-04-16 | 1927-11-15 | Paramount Rubber Cons Inc | Method of making inflated balls |
| US2364029A (en) * | 1941-10-23 | 1944-11-28 | Jean E L Ryan | Method and apparatus for manufacture of hollow rubber articles |
| US3468096A (en) * | 1966-02-08 | 1969-09-23 | Procter & Gamble | Method of interposing a washing compound between superposed layers of nonwoven fibrous material and sealing said layers |
| CA962021A (en) * | 1970-05-21 | 1975-02-04 | Robert W. Gore | Porous products and process therefor |
| US4810868A (en) * | 1985-08-06 | 1989-03-07 | Drexler Technology Corporation | Frasable optical wallet-size data card |
| US4402694A (en) * | 1981-07-16 | 1983-09-06 | Biotek, Inc. | Body cavity access device containing a hormone source |
| US4792373A (en) * | 1985-06-18 | 1988-12-20 | Baxter Travenol Laboratories, Inc. | Heat sealing apparatus |
| US4632842A (en) * | 1985-06-20 | 1986-12-30 | Atrium Medical Corporation | Glow discharge process for producing implantable devices |
| US4718907A (en) * | 1985-06-20 | 1988-01-12 | Atrium Medical Corporation | Vascular prosthesis having fluorinated coating with varying F/C ratio |
| EP0241838B1 (fr) * | 1986-04-07 | 1992-04-15 | Agency Of Industrial Science And Technology | Matériau antithrombogène |
| US5061276A (en) * | 1987-04-28 | 1991-10-29 | Baxter International Inc. | Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation |
| US5026365A (en) * | 1987-04-29 | 1991-06-25 | The University Of Massachusetts | Method and apparatus for therapeutically treating immunological disorders and disease states |
| US5071506A (en) * | 1987-10-09 | 1991-12-10 | Thiokol Corporation | Equipment for making composite tubes including an inflatable heated bladder and a composite mold having a negative coefficient of thermal expansion |
| US5156844A (en) * | 1987-11-17 | 1992-10-20 | Brown University Research Foundation | Neurological therapy system |
| US5106627A (en) * | 1987-11-17 | 1992-04-21 | Brown University Research Foundation | Neurological therapy devices |
| US5487739A (en) * | 1987-11-17 | 1996-01-30 | Brown University Research Foundation | Implantable therapy systems and methods |
| US5182111A (en) * | 1987-11-17 | 1993-01-26 | Boston University Research Foundation | In vivo delivery of active factors by co-cultured cell implants |
| US5871472A (en) * | 1987-11-17 | 1999-02-16 | Brown University Research Foundation | Planting devices for the focal release of neuroinhibitory compounds |
| AU4072189A (en) * | 1988-02-24 | 1989-09-22 | American National Red Cross, The | Device for site directed neovascularization and method for same |
| US5188963A (en) * | 1989-11-17 | 1993-02-23 | Gene Tec Corporation | Device for processing biological specimens for analysis of nucleic acids |
| US5362308A (en) * | 1990-09-25 | 1994-11-08 | Rutgers, The State University Of New Jersey | Disposable dosage unit for iontophoresis-facilitated transdermal delivery, related devices and processes |
| US5042555A (en) * | 1990-10-01 | 1991-08-27 | Modernfold, Inc. | Floor-supported movable wall panel with height adjustment system |
| US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
| US5713888A (en) * | 1990-10-31 | 1998-02-03 | Baxter International, Inc. | Tissue implant systems |
| US5344454A (en) * | 1991-07-24 | 1994-09-06 | Baxter International Inc. | Closed porous chambers for implanting tissue in a host |
| JP3508023B2 (ja) * | 1990-10-31 | 2004-03-22 | バクスター、インターナショナル、インコーポレイテッド | 密接血管化埋め込み材料 |
| WO1993003901A1 (fr) * | 1991-08-23 | 1993-03-04 | W.R. Grace & Co. - Conn. | Dispositifs therapeutiques implantables immuno-isoles |
| US5197976A (en) * | 1991-09-16 | 1993-03-30 | Atrium Medical Corporation | Manually separable multi-lumen vascular graft |
| US5370681A (en) * | 1991-09-16 | 1994-12-06 | Atrium Medical Corporation | Polyumenal implantable organ |
| US5411550A (en) * | 1991-09-16 | 1995-05-02 | Atrium Medical Corporation | Implantable prosthetic device for the delivery of a bioactive material |
| US5192310A (en) * | 1991-09-16 | 1993-03-09 | Atrium Medical Corporation | Self-sealing implantable vascular graft |
| US5443498A (en) * | 1991-10-01 | 1995-08-22 | Cook Incorporated | Vascular stent and method of making and implanting a vacsular stent |
