MY111055A - Pharmaceutical composition and process for the preparation thereof - Google Patents
Pharmaceutical composition and process for the preparation thereofInfo
- Publication number
- MY111055A MY111055A MYPI92002341A MYPI19922341A MY111055A MY 111055 A MY111055 A MY 111055A MY PI92002341 A MYPI92002341 A MY PI92002341A MY PI19922341 A MYPI19922341 A MY PI19922341A MY 111055 A MY111055 A MY 111055A
- Authority
- MY
- Malaysia
- Prior art keywords
- preparation
- pharmaceutical composition
- propinylamine
- phenyl
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
THE INVENTION RELATES TO TWO PHASE PHARMACEUTICAL COMPOSITIONS COMPRISING AS ACTIVE INGREDIENT A MONOAMINE OXIDASE INHIBITOR AND AN UPTAKE INHIBITOR TOGETHER WITH USUAL PHRMACEUTICAL AUXILIARIES. THE COMPOSITION CAN BE USED FOR THE TREATMENT OF NEURADEGENERATIVE DISEASES. AS ACTIVE INGREDIENT OPTIONALLY N - (1-PHENYL - ISOPROPYL) - N - METHYL - PROPINYLAMINE OR N-(4-FLUORO-PHENYL)-ISOPROP-1-YLN-METHYL-PROPINYLAMINE OR THEIR SALTS, OPTICALLY ACTIVE ISOMERS OR METABOLITES ARE USED BOTH AS MONOAMINE OXIDASE INHIBITOR AND AS UPTAKE INHIBITOR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU914060A HUT63579A (en) | 1991-12-20 | 1991-12-20 | Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY111055A true MY111055A (en) | 1999-08-30 |
Family
ID=10966728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI92002341A MY111055A (en) | 1991-12-20 | 1992-12-18 | Pharmaceutical composition and process for the preparation thereof |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5589513A (en) |
| EP (1) | EP0617615A1 (en) |
| JP (1) | JPH07502730A (en) |
| KR (1) | KR940703655A (en) |
| AU (1) | AU677170B2 (en) |
| BG (1) | BG98827A (en) |
| BR (1) | BR9206950A (en) |
| CA (1) | CA2125776A1 (en) |
| CZ (1) | CZ147494A3 (en) |
| EC (1) | ECSP930933A (en) |
| EE (1) | EE03015B1 (en) |
| FI (1) | FI942932A7 (en) |
| HU (2) | HUT63579A (en) |
| IL (1) | IL104150A (en) |
| LT (1) | LT3119B (en) |
| LV (1) | LV10386B (en) |
| MY (1) | MY111055A (en) |
| NO (1) | NO942303D0 (en) |
| NZ (1) | NZ246384A (en) |
| PH (1) | PH31073A (en) |
| PL (1) | PL172048B1 (en) |
| RO (1) | RO115785B1 (en) |
| RU (1) | RU2125448C1 (en) |
| SI (1) | SI9200404A (en) |
| SK (1) | SK74494A3 (en) |
| WO (1) | WO1993012775A1 (en) |
| ZA (1) | ZA929883B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5844003A (en) * | 1991-04-04 | 1998-12-01 | Innovations Foundation | Use of deprenyl compounds to maintain, prevent loss, or recover nerve cell function |
| US5817336A (en) * | 1993-04-02 | 1998-10-06 | Orion-Yhtyma Oy | Composition containing selegiline |
| DE4432610C1 (en) * | 1994-09-13 | 1996-02-01 | Knoll Ag | Process for the preparation of selegiline hydrochloride |
| CA2212412A1 (en) | 1995-02-10 | 1996-08-15 | The University Of Toronto Innovations Foundation | Deprenyl compounds for treatment of glaucoma |
| JP4499208B2 (en) * | 1998-10-29 | 2010-07-07 | 株式会社フジモト・コーポレーション | Novel optically active aminopentane derivatives |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| HUP9902482A2 (en) * | 1999-07-22 | 2002-04-29 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Use of p-fluoro-selegiline for producing neuroprotective pharmaceutical compositions |
| RU2194983C2 (en) * | 2000-06-30 | 2002-12-20 | Научно-исследовательский институт военной медицины | Method for evaluating blood serum neurotoxicity in patients suffering from hepatic diseases |
| EP2053033A1 (en) * | 2007-10-26 | 2009-04-29 | Bayer Schering Pharma AG | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| DE102009045056A1 (en) * | 2009-09-28 | 2011-03-31 | Henkel Ag & Co. Kgaa | Spotting preparations |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| US9498485B2 (en) | 2014-08-28 | 2016-11-22 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| JP2020503269A (en) | 2016-11-28 | 2020-01-30 | リポカイン インコーポレーテッド | Oral testosterone undecanoate therapy |
| CA3107214A1 (en) | 2018-07-20 | 2020-01-23 | Lipocine Inc. | Liver disease |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1227447B (en) * | 1962-03-30 | 1966-10-27 | Chinoin Gyogyszer Es Vegyeszet | Process for the preparation of phenylisopropylamines |
| HU193662B (en) * | 1983-12-20 | 1987-11-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing synergetic pharmaceutical composition of antidepressive aktivity |
| HU207282B (en) * | 1984-05-31 | 1993-03-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them |
| DE3764144D1 (en) * | 1986-04-16 | 1990-09-13 | Asta Pharma Ag | SYNERGISTIC COMBINATION OF AMANTADINE AND SELEGILINE. |
