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Application filed by Boots Co PlcfiledCriticalBoots Co Plc
Priority to MYPI9802556priorityCriticalpatent/MY118379A/en
Publication of MY118379ApublicationCriticalpatent/MY118379A/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
AN IBUPROFEN COMPOSITION YIELDING AN AQUEOUS PREPARATION HAVING A PH OF LESS THAN 7 ON THE ADDITION OF WATER TO SAID COMPOSITION WHICH COMPRISES ONE OR MORE MEDICAMENTS INCLUDING AN IBUPROFEN MEDICAMENT WHICH FORMS AN IBUPROFEN ACTIVE INGREDIENT HAVING A MELTING POINT LESS THAN 100°C, WHEN COMBINED WITH WATER TO GIVE AN AQUEOUS PREPERATION HAVING A PH OF LESS THAN 7 AND PHOSPHOLIPID MATERIAL INTIMATELY MIXED WITH THE IBUPROFEN MEDICAMENT. THE PHOSPHOLIPID MATERIAL IS CAPABLE OF FORMING AN AQUEOUS PREPARATION COMPRISING AN AMULSION OR DISPERSION COMPRISING AN AQUEOUS PHASE SUBSTANTIALLY FREE OF SAID IBUPROFEN ACTIVE INGREDIENT AND A DISCRETE PHASE CONSISTING ESSENTIALLY OF SAID PHOSPHOLIPID MATERIAL AND INSOLUBLE PHARMACOLOGICALLY ACTIVE INGREDIENT INCLUDING SAID IBUPROFEN INGREDIENT ON THE ADDITION OF WATER TO SAID COMPOSITION. THE INVENTION ALSO PROVIDES AQUEOUS DRINK PREPARATIONS (ESPECIALLY HEATED EMULSIONS) PRODUCED THEREFROM AND A PROCESS TO PREPARE SAID AQUEOUS DRINK PREPARATIONS.