| US5178472A (en) * | 1991-12-11 | 1993-01-12 | The Torrington Company | Bearing for mounting on a multi-sided shaft |
| US5387237A (en) * | 1992-07-30 | 1995-02-07 | The University Of Toledo | Bioartificial pancreas |
| WO1994015663A1 (fr) * | 1992-12-30 | 1994-07-21 | Brown University Research Foundation | Procedes therapeutiques et systemes therapeutiques implantables |
| IT1269286B (it) * | 1994-12-23 | 1997-03-26 | Marco Accorsi | Procedimento per la produzione di contenitori del tipo flaconi o simili, con film in materiale sintetico termoformabile, e apparecchiatura per la sua esecuzione |
| EP0773753B1 (fr) * | 1995-06-07 | 2003-10-08 | Gore Hybrid Technologies, Inc. | Appareil de confinement implantable destine a un dispositif therapeutque |
-
1996
- 1996-06-03 EP EP96921249A patent/EP0773753B1/fr not_active Expired - Lifetime
- 1996-06-03 WO PCT/US1996/008380 patent/WO1996039993A1/fr not_active Ceased
- 1996-06-03 AU AU62511/96A patent/AU6251196A/en not_active Abandoned
- 1996-06-03 DE DE69630266T patent/DE69630266T2/de not_active Expired - Lifetime
- 1996-06-03 JP JP9500998A patent/JPH10503964A/ja not_active Ceased
- 1996-06-03 CA CA002190628A patent/CA2190628C/fr not_active Expired - Lifetime
- 1996-06-07 FR FR9607065A patent/FR2735032B1/fr not_active Expired - Lifetime
- 1996-06-07 NL NL1003300A patent/NL1003300C2/nl not_active IP Right Cessation
-
1997
- 1997-01-09 US US08/781,119 patent/US5913998A/en not_active Expired - Lifetime
- 1997-07-10 US US08/891,119 patent/US5843069A/en not_active Expired - Lifetime
-
1998
- 1998-11-30 US US09/201,173 patent/US6471687B2/en not_active Expired - Lifetime
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4378016A (en) * | 1981-07-15 | 1983-03-29 | Biotek, Inc. | Artificial endocrine gland containing hormone-producing cells |
| EP0107222A1 (fr) * | 1982-09-24 | 1984-05-02 | Jean-Bernard Professeur Buchs | Prothèse pour organe artificiel hybride |
| US4479796A (en) * | 1982-11-15 | 1984-10-30 | Medtronic, Inc. | Self-regenerating drug administration device |
| WO1993000128A1 (fr) * | 1991-06-28 | 1993-01-07 | Brown University Research Foundation | Dispositif d'implant neuronal renouvelable et procede d'utilisation |
| WO1993000127A1 (fr) * | 1991-06-28 | 1993-01-07 | Brown University Research Foundation | Systeme d'implant nerveux |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2190628C (fr) | 2000-05-30 |
| DE69630266D1 (de) | 2003-11-13 |
| EP0773753A1 (fr) | 1997-05-21 |
| DE69630266T2 (de) | 2004-09-09 |
| AU6251196A (en) | 1996-12-30 |
| CA2190628A1 (fr) | 1996-12-08 |
| EP0773753B1 (fr) | 2003-10-08 |
| JPH10503964A (ja) | 1998-04-14 |
| FR2735032B1 (fr) | 1998-01-16 |
| FR2735032A1 (fr) | 1996-12-13 |
| WO1996039993A1 (fr) | 1996-12-19 |
| US6471687B2 (en) | 2002-10-29 |
| US5913998A (en) | 1999-06-22 |
| US5843069A (en) | 1998-12-01 |
| NL1003300A1 (nl) | 1996-12-10 |
| US20020049426A1 (en) | 2002-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL1003300C2 (nl) | Implanteerbare therapeutische inrichting. | |
| NL1003302C2 (nl) | Werkwijze voor het herhaaldelijk vullen en legen van een buisvormig implanteerbaar opsluitapparaat met een therapeutische inrichting. | |
| US5411550A (en) | Implantable prosthetic device for the delivery of a bioactive material | |
| EP0604546B1 (fr) | Dispositif implantable extrudé, à lumières multiples, à porosité régulée, et méthode de fabrication | |
| US5980889A (en) | Cell encapsulating device containing a cell displacing core for maintaining cell viability | |
| AU2020210244B2 (en) | Implantable apparatus for retention of biological moieties | |
| US5782789A (en) | Macrochannel phosthetic/delivery patch | |
| AU2022202304A1 (en) | Implantable access chamber and associated methods of use | |
| ITMI961171A1 (it) | Apparecchio di contenimento impiantabile per un dispositivo terapeu- tico e metodo per caricarvi e ricaricarvi il dispositivo stesso |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AD1A | A request for search or an international type search has been filed | ||
| RD2N | Patents in respect of which a decision has been taken or a report has been made (novelty report) |
Effective date: 19961210 |
|
| PD2B | A search report has been drawn up | ||
| MK | Patent expired because of reaching the maximum lifetime of a patent |
Effective date: 20160606 |