| HU207280B (en) * | 1986-09-25 | 1993-03-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them |
| HU197510B (en) * | 1986-12-19 | 1989-04-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing phenyl-alkyl-amine derivatives, against motion-sick |
| US4861800A (en) * | 1987-08-18 | 1989-08-29 | Buyske Donald A | Method for administering the drug deprenyl so as to minimize the danger of side effects |
| GB8807504D0 (en) * | 1988-03-29 | 1988-05-05 | Sandoz Ltd | Improvements in/relating to organic compounds |
| HU208484B (en) * | 1988-08-17 | 1993-11-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia |
| CA2037178A1 (en) * | 1990-02-28 | 1991-08-29 | Albert Walter Brzeczko | Deprenyl/l-dopa/carbidopa pharmaceutical composition |
| GB9011767D0 (en) * | 1990-05-25 | 1990-07-18 | Britannia Pharmaceuticals Ltd | Pharmaceutical compositions |
| US5169868A (en) * | 1991-03-01 | 1992-12-08 | University Of Saskatchewan | Aliphatic propargylamines as specific mao-b inhibitors |
| US5444095A (en) * | 1991-04-04 | 1995-08-22 | University Of Toronto, Innovations Foundation | Use of deprenyl to rescue damaged nerve cells |
| HU209605B (en) * | 1991-04-15 | 1994-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for production of wather-free transdermal preparation |
| US5326770A (en) * | 1992-07-17 | 1994-07-05 | The Du Pont Merck Pharmaceutical Company | Monoamine oxidase-B (MAO-B) inhibitory 5-substituted 2,4-thiazolidinediones useful in treating memory disorders of mammals |
-
1991
- 1991-12-20 HU HU914060A patent/HUT63579A/en unknown
-
1992
- 1992-12-18 CA CA002125776A patent/CA2125776A1/en not_active Abandoned
- 1992-12-18 RO RO94-01015A patent/RO115785B1/en unknown
- 1992-12-18 MY MYPI92002341A patent/MY111055A/en unknown
- 1992-12-18 RU RU94031161A patent/RU2125448C1/en active
- 1992-12-18 PH PH45474A patent/PH31073A/en unknown
- 1992-12-18 WO PCT/HU1992/000060 patent/WO1993012775A1/en not_active Ceased
- 1992-12-18 US US08/256,128 patent/US5589513A/en not_active Expired - Fee Related
- 1992-12-18 AU AU32652/93A patent/AU677170B2/en not_active Ceased
- 1992-12-18 KR KR1019940702143A patent/KR940703655A/en not_active Abandoned
- 1992-12-18 ZA ZA929883A patent/ZA929883B/en unknown
- 1992-12-18 SI SI9200404A patent/SI9200404A/en unknown
- 1992-12-18 BR BR9206950A patent/BR9206950A/en not_active Application Discontinuation
- 1992-12-18 IL IL104150A patent/IL104150A/en not_active IP Right Cessation
- 1992-12-18 CZ CZ941474A patent/CZ147494A3/en unknown
- 1992-12-18 JP JP5510411A patent/JPH07502730A/en active Pending
- 1992-12-18 PL PL92304116A patent/PL172048B1/en unknown
- 1992-12-18 EP EP93901880A patent/EP0617615A1/en not_active Withdrawn
- 1992-12-18 SK SK744-94A patent/SK74494A3/en unknown
- 1992-12-18 NZ NZ246384A patent/NZ246384A/en unknown
- 1992-12-18 FI FI942932A patent/FI942932A7/en unknown
- 1992-12-20 LV LVP-92-547A patent/LV10386B/en unknown
- 1992-12-21 LT LTIP249A patent/LT3119B/en not_active IP Right Cessation
-
1993
- 1993-05-25 EC EC1993000933A patent/ECSP930933A/en unknown
-
1994
- 1994-06-02 BG BG98827A patent/BG98827A/en unknown
- 1994-06-17 NO NO942303A patent/NO942303D0/en unknown
- 1994-08-10 EE EE9400117A patent/EE03015B1/en unknown
-
1995
- 1995-06-16 HU HU95P/P00218P patent/HU211478A9/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU3265293A (en) | 1993-07-28 |
| CZ147494A3 (en) | 1995-01-18 |
| LV10386A (en) | 1995-02-20 |
| US5589513A (en) | 1996-12-31 |
| KR940703655A (en) | 1994-12-12 |
| LTIP249A (en) | 1994-07-15 |
| HU211478A9 (en) | 1995-11-28 |
| WO1993012775A1 (en) | 1993-07-08 |
| SI9200404A (en) | 1993-06-30 |
| LV10386B (en) | 1995-12-20 |
| IL104150A (en) | 1997-11-20 |
| ZA929883B (en) | 1994-05-16 |
| EP0617615A1 (en) | 1994-10-05 |
| NZ246384A (en) | 1996-02-27 |
| ECSP930933A (en) | 1994-04-20 |
| NO942303L (en) | 1994-08-17 |
| BR9206950A (en) | 1995-11-28 |
| RO115785B1 (en) | 2000-06-30 |
| PL172048B1 (en) | 1997-07-31 |
| AU677170B2 (en) | 1997-04-17 |
| PH31073A (en) | 1998-02-05 |
| CA2125776A1 (en) | 1993-07-08 |
| FI942932A0 (en) | 1994-06-17 |
| HUT63579A (en) | 1993-09-28 |
| HU914060D0 (en) | 1992-03-30 |
| EE03015B1 (en) | 1997-08-15 |
| RU2125448C1 (en) | 1999-01-27 |
| FI942932L (en) | 1994-06-17 |
| BG98827A (en) | 1995-06-30 |
| FI942932A7 (en) | 1994-06-17 |
| JPH07502730A (en) | 1995-03-23 |
| SK74494A3 (en) | 1995-01-12 |
| LT3119B (en) | 1994-12-27 |
| NO942303D0 (en) | 1994-06-17 |
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