MY137618A - Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading - Google Patents
Solution composition of an oxazolidinone antibiotic drug having enhanced drug loadingInfo
- Publication number
- MY137618A MY137618A MYPI20013909A MYPI20013909A MY137618A MY 137618 A MY137618 A MY 137618A MY PI20013909 A MYPI20013909 A MY PI20013909A MY PI20013909 A MYPI20013909 A MY PI20013909A MY 137618 A MY137618 A MY 137618A
- Authority
- MY
- Malaysia
- Prior art keywords
- drug
- solution
- solution composition
- concentration
- enhanced
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 7
- 239000003814 drug Substances 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 3
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
- 239000000243 solution Substances 0.000 abstract 2
- -1 CYCLODEXTRIN COMPOUND Chemical class 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000008365 aqueous carrier Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001524 infective effect Effects 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- TYZROVQLWOKYKF-ZDUSSCGKSA-N linezolid Chemical compound O=C1O[C@@H](CNC(=O)C)CN1C(C=C1F)=CC=C1N1CCOCC1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 0.000 abstract 1
- 229960003907 linezolid Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
THERE IS PROVIDED A PHARMACEUTICAL COMPOSITION FOR THERAPEUTIC OR PROPHYLACTIC ADMINISTRATION TO A SUBJECT HAVING AN INFECTIVE DISEASE OR CONDITION OR AT RISK THEREOF. THE COMPOSITION COMPRISES AN AQUEOUS CARRIER HAVING IN SOLUTION THEREIN (A) AN OXAZOLIDINONE ANTIMICROBIAL DRUG, FOR EXAMPLE LINEZOLID, IN A THERAPEUTICALLY OR PROPHYLACTICALLY EFFECTIVE DRUG CONCENTRATION THAT IS ABOVE THE PRATICAL LIMIT OF SOLUBILITY OF THE DRUG IN A SUBSTANTIALLY ISOTONIC AQUEOUS SOLUTION AT A PHYSIOLOGICALLY COMPATIBLE PH, AND (B) A PHARMACEUTICALLY ACCEPTABLE CYCLODEXTRIN COMPOUND IN A CONCENTRATION SUFFICIENT TO MAINTAIN THE DRUG IN SOLUTION AT SUCH A DRUG CONCENTRATION. THE COMPOSITION IS PARTICULARLY USEFUL FOR INTRAVENOUS DELIVERY OF THE DRUG.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22684600P | 2000-08-22 | 2000-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY137618A true MY137618A (en) | 2009-02-27 |
Family
ID=32849339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20013909A MY137618A (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1713924A (en) |
| MY (1) | MY137618A (en) |
| ZA (1) | ZA200301281B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3095445A1 (en) * | 2009-10-13 | 2016-11-23 | Melinta Therapeutics, Inc. | Pharmaceutical compositions comprising radezolid |
| CN101766628B (en) * | 2010-01-20 | 2012-07-04 | 广东宏盈科技有限公司 | Ophthalmic bacterial-infection resisting medicine for external use |
| WO2012104874A2 (en) * | 2011-02-02 | 2012-08-09 | Mylan Laboratories Limited. | Aqueous concentrated formulation of linezolid |
| WO2013024398A2 (en) * | 2011-08-12 | 2013-02-21 | Alembic Pharmaceuticals Limited | An improved method for the quantitative determination of linezolid |
| CN102643251B (en) * | 2012-04-17 | 2016-08-10 | 四川美大康佳乐药业有限公司 | degradation impurity of linezolid and preparation method thereof |
| CN107648181B (en) * | 2016-07-25 | 2021-05-04 | 广东赛法洛药业有限公司 | Ritazodone phospholipid complex and preparation method and application thereof |
-
2001
- 2001-08-20 MY MYPI20013909A patent/MY137618A/en unknown
- 2001-08-20 CN CNA018173462A patent/CN1713924A/en active Pending
-
2003
- 2003-02-17 ZA ZA200301281A patent/ZA200301281B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200301281B (en) | 2004-02-17 |
| CN1713924A (en) | 2005-12-28 |
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