MY133368A - Process for preparing pharmaceutical compositions for use with soft gelatin formulations - Google Patents
Process for preparing pharmaceutical compositions for use with soft gelatin formulationsInfo
- Publication number
- MY133368A MY133368A MYPI20014820A MYPI20014820A MY133368A MY 133368 A MY133368 A MY 133368A MY PI20014820 A MYPI20014820 A MY PI20014820A MY PI20014820 A MYPI20014820 A MY PI20014820A MY 133368 A MY133368 A MY 133368A
- Authority
- MY
- Malaysia
- Prior art keywords
- active ingredient
- pharmaceutically active
- concentration
- soft gelatin
- pharmaceutical compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 108010010803 Gelatin Proteins 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 229920000159 gelatin Polymers 0.000 title 1
- 239000008273 gelatin Substances 0.000 title 1
- 235000019322 gelatine Nutrition 0.000 title 1
- 235000011852 gelatine desserts Nutrition 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 5
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- 229960000905 indomethacin Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229960002009 naproxen Drugs 0.000 abstract 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 1
- 229960005489 paracetamol Drugs 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
THE INVENTION DISCLOSED HEREIN IS A PROCESS FOR INCREASING THE ACHIEVABLE CONCENTRATION OF A PHARMACEUTICALLY ACTIVE INGREDIENT RELATIVE TO FILL COMPOSITION VISCOSITY FOR DOSAGE UNITS. THE PROCESS IS PARTICULARLY USEFUL IN THE PREPARATION OF SOFT GELATIN CAPSULES CONTAINING IBUPROFEN, NAPROXEN, INDOMETHACIN, AND ACETAMINOPHEN, AS THE PHARMACEUTICALLY ACTIVE INGREDIENT. AS A RESULT OF THE PROCESS, LESSER QUANTITIES OF COMPOSITION INGREDIENTS OTHER THAN THE PHARMACEUTICALLY ACTIVE INGREDIENT ARE NEEDED TO ACCOMPLISH THE SAME THERAPEUTICALLY EFFECTIVE DOSAGE, THEREBY SIGNIFICANTLY INCREASING THE CONCENTRATION OF THE PHARMACEUTICALLY ACTIVE INGREDIENT RESULTING IN EITHER A REDUCTION IN OVERALL FILL VOLUME AND DOSAGE UNIT SIZE OR AN INCREASE IN CONCENTRATION OF PHARMACEUTICALLY ACTIVE INGREDIENT PER DOSAGE FORM.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20014820A MY133368A (en) | 2001-10-17 | 2001-10-17 | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20014820A MY133368A (en) | 2001-10-17 | 2001-10-17 | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY133368A true MY133368A (en) | 2007-11-30 |
Family
ID=78573158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20014820A MY133368A (en) | 2001-10-17 | 2001-10-17 | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY133368A (en) |
-
2001
- 2001-10-17 MY MYPI20014820A patent/MY133368A/en unknown
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